Oui, les traitements sont souvent adaptés en fonction des symptômes et de la gravité.
Traitement personnaliséSymptômes
Complications
5
#1
Quelles complications peuvent survenir avec une malformation de l'aqueduc ?
Les complications incluent des troubles de l'équilibre, des pertes auditives et des infections.
ComplicationsTroubles de l'équilibre
#2
Les infections de l'oreille sont-elles une complication fréquente ?
Oui, les malformations peuvent augmenter le risque d'infections de l'oreille.
Infections de l'oreilleMalformations
#3
Les troubles de l'équilibre peuvent-ils être permanents ?
Oui, certains patients peuvent souffrir de troubles de l'équilibre permanents.
Troubles de l'équilibreDysfonction vestibulaire
#4
Les complications auditives peuvent-elles s'aggraver avec le temps ?
Oui, sans traitement, les pertes auditives peuvent s'aggraver avec le temps.
Pertes auditivesComplications
#5
Y a-t-il un risque de développement de troubles neurologiques ?
Dans certains cas, des troubles neurologiques peuvent se développer en raison de complications.
Troubles neurologiquesComplications
Facteurs de risque
5
#1
Quels sont les facteurs de risque pour les malformations de l'aqueduc ?
Les antécédents familiaux et certaines conditions génétiques augmentent le risque.
Facteurs de risqueConditions génétiques
#2
Les infections pendant la grossesse peuvent-elles affecter l'aqueduc ?
Oui, certaines infections pendant la grossesse peuvent augmenter le risque de malformations.
Infections pendant la grossesseMalformations congénitales
#3
L'exposition à des toxines est-elle un facteur de risque ?
Oui, l'exposition à certaines toxines environnementales peut augmenter le risque.
Toxines environnementalesFacteurs de risque
#4
Les anomalies chromosomiques sont-elles liées à l'aqueduc ?
Oui, certaines anomalies chromosomiques peuvent être associées à des malformations de l'aqueduc.
Anomalies chromosomiquesMalformations
#5
L'âge parental joue-t-il un rôle dans les malformations ?
Oui, l'âge avancé des parents peut être un facteur de risque pour certaines malformations.
Âge parentalFacteurs de risque
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European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
2022-10-10
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
Case Western Reserve University School of Medicine, Cleveland, OH, USA; Department of Radiology, University Hospitals Cleveland Medical Center, Cleveland, OH, USA.
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
2022-03-08
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
Centre for Speech and Language Therapy and Hearing Science, Cardiff School of Sport and Health Sciences Cardiff Metropolitan University Cardiff United Kingdom.
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
Ureteric carcinoma is the rarest of all urothelial malignancies, and little attention has been given to it. Palliation in these groups of patients is a dilemma in the clinics. Use of chemotherapeutic ...
carcinoma; case reports; metastasis; paclitaxel....
The escalating prevalence of bladder cancer, particularly urothelial carcinoma, necessitates innovative approaches for prognosis and therapy. This study delves into the significance of genes related t...
The South West Oncology Group's 2000 randomised-control trial investigated the addition of maintenance intravesical bacillus Calmette-Guerin (BCG) to non-muscle invasive urothelial carcinoma (NMIUC) t...
A growing number of investigations have suggested a close link between cancer stem cells (CSCs), epithelial-to-mesenchymal transition (EMT), and the tumor microenvironment (TME). However, the relation...
We first explored biomarkers of tumor stemness (TS) by single-cell sequencing analysis. Then, subtypes of bladder urothelial carcinoma (BLCA) were identified using clustering analysis based on TS biom...
Three TS clusters and two TS-related gene clusters were identified with differential EMT activity status, CSC features, and TME characteristics in BLCA. Then, a TS scoring system was established with ...
Overall, this research provides a better understanding of tumor invasion and metastasis mechanisms through an analysis of TS patterns with different EMT processes and CSC characteristics. The TS score...
Transitional cell carcinoma is considered the most predominant type of bladder cancer. Bladder can cer can also be found as squamous cell carcinoma that accounts for 5% of the total bladder cancer due...
Using 150 archival tissue blocks from human bladder cancer cases to detect expression of SNAIL/SLUG and Twist2 in relation to loss of E-cadherin by immunohistochemical method....
Our results have revealed that in squamous cell carcinoma 40 specimens showed marked Twist 2 expression, and 30 specimens showed marked snail/slug biomarkers expression while poorly differentiated can...
Detection of SNAIL/SLUG and Twist 2 biomarkers in urothelial cancer is an important predictor for the loss of E-cadherin, a cornerstone in urinary bladder cell adhesion and its loss in urothelial carc...
At present, there are few studies on renal pelvic transitional cell carcinoma (RPTCC) in elderly patients in the literature. The study aims to establish a new nomogram of cancer-specific survival (CSS...
This study downloaded the data of 1375 elderly patients with T1-T3N0M0 RPTCC in the Surveillance, Epidemiology, and Final Results (SEER) database from 2004 to 2018. Patients were randomly divided into...
We found that the risk factors affecting CSS in elderly patients with T1-T3N0M0 RPTCC are surgery, AJCC stage, laterality, tumor size, histological grade, and tumour laterality. Based on these factors...
In this study, the SEER database was used for the first time to create and validate a new nomogram prediction model for elderly patients with T1-T3N0M0 RPTCC. Compared with the traditional AJCC stage ...
Cisplatin (CDDP)-based chemotherapy is the standard of care in patients with muscle-invasive bladder cancer. However, in a large number of cases, the disease becomes resistant or does not respond to C...
Epithelial-mesenchymal transition (EMT) and aberrant energy metabolism are pivotal biological processes in tumor progression, significantly impacting tumor prognosis. However, the relationship between...
Bladder cancer samples from The Cancer Genome Atlas were categorized into two groups via clustering analysis to elucidate disparities in expression, prognostic significance, and immune infiltration of...
Cluster analysis revealed significant differences in the expression of genes associated with EMT and energy metabolism between the two groups. Group 2 exhibited significantly improved overall survival...
EMT and energy metabolism exert pivotal influences on the immune microenvironment in BLCA. CSPG4 holds promise as a prognostic biomarker for patients with BLCA, offering valuable insights into potenti...
Nivolumab is used after platinum-based chemotherapy in patients with metastatic urothelial carcinoma. Studies suggest improved outcomes for dual checkpoint inhibition with high ipilimumab doses. We ai...
TITAN-TCC is a multicentre, single-arm, phase 2 trial done at 19 hospitals and cancer centres in Germany and Austria. Adults aged 18 years or older with histologically confirmed metastatic or surgical...
Between April 8, 2019, and Feb 15, 2021, 83 patients with metastatic urothelial carcinoma were enrolled and all received nivolumab induction treatment (intention-to-treat population). The median age o...
Treatment with nivolumab and nivolumab plus ipilimumab boosts in early non-responders and patients who progress late significantly improved objective response rate after previous platinum-based chemot...
Bristol Myers Squibb....
Urothelial carcinoma is a major subtype of bladder cancer and small cell carcinoma (SCC) is a rare type of cancer in clinical practice. Pathologic collision of urinary bladder urothelial carcinoma wit...
Here, we report a patient with high-grade papillary carcinoma which changed to collision tumor with SCC. The patient underwent radical cystectomy; however, neck and mediastinum lymph nodes metastases ...
We hypothesized the mechanism underlying this pathological transformation. For patients with urothelial bladder cancer, pathological analysis should be conducted to allow standardized and persistent t...
We recommend that radical cystectomy be performed early enough for patients with non-muscle invasive bladder cancer, who are at a high risk of tumor recurrence. However, this conclusion needs to be va...