Myopathie à axe central : Questions médicales fréquentes
Nom anglais: Myopathy, Central Core
Descriptor UI:D020512
Tree Number:C10.668.491.550.300
Termes MeSH sélectionnés :
Pharmacists
Questions fréquentes et termes MeSH associés
Diagnostic
5
#1
Comment diagnostique-t-on la myopathie à axe central ?
Le diagnostic repose sur l'examen clinique, l'électromyogramme et la biopsie musculaire.
MyopathieBiopsie musculaire
#2
Quels tests génétiques sont utilisés ?
Des tests génétiques peuvent identifier des mutations dans le gène RYR1, associé à cette myopathie.
Tests génétiquesRYR1
#3
Quels signes cliniques sont observés ?
On observe souvent une faiblesse musculaire proximale et des anomalies dans les biopsies musculaires.
Faiblesse musculaireBiopsie musculaire
#4
L'IRM est-elle utile pour le diagnostic ?
Oui, l'IRM peut montrer des anomalies musculaires caractéristiques de la myopathie à axe central.
IRMMyopathie
#5
Quel rôle joue l'historique familial ?
Un historique familial de myopathies peut orienter le diagnostic vers une origine génétique.
Antécédents familiauxMyopathie
Symptômes
5
#1
Quels sont les principaux symptômes ?
Les symptômes incluent faiblesse musculaire, fatigue et parfois des douleurs musculaires.
SymptômesFaiblesse musculaire
#2
La myopathie affecte-t-elle tous les muscles ?
Elle touche principalement les muscles proximaux, comme ceux des hanches et des épaules.
Muscles proximauxMyopathie
#3
Y a-t-il des symptômes respiratoires ?
Dans certains cas, la faiblesse musculaire peut affecter les muscles respiratoires.
Symptômes respiratoiresMyopathie
#4
Les symptômes varient-ils selon l'âge ?
Oui, les symptômes peuvent apparaître dès l'enfance ou à l'âge adulte, selon les cas.
Âge d'apparitionMyopathie
#5
Des troubles de la marche sont-ils fréquents ?
Oui, la faiblesse musculaire peut entraîner des difficultés à marcher ou à se lever.
Troubles de la marcheFaiblesse musculaire
Prévention
5
#1
Peut-on prévenir la myopathie à axe central ?
Étant génétique, il n'existe pas de prévention, mais un diagnostic précoce aide à la gestion.
PréventionDiagnostic précoce
#2
Le dépistage est-il recommandé ?
Le dépistage génétique peut être conseillé pour les familles à risque de transmission.
DépistageTransmission génétique
#3
Des conseils de vie peuvent-ils aider ?
Des conseils sur l'exercice et la nutrition peuvent améliorer la qualité de vie des patients.
Conseils de vieQualité de vie
#4
Les activités physiques sont-elles bénéfiques ?
Des activités adaptées peuvent aider à maintenir la force musculaire et la mobilité.
Activités physiquesMobilité
#5
Les consultations régulières sont-elles nécessaires ?
Oui, des suivis réguliers permettent d'ajuster les traitements et surveiller l'évolution.
ConsultationsSuivi médical
Traitements
5
#1
Quels traitements sont disponibles ?
Il n'existe pas de traitement curatif, mais la physiothérapie aide à maintenir la force musculaire.
PhysiothérapieTraitement
#2
Les médicaments sont-ils efficaces ?
Des médicaments peuvent être prescrits pour gérer les symptômes, mais leur efficacité varie.
MédicamentsSymptômes
#3
La chirurgie est-elle une option ?
La chirurgie n'est généralement pas indiquée, sauf pour des complications spécifiques.
ChirurgieComplications
#4
Comment la rééducation aide-t-elle ?
La rééducation physique aide à améliorer la fonction musculaire et la qualité de vie.
RééducationQualité de vie
#5
Y a-t-il des traitements expérimentaux ?
Des essais cliniques explorent des thérapies géniques et des traitements ciblés.
Thérapie géniqueEssais cliniques
Complications
5
#1
Quelles complications peuvent survenir ?
Les complications incluent des problèmes respiratoires et des déformations musculo-squelettiques.
ComplicationsDéformations musculo-squelettiques
#2
La myopathie peut-elle affecter la vie quotidienne ?
