questionsmedicales.fr
Composés hétérocycliques
Composés hétérocycliques à cycles fusionnés
Composés hétérobicycliques
Purines
Purines : Questions médicales fréquentes
Termes MeSH sélectionnés :
Systematic Reviews as Topic
Diagnostic
5
Hyperuricémie
Acide urique
Goutte
Analyse du liquide synovial
Maladies métaboliques
Tests génétiques
Purines
Troubles métaboliques
Symptômes
5
Hyperuricémie
Douleur articulaire
Troubles métaboliques
Fatigue
Maladie de Wilson
Troubles neurologiques
Prévention
5
Hyperuricémie
Régime alimentaire
Calculs rénaux
Hydratation
Purines
Régime alimentaire
Acide urique
Surveillance médicale
Traitements
5
Hyperuricémie
Inhibiteurs de la xanthine oxydase
Goutte
Anti-inflammatoires non stéroïdiens
Troubles métaboliques
Uricosuriques
Calculs rénaux
Hydratation
Complications
5
Goutte
Arthrite chronique
Hyperuricémie
Maladies rénales
Néphropathie urique
Hyperuricémie
Troubles métaboliques
Problèmes hépatiques
Goutte
Dommages articulaires
Facteurs de risque
5
Goutte
Antécédents familiaux
Hyperuricémie
Diurétiques
Purines
Régime alimentaire
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"@type": "Question",
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"name": "Comment évaluer une maladie liée aux purines ?",
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"name": "Quels symptômes des troubles des purines ?",
"position": 9,
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"name": "Quels symptômes d'une maladie de Wilson ?",
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"position": 14,
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"name": "Quel traitement pour la goutte ?",
"position": 17,
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"text": "Anti-inflammatoires non stéroïdiens (AINS) et colchicine pour soulager la douleur."
}
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"@type": "Question",
"name": "Comment prévenir les crises de goutte ?",
"position": 18,
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"name": "Quels médicaments pour les troubles des purines ?",
"position": 19,
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"@type": "Question",
"name": "Comment gérer les calculs rénaux liés aux purines ?",
"position": 20,
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"text": "Hydratation, modifications alimentaires et parfois intervention chirurgicale."
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"@type": "Question",
"name": "Quelles complications de la goutte ?",
"position": 21,
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"text": "Arthrite chronique, dépôts de tophus et risque accru de maladies cardiovasculaires."
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"@type": "Question",
"name": "Quels risques liés à l'hyperuricémie ?",
"position": 22,
"acceptedAnswer": {
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"text": "Peut entraîner des calculs rénaux, des maladies rénales et des problèmes cardiovasculaires."
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"@type": "Question",
"name": "Comment l'hyperuricémie affecte-t-elle les reins ?",
"position": 23,
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"text": "Peut provoquer une néphropathie urique, entraînant des lésions rénales."
}
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"@type": "Question",
"name": "Quelles complications des troubles des purines ?",
"position": 24,
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"text": "Peuvent inclure des problèmes hépatiques, neurologiques et des troubles métaboliques."
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{
"@type": "Question",
"name": "Quels effets à long terme de la goutte ?",
"position": 25,
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}
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{
"@type": "Question",
"name": "Quels facteurs de risque pour l'hyperuricémie ?",
"position": 26,
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"@type": "Answer",
"text": "Obésité, consommation excessive d'alcool, régime riche en purines et antécédents familiaux."
}
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{
"@type": "Question",
"name": "Qui est à risque de goutte ?",
"position": 27,
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"text": "Les hommes, les personnes obèses et celles ayant des antécédents familiaux de goutte."
}
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"@type": "Question",
"name": "Quels médicaments augmentent le risque d'hyperuricémie ?",
"position": 28,
"acceptedAnswer": {
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"text": "Diurétiques, aspirine à faible dose et certains médicaments immunosuppresseurs."
}
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"@type": "Question",
"name": "Quel rôle de l'alimentation dans les purines ?",
"position": 29,
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"name": "Comment l'âge influence-t-il l'hyperuricémie ?",
"position": 30,
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Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 18/04/2025
Contenu vérifié selon les dernières recommandations médicales
3 publications dans cette catégorie
Affiliations :
Institut de Biochimie et Génétique Cellulaires, CNRS, UMR 5095, Université de Bordeaux, F-33000 Bordeaux, France.
Publications dans "Purines" :
3 publications dans cette catégorie
Affiliations :
Institut de Biochimie et Génétique Cellulaires, CNRS, UMR 5095, Université de Bordeaux, F-33000 Bordeaux, France.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Division of Gastroenterology and Hepatology, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Division of Gastroenterology and Hepatology, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Division of Gastroenterology and Hepatology, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK; Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, Cambridge CB2 1GA, UK.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Division of Gastroenterology and Hepatology, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Division of Gastroenterology and Hepatology, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Division of Gastroenterology and Hepatology, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Division of Gastroenterology and Hepatology, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Division of Gastroenterology and Hepatology, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Division of Gastroenterology and Hepatology, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Division of Gastroenterology and Hepatology, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Division of Gastroenterology and Hepatology, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Division of Gastroenterology and Hepatology, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Wellcome Trust Sanger Institute, Hinxton CB10 1SA, UK.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Wellcome Trust Sanger Institute, Hinxton CB10 1SA, UK.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Division of Infectious Diseases, Department of Medicine, University of Cambridge, Cambridge CB2 0QQ, UK.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, University of Cambridge, Cambridge CB2 0AW, UK; Division of Gastroenterology and Hepatology, Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK. Electronic address: ak729@cam.ac.uk.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Key Laboratory of Functional Molecular Engineering of Guangdong Province, School of Chemistry and Chemical Engineering , South China University of Technology , Guangzhou 510641 , P. R. China.
