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Facteurs biologiques
Protéines et peptides de signalisation intercellulaire
Cytokines
Chimiokines
Chimiokines CXC
Chimiokines CXC : Questions médicales fréquentes
Termes MeSH sélectionnés :
Diagnostic
5
Chimiokines
Tests de laboratoire
Maladies auto-immunes
Inflammation
Biopsie
Immunohistochimie
Symptômes
5
Système nerveux
Inflammation cérébrale
Psoriasis
Maladies cutanées
Maladies inflammatoires de l'intestin
Symptômes digestifs
Prévention
5
Hygiène de vie
Gestion du stress
Alimentation
Antioxydants
Exercice physique
Santé immunitaire
Stress chronique
Inflammation
Traitements
5
Thérapies biologiques
Inhibiteurs
Corticostéroïdes
Inflammation
Traitements anti-inflammatoires
Symptômes inflammatoires
Essais cliniques
Traitements
Complications
5
Maladies auto-immunes
Infections chroniques
Cicatrisation
Inflammation
Maladies cardiovasculaires
Risque
Sclérose en plaques
Alzheimer
Facteurs de risque
5
Infections
Expression génique
Vieillissement
Inflammation
Diabète
Maladies métaboliques
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"@type": "Question",
"name": "Comment diagnostiquer une dysrégulation des chimiokines CXC ?",
"position": 1,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des tests sanguins et des analyses de cytokines peuvent aider à évaluer les niveaux de chimiokines."
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"@type": "Question",
"name": "Quels tests sont utilisés pour mesurer les chimiokines CXC ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les dosages ELISA et les tests multiplex sont couramment utilisés pour mesurer les chimiokines."
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"@type": "Question",
"name": "Les chimiokines CXC sont-elles liées à des maladies spécifiques ?",
"position": 3,
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"@type": "Question",
"name": "Peut-on détecter les chimiokines CXC dans les biopsies ?",
"position": 4,
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"@type": "Answer",
"text": "Oui, les chimiokines peuvent être détectées dans les tissus par immunohistochimie."
}
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"@type": "Question",
"name": "Les niveaux de chimiokines CXC varient-ils selon l'âge ?",
"position": 5,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les niveaux de chimiokines peuvent varier avec l'âge et l'état de santé général."
}
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"@type": "Question",
"name": "Quels symptômes sont associés à une surproduction de chimiokines CXC ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les symptômes incluent inflammation, douleur, fatigue et troubles immunitaires."
}
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"@type": "Question",
"name": "Les chimiokines CXC peuvent-elles causer des symptômes respiratoires ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elles sont impliquées dans des maladies respiratoires comme l'asthme et la BPCO."
}
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"@type": "Question",
"name": "Comment les chimiokines CXC affectent-elles le système nerveux ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elles peuvent contribuer à des troubles neurologiques en modulant l'inflammation cérébrale."
}
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{
"@type": "Question",
"name": "Les chimiokines CXC sont-elles liées à des symptômes cutanés ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elles peuvent être impliquées dans des maladies cutanées inflammatoires comme le psoriasis."
}
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"@type": "Question",
"name": "Peut-on observer des symptômes digestifs liés aux chimiokines CXC ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elles peuvent jouer un rôle dans des maladies inflammatoires de l'intestin."
}
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"@type": "Question",
"name": "Peut-on prévenir les maladies liées aux chimiokines CXC ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une bonne hygiène de vie et la gestion du stress peuvent aider à prévenir certaines maladies."
}
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"@type": "Question",
"name": "L'alimentation influence-t-elle les chimiokines CXC ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, une alimentation riche en antioxydants peut réduire l'inflammation et les chimiokines."
}
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"@type": "Question",
"name": "L'exercice physique affecte-t-il les niveaux de chimiokines CXC ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'exercice régulier peut moduler les niveaux de chimiokines et améliorer la santé immunitaire."
}
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"@type": "Question",
"name": "Le tabagisme influence-t-il les chimiokines CXC ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le tabagisme augmente les niveaux de chimiokines et contribue à l'inflammation."
}
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"@type": "Question",
"name": "Le stress chronique affecte-t-il les chimiokines CXC ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le stress chronique peut augmenter l'expression des chimiokines et aggraver l'inflammation."
