questionsmedicales.fr
Composés hétérocycliques
Composés hétérocycliques à cycles fusionnés
Composés hétérobicycliques
Purines
Purines : Questions médicales fréquentes
Termes MeSH sélectionnés :
Diagnostic
5
Hyperuricémie
Acide urique
Goutte
Analyse du liquide synovial
Maladies métaboliques
Tests génétiques
Purines
Troubles métaboliques
Symptômes
5
Hyperuricémie
Douleur articulaire
Troubles métaboliques
Fatigue
Maladie de Wilson
Troubles neurologiques
Prévention
5
Hyperuricémie
Régime alimentaire
Calculs rénaux
Hydratation
Purines
Régime alimentaire
Acide urique
Surveillance médicale
Traitements
5
Hyperuricémie
Inhibiteurs de la xanthine oxydase
Goutte
Anti-inflammatoires non stéroïdiens
Troubles métaboliques
Uricosuriques
Calculs rénaux
Hydratation
Complications
5
Goutte
Arthrite chronique
Hyperuricémie
Maladies rénales
Néphropathie urique
Hyperuricémie
Troubles métaboliques
Problèmes hépatiques
Goutte
Dommages articulaires
Facteurs de risque
5
Goutte
Antécédents familiaux
Hyperuricémie
Diurétiques
Purines
Régime alimentaire
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"name": "Comment évaluer une maladie liée aux purines ?",
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"name": "Quels symptômes des troubles des purines ?",
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"name": "Quels symptômes d'une maladie de Wilson ?",
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"position": 14,
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"position": 15,
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}
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"name": "Quel traitement pour la goutte ?",
"position": 17,
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"text": "Anti-inflammatoires non stéroïdiens (AINS) et colchicine pour soulager la douleur."
}
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"@type": "Question",
"name": "Comment prévenir les crises de goutte ?",
"position": 18,
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"name": "Quels médicaments pour les troubles des purines ?",
"position": 19,
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"name": "Comment gérer les calculs rénaux liés aux purines ?",
"position": 20,
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"@type": "Question",
"name": "Quelles complications de la goutte ?",
"position": 21,
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"text": "Arthrite chronique, dépôts de tophus et risque accru de maladies cardiovasculaires."
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"@type": "Question",
"name": "Quels risques liés à l'hyperuricémie ?",
"position": 22,
"acceptedAnswer": {
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"text": "Peut entraîner des calculs rénaux, des maladies rénales et des problèmes cardiovasculaires."
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"@type": "Question",
"name": "Comment l'hyperuricémie affecte-t-elle les reins ?",
"position": 23,
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}
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"@type": "Question",
"name": "Quelles complications des troubles des purines ?",
"position": 24,
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"text": "Peuvent inclure des problèmes hépatiques, neurologiques et des troubles métaboliques."
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"@type": "Question",
"name": "Quels effets à long terme de la goutte ?",
"position": 25,
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}
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"@type": "Question",
"name": "Quels facteurs de risque pour l'hyperuricémie ?",
"position": 26,
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"text": "Obésité, consommation excessive d'alcool, régime riche en purines et antécédents familiaux."
}
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"@type": "Question",
"name": "Qui est à risque de goutte ?",
"position": 27,
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"@type": "Question",
"name": "Quels médicaments augmentent le risque d'hyperuricémie ?",
"position": 28,
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"text": "Diurétiques, aspirine à faible dose et certains médicaments immunosuppresseurs."
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"name": "Quel rôle de l'alimentation dans les purines ?",
"position": 29,
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Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 18/04/2025
Contenu vérifié selon les dernières recommandations médicales
3 publications dans cette catégorie
Affiliations :
Institut de Biochimie et Génétique Cellulaires, CNRS, UMR 5095, Université de Bordeaux, F-33000 Bordeaux, France.