Oui, la faiblesse musculaire peut limiter les activités quotidiennes et l'autonomie.
Vie quotidienneAutonomie
#3
Y a-t-il un risque de cardiomyopathie ?
Certaines formes de myopathie peuvent être associées à des problèmes cardiaques.
CardiomyopathieMyopathie
#4
Les infections sont-elles plus fréquentes ?
Les infections peuvent survenir en raison de la faiblesse musculaire et de l'immobilité.
InfectionsImmobilité
#5
Comment gérer les complications ?
Une prise en charge multidisciplinaire est essentielle pour gérer les complications.
Prise en chargeMultidisciplinaire
Facteurs de risque
5
#1
Quels sont les facteurs de risque génétiques ?
Les antécédents familiaux de myopathies augmentent le risque de développer cette maladie.
Facteurs de risqueAntécédents familiaux
#2
L'âge est-il un facteur de risque ?
L'âge d'apparition peut varier, mais les symptômes se manifestent souvent dans l'enfance.
ÂgeMyopathie
#3
Le sexe influence-t-il le risque ?
Les myopathies peuvent affecter les deux sexes, mais certaines formes sont plus fréquentes chez les hommes.
SexeMyopathie
#4
Des facteurs environnementaux jouent-ils un rôle ?
Actuellement, les facteurs environnementaux ne sont pas clairement établis comme des risques.
Facteurs environnementauxMyopathie
#5
Les maladies associées augmentent-elles le risque ?
Certaines maladies auto-immunes peuvent coexister avec la myopathie, mais leur lien n'est pas direct.
Maladies auto-immunesMyopathie
{
"@context": "https://schema.org",
"@graph": [
{
"@type": "MedicalWebPage",
"name": "Myopathie à axe central : Questions médicales les plus fréquentes",
"headline": "Myopathie à axe central : Comprendre les symptômes, diagnostics et traitements",
"description": "Guide complet et accessible sur les Myopathie à axe central : explications, diagnostics, traitements et prévention. Information médicale validée destinée aux patients.",
"datePublished": "2024-06-04",
"dateModified": "2025-03-01",
"inLanguage": "fr",
"medicalAudience": [
{
"@type": "MedicalAudience",
"name": "Grand public",
"audienceType": "Patient",
"healthCondition": {
"@type": "MedicalCondition",
"name": "Myopathie à axe central"
},
"suggestedMinAge": 18,
"suggestedGender": "unisex"
},
{
"@type": "MedicalAudience",
"name": "Médecins",
"audienceType": "Physician",
"geographicArea": {
"@type": "AdministrativeArea",
"name": "France"
}
},
{
"@type": "MedicalAudience",
"name": "Chercheurs",
"audienceType": "Researcher",
"geographicArea": {
"@type": "AdministrativeArea",
"name": "International"
}
}
],
"reviewedBy": {
"@type": "Person",
"name": "Dr Olivier Menir",
"jobTitle": "Expert en Médecine",
"description": "Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale",
"url": "/static/pages/docteur-olivier-menir.html",
"alumniOf": {
"@type": "EducationalOrganization",
"name": "Université Paris Descartes"
}
},
"isPartOf": {
"@type": "MedicalWebPage",
"name": "Myopathies congénitales structurales",
"url": "https://questionsmedicales.fr/mesh/D020914",
"about": {
"@type": "MedicalCondition",
"name": "Myopathies congénitales structurales",
"code": {
"@type": "MedicalCode",
"code": "D020914",
"codingSystem": "MeSH"
},
"identifier": {
"@type": "PropertyValue",
"propertyID": "MeSH Tree",
"value": "C10.668.491.550"
}
}
},
"about": {
"@type": "MedicalCondition",
"name": "Myopathie à axe central",
"alternateName": "Myopathy, Central Core",
"code": {
"@type": "MedicalCode",
"code": "D020512",
"codingSystem": "MeSH"
}
},
"author": [
{
"@type": "Person",
"name": "David Lacomis",
"url": "https://questionsmedicales.fr/author/David%20Lacomis",
"affiliation": {
"@type": "Organization",
"name": "Departments of Neurology and Pathology (Neuropathology), University of Pittsburgh School of Medicine, Pittsburgh, PA."
