Les troubles kinésines peuvent-ils entraîner des maladies graves ?
Oui, ils peuvent contribuer à des maladies neurodégénératives comme la maladie d'Alzheimer.
Maladies neurodégénérativesMaladie d'Alzheimer
#3
Y a-t-il des risques de paralysie avec des troubles kinésines ?
Oui, des troubles graves peuvent entraîner une paralysie ou une perte de mobilité.
ParalysiePerte de mobilité
#4
Les troubles kinésines peuvent-ils affecter la respiration ?
Oui, des complications peuvent affecter les muscles respiratoires et la fonction pulmonaire.
Fonction pulmonaireMuscles respiratoires
#5
Des troubles kinésines peuvent-ils causer des problèmes cardiaques ?
Oui, des dysfonctionnements peuvent affecter le cœur et la circulation sanguine.
Problèmes cardiaquesCirculation sanguine
Facteurs de risque
5
#1
Quels sont les facteurs de risque pour les troubles kinésines ?
Les facteurs génétiques, l'âge avancé et les maladies métaboliques augmentent le risque.
Facteurs génétiquesMaladies métaboliques
#2
Le mode de vie influence-t-il les troubles kinésines ?
Oui, un mode de vie sédentaire et une mauvaise alimentation peuvent aggraver les troubles.
Mode de vie sédentaireMauvaise alimentation
#3
Les antécédents familiaux jouent-ils un rôle ?
Oui, des antécédents familiaux de troubles neurologiques augmentent le risque.
Antécédents familiauxTroubles neurologiques
#4
Le stress est-il un facteur de risque pour les kinésines ?
Oui, le stress chronique peut affecter la fonction des kinésines et la santé cellulaire.
Stress chroniqueSanté cellulaire
#5
L'exposition à des toxines influence-t-elle les kinésines ?
Oui, l'exposition à certaines toxines peut nuire à la fonction des kinésines.
Exposition aux toxinesFonction des kinésines
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"name": "Comment diagnostiquer une dysfonction des kinésines ?",
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"text": "Des tests génétiques et des analyses de protéines peuvent aider à diagnostiquer."
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"@type": "Question",
"name": "Quels examens sont utilisés pour évaluer les kinésines ?",
"position": 2,
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"position": 3,
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"text": "Oui, des tests sanguins peuvent révéler des niveaux anormaux de protéines motrices."
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"@type": "Question",
"name": "Quels symptômes indiquent un problème avec les kinésines ?",
"position": 4,
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"@type": "Question",
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"position": 8,
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"@type": "Question",
"name": "Les troubles de la vision peuvent-ils être liés aux kinésines ?",
"position": 9,
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"@type": "Question",
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"name": "L'exercice régulier aide-t-il à la santé des kinésines ?",
"position": 12,
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"position": 13,
"acceptedAnswer": {
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"text": "Oui, ils permettent de détecter précocement des anomalies kinésines."
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"position": 14,
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"@type": "Question",
"name": "Le stress peut-il affecter les kinésines ?",
"position": 15,
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"name": "Quels traitements existent pour les troubles kinésines ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "La thérapie génique et les médicaments ciblés sont des options de traitement."
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{
"@type": "Question",
"name": "La physiothérapie aide-t-elle en cas de dysfonction kinésines ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, la physiothérapie peut améliorer la force et la coordination musculaire."
}
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{
"@type": "Question",
"name": "Des suppléments nutritionnels peuvent-ils aider ?",
"position": 18,
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"@type": "Question",
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"position": 19,
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"text": "Oui, ils peuvent réduire l'inflammation et améliorer la fonction musculaire."
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"@type": "Question",
"name": "La recherche sur les kinésines progresse-t-elle ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des études sont en cours pour développer de nouveaux traitements ciblés."
}
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{
"@type": "Question",
"name": "Quelles complications peuvent survenir avec des troubles kinésines ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des complications neurologiques, musculaires et métaboliques peuvent se développer."