Publications dans "Purines" :
2 publications dans cette catégorie
Affiliations :
Key Laboratory of Functional Molecular Engineering of Guangdong Province, School of Chemistry and Chemical Engineering , South China University of Technology , Guangzhou 510641 , P. R. China.
Publications dans "Purines" :
This study aimed to develop and apply a structured approach for prioritising topics for systematic reviews in public health, framed according to the readily applicable PICO format, which encourages th...
We developed a multi-stage process, consisting of a scoping and two Delphi stages with web-based surveys and invited public health stakeholders in Switzerland to participate: First, respondents specif...
In total, 215 respondents suggested 728 topics altogether. The response rate in the two Delphi stages was 91.6% and 77.6%, respectively. Most top-rated review topics focused on the effectiveness of in...
Our approach encourages involvement of stakeholders in identifying priorities for systematic reviews and highlights disparities between stakeholders and between individual criteria....
There is evidence for increased resistance against the antimicrobials used to treat keratitis. This review aims to provide global and regional prevalence estimates of antimicrobial resistance in corne...
We report this protocol following Preferred Reporting Items for Systematic Review and Meta-Analyses Protocols guidelines. We will conduct an electronic bibliographic search in MEDLINE, EMBASE, Web of ...
Ethics approval is not required as this is a protocol for a systematic review of published data. The findings of this review will be published in an open-access, peer-reviewed journal....
CRD42023331126....
The importance of systematic reviews in collating and summarising available research output on a particular topic cannot be over-emphasized. However, initial screening of retrieved literature is signi...
We implemented a Latent Dirichlet Allocation-based topic model to derive representative topics from the retrieved documents' title and abstract. The second step involves defining a score threshold for...
In one case study (helminth dataset), [Formula: see text] sensitivity compared to manual title and abstract screening was achieved. This is against a false positive rate of [Formula: see text]. For th...
Unsupervised title and abstract screening has the potential to reduce the workload involved in conducting systematic review. While sensitivity of the methodology on the tested data is low, approximate...
Tranexamic acid (TXA) has become a widely used antifibrinolytic drug for reducing bleeding in surgery. However, adverse events, such as seizures, pulmonary embolism and deep vein thrombosis, limit its...
We will search the PubMed, Cochrane Central Register of Controlled Trials, Embase, Web of Science and China National Knowledge Internet databases using a strategy that combines the terms TXA, randomis...
CRD42021281206....
Androgenetic alopecia is a widespread condition that is the most common type of hair loss affecting approximately 58% and 40% of men and women by the age of 50, respectively. Patients have been known ...
Fear of falling (FoF) is a major challenge for the quality of life among older adults. Despite extensive work in previous scoping and systematic reviews on separate domains of FoF and interventions re...
Following the guidelines of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses-Extension for Scoping Reviews (PRISMA-ScR), seven main databases will be searched from 2000 to the da...
No ethics approval is required for the review. The results will be submitted to a peer-reviewed journal and presented at academic conferences. The outcomes will be disseminated through social media, o...
The scoping review was registered with the Open Science Framework (https://osf.io/gyzjq)....
Systematic reviews and meta-analyses are proliferating as they are an important building block to inform evidence-based guidelines and decision-making. Enforcement of best practice in clinical trials ...
We conducted a comprehensive assessment of all literature examining problems, which relate to published systematic reviews....
The first iteration of our living systematic review (https://systematicreviewlution.com/) has found 485 articles documenting 67 discrete problems relating to the conduct and reporting of systematic re...
Many hundreds of articles highlight that there are many flaws in the conduct, methods, and reporting of published systematic reviews, despite the existence and frequent application of guidelines. Cons...
The introduction of new medical technologies such as sensors has accelerated the process of collecting patient data for relevant clinical decisions, which has led to the introduction of a new technolo...
This study aims to assess the methodological quality and quality of evidence from meta-analyses of digital biomarker-based interventions....
This study follows the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guideline for reporting systematic reviews, including original English publications of systematic rev...
A total of 25 studies with 91 reported outcomes were included in the final analysis; 1 (4%), 1 (4%), and 23 (92%) studies had high, low, and critically low methodologic quality, respectively. As many ...
Researchers in this field should consider the AMSTAR-2 criteria and GRADE to produce high-quality studies in the future. In addition, patients, clinicians, and policymakers are advised to consider the...
RR2-10.2196/28204....
the COVID-19 infection, caused by severe Coronavirus 2 syndrome (Sars-Cov-2), immediately appeared to be the most tragic global pandemic event of the twentieth century. Right from the start of the pan...
This study aimed to review the currently available evidence on the effectiveness of administering tranexamic acid (TXA) to patients undergoing orthognathic surgery....
A study protocol was developed in accordance with the Preferred Reporting Guideline for Overviews of Reviews (PRIOR) and registered on the International Prospective Register of Systematic Reviews (PRO...
The search strategy yielded a total of 50 articles. After reading the abstracts, 28 articles were excluded, and the English full texts of the remaining 22 studies were separately examined for eligibil...
Within the limits of the present study and the reviews of the 7 articles included, it is observed that TXA is able to reduce the amount of intraoperative blood loss and the amount of irrigation fluids...