}
},
{
"@type": "Person",
"name": "Ichizo Nishino",
"url": "https://questionsmedicales.fr/author/Ichizo%20Nishino",
"affiliation": {
"@type": "Organization",
"name": "Department of Neuromuscular Research, National Center of Neurology and Psychiatry (NCNP), National Institute of Neuroscience, 4-1-1 Ogawahigashi, Tokyo 187-8502, Japan; Medical Genome Center, NCNP, Tokyo, Kodaira, Japan. Electronic address: nishino@ncnp.go.jp."
}
},
{
"@type": "Person",
"name": "John Rendu",
"url": "https://questionsmedicales.fr/author/John%20Rendu",
"affiliation": {
"@type": "Organization",
"name": "INSERM, GIN-U1216, CHU Grenoble Alpes, Grenoble Institut Neurosciences, University Grenoble Alpes, Bat EJ Safra, Chemin Fortuné Ferrini, La Tronche, Grenoble, France."
}
},
{
"@type": "Person",
"name": "Julien Fauré",
"url": "https://questionsmedicales.fr/author/Julien%20Faur%C3%A9",
"affiliation": {
"@type": "Organization",
"name": "INSERM, GIN-U1216, CHU Grenoble Alpes, Grenoble Institut Neurosciences, University Grenoble Alpes, Bat EJ Safra, Chemin Fortuné Ferrini, La Tronche, Grenoble, France."
}
},
{
"@type": "Person",
"name": "Satoru Noguchi",
"url": "https://questionsmedicales.fr/author/Satoru%20Noguchi",
"affiliation": {
"@type": "Organization",
"name": "Department of Neuromuscular Research, National Institute of Neuroscience, National Center of Neurology and Psychiatry, 187-8502 Tokyo, Japan; Department of Genome Medicine Development, Medical Genome Center, National Center of Neurology and Psychiatry, 187-8551 Tokyo, Japan."
}
}
],
"citation": [
{
"@type": "ScholarlyArticle",
"name": "Relationship between assertiveness in community pharmacists and pharmacist-initiated prescription changes.",
"datePublished": "2023-06-30",
"url": "https://questionsmedicales.fr/article/37419769",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1016/j.sapharm.2023.06.006"
}
},
{
"@type": "ScholarlyArticle",
"name": "Specialist pharmacist consultations with cancer patients in a pharmacist-led anticancer clinic.",
"datePublished": "2022-11-13",
"url": "https://questionsmedicales.fr/article/36373173",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1111/ajco.13887"
}
},
{
"@type": "ScholarlyArticle",
"name": "GPs' and pharmacists' views of integrating pharmacists into general practices: a qualitative study.",
"datePublished": "2023-05-25",
"url": "https://questionsmedicales.fr/article/37230784",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.3399/BJGP.2022.0518"
}
},
{
"@type": "ScholarlyArticle",
"name": "Pharmacist direct dispensing of mifepristone for medication abortion in Canada: a survey of community pharmacists.",
"datePublished": "2022-10-07",
"url": "https://questionsmedicales.fr/article/36207038",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1136/bmjopen-2022-063370"
}
},
{
"@type": "ScholarlyArticle",
"name": "Pharmacist prescribing: a review of perceptions and attitudes of patients, pharmacists and other interested professionals.",
"datePublished": "2022-05-28",
"url": "https://questionsmedicales.fr/article/36000642",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1590/1413-81232022279.19972021"
}
}
],
"breadcrumb": {
"@type": "BreadcrumbList",
"itemListElement": [
{
"@type": "ListItem",
"position": 1,
"name": "questionsmedicales.fr",
"item": "https://questionsmedicales.fr"
},
{
"@type": "ListItem",
"position": 2,
"name": "Maladies du système nerveux",
"item": "https://questionsmedicales.fr/mesh/D009422"
},
{
"@type": "ListItem",
"position": 3,
"name": "Maladies neuromusculaires",
"item": "https://questionsmedicales.fr/mesh/D009468"
},
{
"@type": "ListItem",
"position": 4,
"name": "Maladies musculaires",
"item": "https://questionsmedicales.fr/mesh/D009135"
},
{
"@type": "ListItem",
"position": 5,
"name": "Myopathies congénitales structurales",
"item": "https://questionsmedicales.fr/mesh/D020914"
},
{
