Cold Spring Harbor Laboratory, 1 Bungtown Rd, Cold Spring Harbor, NY 11724, USA.
Present address: Institute for Quantitative Biosciences, the University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo, 1130032, Japan.
Present address: Department of Life Sciences, Graduate School of Arts and Sciences, the University of Tokyo, 3-8-1 Komaba, Meguro-ku, Tokyo, 1538902, Japan.
Food Quality Perception & Society Team, iSENSE Lab, Department of Food Science, Aarhus University, Aarhus, Denmark; Sino-Danish College (SDC), University of Chinese Academy of Sciences, Beijing, China.
Department of Psychology, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, USA.
Center for the Neural Basis of Cognition, Pittsburgh, Pennsylvania 15213, USAuoszczap@andrew.cmu.edu, hellerl@andrew.cmu.edu, seojunj@andrew.cmu.edu, banance@andrew.cmu.edu.
Department of Psychology, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, USA.
Center for the Neural Basis of Cognition, Pittsburgh, Pennsylvania 15213, USAuoszczap@andrew.cmu.edu, hellerl@andrew.cmu.edu, seojunj@andrew.cmu.edu, banance@andrew.cmu.edu.
Consultant Neurologist & Honorary Clinical Associate Professor of Neurology, Department of Neurology, Leeds General Infirmary, Great George Street, Leeds LS1 3EX, UK. Electronic address: melissamaguire@nhs.net.
International Islamic University Malaysia, Kulliyyah of Allied Health Sciences, Department of Audiology and Speech Language Pathology, Kuantan, Pahang, Malaysia.
International Islamic University Malaysia, Kulliyyah of Allied Health Sciences, Department of Audiology and Speech Language Pathology, Kuantan, Pahang, Malaysia. sarahrahmat@iium.edu.my.
International Islamic University Malaysia, Kulliyyah of Allied Health Sciences, Department of Audiology and Speech Language Pathology, Kuantan, Pahang, Malaysia.
International Islamic University Malaysia, Kulliyyah of Allied Health Sciences, Department of Optometry and Visual Sciences, Kuantan, Pahang, Malaysia.
Frailty has been associated with a decline in sensory and motor function. However, given that different frailty measures were shown to overlap but also differ in their diagnostic properties, sensory a...
Data from 44 pre-frail and frail subjects aged 65 and above were used. Frailty was measured using the FP and the FI. Sensory function in the visual, auditory, and tactile domain was assessed using vis...
The frailty measures were moderately correlated (0.497, p ≤ 0.01) and had a Kappa agreement of 0.467 (p = 0.002). Using the FP, frailty was significantly associated with reduced upper extremity motor ...
Frailty is related to reduced performance in measures of sensory and motor function. However, traditional measures of frailty might be differentially sensitive to capture sensory and motor decline, po...
ClinicalTrials.gov NCT03666039 . Registered 11 September 2018 - Retrospectively registered....
Frailty is one of the most important problems in a super-aged society. It is necessary to identify frailty quickly and easily at the bedside. We developed a simple patient-reported frailty screening s...
Frailty is the incremental accumulation of minute defects that progressively impair health and performance. Frailty is commonly observed in older adults; however, secondary frailty may also occur in p...
To assess the impact of frailty in patients with ovarian cancer on surgical procedures and outcomes....
A retrospective review of patients with stage II-IV ovarian cancer from April 2013 to September 2017 was performed. Patients were triaged by laparoscopy to determine primary resectability. The adjuste...
592 patients met inclusion criteria; amFI of 0, 1 and ≥ 2 was noted in 57%, 29%, and 14%, respectively. Patients with high frailty were less likely to be offered laparoscopic assessment for primary su...
Postoperative morbidity, PFS, and OS were worse in patients with high frailty scores. Quantification of frailty may be useful for clinical decision making in patients with newly diagnosed advanced ova...
This study aims to examine the associations between midlife Life's Simple 7 (LS7) status, psychosocial health (social isolation and loneliness), and late-life multidimensional frailty indicators, and ...
The Clinical Frailty Scale (CFS) is a simple and validated tool for assessing frailty, and higher CFS scores are correlated with worse perioperative outcomes after cardiovascular surgery. However, the...
We retrospectively analyzed data from 561 patients with esophageal cancer (EC) who underwent resection from August 2010 to August 2020. We defined a CFS score of ≥4 as indicative of frailty; thus, pat...
Of the 561 patients, 90 (16%) had frailty and 471 (84%) did not. Frail patients had a significantly older age, lower body mass index, higher American Society of Anesthesiologists physical status class...
Preoperative frailty was associated with shorter OS after resection of EC. The CFS score may be a prognostic biomarker for patients with EC, especially early-stage EC....
With the topical focus on the prevention of and countermeasures for frailty, scattered studies have subdivided its social elements and aspects as "social frailty." While the concepts and definition of...
Frailty is a common condition present in older Emergency Department (ED) patients that is associated with poor health outcomes. The Clinical Frailty Scale (CFS) is a tool that measures frailty on a sc...
We performed a systemic literature search to identify original research that used the CFS in emergency medicine. Several databases were searched from January 2005 to July 2021. Two independent reviewe...
A total of 4818 unique citations were identified; 34 studies were included in the final analysis. Among them, 76% were published after 2018, mainly in Europe or North America (79%). Only two assessed ...
The use of CFS in emergency medicine research is drastically increasing. However, the reporting is not optimal and should be more standardized. Studies evaluating the impact of frailty assessment in t...
https://doi.org/10.17605/OSF.IO/W2F8N....
To test the agreement of the Clinical Frailty Scale (CFS) and the Tilburg Frailty Indicator (TFI), their association with 3, 6 months and 1-year mortality and the trajectory of frailty in a mixed popu...
This is a prospective, multicenter, longitudinal study on ICU survivors ≥18 years old with an ICU stay >72 h. For each patient, sociodemographic and clinical data were collected. Frailty was assessed ...
124 patients with a mean age of 66 years old were enrolled. The baseline prevalence of frailty was 15.3% by CFS and 44.4% by TFI. Baseline CFS and TFI correlated but showed low agreement (Cohen's K = ...
CFS and TFI identify different populations of frail ICU survivors. Frail patients before ICU according to CFS have a significantly higher mortality after ICU discharge. The CFS during follow-up is an ...
Muscles and bones are intricately connected tissues displaying marked co-variation during development, growth, aging, and in many diseases. While the diagnosis and treatment of osteoporosis are well e...
