questionsmedicales.fr
Phénomènes microbiologiques
Phénomènes physiologiques viraux
Réplication virale
Activation virale
Activation virale : Questions médicales fréquentes
Termes MeSH sélectionnés :
B-Cell Maturation Antigen
Diagnostic
5
Diagnostic
Infections virales
Tests de diagnostic
Virus
Symptômes
Infections virales
Biopsie
Infections virales
Symptômes
5
Symptômes
Infections virales
Complications
Infections virales
Symptômes
Maladies infectieuses
Prévention
5
Hygiène
Infections virales
Masques
Prévention des maladies
Voyages
Infections virales
Comportements à risque
Infections virales
Traitements
5
Traitement antiviral
Infections virales
Antibiotiques
Infections virales
Vaccins
Prévention des maladies
Complications
5
Complications
Infections virales
Maladies chroniques
Infections virales
Complications
État de santé
Gestion des complications
Infections virales
Facteurs de risque
5
Facteurs de risque
Infections virales
Maladies chroniques
Infections virales
Mode de vie
Infections virales
Stress
Infections virales
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"@type": "Question",
"name": "Quels tests sont utilisés pour détecter les virus activés ?",
"position": 2,
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"@type": "Question",
"name": "Les symptômes aident-ils au diagnostic ?",
"position": 3,
"acceptedAnswer": {
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"text": "Oui, les symptômes cliniques orientent souvent vers une activation virale."
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"name": "Peut-on détecter un virus inactif ?",
"position": 4,
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"name": "Les biopsies sont-elles utiles pour le diagnostic ?",
"position": 5,
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"@type": "Question",
"name": "Quels sont les symptômes d'une activation virale ?",
"position": 6,
"acceptedAnswer": {
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"@type": "Question",
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"position": 7,
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"@type": "Question",
"name": "L'activation virale cause-t-elle des complications ?",
"position": 8,
"acceptedAnswer": {
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"text": "Oui, elle peut entraîner des complications graves comme des pneumonies ou des encéphalites."
}
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{
"@type": "Question",
"name": "Les symptômes apparaissent-ils rapidement ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Ils peuvent apparaître rapidement ou après une période d'incubation prolongée."
}
},
{
"@type": "Question",
"name": "Peut-on avoir des symptômes sans activation virale ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, d'autres maladies peuvent provoquer des symptômes similaires sans activation virale."
}
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{
"@type": "Question",
"name": "Comment prévenir l'activation virale ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "La vaccination, l'hygiène et l'évitement des contacts sont essentiels."
}
},
{
"@type": "Question",
"name": "Le lavage des mains aide-t-il à prévenir les infections ?",
"position": 12,
"acceptedAnswer": {
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"text": "Oui, un bon lavage des mains réduit le risque de transmission virale."
}
},
{
"@type": "Question",
"name": "Les masques protègent-ils contre les virus ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les masques peuvent réduire la transmission des virus respiratoires."
}
},
{
"@type": "Question",
"name": "Les voyages augmentent-ils le risque d'activation virale ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les voyages peuvent exposer à de nouveaux virus et augmenter le risque."
}
},
{
"@type": "Question",
"name": "Les comportements à risque augmentent-ils l'activation virale ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des comportements comme le partage d'aiguilles augmentent le risque d'infection."
}
},
{
"@type": "Question",
"name": "Quels traitements existent pour l'activation virale ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les antiviraux, les immunomodulateurs et les soins de soutien sont utilisés."
}
},
{
"@type": "Question",
"name": "Les antibiotiques sont-ils efficaces contre les virus ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Non, les antibiotiques ne sont pas efficaces contre les infections virales."
}
},
{
"@type": "Question",
"name": "Les vaccins aident-ils à prévenir l'activation virale ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les vaccins peuvent prévenir certaines infections virales et leur activation."
}
},
{
"@type": "Question",
"name": "Comment les antiviraux agissent-ils ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Ils inhibent la réplication virale, réduisant ainsi la charge virale dans l'organisme."
}
},
{
"@type": "Question",
"name": "Les traitements sont-ils les mêmes pour tous les virus ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Non, chaque virus peut nécessiter un traitement spécifique adapté."
}
},
{
"@type": "Question",
"name": "Quelles sont les complications possibles d'une activation virale ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des complications comme la pneumonie, l'encéphalite ou des infections secondaires peuvent survenir."
}
},
{
"@type": "Question",
"name": "L'activation virale peut-elle entraîner des maladies chroniques ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certaines infections virales peuvent provoquer des maladies chroniques comme l'hépatite."
}
},
{
"@type": "Question",
"name": "Les complications sont-elles prévisibles ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines complications peuvent être prévisibles selon le virus et l'état de santé de l'hôte."
}
},
{
"@type": "Question",
"name": "Les enfants sont-ils plus à risque de complications ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les enfants peuvent être plus vulnérables à certaines complications virales."