"@type": "ListItem",
"position": 6,
"name": "Myopathie à axe central",
"item": "https://questionsmedicales.fr/mesh/D020512"
}
]
}
},
{
"@type": "MedicalWebPage",
"name": "Article complet : Myopathie à axe central - Questions et réponses",
"headline": "Questions et réponses médicales fréquentes sur Myopathie à axe central",
"description": "Une compilation de questions et réponses structurées, validées par des experts médicaux.",
"datePublished": "2025-05-19",
"inLanguage": "fr",
"hasPart": [
{
"@type": "MedicalWebPage",
"name": "Diagnostic",
"headline": "Diagnostic sur Myopathie à axe central",
"description": "Comment diagnostique-t-on la myopathie à axe central ?\nQuels tests génétiques sont utilisés ?\nQuels signes cliniques sont observés ?\nL'IRM est-elle utile pour le diagnostic ?\nQuel rôle joue l'historique familial ?",
"url": "https://questionsmedicales.fr/mesh/D020512?mesh_terms=Pharmacists#section-diagnostic"
},
{
"@type": "MedicalWebPage",
"name": "Symptômes",
"headline": "Symptômes sur Myopathie à axe central",
"description": "Quels sont les principaux symptômes ?\nLa myopathie affecte-t-elle tous les muscles ?\nY a-t-il des symptômes respiratoires ?\nLes symptômes varient-ils selon l'âge ?\nDes troubles de la marche sont-ils fréquents ?",
"url": "https://questionsmedicales.fr/mesh/D020512?mesh_terms=Pharmacists#section-symptômes"
},
{
"@type": "MedicalWebPage",
"name": "Prévention",
"headline": "Prévention sur Myopathie à axe central",
"description": "Peut-on prévenir la myopathie à axe central ?\nLe dépistage est-il recommandé ?\nDes conseils de vie peuvent-ils aider ?\nLes activités physiques sont-elles bénéfiques ?\nLes consultations régulières sont-elles nécessaires ?",
"url": "https://questionsmedicales.fr/mesh/D020512?mesh_terms=Pharmacists#section-prévention"
},
{
"@type": "MedicalWebPage",
"name": "Traitements",
"headline": "Traitements sur Myopathie à axe central",
"description": "Quels traitements sont disponibles ?\nLes médicaments sont-ils efficaces ?\nLa chirurgie est-elle une option ?\nComment la rééducation aide-t-elle ?\nY a-t-il des traitements expérimentaux ?",
"url": "https://questionsmedicales.fr/mesh/D020512?mesh_terms=Pharmacists#section-traitements"
},
{
"@type": "MedicalWebPage",
"name": "Complications",
"headline": "Complications sur Myopathie à axe central",
"description": "Quelles complications peuvent survenir ?\nLa myopathie peut-elle affecter la vie quotidienne ?\nY a-t-il un risque de cardiomyopathie ?\nLes infections sont-elles plus fréquentes ?\nComment gérer les complications ?",
"url": "https://questionsmedicales.fr/mesh/D020512?mesh_terms=Pharmacists#section-complications"
},
{
"@type": "MedicalWebPage",
"name": "Facteurs de risque",
"headline": "Facteurs de risque sur Myopathie à axe central",
"description": "Quels sont les facteurs de risque génétiques ?\nL'âge est-il un facteur de risque ?\nLe sexe influence-t-il le risque ?\nDes facteurs environnementaux jouent-ils un rôle ?\nLes maladies associées augmentent-elles le risque ?",
"url": "https://questionsmedicales.fr/mesh/D020512?mesh_terms=Pharmacists#section-facteurs de risque"
}
]
},
{
"@type": "FAQPage",
"mainEntity": [
{
"@type": "Question",
"name": "Comment diagnostique-t-on la myopathie à axe central ?",
"position": 1,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le diagnostic repose sur l'examen clinique, l'électromyogramme et la biopsie musculaire."
}
},
{
"@type": "Question",
"name": "Quels tests génétiques sont utilisés ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des tests génétiques peuvent identifier des mutations dans le gène RYR1, associé à cette myopathie."
}
},
{
"@type": "Question",
"name": "Quels signes cliniques sont observés ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "On observe souvent une faiblesse musculaire proximale et des anomalies dans les biopsies musculaires."