}
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{
"@type": "Question",
"name": "Quels traitements ciblent les chimiokines CXC ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des thérapies biologiques et des inhibiteurs de chimiokines sont en développement."
}
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"@type": "Question",
"name": "Les corticostéroïdes affectent-ils les chimiokines CXC ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les corticostéroïdes peuvent réduire l'expression des chimiokines CXC dans l'inflammation."
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"@type": "Question",
"name": "Comment les inhibiteurs de chimiokines CXC fonctionnent-ils ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Ils bloquent les récepteurs des chimiokines, réduisant ainsi l'inflammation et la migration cellulaire."
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"@type": "Question",
"name": "Les traitements anti-inflammatoires influencent-ils les chimiokines CXC ?",
"position": 19,
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"text": "Oui, ils peuvent moduler les niveaux de chimiokines et améliorer les symptômes inflammatoires."
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"@type": "Question",
"name": "Y a-t-il des essais cliniques sur les chimiokines CXC ?",
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"text": "Oui, plusieurs essais cliniques évaluent des traitements ciblant les chimiokines CXC."
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"text": "Des complications incluent des maladies auto-immunes, des infections chroniques et des cancers."
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"@type": "Question",
"name": "Les chimiokines CXC sont-elles impliquées dans le cancer ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elles peuvent favoriser la progression tumorale et la métastase dans certains cancers."
}
},
{
"@type": "Question",
"name": "Comment les chimiokines CXC affectent-elles la cicatrisation des plaies ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une surproduction peut retarder la cicatrisation en exacerbant l'inflammation."
}
},
{
"@type": "Question",
"name": "Les maladies cardiovasculaires sont-elles liées aux chimiokines CXC ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des niveaux élevés de chimiokines sont associés à un risque accru de maladies cardiovasculaires."
}
},
{
"@type": "Question",
"name": "Les chimiokines CXC peuvent-elles causer des troubles neurologiques ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elles sont impliquées dans des troubles comme la sclérose en plaques et l'Alzheimer."
}
},
{
"@type": "Question",
"name": "Quels facteurs de risque augmentent les niveaux de chimiokines CXC ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'obésité, le tabagisme et le stress chronique sont des facteurs de risque connus."
}
},
{
"@type": "Question",
"name": "Les infections peuvent-elles influencer les chimiokines CXC ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les infections aiguës et chroniques peuvent augmenter l'expression des chimiokines."
}
},
{
"@type": "Question",
"name": "L'exposition à des polluants affecte-t-elle les chimiokines CXC ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'exposition à des polluants environnementaux peut augmenter les niveaux de chimiokines."
}
},
{
"@type": "Question",
"name": "Le vieillissement influence-t-il les chimiokines CXC ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le vieillissement peut entraîner une augmentation des niveaux de chimiokines et de l'inflammation."
}
},
{
"@type": "Question",
"name": "Les maladies métaboliques sont-elles liées aux chimiokines CXC ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des maladies comme le diabète peuvent augmenter les niveaux de chimiokines et l'inflammation."
}
}
]
}
]
}
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
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Dermatologic surgeons are faced with a dilemma when counseling actively smoking patients who require dermatologic surgery: recommend total cessation of all nicotine that is associated with extremely h...
To determine the safety of NRT in dermatologic surgery....
PubMed was queried: [(nicotine OR electronic cigarettes) AND (flap OR wound healing)]....
Smoking tobacco is detrimental to wound healing, supported by ample evidence (1A). Perioperative smoking cessation reduces risk (1B). Basic science demonstrates both a benefit and detriment of nicotin...
Dermatologists should consider recommending nicotine replacement for smokers in the perioperative period. Evidence is lacking to determine safety in flaps. It is presumed based on animal studies that ...
Although nicotine from cigarettes is delivered in puff-sized amounts, most preclinical and human intravenous (IV) nicotine studies have used bolus or continuous infusions....
To determine the feasibility of a pulsed-nicotine infusion model in smokers....
Following overnight abstinence, 12 adult smokers underwent 5 laboratory sessions. Using a crossover design, in each session, participants were assigned to 1 of 5 conditions: (1) high/fast: 1.0 mg nico...