}
},
{
"@type": "Question",
"name": "Comment gérer les complications d'une activation virale ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un suivi médical régulier et des traitements appropriés sont essentiels pour gérer les complications."
}
},
{
"@type": "Question",
"name": "Quels sont les facteurs de risque d'activation virale ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'immunodépression, le stress et les voyages fréquents augmentent le risque."
}
},
{
"@type": "Question",
"name": "L'âge influence-t-il le risque d'activation virale ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les personnes âgées et les jeunes enfants sont plus à risque."
}
},
{
"@type": "Question",
"name": "Les maladies chroniques augmentent-elles le risque ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des maladies comme le diabète ou le VIH augmentent le risque d'activation virale."
}
},
{
"@type": "Question",
"name": "Le mode de vie affecte-t-il le risque d'activation virale ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, un mode de vie sain peut réduire le risque d'activation virale."
}
},
{
"@type": "Question",
"name": "Le stress psychologique influence-t-il le risque ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le stress peut affaiblir le système immunitaire et augmenter le risque d'infection."
}
}
]
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}
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 07/03/2025
Contenu vérifié selon les dernières recommandations médicales
5 publications dans cette catégorie
Affiliations :
Institute of Molecular Biosciences, Mahidol University, Salaya 73170, Thailand.
Publications dans "Activation virale" :
4 publications dans cette catégorie
Affiliations :
Institute of Molecular Biosciences, Mahidol University, Salaya 73170, Thailand.
Publications dans "Activation virale" :
3 publications dans cette catégorie
Affiliations :
Department of Health and Nutrition, Faculty of Human Life Science, Shikoku University, Tokushima 771-1192, Japan.
Publications dans "Activation virale" :
3 publications dans cette catégorie
Affiliations :
Department of Applied Biological Chemistry, Graduate School of Agriculture, Osaka Metropolitan University, Sakai, Osaka 599-8531, Japan.
Publications dans "Activation virale" :
3 publications dans cette catégorie
Affiliations :
Institute of Molecular Biosciences, Mahidol University, Salaya 73170, Thailand.
Publications dans "Activation virale" :
3 publications dans cette catégorie
Affiliations :
Institute of Molecular Biosciences, Mahidol University, Salaya 73170, Thailand.
Publications dans "Activation virale" :
3 publications dans cette catégorie
Affiliations :
National Center for Genetic Engineering and Biotechnology (BIOTEC), National Science and Technology Development Agency, Pathum Thani, 12120, Thailand.
Publications dans "Activation virale" :
3 publications dans cette catégorie
Affiliations :
Laboratory of Molecular RNA Virology and Antiviral Strategies, Department of Microbiology, Yong Loo Lin School of Medicine, National University Health System, National University of Singapore, Singapore.
Publications dans "Activation virale" :
3 publications dans cette catégorie
Affiliations :
Laboratory of Molecular RNA Virology and Antiviral Strategies, Department of Microbiology, Yong Loo Lin School of Medicine, National University Health System, National University of Singapore, Singapore; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore. Electronic address: miccjh@nus.edu.sg.
Publications dans "Activation virale" :
2 publications dans cette catégorie
Affiliations :
Institute of Molecular Biosciences, Mahidol University, Salaya 73170, Thailand.
Publications dans "Activation virale" :
2 publications dans cette catégorie
Affiliations :
Department of Clinical and Biological Sciences, Laboratory of Molecular Virology and Antiviral Research, University of Turin, S. Luigi Gonzaga Hospital, Orbassano Turin, Italy.
Publications dans "Activation virale" :
2 publications dans cette catégorie
Affiliations :
Department of Clinical and Biological Sciences, Laboratory of Molecular Virology and Antiviral Research, University of Turin, S. Luigi Gonzaga Hospital, Orbassano Turin, Italy.
Publications dans "Activation virale" :
2 publications dans cette catégorie
Affiliations :
Department of Clinical and Biological Sciences, Laboratory of Molecular Virology and Antiviral Research, University of Turin, S. Luigi Gonzaga Hospital, Orbassano Turin, Italy.
Publications dans "Activation virale" :
2 publications dans cette catégorie
Affiliations :
Department of Clinical and Biological Sciences, Laboratory of Molecular Virology and Antiviral Research, University of Turin, S. Luigi Gonzaga Hospital, Orbassano Turin, Italy. Electronic address: david.lembo@unito.it.
Publications dans "Activation virale" :
2 publications dans cette catégorie
Affiliations :
Department of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh 11451, Kingdom of Saudi Arabia.
Publications dans "Activation virale" :
2 publications dans cette catégorie
Affiliations :
Department of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh 11451, Kingdom of Saudi Arabia.
Publications dans "Activation virale" :
2 publications dans cette catégorie
Affiliations :
Centre for Global Health Research, University of Edinburgh, Edinburgh, UK.
