questionsmedicales.fr
Acides aminés, peptides et protéines
Protéines
Protéines membranaires
Récepteurs de surface cellulaire
Récepteurs immunologiques
Intégrines
Intégrines : Questions médicales fréquentes
Termes MeSH sélectionnés :
G2 Phase Cell Cycle Checkpoints
Diagnostic
5
Intégrines
Tests génétiques
Cytométrie en flux
Immunofluorescence
Imagerie moléculaire
Intégrines
Marqueurs tumoraux
Intégrines
Symptômes
5
Troubles de la coagulation
Intégrines
Cicatrisation
Migration cellulaire
Douleur articulaire
Arthrite
Maladies cutanées
Épidermolyse bulleuse
Prévention
5
Prévention
Mode de vie sain
Vaccination
Réponse immunitaire
Exercice physique
Santé cellulaire
Alimentation
Antioxydants
Traitements
5
Thérapies biologiques
Maladies auto-immunes
Médicaments anti-inflammatoires
Intégrines
Thérapie génique
Intégrines
Greffes d'organes
Rejet de greffe
Complications
5
Infections
Maladies auto-immunes
Maladies cardiovasculaires
Athérosclérose
Complications cutanées
Épidermolyse
Troubles neurologiques
Intégrines
Facteurs de risque
5
Facteurs de risque
Maladies auto-immunes
Vieillissement
Intégrines
Tabagisme
Santé cellulaire
Stress oxydatif
Intégrines
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"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les biopsies peuvent révéler des anomalies d'expression des intégrines dans les tissus."
}
},
{
"@type": "Question",
"name": "Peut-on détecter les intégrines par imagerie ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines techniques d'imagerie moléculaire peuvent visualiser l'expression des intégrines."
}
},
{
"@type": "Question",
"name": "Quels marqueurs sont associés aux intégrines ?",
"position": 5,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des marqueurs comme CD29 et CD49 peuvent être utilisés pour identifier les intégrines."
}
},
{
"@type": "Question",
"name": "Quels symptômes indiquent une anomalie des intégrines ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des problèmes d'adhésion cellulaire peuvent entraîner des inflammations et des infections récurrentes."
}
},
{
"@type": "Question",
"name": "Les troubles de la coagulation sont-ils liés aux intégrines ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des anomalies des intégrines peuvent provoquer des troubles de la coagulation sanguine."
}
},
{
"@type": "Question",
"name": "Comment les intégrines affectent-elles la cicatrisation ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les intégrines sont essentielles pour la migration cellulaire et la formation de nouveaux tissus lors de la cicatrisation."
}
},
{
"@type": "Question",
"name": "Les douleurs articulaires peuvent-elles être liées aux intégrines ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des dysfonctionnements des intégrines peuvent contribuer à des douleurs articulaires et à l'arthrite."
}
},
{
"@type": "Question",
"name": "Y a-t-il des symptômes cutanés associés aux intégrines ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des anomalies des intégrines peuvent entraîner des maladies cutanées comme l'épidermolyse bulleuse."
}
},
{
"@type": "Question",
"name": "Peut-on prévenir les troubles liés aux intégrines ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une alimentation équilibrée et un mode de vie sain peuvent aider à prévenir certains troubles liés aux intégrines."
}
},
{
"@type": "Question",
"name": "Les vaccinations influencent-elles les intégrines ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines vaccinations peuvent moduler l'expression des intégrines, influençant la réponse immunitaire."
}
},
{
"@type": "Question",
"name": "L'exercice physique affecte-t-il les intégrines ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'exercice régulier peut améliorer la fonction des intégrines et la santé cellulaire."
}
},
{
"@type": "Question",
"name": "Le stress a-t-il un impact sur les intégrines ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le stress chronique peut altérer l'expression des intégrines, affectant la santé immunitaire."
}
},
{
"@type": "Question",
"name": "Les habitudes alimentaires influencent-elles les intégrines ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une alimentation riche en antioxydants peut soutenir la fonction des intégrines et la santé cellulaire."
}
},
{
"@type": "Question",
"name": "Quels traitements ciblent les intégrines ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des thérapies biologiques, comme les inhibiteurs d'intégrines, sont utilisées pour traiter certaines maladies auto-immunes."
}
},
{
"@type": "Question",
"name": "Les médicaments anti-inflammatoires aident-ils les intégrines ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les anti-inflammatoires peuvent réduire l'inflammation liée aux dysfonctionnements des intégrines."
}
},
{
"@type": "Question",
"name": "La thérapie génique peut-elle corriger les anomalies des intégrines ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "La thérapie génique est une approche prometteuse pour corriger certaines anomalies des intégrines."
}
},
{
"@type": "Question",
"name": "Les greffes d'organes sont-elles affectées par les intégrines ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les intégrines jouent un rôle clé dans l'acceptation ou le rejet des greffes d'organes."
