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Stabilité de l'ARN : Questions médicales fréquentes
Questions fréquentes et termes MeSH associés
Diagnostic 5
#1
Comment évaluer la stabilité de l'ARN ?
On utilise des techniques comme le Northern blot et la PCR en temps réel.
#2
Quels marqueurs indiquent une instabilité de l'ARN ?
Des niveaux élevés de dégradation et des variations dans l'expression génique peuvent indiquer une instabilité.
#3
Quels tests sont utilisés pour mesurer l'ARN ?
Les tests incluent l'électrophorèse et les analyses de séquençage.
#4
Peut-on détecter des anomalies d'ARN ?
Oui, des techniques comme le séquençage de nouvelle génération peuvent détecter des anomalies.
#5
Quel rôle joue l'ARNm dans le diagnostic ?
L'ARNm est crucial pour évaluer l'expression des gènes associés à des maladies.
Symptômes 5
#1
Quels symptômes sont liés à l'instabilité de l'ARN ?
Des symptômes variés peuvent apparaître, selon la maladie sous-jacente, comme la fatigue.
#2
L'instabilité de l'ARN peut-elle causer des maladies ?
Oui, elle est liée à des maladies comme certains cancers et des troubles neurodégénératifs.
#3
Quels signes cliniques sont observés ?
Les signes peuvent inclure des anomalies de croissance ou des troubles métaboliques.
#4
Y a-t-il des symptômes spécifiques aux maladies liées à l'ARN ?
Oui, des symptômes spécifiques peuvent inclure des troubles neurologiques ou immunitaires.
#5
Comment l'instabilité de l'ARN affecte-t-elle la santé ?
Elle peut perturber l'expression génique, entraînant des dysfonctionnements cellulaires.
Prévention 5
#1
Comment prévenir l'instabilité de l'ARN ?
Une alimentation équilibrée et un mode de vie sain peuvent aider à maintenir la stabilité de l'ARN.
#2
Y a-t-il des facteurs environnementaux à éviter ?
Oui, l'exposition à des toxines et à des radiations peut affecter la stabilité de l'ARN.
#3
L'exercice physique influence-t-il l'ARN ?
Oui, l'exercice régulier peut améliorer la santé cellulaire et la stabilité de l'ARN.
#4
Des suppléments peuvent-ils aider ?
Certains suppléments, comme les antioxydants, peuvent soutenir la stabilité de l'ARN.
#5
Comment le stress affecte-t-il l'ARN ?
Le stress chronique peut altérer la stabilité de l'ARN et affecter l'expression génique.
Traitements 5
#1
Quels traitements ciblent l'instabilité de l'ARN ?
Des thérapies géniques et des médicaments stabilisateurs d'ARN sont en développement.
#2
Peut-on utiliser des inhibiteurs pour stabiliser l'ARN ?
Oui, certains inhibiteurs peuvent réduire la dégradation de l'ARN dans les cellules.
#3
Quels médicaments sont efficaces contre l'instabilité de l'ARN ?
Des médicaments comme les antisens oligonucleotides sont utilisés pour cibler l'ARN.
#4
Comment la thérapie génique aide-t-elle ?
Elle peut corriger les défauts d'ARN, améliorant ainsi l'expression génique.
#5
Y a-t-il des traitements expérimentaux ?
Oui, des essais cliniques testent de nouvelles approches pour stabiliser l'ARN.
Complications 5
#1
Quelles complications peuvent survenir ?
Des complications incluent des maladies génétiques, des cancers et des troubles métaboliques.
#2
L'instabilité de l'ARN peut-elle entraîner des cancers ?
Oui, l'instabilité de l'ARN est souvent associée à des mécanismes tumoraux.
#3
Quels troubles métaboliques sont liés à l'ARN ?
Des troubles comme le diabète et l'obésité peuvent être influencés par l'instabilité de l'ARN.
#4
Y a-t-il des risques neurologiques ?
Oui, des maladies neurodégénératives peuvent être exacerbées par l'instabilité de l'ARN.
#5
Comment l'instabilité de l'ARN affecte-t-elle le système immunitaire ?
Elle peut altérer la réponse immunitaire, rendant l'organisme plus vulnérable aux infections.
Facteurs de risque 5
#1
Quels facteurs génétiques influencent l'ARN ?
Des mutations dans des gènes régulateurs peuvent affecter la stabilité de l'ARN.
#2
L'âge est-il un facteur de risque ?
Oui, le vieillissement peut affecter la stabilité de l'ARN et l'expression génique.
#3
Les infections virales impactent-elles l'ARN ?
Certaines infections virales peuvent perturber la stabilité de l'ARN dans les cellules hôtes.
#4
Le tabagisme influence-t-il l'ARN ?