}
},
{
"@type": "Question",
"name": "L'IRM est-elle utile pour le diagnostic ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'IRM peut montrer des anomalies musculaires caractéristiques de la myopathie à axe central."
}
},
{
"@type": "Question",
"name": "Quel rôle joue l'historique familial ?",
"position": 5,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un historique familial de myopathies peut orienter le diagnostic vers une origine génétique."
}
},
{
"@type": "Question",
"name": "Quels sont les principaux symptômes ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les symptômes incluent faiblesse musculaire, fatigue et parfois des douleurs musculaires."
}
},
{
"@type": "Question",
"name": "La myopathie affecte-t-elle tous les muscles ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elle touche principalement les muscles proximaux, comme ceux des hanches et des épaules."
}
},
{
"@type": "Question",
"name": "Y a-t-il des symptômes respiratoires ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Dans certains cas, la faiblesse musculaire peut affecter les muscles respiratoires."
}
},
{
"@type": "Question",
"name": "Les symptômes varient-ils selon l'âge ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les symptômes peuvent apparaître dès l'enfance ou à l'âge adulte, selon les cas."
}
},
{
"@type": "Question",
"name": "Des troubles de la marche sont-ils fréquents ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, la faiblesse musculaire peut entraîner des difficultés à marcher ou à se lever."
}
},
{
"@type": "Question",
"name": "Peut-on prévenir la myopathie à axe central ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Étant génétique, il n'existe pas de prévention, mais un diagnostic précoce aide à la gestion."
}
},
{
"@type": "Question",
"name": "Le dépistage est-il recommandé ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le dépistage génétique peut être conseillé pour les familles à risque de transmission."
}
},
{
"@type": "Question",
"name": "Des conseils de vie peuvent-ils aider ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des conseils sur l'exercice et la nutrition peuvent améliorer la qualité de vie des patients."
}
},
{
"@type": "Question",
"name": "Les activités physiques sont-elles bénéfiques ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des activités adaptées peuvent aider à maintenir la force musculaire et la mobilité."
}
},
{
"@type": "Question",
"name": "Les consultations régulières sont-elles nécessaires ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des suivis réguliers permettent d'ajuster les traitements et surveiller l'évolution."
}
},
{
"@type": "Question",
"name": "Quels traitements sont disponibles ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Il n'existe pas de traitement curatif, mais la physiothérapie aide à maintenir la force musculaire."
}
},
{
"@type": "Question",
"name": "Les médicaments sont-ils efficaces ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des médicaments peuvent être prescrits pour gérer les symptômes, mais leur efficacité varie."
}
},
{
"@type": "Question",
"name": "La chirurgie est-elle une option ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "La chirurgie n'est généralement pas indiquée, sauf pour des complications spécifiques."
}
},
{
"@type": "Question",
"name": "Comment la rééducation aide-t-elle ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "La rééducation physique aide à améliorer la fonction musculaire et la qualité de vie."
}
},
{
"@type": "Question",
"name": "Y a-t-il des traitements expérimentaux ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des essais cliniques explorent des thérapies géniques et des traitements ciblés."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les complications incluent des problèmes respiratoires et des déformations musculo-squelettiques."
}
},
{
"@type": "Question",
"name": "La myopathie peut-elle affecter la vie quotidienne ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, la faiblesse musculaire peut limiter les activités quotidiennes et l'autonomie."
}
},
{
"@type": "Question",
"name": "Y a-t-il un risque de cardiomyopathie ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines formes de myopathie peuvent être associées à des problèmes cardiaques."
}
},
{
"@type": "Question",
"name": "Les infections sont-elles plus fréquentes ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les infections peuvent survenir en raison de la faiblesse musculaire et de l'immobilité."
}
},
{
"@type": "Question",
"name": "Comment gérer les complications ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une prise en charge multidisciplinaire est essentielle pour gérer les complications."
}
},
{
"@type": "Question",
"name": "Quels sont les facteurs de risque génétiques ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les antécédents familiaux de myopathies augmentent le risque de développer cette maladie."
}
},
{
"@type": "Question",
"name": "L'âge est-il un facteur de risque ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'âge d'apparition peut varier, mais les symptômes se manifestent souvent dans l'enfance."
