Comment diagnostiquer une vascularite ?

Le diagnostic repose sur des analyses sanguines, des biopsies et des examens d'imagerie.

Quels tests sanguins sont utilisés ?

Des tests comme la vitesse de sédimentation et les marqueurs inflammatoires sont courants.

Quels symptômes indiquent une vascularite ?

Symptômes incluent fatigue, fièvre, douleurs articulaires et éruptions cutanées.

La biopsie est-elle toujours nécessaire ?

Non, elle est souvent utilisée si les tests sanguins ne sont pas concluants.

Quels spécialistes consultent pour une vascularite ?

Les rhumatologues et les médecins internistes sont souvent impliqués dans le diagnostic.

Quels sont les symptômes courants de la vascularite ?

Les symptômes incluent fatigue, fièvre, douleurs musculaires et éruptions cutanées.

La vascularite peut-elle causer des douleurs articulaires ?

Oui, les douleurs articulaires sont fréquentes et peuvent être sévères.

Y a-t-il des symptômes neurologiques associés ?

Oui, des maux de tête, des troubles de la vision et des engourdissements peuvent survenir.

Les éruptions cutanées sont-elles spécifiques ?

Elles peuvent varier, mais souvent apparaissent sous forme de plaques ou de purpura.

La vascularite peut-elle affecter les organes internes ?

Oui, elle peut toucher les reins, les poumons et le cœur, entraînant des complications.

Peut-on prévenir la vascularite ?

Il n'existe pas de méthode de prévention spécifique, mais un suivi médical régulier aide.

Les vaccinations sont-elles recommandées ?

Oui, les vaccinations peuvent aider à prévenir certaines infections qui aggravent la vascularite.

Comment éviter les déclencheurs ?

Éviter le tabac, le stress et les infections peut réduire les risques de poussées.

Le suivi médical est-il important ?

Oui, un suivi régulier permet d'ajuster le traitement et de surveiller les symptômes.

Y a-t-il des conseils diététiques ?

Une alimentation équilibrée et riche en antioxydants peut soutenir la santé vasculaire.

Quels traitements sont disponibles pour la vascularite ?

Les corticostéroïdes et les immunosuppresseurs sont couramment utilisés.

Les corticostéroïdes sont-ils efficaces ?

Oui, ils réduisent l'inflammation et soulagent les symptômes rapidement.

Quand utilise-t-on des immunosuppresseurs ?

Ils sont utilisés pour les cas graves ou réfractaires aux corticostéroïdes.

Y a-t-il des traitements alternatifs ?

Des thérapies biologiques peuvent être envisagées dans certains cas spécifiques.

Le traitement est-il à long terme ?

Cela dépend de la gravité et de la réponse au traitement, souvent plusieurs mois.

Quelles sont les complications possibles de la vascularite ?

Les complications incluent des lésions organiques, des AVC et des problèmes cardiaques.

La vascularite peut-elle entraîner des problèmes rénaux ?

Oui, elle peut causer une insuffisance rénale aiguë ou chronique.

Quels risques cardiovasculaires sont associés ?

Les patients peuvent avoir un risque accru de maladies cardiaques et d'AVC.

Les complications sont-elles réversibles ?

Certaines complications peuvent être réversibles avec un traitement précoce.

Comment surveiller les complications ?

Des examens réguliers et des tests de fonction organique sont essentiels.

Quels sont les facteurs de risque de la vascularite ?

Les facteurs incluent des antécédents familiaux, des infections et certains médicaments.

L'âge influence-t-il le risque de vascularite ?

Oui, certaines formes de vascularite sont plus fréquentes chez les personnes âgées.

Les infections peuvent-elles déclencher une vascularite ?

Oui, des infections virales ou bactériennes peuvent être des déclencheurs.

Le tabagisme est-il un facteur de risque ?

Oui, le tabagisme est associé à un risque accru de vascularite.

Certaines maladies auto-immunes augmentent-elles le risque ?

Oui, des maladies comme le lupus ou la polyarthrite rhumatoïde sont des facteurs de risque.

Vascularite - Informations médicales vérifiées

Classification of Local Recurrence After Nipple-Sparing Mastectomy Based on Location: The Features of Nipple-Areolar Recurrence Differ from Those of Other Local Recurrences.