}
},
{
"@type": "Question",
"name": "Comment les intégrines sont-elles ciblées dans le cancer ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des traitements ciblant les intégrines peuvent inhiber la métastase et la progression tumorale."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir avec des anomalies des intégrines ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des complications incluent des infections récurrentes, des troubles de la coagulation et des maladies auto-immunes."
}
},
{
"@type": "Question",
"name": "Les anomalies des intégrines peuvent-elles causer des cancers ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des anomalies dans l'expression des intégrines sont associées à une augmentation du risque de cancer."
}
},
{
"@type": "Question",
"name": "Comment les intégrines affectent-elles la santé cardiovasculaire ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des dysfonctionnements des intégrines peuvent contribuer à des maladies cardiovasculaires et à l'athérosclérose."
}
},
{
"@type": "Question",
"name": "Les complications cutanées sont-elles fréquentes avec les intégrines ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des anomalies des intégrines peuvent entraîner des maladies cutanées graves comme l'épidermolyse."
}
},
{
"@type": "Question",
"name": "Les troubles neurologiques peuvent-ils être liés aux intégrines ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines études suggèrent un lien entre les anomalies des intégrines et des troubles neurologiques."
}
},
{
"@type": "Question",
"name": "Quels facteurs augmentent le risque de troubles des intégrines ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des facteurs génétiques, des infections chroniques et des maladies auto-immunes augmentent le risque."
}
},
{
"@type": "Question",
"name": "L'âge influence-t-il la fonction des intégrines ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le vieillissement peut altérer l'expression et la fonction des intégrines dans le corps."
}
},
{
"@type": "Question",
"name": "Le tabagisme affecte-t-il les intégrines ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le tabagisme peut perturber l'expression des intégrines et affecter la santé cellulaire."
}
},
{
"@type": "Question",
"name": "Le diabète influence-t-il les intégrines ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le diabète peut altérer la fonction des intégrines, augmentant le risque de complications."
}
},
{
"@type": "Question",
"name": "Le stress oxydatif affecte-t-il les intégrines ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le stress oxydatif peut endommager les intégrines et perturber leur fonction normale."
}
}
]
}
]
}
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 04/05/2025
Contenu vérifié selon les dernières recommandations médicales
3 publications dans cette catégorie
Affiliations :
Turku Bioscience Center, University of Turku and Åbo Akademi University, FIN-20520 Turku, Finland; Department of Biochemistry, University of Turku, FIN-20520 Turku, Finland. Electronic address: joivaska@utu.fi.
Publications dans "Intégrines" :
2 publications dans cette catégorie
Affiliations :
Shenzhen Jiake Biotechnology, Shenzhen, China.
Publications dans "Intégrines" :
2 publications dans cette catégorie
Affiliations :
Department of Cell Physiology and Metabolism, University of Geneva, Centre Médical Universitaire, Rue Michel-Servet 1, 1211 Geneva 4, Switzerland.
Zoological Institute, Cell- and Neurobiology, Karlsruhe Institute of Technology (KIT), Karlsruhe, Germany.
Publications dans "Intégrines" :
2 publications dans cette catégorie
Affiliations :
Faculty of Medicine and Health Technology, Tampere University, Arvo Ylpön katu 34, FI-33520 Tampere, Finland.
Fimlab Laboratories, Biokatu 4, FI-33520 Tampere, Finland.
Publications dans "Intégrines" :
2 publications dans cette catégorie
Affiliations :
Department of Cell Physiology and Metabolism, University of Geneva, Centre Médical Universitaire, Rue Michel-Servet 1, 1211 Geneva 4, Switzerland bernhard.wehrle-haller@unige.ch.
Publications dans "Intégrines" :
2 publications dans cette catégorie
Affiliations :
Department of Nuclear Medicine & Minnan PET Center, Xiamen Cancer Hospital, The First Affiliated Hospital of Xiamen University, China.
Publications dans "Intégrines" :
2 publications dans cette catégorie
Affiliations :
State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics & Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, Xiamen, China.
Publications dans "Intégrines" :
2 publications dans cette catégorie
Affiliations :
Department of Nuclear Medicine & Minnan PET Center, Xiamen Cancer Hospital, The First Affiliated Hospital of Xiamen University, China.
Publications dans "Intégrines" :
2 publications dans cette catégorie
Affiliations :
State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics & Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, Xiamen, China.
Publications dans "Intégrines" :
2 publications dans cette catégorie
Affiliations :
State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics & Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, Xiamen, China.
Publications dans "Intégrines" :
2 publications dans cette catégorie
Affiliations :
Zhong Yuan Academy of Biological Medicine, Liaocheng People's Hospital, No. 67 Dongchang West Road, Liaocheng 252000, China.