Oui, le tabagisme peut induire des modifications qui affectent la stabilité de l'ARN.
#5
Y a-t-il des facteurs nutritionnels à considérer ?
Oui, une carence en nutriments essentiels peut compromettre la stabilité de l'ARN.
Contenu validé par Dr Olivier Menir
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 26/04/2025
Contenu vérifié selon les dernières recommandations médicales
Auteurs principaux
Hannah K Wayment-Steele
3 publications dans cette catégorie
Affiliations :
- Department of Chemistry, Stanford University, Stanford, CA 94305, USA.
- Eterna Massive Open Laboratory.
Publications dans "Stabilité de l'ARN" :
-
Theoretical basis for stabilizing messenger RNA through secondary structure design.
Nucleic acids research
-
Combinatorial optimization of mRNA structure, stability, and translation for RNA-based therapeutics.
Nature communications 2022-03-22
-
Combinatorial optimization of mRNA structure, stability, and translation for RNA-based therapeutics.
bioRxiv : the preprint server for biology 2021-03-30
Do Soon Kim
3 publications dans cette catégorie
Affiliations :
- Eterna Massive Open Laboratory.
- Department of Chemical and Biological Engineering, Northwestern University, Evanston, IL 60208, USA.
- Department of Biochemistry, Stanford University, Stanford, CA 94305, USA.
Publications dans "Stabilité de l'ARN" :
-
Theoretical basis for stabilizing messenger RNA through secondary structure design.
Nucleic acids research
-
Combinatorial optimization of mRNA structure, stability, and translation for RNA-based therapeutics.
Nature communications 2022-03-22
-
Combinatorial optimization of mRNA structure, stability, and translation for RNA-based therapeutics.
bioRxiv : the preprint server for biology 2021-03-30
John J Nicol
3 publications dans cette catégorie
Affiliations :
- Eterna Massive Open Laboratory.
Publications dans "Stabilité de l'ARN" :
-
Theoretical basis for stabilizing messenger RNA through secondary structure design.
Nucleic acids research
-
Combinatorial optimization of mRNA structure, stability, and translation for RNA-based therapeutics.
Nature communications 2022-03-22
-
Combinatorial optimization of mRNA structure, stability, and translation for RNA-based therapeutics.
bioRxiv : the preprint server for biology 2021-03-30
Roger Wellington-Oguri
3 publications dans cette catégorie
Affiliations :
- Eterna Massive Open Laboratory.
Publications dans "Stabilité de l'ARN" :
-
Theoretical basis for stabilizing messenger RNA through secondary structure design.
Nucleic acids research
-
Combinatorial optimization of mRNA structure, stability, and translation for RNA-based therapeutics.
Nature communications 2022-03-22
-
Combinatorial optimization of mRNA structure, stability, and translation for RNA-based therapeutics.
bioRxiv : the preprint server for biology 2021-03-30
Andrew M Watkins
3 publications dans cette catégorie
Affiliations :
- Eterna Massive Open Laboratory.
- Department of Biochemistry, Stanford University, Stanford, CA 94305, USA.
Publications dans "Stabilité de l'ARN" :
-
Theoretical basis for stabilizing messenger RNA through secondary structure design.
Nucleic acids research
-
Combinatorial optimization of mRNA structure, stability, and translation for RNA-based therapeutics.
Nature communications 2022-03-22
-
Combinatorial optimization of mRNA structure, stability, and translation for RNA-based therapeutics.
bioRxiv : the preprint server for biology 2021-03-30
Eterna Participants
3 publications dans cette catégorie
Affiliations :
- Eterna Massive Open Laboratory.
Publications dans "Stabilité de l'ARN" :
-
Theoretical basis for stabilizing messenger RNA through secondary structure design.
Nucleic acids research
-
Combinatorial optimization of mRNA structure, stability, and translation for RNA-based therapeutics.
Nature communications 2022-03-22
-
Combinatorial optimization of mRNA structure, stability, and translation for RNA-based therapeutics.
bioRxiv : the preprint server for biology 2021-03-30
Rhiju Das
3 publications dans cette catégorie
Affiliations :
- Eterna Massive Open Laboratory.
- Department of Biochemistry, Stanford University, Stanford, CA 94305, USA.
- Department of Physics, Stanford University, Stanford, CA 94305, USA.
Publications dans "Stabilité de l'ARN" :
-
Theoretical basis for stabilizing messenger RNA through secondary structure design.
Nucleic acids research
-
Combinatorial optimization of mRNA structure, stability, and translation for RNA-based therapeutics.