}
},
{
"@type": "Question",
"name": "Les troubles kinésines peuvent-ils entraîner des maladies graves ?",
"position": 22,
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"@type": "Answer",
"text": "Oui, ils peuvent contribuer à des maladies neurodégénératives comme la maladie d'Alzheimer."
}
},
{
"@type": "Question",
"name": "Y a-t-il des risques de paralysie avec des troubles kinésines ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des troubles graves peuvent entraîner une paralysie ou une perte de mobilité."
}
},
{
"@type": "Question",
"name": "Les troubles kinésines peuvent-ils affecter la respiration ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des complications peuvent affecter les muscles respiratoires et la fonction pulmonaire."
}
},
{
"@type": "Question",
"name": "Des troubles kinésines peuvent-ils causer des problèmes cardiaques ?",
"position": 25,
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"name": "Quels sont les facteurs de risque pour les troubles kinésines ?",
"position": 26,
"acceptedAnswer": {
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"text": "Les facteurs génétiques, l'âge avancé et les maladies métaboliques augmentent le risque."
}
},
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"@type": "Question",
"name": "Le mode de vie influence-t-il les troubles kinésines ?",
"position": 27,
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"@type": "Answer",
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"@type": "Question",
"name": "Les antécédents familiaux jouent-ils un rôle ?",
"position": 28,
"acceptedAnswer": {
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"text": "Oui, des antécédents familiaux de troubles neurologiques augmentent le risque."
}
},
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"name": "Le stress est-il un facteur de risque pour les kinésines ?",
"position": 29,
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}
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"@type": "Question",
"name": "L'exposition à des toxines influence-t-elle les kinésines ?",
"position": 30,
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"@type": "Answer",
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Department of Biophysics, University of Michigan, Ann Arbor, Michigan; Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, Michigan.
Faculty of Science, Hokkaido University, Sapporo, 060-0810, Japan; Graduate School of Chemical Sciences and Engineering, Hokkaido University, Sapporo, 060-0810, Japan.
Faculty of Science, Hokkaido University, Sapporo, 060-0810, Japan; Graduate School of Chemical Sciences and Engineering, Hokkaido University, Sapporo, 060-0810, Japan. Electronic address: kakugo@sci.hokudai.ac.jp.
Little information is available about the clinical and pathologic characteristics of local recurrence (LR) after nipple-sparing mastectomy according to the locations of LR....
This study classified 99 patients into the following two groups according to the location of LR after nipple-sparing mastectomy: nipple-areolar recurrence (NAR) group and other locations of LR (oLR) g...
For about half of the patients (44.4 %) with NAR, the primary cancer was estrogen receptor (ER)-negative and human epidermal growth factor receptor 2 (HER2)-positive. Conversely, in most of the patien...
This multi-institutional retrospective study demonstrated that the features of NAR, such as the characteristics of the primary and recurrent tumors and the prognostic factors after LR resection, were ...
Despite advances in perioperative management, recurrence after curative pancreatectomy is a critical issue in the treatment of pancreatic ductal adenocarcinoma (PDAC). The significance of local therap...
We reviewed the medical records of patients with PDAC who underwent curative resection at our institution between January 2009 and December 2019. We examined the patterns of relapse and assessed the c...
A total of 246 patients with PDAC who underwent R0 or R1 resection were included in this study. The 3-year overall survival (OS) rate was 39.8%, and the 1-year recurrence-free survival rate was 51.2% ...
Our results suggest that a multimodal approach may improve the clinical outcomes of patients with recurrent PDAC....
Skin cancer may recur at or around the surgical site despite wide excisions. Prompt clinical and sonographic detection of local recurrence is important since subjects with relapsing melanomas or nonme...
Pathological factors that influence and predict survival following pelvic exenteration (PE) for locally advanced (LARC) or locally recurrent rectal cancer (LRRC), especially LRRC, remain poorly unders...
A retrospective cohort study was performed for all patients undergoing a curative PE for LARC or LRRC between 2008 and 2021 at a tertiary referral UK specialist colorectal hospital. Cox regression ana...