Mar 2023

DOI: 10.1245/s10434-022-12760-1 PMID: 36371582

Little information is available about the clinical and pathologic characteristics of local recurrence (LR) after nipple-sparing mastectomy according to the locations of LR.... This study classified 99 patients into the following two groups according to the location of LR after nipple-sparing mastectomy: nipple-areolar recurrence (NAR) group and other locations of LR (oLR) g... For about half of the patients (44.4 %) with NAR, the primary cancer was estrogen receptor (ER)-negative and human epidermal growth factor receptor 2 (HER2)-positive. Conversely, in most of the patien... This multi-institutional retrospective study demonstrated that the features of NAR, such as the characteristics of the primary and recurrent tumors and the prognostic factors after LR resection, were ...

Humans Female Breast Neoplasms Mastectomy Nipples +4 autres

Feasibility of local therapy for recurrent pancreatic cancer.

Sep 2022

DOI: 10.1016/j.pan.2022.05.004 PMID: 35641368

Despite advances in perioperative management, recurrence after curative pancreatectomy is a critical issue in the treatment of pancreatic ductal adenocarcinoma (PDAC). The significance of local therap... We reviewed the medical records of patients with PDAC who underwent curative resection at our institution between January 2009 and December 2019. We examined the patterns of relapse and assessed the c... A total of 246 patients with PDAC who underwent R0 or R1 resection were included in this study. The 3-year overall survival (OS) rate was 39.8%, and the 1-year recurrence-free survival rate was 51.2% ... Our results suggest that a multimodal approach may improve the clinical outcomes of patients with recurrent PDAC....

Adenocarcinoma Carcinoma, Pancreatic Ductal Feasibility Studies Humans Neoplasm Recurrence, Local +6 autres

Ultrasound Assessment of Skin Tumors Local Recurrence.

Oct 2023

DOI: 10.1002/jum.16255 PMID: 37195073

Skin cancer may recur at or around the surgical site despite wide excisions. Prompt clinical and sonographic detection of local recurrence is important since subjects with relapsing melanomas or nonme...

Humans Skin Neoplasms Skin Melanoma Ultrasonography +1 autres

Pathological determinants of outcome following resection of locally advanced or locally recurrent rectal cancer.

Nov 2023

DOI: 10.1016/j.ejso.2023.06.023 PMID: 37442715

Pathological factors that influence and predict survival following pelvic exenteration (PE) for locally advanced (LARC) or locally recurrent rectal cancer (LRRC), especially LRRC, remain poorly unders... A retrospective cohort study was performed for all patients undergoing a curative PE for LARC or LRRC between 2008 and 2021 at a tertiary referral UK specialist colorectal hospital. Cox regression ana... 388 patients were included in the analysis with 256 resections for LARC and 132 for LRRC. 62.4% of patients were male with a median age of 59 years (IQR 49-67). 247 (64%) partial pelvic exenterations ... A positive resection margin and poorly differentiated tumours are significant negative prognostic markers for survival and recurrence in LARC. The results of this study support the need to look for al...

Humans Male Middle Aged Aged Female +7 autres

Intraparenchymal metastases as a cause for local recurrence of pancreatic cancer.

Feb 2023

DOI: 10.1111/his.14839 PMID: 36371607

Using CODA, a technique for three-dimensional reconstruction of large tissues, Kiemen et al. report observation of a microscopic focus of pancreatic cancer found in the vasculature of grossly normal h...

Humans Pancreatic Neoplasms Pancreas Neoplasm Recurrence, Local Pancreatic Neoplasms

Does the Addition of Mutations of CTNNB1 S45F to Clinical Factors Allow Prediction of Local Recurrence in Patients With a Desmoid Tumor? A Local Recurrence Risk Model.

01 10 2023

DOI: 10.1097/CORR.0000000000002627 PMID: 37104792

The initial approach to the treatment of desmoid tumors has changed from surgical resection to watchful waiting. However, surgery is still sometimes considered for some patients, and it is likely that... We sought to explore whether a combined molecular and clinical prognostic model for relapse in patients with desmoid tumors treated with surgery would allow us to identify patients who might do well w... This was a retrospective, single-center study of 107 patients with desmoid tumors who were surgically treated between January 1980 and December 2015, with a median follow-up of 106 months (range 7 to ... The multivariable analysis showed that S45F mutations (hazard ratio 5.25 [95% confidence interval 2.27 to 12.15]; p < 0.001) and tumor in the extremities (HR 3.15 [95% CI 1.35 to 7.33]; p = 0.008) wer... CTNNB1 S45F mutations combined with other clinical variables are a potential prognostic biomarker associated with the risk of relapse in patients with desmoid tumors. The developed nomogram is simple ... Level III, therapeutic study....