Nature communications 2022-03-22
-
Combinatorial optimization of mRNA structure, stability, and translation for RNA-based therapeutics.
bioRxiv : the preprint server for biology 2021-03-30
Nina Fasching
2 publications dans cette catégorie
Affiliations :
- IMBA-Institute of Molecular Biotechnology, Vienna Biocenter (VBC), Vienna, Austria.
Publications dans "Stabilité de l'ARN" :
-
Transcriptome-Wide Profiling of RNA Stability.
Methods in molecular biology (Clifton, N.J.)
-
Determining mRNA Stability by Metabolic RNA Labeling and Chemical Nucleoside Conversion.
Methods in molecular biology (Clifton, N.J.)
Veronika A Herzog
2 publications dans cette catégorie
Affiliations :
- IMBA-Institute of Molecular Biotechnology, Vienna Biocenter (VBC), Vienna, Austria.
Publications dans "Stabilité de l'ARN" :
-
Transcriptome-Wide Profiling of RNA Stability.
Methods in molecular biology (Clifton, N.J.)
-
Determining mRNA Stability by Metabolic RNA Labeling and Chemical Nucleoside Conversion.
Methods in molecular biology (Clifton, N.J.)
Stefan L Ameres
2 publications dans cette catégorie
Affiliations :
- IMBA-Institute of Molecular Biotechnology, Vienna Biocenter (VBC), Vienna, Austria. stefan.ameres@univie.ac.at.
- Max Perutz Labs, University of Vienna, Vienna Biocenter (VBC), Vienna, Austria. stefan.ameres@univie.ac.at.
Publications dans "Stabilité de l'ARN" :
-
Transcriptome-Wide Profiling of RNA Stability.
Methods in molecular biology (Clifton, N.J.)
-
Determining mRNA Stability by Metabolic RNA Labeling and Chemical Nucleoside Conversion.
Methods in molecular biology (Clifton, N.J.)
Besik Kankia
2 publications dans cette catégorie
Affiliations :
- Department of Chemistry and Biochemistry, The Ohio State University, Columbus, OH 43210, USA.
- Center for RNA Biology, The Ohio State University, Columbus, OH 43210, USA.
- Institute of Biophysics, Ilia State University, Tbilisi, 0162, Republic of Georgia.
Publications dans "Stabilité de l'ARN" :
-
A Chimeric DNA/RNA Antiparallel Quadruplex with Improved Stability.
ChemistryOpen
-
Stability Factors of the Parallel Quadruplexes: DNA Versus RNA.
The journal of physical chemistry. B 2019-01-25
Amos J Nissley
2 publications dans cette catégorie
Affiliations :
- Department of Chemistry, University of California, Berkeley, Berkeley, California 94720, USA.
Publications dans "Stabilité de l'ARN" :
-
Interactions between terminal ribosomal RNA helices stabilize the
RNA (New York, N.Y.) 2023-07-07
-
Rare ribosomal RNA sequences from archaea stabilize the bacterial ribosome.
Nucleic acids research
Jamie H D Cate
2 publications dans cette catégorie
Affiliations :
- Department of Chemistry, University of California, Berkeley, Berkeley, California 94720, USA j-h-doudna-cate@berkeley.edu.
- Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, California 94720, USA.
- Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720, USA.
Publications dans "Stabilité de l'ARN" :
-
Interactions between terminal ribosomal RNA helices stabilize the
RNA (New York, N.Y.) 2023-07-07
-
Rare ribosomal RNA sequences from archaea stabilize the bacterial ribosome.
Nucleic acids research
Seyed-Fakhreddin Torabi
2 publications dans cette catégorie
Affiliations :
- Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06536.
- HHMI, Yale University School of Medicine, New Haven, CT 06536.
Publications dans "Stabilité de l'ARN" :
-
Structural analyses of an RNA stability element interacting with poly(A).
Proceedings of the National Academy of Sciences of the United States of America
-
RNA stabilization by a poly(A) tail 3'-end binding pocket and other modes of poly(A)-RNA interaction.
Science (New York, N.Y.) 2021-01-07
Jimin Wang
2 publications dans cette catégorie
Affiliations :
- Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06536.
Publications dans "Stabilité de l'ARN" :
-
Structural analyses of an RNA stability element interacting with poly(A).
Proceedings of the National Academy of Sciences of the United States of America
-
RNA stabilization by a poly(A) tail 3'-end binding pocket and other modes of poly(A)-RNA interaction.
Science (New York, N.Y.) 2021-01-07
Suzanne J DeGregorio
2 publications dans cette catégorie
Affiliations :
- Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06536.
- HHMI, Yale University School of Medicine, New Haven, CT 06536.
Publications dans "Stabilité de l'ARN" :
-
Structural analyses of an RNA stability element interacting with poly(A).
Proceedings of the National Academy of Sciences of the United States of America
-
RNA stabilization by a poly(A) tail 3'-end binding pocket and other modes of poly(A)-RNA interaction.