}
},
{
"@type": "Question",
"name": "Le sexe influence-t-il le risque ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les myopathies peuvent affecter les deux sexes, mais certaines formes sont plus fréquentes chez les hommes."
}
},
{
"@type": "Question",
"name": "Des facteurs environnementaux jouent-ils un rôle ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Actuellement, les facteurs environnementaux ne sont pas clairement établis comme des risques."
}
},
{
"@type": "Question",
"name": "Les maladies associées augmentent-elles le risque ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines maladies auto-immunes peuvent coexister avec la myopathie, mais leur lien n'est pas direct."
}
}
]
}
]
}
Department of Neuromuscular Research, National Center of Neurology and Psychiatry (NCNP), National Institute of Neuroscience, 4-1-1 Ogawahigashi, Tokyo 187-8502, Japan; Medical Genome Center, NCNP, Tokyo, Kodaira, Japan. Electronic address: nishino@ncnp.go.jp.
INSERM, GIN-U1216, CHU Grenoble Alpes, Grenoble Institut Neurosciences, University Grenoble Alpes, Bat EJ Safra, Chemin Fortuné Ferrini, La Tronche, Grenoble, France.
INSERM, GIN-U1216, CHU Grenoble Alpes, Grenoble Institut Neurosciences, University Grenoble Alpes, Bat EJ Safra, Chemin Fortuné Ferrini, La Tronche, Grenoble, France.
Department of Neuromuscular Research, National Institute of Neuroscience, National Center of Neurology and Psychiatry, 187-8502 Tokyo, Japan; Department of Genome Medicine Development, Medical Genome Center, National Center of Neurology and Psychiatry, 187-8551 Tokyo, Japan.
From the Department of Learning, Informatics and Medical Education, Karolinska Institutet; Function Area Occupational Therapy and Physical Therapy, Allied Health Professionals Function, Karolinska University Hospital, Department of Neurobiology, Care Science and Society, Division of Physiotherapy and Department of Medicine, Karolinska Institutet; Division of Rheumatology, Rheumatology Unit, Department of Medicine, Karolinska Institutet, Solna, Sweden; Division of Rheumatology, Department of Medicine, Johns Hopkins University, Baltimore, Maryland, USA; Division of Rheumatology, Department of Internal Medicine, Medical Research Center, College of Medicine, Department of Molecular Medicine and Biopharmaceutical Sciences, Seoul National University, Seoul, Korea; Division of Rheumatology, Fiona Stanley Hospital, Institute for Immunology and Infectious Diseases, Murdoch University, Perth; The Notre Dame University Fremantle, Fremantle, Australia; Amsterdam UMC, University of Amsterdam, Department of Neurology, Amsterdam Neuroscience, Amsterdam, the Netherlands; Center for Global Health, University of Ottawa, Ottawa, Ontario, Canada.
M. Regardt, PhD, Occupational Therapist, Department of Learning, Informatics and Medical Education, Karolinska Institutet, and Function Area Occupational Therapy and Physical Therapy, Allied Health Professionals Function, Karolinska University Hospital; C.A. Mecoli, MD, Division of Rheumatology, Department of Medicine, Johns Hopkins University; J.K. Park, MD, PhD, Division of Rheumatology, Department of Internal Medicine, Seoul National University Hospital; I. de Groot, Patient Research Partner; C. Sarver, Patient Research Partner; M. Needham, MD, Division of Rheumatology, Fiona Stanley Hospital, Institute for Immunology and Infectious Diseases, Murdoch University, and The Notre Dame University; M. de Visser, MD, PhD, Amsterdam UMC, University of Amsterdam, Department of Neurology, Amsterdam Neuroscience; B. Shea, MSN, Center for Global Health, University of Ottawa; C.O. Bingham III, MD, Division of Rheumatology, Department of Medicine, Johns Hopkins University; I.E. Lundberg, MD, PhD, Division of Rheumatology, Rheumatology Unit, Department of Medicine, Karolinska Institutet; Y.W. Song, MD, PhD, Division of Rheumatology, Department of Internal Medicine, Medical Research Center, College of Medicine, Department of Molecular Medicine and Biopharmaceutical Sciences, Seoul National University; L. Christopher-Stine, MD, Division of Rheumatology, Department of Medicine, Johns Hopkins University; H. Alexanderson, PhD, Physiotherapist, Department of Neurobiology, Care Science and Society, Division of Physiotherapy and Department of Medicine Solna, Karolinska Institutet, and Function Area Occupational Therapy and Physical Therapy, Allied Health Professionals Function, Karolinska University Hospital. M. Regardt and Dr. C. Mecoli are co-first authors.