388 patients were included in the analysis with 256 resections for LARC and 132 for LRRC. 62.4% of patients were male with a median age of 59 years (IQR 49-67). 247 (64%) partial pelvic exenterations ...
A positive resection margin and poorly differentiated tumours are significant negative prognostic markers for survival and recurrence in LARC. The results of this study support the need to look for al...
Using CODA, a technique for three-dimensional reconstruction of large tissues, Kiemen et al. report observation of a microscopic focus of pancreatic cancer found in the vasculature of grossly normal h...
The initial approach to the treatment of desmoid tumors has changed from surgical resection to watchful waiting. However, surgery is still sometimes considered for some patients, and it is likely that...
We sought to explore whether a combined molecular and clinical prognostic model for relapse in patients with desmoid tumors treated with surgery would allow us to identify patients who might do well w...
This was a retrospective, single-center study of 107 patients with desmoid tumors who were surgically treated between January 1980 and December 2015, with a median follow-up of 106 months (range 7 to ...
The multivariable analysis showed that S45F mutations (hazard ratio 5.25 [95% confidence interval 2.27 to 12.15]; p < 0.001) and tumor in the extremities (HR 3.15 [95% CI 1.35 to 7.33]; p = 0.008) wer...
CTNNB1 S45F mutations combined with other clinical variables are a potential prognostic biomarker associated with the risk of relapse in patients with desmoid tumors. The developed nomogram is simple ...
Level III, therapeutic study....
A first local recurrence is common after resection or radiotherapy for brain metastasis (BM). However, patients with BMs can develop multiple local recurrences over time. Published data on second loca...
Patients were identified from a database at Brigham and Women's Hospital in Boston. Hazard ratios and 95% confidence intervals for predictors of a second local recurrence were computed using a Cox pro...
Of 170 identified surgically treated first locally recurrent lesions, 74 (43.5%) progressed to second locally recurrent lesions at a median of 7 months after craniotomy. Subtotal resection of the firs...
A second local recurrence occurred after 43.5% of craniotomies for first recurrent lesions. Subtotal resection and infratentorial location were the strongest risk factors for worse second local recurr...
The current study was undertaken to provide more detailed prognostic models for early prediction of local recurrences and local recurrence free survival (RFS) using different radiologic and pathologic...
One hundred patients with locally advanced rectal carcinomas decided to receive neoadjuvant CRT were retrospectively recruited, Hazard ratios (HR) were determined in the two cox regression models and ...
HR of 1st group of models: T+N, T+N+G, T+N+G+S, T+N+G+S+PNI, and T+N+G+S+PNI+R were summated and categorized into scores, these scores were significantly correlated with the risk of recurrence (Somer'...
We propose that the addition of biologic factors to staging of rectal cancer provide precise stratification and association with local recurrences in patients received preoperative CRT....
This study aims to identify prognostic factors and define the best extent of surgery for optimizing treatment of local recurrence (LR) following colorectal cancer (CRC)....
An institutional database of consecutive patients who underwent radical resection (R0/R1) of LR following CRC was analyzed prospectively from 2010 to 2021 at one tertiary cancer center....
In this study, 75 patients were included with LR following CRC and analyzed. Patients were categorized as compartmental resections (CompRe) (n = 47) if all adjacent organs were systematically removed,...
Complete compartmental surgery is safe and improves local control. Optimal LR resection needs to remove all contiguous organs, with or without tumor involvement....
RET-fused mesenchymal neoplasms mostly affect the soft tissue of paediatric patients. Given their responsiveness to selective RET inhibitors, it remains critical to identify those extraordinary cases ...
Clinicopathological features were assessed and partner agnostic targeted next-generation sequencing on clinically validated platforms were performed. The patients were 18, 53, and 55 years old and inc...
Our study expands the clinicopathological and genetic spectrum of mesenchymal neoplasms associated with RET fusions....