Science (New York, N.Y.) 2021-01-07
Anand T Vaidya
2 publications dans cette catégorie
Affiliations :
- Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06536.
- HHMI, Yale University School of Medicine, New Haven, CT 06536.
- Tata Institute of Fundamental Research Centre for Interdisciplinary Sciences, Tata Institute of Fundamental Research, 10 500046 Hyderabad, India.
Publications dans "Stabilité de l'ARN" :
-
Structural analyses of an RNA stability element interacting with poly(A).
Proceedings of the National Academy of Sciences of the United States of America
-
RNA stabilization by a poly(A) tail 3'-end binding pocket and other modes of poly(A)-RNA interaction.
Science (New York, N.Y.) 2021-01-07
Joan A Steitz
2 publications dans cette catégorie
Affiliations :
- Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06536; wahc@stanford.edu LP26@cornell.edu joan.steitz@yale.edu.
- HHMI, Yale University School of Medicine, New Haven, CT 06536.
Publications dans "Stabilité de l'ARN" :
-
Structural analyses of an RNA stability element interacting with poly(A).
Proceedings of the National Academy of Sciences of the United States of America
-
RNA stabilization by a poly(A) tail 3'-end binding pocket and other modes of poly(A)-RNA interaction.
Science (New York, N.Y.) 2021-01-07
Jorge R Espinosa
2 publications dans cette catégorie
Affiliations :
- Cavendish Laboratory, Maxwell Centre, Department of Physics, University of Cambridge, Cambridge, United Kingdom. Electronic address: jr752@cam.ac.uk.
Publications dans "Stabilité de l'ARN" :
-
'RNA modulation of transport properties and stability in phase-separated condensates.
Biophysical journal 2021-11-09
-
RNA length has a non-trivial effect in the stability of biomolecular condensates formed by RNA-binding proteins.
PLoS computational biology 2022-02-02
Kathrin Leppek
2 publications dans cette catégorie
Affiliations :
- Department of Genetics, Stanford University, Stanford, CA, 94305, USA.
Publications dans "Stabilité de l'ARN" :
-
Combinatorial optimization of mRNA structure, stability, and translation for RNA-based therapeutics.
Nature communications 2022-03-22
-
Combinatorial optimization of mRNA structure, stability, and translation for RNA-based therapeutics.
bioRxiv : the preprint server for biology 2021-03-30
Sources (10000 au total)
Information technology capability, open technological innovation and firm growth.
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College English Multimodal Teaching Based on Digital Information Technology.
In the era of in-depth application of knowledge technology in the field of education, the teaching mode combining school English teaching and network data technology is widely used in school English e...
The UPPS model of impulsivity in the abuse of Information and Communication Technologies (ICT).
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Information and communication technology development and health gap nexus in Africa.
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The Effect of Nursing Internships on the Effectiveness of Implementing Information Technology Teaching.
In nursing education, the diversity of clinical scenarios is complex and dynamic, and it is a challenge for nursing students to learn this clinical knowledge in conventional teaching mechanisms. Howev...
Use of information and communication technology in occupational therapy for older adults.
Information and communication technology (ICT) provides one solution to meet increasing demands for occupational therapy for older adults.... To examine if and how municipality-based occupational therapists (OTs) include ICT in their work, and which factors are associated with use of occupational therapy at a distance.... Survey study including 167 OTs. Data were presented descriptively. Associations were analysed by Chi... Forty-eight percent of OTs used ICT once a month or more. OTs belief on possibilites to use ICT is associated with replacement of physical home visits. Managers expectations and support also seem to b... ICT solutions are frequently used by OTs in home health care and can be considered complementing rather than replacing physical home visits. More knowledge is needed on when and how ICT solutions can ...
Assistive technology, information asymmetry and the role of brokerage services: a scoping review.
Access to assistive technologies (ATs) is a human right for people with disabilities, but there are a range of barriers, including lack of adequate information. This review aimed to explore the implic... Scoping review.... EBSCO Medline, EBSCO Cinahl, Academic Search Ultimate, Business Source Ultimate, Proquest Central, Scopus, Web of Science, PsychINFO, EconLit and JSTOR were searched through 18 July 2021.... Intervention and observational studies and articles directly related to information asymmetry and brokerage in the context of AT were included. In addition, a scan of web-based resources and services ... Four authors independently screened the articles for inclusion and performed a narrative synthesis.... Thirty-three articles were identified. The narrative synthesis showed that: (1) AT users want access to impartial information sources; (2) users want to be involved in AT selection; (3) users benefit ... Access to impartial information brokerage is critical to optimise AT selection. The implications of information asymmetry include lower user satisfaction, equipment underutilisation or abandonment. As...