questionsmedicales.fr
Enzymes et coenzymes
Enzymes
Hydrolases
Peptide hydrolases
Metalloproteases
Metalloproteases : Questions médicales fréquentes
Termes MeSH sélectionnés :
Diagnostic
5
Métalloprotéases
Biopsie
Tests sanguins
Marqueurs biologiques
Métalloprotéases
Sérum
Imagerie médicale
Métalloprotéases
Tissus
Tests génétiques
Métalloprotéases
Mutations
Activité enzymatique
Métalloprotéases
Échantillons biologiques
Symptômes
5
Inflammation
Métalloprotéases
Douleurs articulaires
Métalloprotéases
Symptômes
Tissus
Cicatrisation
Métalloprotéases
Matrice extracellulaire
Asymptomatique
Métalloprotéases
Dysfonction
Âge
Métalloprotéases
Symptômes dégénératifs
Prévention
5
Prévention
Métalloprotéases
Mode de vie sain
Suppléments nutritionnels
Métalloprotéases
Antioxydants
Alimentation
Métalloprotéases
Inflammation
Stress
Métalloprotéases
Gestion du stress
Examens médicaux
Métalloprotéases
Déséquilibres enzymatiques
Traitements
5
Inhibiteurs
Métalloprotéases
Traitements
Thérapie génique
Métalloprotéases
Mutations
Anti-inflammatoires
Métalloprotéases
Inflammation
Médecine personnalisée
Métalloprotéases
Traitements
Effets secondaires
Inhibiteurs
Métalloprotéases
Complications
5
Complications
Métalloprotéases
Arthrite
Réversibilité
Métalloprotéases
Traitement
Qualité de vie
Métalloprotéases
Douleurs chroniques
Prévisibilité
Métalloprotéases
Surveillance
Complications
Métalloprotéases
Cicatrisation
Facteurs de risque
5
Facteurs de risque
Métalloprotéases
Mode de vie
Antécédents familiaux
Métalloprotéases
Risque
Tabagisme
Métalloprotéases
Maladies
Stress chronique
Métalloprotéases
Risque
Toxines
Métalloprotéases
Environnement
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"description": "Comment prévenir les maladies liées aux métalloprotéases ?\nLes suppléments nutritionnels sont-ils utiles ?\nL'évitement de certains aliments est-il recommandé ?\nLe contrôle du stress est-il important ?\nLes examens réguliers sont-ils nécessaires ?",
"url": "https://questionsmedicales.fr/mesh/D045726?mesh_terms=Cognition#section-prévention"
},
{
"@type": "MedicalWebPage",
"name": "Traitements",
"headline": "Traitements sur Metalloproteases",
"description": "Quels traitements ciblent les métalloprotéases ?\nLes thérapies géniques sont-elles une option ?\nComment les anti-inflammatoires aident-ils ?\nLes traitements sont-ils personnalisés ?\nQuels sont les effets secondaires des inhibiteurs ?",
"url": "https://questionsmedicales.fr/mesh/D045726?mesh_terms=Cognition#section-traitements"
},
{
"@type": "MedicalWebPage",
"name": "Complications",
"headline": "Complications sur Metalloproteases",
"description": "Quelles complications peuvent survenir avec une suractivité ?\nLes complications sont-elles réversibles ?\nComment les complications affectent-elles la qualité de vie ?\nLes complications sont-elles prévisibles ?\nQuelles sont les complications liées à une déficience ?",
"url": "https://questionsmedicales.fr/mesh/D045726?mesh_terms=Cognition#section-complications"
},
{
"@type": "MedicalWebPage",
"name": "Facteurs de risque",
"headline": "Facteurs de risque sur Metalloproteases",
"description": "Quels facteurs augmentent le risque de dysfonction ?\nLes antécédents familiaux jouent-ils un rôle ?\nLe tabagisme est-il un facteur de risque ?\nLe stress chronique influence-t-il le risque ?\nL'exposition à des toxines est-elle un facteur ?",
"url": "https://questionsmedicales.fr/mesh/D045726?mesh_terms=Cognition#section-facteurs de risque"
}
]
},
{
"@type": "FAQPage",
"mainEntity": [
{
"@type": "Question",
"name": "Comment diagnostiquer une dysfonction des métalloprotéases ?",
"position": 1,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des tests sanguins et des biopsies tissulaires peuvent évaluer l'activité des métalloprotéases."