Publications dans "Activation virale" :
2 publications dans cette catégorie
Publications dans "Activation virale" :
2 publications dans cette catégorie
Affiliations :
College of Veterinary Medicine, Yangzhou University, Yangzhou, 225009, Jiangsu Province, PR China; Institute of Comparative Medicine, Yangzhou University, Yangzhou, 225009, Jiangsu Province, PR China.
Publications dans "Activation virale" :
2 publications dans cette catégorie
Affiliations :
Animal Infectious Disease Laboratory, College of Veterinary Medicine, Yangzhou University, Yangzhou, 225009, PR China; Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonosis, Yangzhou University, Yangzhou, 225009, Jiangsu Province, PR China.
Publications dans "Activation virale" :
Currently used stratification models in myeloma precursor disease as well as staging systems and response criteria in myeloma have limitations including failure to identify functionally high-risk myel...
B cell maturation antigen (BCMA) targeted immunotherapies have demonstrated remarkable clinical efficacy in multiple myeloma (MM). Here, we evaluated the BCMA expression in MM and other plasma cell dy...
From January 2018 to August 2021, 377 patients with PCDs were enrolled in this study, including 334 MM, 21 systemic light chain amyloidosis (AL), 5 POEMS syndrome, 14 monoclonal gammopathy of undeterm...
The patients with MM had a median BCMA positive rate of 88.55% (range, 0.2% - 99.9%) and median BCMA MFI of 1281 (range, 109 - 48586). While the median BCMA positive rate in other PCDs was 55.8% (6.2%...
In conclusion, BCMA has the potential to be a therapeutic target for other PCDs besides MM....
B-cell maturation antigen (BCMA) is a clinically validated target for multiple myeloma. T-cell engineered with chimeric antigen receptors (CARs) directed against BCMA have demonstrated robust therapeu...
The BAFF-APRIL system is crucial for the pathogenesis of systemic lupus erythematosus (SLE) by promoting B cell survival, differentiation and the maintenance of humoral autoimmunity. Here, we investig...
The considerable efficacy of B-cell maturation antigen-targeted chimeric antigen receptor (CAR)-T-cell therapy has been extensively demonstrated in the treatment of relapsed or refractory multiple mye...
This retrospective study reviewed 99 patients with relapsed or refractory multiple myeloma who underwent B-cell maturation antigen CAR-T-cell therapy at our institution between April 2018 and Septembe...
Among 93 evaluable patients, the incidence of prolonged hematologic toxicities was high after CAR-T-cell infusion, including 38.71% (36/93) of patients with prolonged neutropenia, 22.58% (21/93) with ...
Our findings improve the understanding of the impact of cytokines on hematopoietic functions, which could contribute to the mechanism investigation and exploration of potential intervention strategies...
Chimeric Antigen Receptor (CAR) T-cell is a breakthrough in cancer immunotherapy. The primary step of successful CAR T cell therapy is designing a specific single-chain fragment variable (scFv). This ...
Following the second generation of anti-BCMA CAR designing, the protein structure, function prediction, physicochemical complementarity at the ligand-receptor interface, and biding sites analysis of a...
In-silico results approved the suitable protein folding, perfect orientation, and correct locating of functional domains at the receptor-ligand binding site. The in-vitro results confirmed high expres...
In-silico studies before experimental assessments are crucial for state-of-art CAR designing. Highly activation and cytotoxicity of anti-BCMA CAR T-cell revealed that our CAR construct methodology wou...
Chimeric antigen receptor (CAR) T cell therapy targeting B cell maturation antigen (BCMA) has been approved for treating multiple myeloma (MM). Some clinical studies reported suboptimal outcomes, incl...
The aim of this study was to investigate serum levels of soluble B-cell maturation antigen (sBCMA) in childhood-onset systemic lupus erythematous (cSLE) patients with renal involvement, and to elucida...
116 cases of cSLE patients with renal involvement (84 females and 32 males; median age 11.6 (10.1, 12.9) years) hospitalized in Department of Pediatric Nephrology and Rheumatology, the First Affiliate...
Serum sBCMA levels were significantly increased in primary cSLE when compared with treated cSLE patients and HCs, whereas there was no significant difference between treated cSLE patients and HCs. Pat...
In cSLE patients with renal involvement, serum sBCMA levels correlated significantly with disease activity, immunological, and hematological parameters, but not with renal parameters. Our results sugg...
Infections are common in plasma cell cancer multiple myeloma (MM) due to disease-related immune deficiencies and cancer treatment. Myeloma cells express Toll-like receptors (TLRs), and TLR activation ...
While immunotherapies, such as CAR T therapy and bi-specific antibodies, have revolutionized the treatment of multiple myeloma (MM), patients with AL amyloidosis have been excluded from trials with th...