Department of Neuromuscular Research, National Center of Neurology and Psychiatry (NCNP), National Institute of Neuroscience, 4-1-1 Ogawahigashi, Tokyo 187-8502, Japan; Medical Genome Center, NCNP, Tokyo, Kodaira, Japan; Department of Pediatrics, Showa General Hospital, Tokyo, Kodaira, Japan.
INSERM, GIN-U1216, CHU Grenoble Alpes, Grenoble Institut Neurosciences, University Grenoble Alpes, Bat EJ Safra, Chemin Fortuné Ferrini, La Tronche, Grenoble, France.
INSERM, GIN-U1216, CHU Grenoble Alpes, Grenoble Institut Neurosciences, University Grenoble Alpes, Bat EJ Safra, Chemin Fortuné Ferrini, La Tronche, Grenoble, France. isabelle.marty@univ-grenoble-alpes.fr.
Neuromuscular Morphology Unit, Myology Institute, Groupe Hospitalier Universitaire La Pitié-Salpêtrière, Paris, France. matteo.garibaldi@uniroma1.it.
Unit of Neuromuscular Diseases, Neuromuscular Disease Centre, Department of Neurology Mental Health and Sensory Organs (NESMOS), Faculty of Medicine and Psychology, SAPIENZA University of Rome, Sant'Andrea Hospital, Via di Grottarossa 1035-1039, 00189, Rome, Italy. matteo.garibaldi@uniroma1.it.
Service Neurologie Médicale, Centre de Référence Maladies Neuromusculaire Paris-Est-Ile de France, CHU Raymond-Poincaré Paris Ouest, Garches, France.
U1179 UVSQ-INSERM Handicap Neuromusculaire: Physiologie, Biothérapie et Pharmacologie appliquées, UFR des sciences de la santé Simone Veil, Université Versailles-Saint-Quentin-en-Yvelines, Versailles, France.
Unit of Neuromuscular Diseases, Neuromuscular Disease Centre, Department of Neurology Mental Health and Sensory Organs (NESMOS), Faculty of Medicine and Psychology, SAPIENZA University of Rome, Sant'Andrea Hospital, Via di Grottarossa 1035-1039, 00189, Rome, Italy.
Despite the usefulness of assertiveness by healthcare professionals in improving patient safety, few studies have evaluated the assertiveness of community pharmacists. Community pharmacists' assertive...
Our objective was to examine which types of assertiveness-related self-expression are associated with community pharmacist-initiated prescribing changes while adjusting for possible confounding factor...
We conducted a cross-sectional survey in Japan between May and October 2022 in 10 prefectures. Community pharmacists belonging to a large pharmacy chain were recruited. The outcome variable was the fr...
Of 3346 community pharmacists invited, 963 were included in the analysis. Participants with high assertive self-expression scores had a significantly higher frequency of pharmacist-initiated prescript...
Higher assertive self-expression among community pharmacists is associated with higher frequency of pharmacist-initiated prescription changes....
Prescription-related errors and misinterpretation of oral cancer treatment instructions can lead to significant harm or fatal outcomes for patients. The impact of specialist pharmacist-led consultatio...
To evaluate the impact of specialist cancer pharmacist patient consultation in a pharmacist-led anticancer clinic across a range of cancer types and evaluate health service staff perceptions of these ...
Retrospective data were collected from electronic patient medical records from 2017 to 2020 at a Western Australian quaternary hospital. The impacts of pharmacist clinical interventions were classifie...
Of 246 patients reviewed, 76 (30.8%, p < .001) had received a clinical intervention of which 48 (63.2%) were classified as high-extreme and 28 (36.8%) as low-moderate impact (p = .021). Patients on ≥5...
Specialist pharmacist-led patient consultation for patients on OAM regimens may protect patients from high and extreme risk of harm. Specialist interdisciplinary staff supported this service....