Publications dans "Intégrines" :
2 publications dans cette catégorie
Affiliations :
Department of Vascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Hubei Key Laboratory of Biological Targeted Therapy, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Publications dans "Intégrines" :
2 publications dans cette catégorie
Affiliations :
Department of Vascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Hubei Key Laboratory of Biological Targeted Therapy, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Publications dans "Intégrines" :
2 publications dans cette catégorie
Affiliations :
State Key Laboratory of Cell Biology, Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China.
Publications dans "Intégrines" :
2 publications dans cette catégorie
Affiliations :
State Key Laboratory of Cell Biology, Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China.
Publications dans "Intégrines" :
2 publications dans cette catégorie
Affiliations :
State Key Laboratory of Cell Biology, Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China.
Publications dans "Intégrines" :
2 publications dans cette catégorie
Affiliations :
Department of Orthopedics, Suzhou Ninth People's Hospital, Soochow University, Suzhou, Jiangsu, China.
Publications dans "Intégrines" :
2 publications dans cette catégorie
Affiliations :
School of Life Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou, Zhejiang, China.
State Key Laboratory of Cell Biology, Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China.
Publications dans "Intégrines" :
2 publications dans cette catégorie
Affiliations :
School of Life Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou, Zhejiang, China. yzeng@sibcb.ac.cn.
State Key Laboratory of Cell Biology, Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China. yzeng@sibcb.ac.cn.
Publications dans "Intégrines" :
2 publications dans cette catégorie
Affiliations :
School of Life Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou, Zhejiang, China. jfchen@sibcb.ac.cn.
State Key Laboratory of Cell Biology, Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China. jfchen@sibcb.ac.cn.
Publications dans "Intégrines" :
The North-eastern parts of India have immense therapeutic floras, Ottelia alismoides is an aquatic plant that has been in use for a long time in traditional medicine for treating diseases like cancer,...
The purpose of this study was to evaluate the apoptotic potential of acetone extract of O. alismoides (L.) Pers. (OA-AC) and to identify the compounds responsible for this effect, HRLC-MS-QTOF analysi...
A549 and A431 cells were treated with acetone extract of O. alismoides (OA-AC) at 24 h and 48 h exposure and cell cycle phase distribution was evaluated and also apoptosis induction activity was evalu...
The cell cycle phase distribution analysis in A549 and A431 cells at 24hrs exposure with 10 μg/mL and 25 μg/mL of OA-AC showed a potent arrest or blockage at the G2/M phase of the cell cycle with redu...
AO-EtBr staining of these cancer cells reveals that the death induced by OA-AC was apoptotic in nature with depolarization of mitochondrial membrane due to loss or damage of the mitochondrial membrane...
The average survival of patients with glioblastoma is 12-15 months. Therefore, finding a new treatment method is important, especially in cases that show resistance to treatment. Extremely low-frequen...
Hepatic iron overload is a universal phenomenon in patients with myelodysplastic syndromes (MDS) who undergo bone marrow transplantation and may experience the toxicity of peri- and post-bone marrow t...
The aim of this research is to understand the role of microRNA in cell cycle regulation especially on G2M Checkpoint from Luminal A samples Indonesian population. The profile results are used as bioma...
In this study, 5 (Formalin-Fixed Paraffin-Embedded) FFPE Luminal A tissues and 4 FFPE FAM samples were used. RNA was isolated from cancer tissue samples. Differential expression analysis of miRNA was ...
Based on 792 miRNAs detected on Nanostring nCounter, it was found that 60 miRNAs were upregulated and 6 miRNAs were downregulated. The 15 upregulated miRNAs analyzed show their role in the G2M Checkpo...
Significant differences in the expression of multiple miRNAs between Luminal A and FAM samples were observed. Furthermore, several of these miRNAs were found to modulate the G2M Checkpoint in Luminal ...
Cells respond to DNA double-strand breaks by initiating DSB repair and ensuring a cell cycle checkpoint. The primary responder to DSB repair is non-homologous end joining, which is an error-prone repa...
A collection of 2,3-arylpyridylindole derivatives were synthesized via the Larock heteroannulation and evaluated for their in vitro cytotoxic activity against A549 human lung cancer cells. Two derivat...
Crassolide, a cembranoid diterpene extracted from the soft coral...
Fibroblast growth factor 19 (FGF19) has appeared as a new possible avenue in the treatment of skeletal metabolic disorders. However, the role of FGF19 on cell cycle progression in skeletal system is p...
This study was focused on investigating the antiproliferative effects of chalcone hybrids in melanoma cancer cells. Among seven chalcone hybrids, the chalcone-acridine hybrid...
The extracellular signal-regulated kinase (ERK) 1 and 2 intracellular signaling pathways play key roles in a variety of cellular processes, such as proliferation and differentiation. Dysregulation of ...