Both the high/fast and high/slow conditions were associated with greater "head rush" and "high" (p < 0.05). The high/fast condition also provided greater suppression of urges to smoke and nicotine wit...
These findings demonstrate the feasibility of pulsed-nicotine infusions to model nicotine delivery by smoking. This model could inform future studies testing novel smoking cessation therapies and toba...
Nicotine exhibits obvious heterosis, which can be used to create Nicotiana tabacum L. (tobacco) varieties with varying nicotine content. However, the reasons for the formation of nicotine heterosis an...
Developmental periods such as gestation and adolescence have enhanced plasticity leaving the brain vulnerable to harmful effects from nicotine use. Proper brain maturation and circuit organization is ...
The introduction of synthetic nicotine by the tobacco industry, also promoted as tobacco-free nicotine, presented new challenges for analytical chemists working in tobacco regulatory science to develo...
Sociodemographic differences in e-cigarette use have been documented; however, disparities in use of specific e-cigarette types with various ingredients have yet to be thoroughly investigated. This st...
Data were drawn from a 2021 national cross-sectional survey of adolescents, young adults, and adults (N = 6131, ages 13-40 years old). Participants reported ever and past-30-day-use of (1) disposable ...
Females born between 1996 and 2008 reported higher rates of past-30-day disposable e-cigarette use relative to males (females 26.4%; males 22.4%). Compared to their heterosexual counterparts, LGBTQ+ p...
Findings highlight sociodemographic disparities in e-cigarette use, though differences varied based on e-cigarette device type and participant birth year category. Tailored preventive efforts may be n...
This study examines the demographic factors associated with youths' first product tried (i.e., cigarettes, e-cigarettes, cigars, hookah, or smokeless tobacco). This study also evaluates whether the fi...
Electronic nicotine delivery systems (ENDS) are used by smokers seeking to reduce combustible cigarette (CC) use, but the role of nicotine replacement vs. behavioral and sensory factors is still poorl...
To assess the effects on smoking behavior of using nicotine vs. placebo ENDS in smokers using nicotine vs. placebo patches....
Ninety-four daily smokers were enrolled in a study that randomly assigned them to receive ENDS with nicotine vs. without nicotine and skin patches with vs. without nicotine. Smoking reduction and cess...
The use of nicotine in ENDS led to significant reductions in smoking (ENDS nicotine vs. placebo difference in CO change = -9.2 ppm; 90% CI (-1.5 ppm, -16.9 ppm)) and was highly correlated with reducti...
The presence of nicotine in ENDS was associated with a large reduction in smoking. Additional studies will be needed to determine whether there may be additive effects of nicotine ENDS and nicotine pa...
Smokers are more likely to undergo postoperative complications after plastic surgeries. Our main purpose was to update nicotine's effects after plastic surgeries and assess whether nicotine-replacemen...
We set up a literature review including 40 documents from 1986 to 2020 available on Pubmed....
Nicotine has undeniable detrimental effects on patients undergoing plastic surgeries like cutaneous necrosis, skin flap failure and surgical site infection. Nevertheless, this toxicity seems to depend...
It seems more appropriate to suggest stopping all nicotine intake before and after plastic surgery. However, if strict cessation is not achievable, it appears preferable to use nicotine replacement th...
Electronic vaping devices are being used to consume nicotine and non-nicotine psychoactive drugs. We aimed to determine the pattern and prevalence of using vaping devices for nicotine and/or non-nicot...
An online cross-sectional survey PARTICIPANTS: A convenience sample of adults (aged ≥18 years) in the UK....
The primary outcome was prevalence of current use (within the last 30 days) of a vaping device to administer either nicotine or 18 types of non-nicotine drugs. We additionally evaluated reasons for on...
We recruited 4027 participants of whom 1637 (40.7%) had ever used an electronic vaping device; 1495 (37.1%) had ever vaped nicotine and 593 (14.7%) had ever vaped a non-nicotine drug. Overall, 574 (14...
A non-trivial number of people report current use and ever use of an electronic vaping device for non-nicotine drug administration. As vaping technology advances and drug consumption changes, understa...