Humans Fibromatosis, Aggressive Retrospective Studies Neoplasm Recurrence, Local Mutation +2 autres

Risk Factors of Second Local Recurrence in Surgically Treated Recurrent Brain Metastases: An Exploratory Analysis.

Nov 2022

DOI: 10.1016/j.wneu.2022.08.066 PMID: 36028114

A first local recurrence is common after resection or radiotherapy for brain metastasis (BM). However, patients with BMs can develop multiple local recurrences over time. Published data on second loca... Patients were identified from a database at Brigham and Women's Hospital in Boston. Hazard ratios and 95% confidence intervals for predictors of a second local recurrence were computed using a Cox pro... Of 170 identified surgically treated first locally recurrent lesions, 74 (43.5%) progressed to second locally recurrent lesions at a median of 7 months after craniotomy. Subtotal resection of the firs... A second local recurrence occurred after 43.5% of craniotomies for first recurrent lesions. Subtotal resection and infratentorial location were the strongest risk factors for worse second local recurr...

Humans Female Neoplasm Recurrence, Local Prognosis Risk Factors +3 autres

Applying a neoscore in locally advanced rectal cancer is beneficial in predicting local recurrences after surgery.

2023

DOI: 10.1371/journal.pone.0285709 PMID: 37172066

The current study was undertaken to provide more detailed prognostic models for early prediction of local recurrences and local recurrence free survival (RFS) using different radiologic and pathologic... One hundred patients with locally advanced rectal carcinomas decided to receive neoadjuvant CRT were retrospectively recruited, Hazard ratios (HR) were determined in the two cox regression models and ... HR of 1st group of models: T+N, T+N+G, T+N+G+S, T+N+G+S+PNI, and T+N+G+S+PNI+R were summated and categorized into scores, these scores were significantly correlated with the risk of recurrence (Somer'... We propose that the addition of biologic factors to staging of rectal cancer provide precise stratification and association with local recurrences in patients received preoperative CRT....

Humans Retrospective Studies Prognosis Rectum Rectal Neoplasms +6 autres

Surgery of resectable local recurrence following colorectal cancer: Compartmental surgery improves local control.

Nov 2022

DOI: 10.1002/jso.26990 PMID: 35779039

This study aims to identify prognostic factors and define the best extent of surgery for optimizing treatment of local recurrence (LR) following colorectal cancer (CRC).... An institutional database of consecutive patients who underwent radical resection (R0/R1) of LR following CRC was analyzed prospectively from 2010 to 2021 at one tertiary cancer center.... In this study, 75 patients were included with LR following CRC and analyzed. Patients were categorized as compartmental resections (CompRe) (n = 47) if all adjacent organs were systematically removed,... Complete compartmental surgery is safe and improves local control. Optimal LR resection needs to remove all contiguous organs, with or without tumor involvement....

Colorectal Neoplasms Digestive System Surgical Procedures Humans Neoplasm Recurrence, Local Prognosis +3 autres

Recurrent RET fusions in fibrosarcoma-like neoplasms in adult viscera: expanding the clinicopathological and genetic spectrum.

Mar 2023

DOI: 10.1111/his.14847 PMID: 36443894

RET-fused mesenchymal neoplasms mostly affect the soft tissue of paediatric patients. Given their responsiveness to selective RET inhibitors, it remains critical to identify those extraordinary cases ... Clinicopathological features were assessed and partner agnostic targeted next-generation sequencing on clinically validated platforms were performed. The patients were 18, 53, and 55 years old and inc... Our study expands the clinicopathological and genetic spectrum of mesenchymal neoplasms associated with RET fusions....

Female Humans Male Adult Child +7 autres

Vascularite : Questions médicales fréquentes

Termes MeSH sélectionnés :

Questions fréquentes et termes MeSH associés

Diagnostic 5

Symptômes 5

Prévention 5

Traitements 5

Complications 5

Facteurs de risque 5

Contenu validé par Dr Olivier Menir

Sous-catégories

Aortite

Artérite

Syndrome de Cogan

Phlébite

Vascularite rétinienne

Vascularite systémique

Thromboangéite oblitérante

Endartérite

Thrombophlébite

Syndrome de Lemierre

Auteurs principaux

Sources (10000 au total)