Practice-based pharmacists (PBPs) have been introduced into general practice across the UK to relieve some of the pressures within primary care. However, there is little existing UK literature that ha...
To explore the views and experiences of GPs, PBPs, and community pharmacists (CPs) about PBPs' integration into general practice and their impact on primary healthcare delivery....
A qualitative interview study in primary care in Northern Ireland....
Purposive and snowball sampling were used to recruit triads (a GP, a PBP, and a CP) from across five administrative healthcare areas in Northern Ireland. Sampling of practices to recruit GPs and PBPs ...
Eleven triads were recruited from across the five administrative areas. Four main themes in relation to PBPs' integration into general practices were revealed: evolution of the role; PBP attributes; c...
Participants reported that PBPs had integrated well and perceived a positive impact on primary healthcare delivery. Further work is needed to increase patient awareness of the PBP role....
Pharmacists were acknowledged as the most appropriate healthcare professional to dispense mifepristone for medication abortion shortly after the prescription therapy became available in January 2017 i...
We aimed to identify the facilitators and barriers for successful initiation and ongoing dispensing of mifepristone among community pharmacists across Canada....
We surveyed community pharmacists from urban/rural practice settings across Canada by recruiting from January 2017 to January 2019 through pharmacist organisations, professional networks, at mifeprist...
Of the 433 responses from dispensing community pharmacists across 10/13 Canadian provinces and territories, 93.1% indicated they were willing and ready to dispense mifepristone. Key facilitators were ...
Pharmacist respondents from across Canada reported being able and willing to dispense mifepristone and rarely mentioned barriers to stocking/dispensing the medication in the community pharmacy setting...
Pharmacist prescribing is a growing reality in some developed counties, with varied health systems. Understanding the contribution that this activity can offer in the healthcare process, and investiga...
Opioid stewardship is one essential function of pain and palliative care pharmacists and a critical need in the United States. In recent years, this country has been plagued by two public health emerg...
No studies in Japan have examined whether dispensing by family pharmacists, who are incentivized by reimbursement to provide continuous and exclusive medication management, results in prescription cha...
We identified 333,503 records of pharmacy claims data from patients aged 65 years or older who received medication instructions at outpatient pharmacies at Tsukuba, a medium-sized city near Tokyo, bet...
Dispensing by family pharmacists was 1.37 times more likely to involve a record of prescription change than dispensing by non-family pharmacists. Older age, female sex, polypharmacy, and small-scale p...
This study indicated that dispensing by family pharmacists was a potential factor for pharmacist-initiated prescription changes that may prevent excessive medication and limit pharmacological interact...
Nasal colonization with methicillin-resistant...
The purpose of this study is to determine the impact of a pharmacist-driven algorithm, utilizing MRSA PCR nasal screening on duration of anti-MRSA therapy in patients admitted to the intensive care un...
A single-center pre/post study was conducted in 4 ICUs at a large tertiary care community hospital. Adult patients admitted to the ICU initiated on vancomycin or linezolid for pneumonia managed using ...
Of the 245 patients screened, 50 patients met inclusion criteria for the algorithm cohort and were matched to 50 patients in the historical cohort. The duration of anti-MRSA therapy was significantly ...
A pharmacist-driven MRSA PCR algorithm significantly reduced anti-MRSA duration of therapy in critically ill patients with pneumonia. Future studies should validate these results in critically ill pop...
Late-life depression often goes underdiagnosed and undertreated, affecting the quality of life of older adults. Pharmacists are well-placed to identify older adults who may be at risk of depression by...
To explore community pharmacists' acceptability of performing late-life depression screening in Australian community pharmacies....
Semi-structured interviews with community pharmacists were conducted to gauge their perceptions regarding delivering depression screening services for older adults. Data analysis was conducted using a...
Fifteen pharmacists were interviewed, 12 of whom were female and 11 of whom practised in a metropolitan area. Four key themes were identified including: training needs, environmental factors, pharmaci...
The findings of this study demonstrate that while community pharmacists found depression screening for older adults in community pharmacies to be an acceptable service, there remains a need for the de...
This study explores how pharmacists legitimise the expansion of their clinical work and considers its impact on pharmacists' professional identity work. In the context of pharmacy in the English NHS, ...