Publications dans "Purines" :
3 publications dans cette catégorie
Affiliations :
Institut de Biochimie et Génétique Cellulaires, CNRS, UMR 5095, Université de Bordeaux, F-33000 Bordeaux, France.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Division of Gastroenterology and Hepatology, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Division of Gastroenterology and Hepatology, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Division of Gastroenterology and Hepatology, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK; Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, Cambridge CB2 1GA, UK.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Division of Gastroenterology and Hepatology, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Division of Gastroenterology and Hepatology, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Division of Gastroenterology and Hepatology, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Division of Gastroenterology and Hepatology, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Division of Gastroenterology and Hepatology, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Division of Gastroenterology and Hepatology, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Division of Gastroenterology and Hepatology, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Division of Gastroenterology and Hepatology, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Division of Gastroenterology and Hepatology, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Wellcome Trust Sanger Institute, Hinxton CB10 1SA, UK.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Wellcome Trust Sanger Institute, Hinxton CB10 1SA, UK.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Division of Infectious Diseases, Department of Medicine, University of Cambridge, Cambridge CB2 0QQ, UK.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Division of Gastroenterology and Hepatology, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK. Electronic address: ak729@cam.ac.uk.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Key Laboratory of Functional Molecular Engineering of Guangdong Province, School of Chemistry and Chemical Engineering , South China University of Technology , Guangzhou 510641 , P. R. China.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Key Laboratory of Functional Molecular Engineering of Guangdong Province, School of Chemistry and Chemical Engineering , South China University of Technology , Guangzhou 510641 , P. R. China.
Publications dans "Purines" :
Point-of-care ultrasound can be used to assess muscle thickness. However, its reliability has not been fully evaluated....
This study aimed to assess the intrarater and inter-rater reliability of point-of-care ultrasound for the estimation of quadriceps and rectus femoris thickness in patients from a rehabilitation settin...
This is a cross-sectional study....
This study was conducted at the Department of Physical Medicine and Rehabilitation of a tertiary care hospital....
Twenty-nine inpatients consecutively selected after admission....
Four observers, two trained and two untrained, used point-of-care ultrasound to measure quadriceps femoris and rectus femoris thickness. Each observer performed two measurements followed by a second s...
Both intrarater and inter-rater ICC were higher than 0.888 for both quadriceps and rectus femoris measurements. Reliability was highest when ICC were calculated based on the average of two measurement...
These results suggest that point-of-care ultrasound is a reliable option to measure muscle thickness of knee extensors by the same or different observers....
Measuring knee extensors thickness may aid to adequately modulate treatment choices in patients with disability. This study suggests that quadriceps and rectus femoris muscle thickness measured after ...
To create an anatomical chart that indicates the probability of finding a motor point (MP) in different areas of the quadriceps muscle....
On 31 healthy adults, the individual anatomy of the vastus medialis (VM), rectus femoris (RF) and vastus lateralis (VL) was determined using ultrasound. Thereafter, a 3 Hz neuromuscular electrical sti...
The heat-map displayed the two best 3x3cm areas, over VL and VM respectively, each with a probability greater than 50% of finding a MP and a higher probability compared to all other areas (p <.05). RF...
Large inter-individual variations in location, and number of MPs were found, but the heat-map displayed areas with higher probability of finding a MP and can be used to facilitate NMES-application....
Ultrasonographic quantitation of quadriceps muscle mass is increasingly used for assessment of sarcopenia, but its relationship with frailty in haemodialysis recipients is not known. This study explor...
This was an exploratory analysis of a subgroup of adult prevalent (≥3 months) haemodialysis recipients deeply phenotyped for frailty. Ultrasound assessment of BATT was obtained with participants at an...
In total 223 study participants had ultrasound measurements. Frailty ranged from 34% for FP to 58% for FI. BATT was associated with increasing frailty on simple linear regression by all frailty tools,...
Ultrasound measures of quadriceps thickness is variably associated with frailty in prevalent haemodialysis recipients, dependent upon the frailty tool used, but not independent of other variables. Fur...
Clinicaltrials.gov : NCT03071107 registered 06/03/2017....
The quadriceps muscle is one of the human body's largest and most clinically important muscles and is evaluated using mid-thigh computed tomography (CT); however, its relationship with motor function ...
A total of 472 middle-aged and older community dwellers (254 men and 218 women) aged ≥40 years (mean age: 62.3 years) were included in this study. The quantity and quality of the quadriceps muscle wer...
In men, CSA and CSA×CTV were significantly associated with seven of the eight motor functions (p<0.05), excluding only balance ability. BMI-corrected CSA was significantly correlated with all eight mo...
The present results showed that a single CT image of the quadriceps muscle at the mid-thigh is useful for diagnosing sarcopenic changes, such as loss of muscle mass, muscle weakness, and muscle functi...
The number of total knee arthroplasties (TKA) has increased steadily with the aging of the population. This surgical procedure is recognized for its success in pain relief and restoration of knee func...
Muscle biopsies (VM and VL muscles) were collected from patients previously submitted to TKA via the medial parapatellar route and undergoing TKA revision (main group, n = 9) and patients with osteoar...
The normal mosaic pattern of the medial and lateral knee muscles was observed in the main and control groups, with no evidence of peripheral nerve damage. Notably, 88.9 % of the patients exhibited mil...
The medial parapatellar incision for TKA surgical access does not generate definitive morphological changes in the VM and VL muscle fibers but may contribute to VL atrophy....
This study aimed to investigate the association of muscle thickness (MT) and echo intensity (EI) obtained at different regions along the muscle length with muscle volume (MV), intramuscular adipose ti...
A total of 135 community-dwelling adults (64 men and 71 women) participated in the study. Ultrasound scanning of the rectus femoris (RF) and vastus intermedius (VI) was performed at three locations (f...
The correlation between RF-MT and RF-MV weakened as scanning approached the distal thigh, and the difference between the coefficients for the scanning locations was significant for women. However, the...
The results of this study suggest that ultrasound measurements at the distal thigh can predict MV, IntraMAT, and muscle strength of the QF to the same degree as those at the mid-thigh....
Neuromuscular electrical stimulation (NMES) of the quadriceps (Q) may increase venous blood flow to reduce the risk of venous thromboembolism. This study assessed whether Q-NMES pants could increase p...
Vibration foam rolling (VFR) intervention has recently gained attention in sports and rehabilitation settings since the superimposed vibration with foam rolling can affect several physiological system...
As females have been hypothesized to have more fatigue resistant inspiratory muscles, this study aimed to compare the development of inspiratory and leg muscle fatigue between males and females follow...
Cross-sectional comparison....
17 healthy young males (27 ± 6 years, V̇O...
Time to exhaustion was similar between sexes (p = 0.270, 95% CI -2.4 - 0.7 min). MVC of the quadriceps was lower after cycling for males (83.9 ± 11.5% vs. 94.0 ± 12.0% of baseline for females, p = 0.0...
Females incur similar peripheral fatigue in the quadriceps and inspiratory muscles compared with men following high-intensity cycling, despite smaller reduction in voluntary force. This small differen...
To measure changes in muscle thickness and echogenicity, reflecting muscle bulk and quality, respectively, of quadriceps femoris (QF), in critically ill children....
This study was done on 58 children aged 1-18 y requiring mechanical ventilation, admitted in a pediatric intensive care unit (PICU) of a tertiary care hospital from January 2018 to June 2019. QF thick...
The median muscle thickness of QF was 1.58 cm, and vastus intermedius and rectus femoris echogenicity was 35.5 and 25.88 units, respectively in the present cohort, with median age of 6 y. Only 36 of t...
There was a significant change in rectus femoris echogenicity, but not in QF thickness. Echogenicity rather than muscle thickness may be a more sensitive marker for changes in muscle properties....