}
},
{
"@type": "Question",
"name": "Quels marqueurs sont utilisés pour le diagnostic ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les niveaux de métalloprotéases dans le sérum ou les tissus peuvent servir de marqueurs diagnostiques."
}
},
{
"@type": "Question",
"name": "Les imageries sont-elles utiles pour le diagnostic ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'imagerie peut aider à visualiser les tissus affectés par des déséquilibres enzymatiques."
}
},
{
"@type": "Question",
"name": "Quels tests génétiques sont disponibles ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des tests génétiques peuvent identifier des mutations affectant la production de métalloprotéases."
}
},
{
"@type": "Question",
"name": "Comment évaluer l'activité enzymatique ?",
"position": 5,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des tests enzymatiques spécifiques mesurent l'activité des métalloprotéases dans les échantillons."
}
},
{
"@type": "Question",
"name": "Quels symptômes indiquent une surproduction de métalloprotéases ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une inflammation, des douleurs articulaires et des lésions tissulaires peuvent survenir."
}
},
{
"@type": "Question",
"name": "Les symptômes varient-ils selon le type de métalloprotéases ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, différents types de métalloprotéases peuvent causer des symptômes variés selon les tissus affectés."
}
},
{
"@type": "Question",
"name": "Quels signes cliniques sont associés à une déficience ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une cicatrisation lente et des anomalies dans la matrice extracellulaire peuvent être observées."
}
},
{
"@type": "Question",
"name": "Les symptômes sont-ils toujours visibles ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Non, certaines dysfonctions peuvent être asymptomatiques jusqu'à des stades avancés."
}
},
{
"@type": "Question",
"name": "Comment les symptômes évoluent-ils avec l'âge ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'activité des métalloprotéases peut augmenter avec l'âge, aggravant les symptômes dégénératifs."
}
},
{
"@type": "Question",
"name": "Comment prévenir les maladies liées aux métalloprotéases ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un mode de vie sain, incluant une alimentation équilibrée et de l'exercice, peut aider."
}
},
{
"@type": "Question",
"name": "Les suppléments nutritionnels sont-ils utiles ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certains suppléments, comme les antioxydants, peuvent soutenir la fonction des métalloprotéases."
}
},
{
"@type": "Question",
"name": "L'évitement de certains aliments est-il recommandé ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, réduire les aliments pro-inflammatoires peut aider à réguler l'activité des métalloprotéases."
}
},
{
"@type": "Question",
"name": "Le contrôle du stress est-il important ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le stress peut influencer l'activité des métalloprotéases, donc sa gestion est cruciale."
}
},
{
"@type": "Question",
"name": "Les examens réguliers sont-ils nécessaires ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des examens réguliers peuvent aider à détecter précocement des déséquilibres enzymatiques."
}
},
{
"@type": "Question",
"name": "Quels traitements ciblent les métalloprotéases ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des inhibiteurs spécifiques des métalloprotéases sont utilisés pour traiter certaines maladies."
}
},
{
"@type": "Question",
"name": "Les thérapies géniques sont-elles une option ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, la thérapie génique peut corriger des mutations affectant la production de métalloprotéases."
}
},
{
"@type": "Question",
"name": "Comment les anti-inflammatoires aident-ils ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Ils peuvent réduire l'inflammation causée par une suractivité des métalloprotéases."
}
},
{
"@type": "Question",
"name": "Les traitements sont-ils personnalisés ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les traitements peuvent être adaptés en fonction du type de métalloprotéases impliqué."
}
},
{
"@type": "Question",
"name": "Quels sont les effets secondaires des inhibiteurs ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les inhibiteurs peuvent causer des effets secondaires comme des troubles gastro-intestinaux."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir avec une suractivité ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des maladies dégénératives, comme l'arthrite, peuvent résulter d'une suractivité des métalloprotéases."
}
},
{
"@type": "Question",
"name": "Les complications sont-elles réversibles ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines complications peuvent être réversibles avec un traitement approprié, d'autres non."
}
},
{
"@type": "Question",
"name": "Comment les complications affectent-elles la qualité de vie ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elles peuvent entraîner des douleurs chroniques et une mobilité réduite, affectant la qualité de vie."
}
},
{
"@type": "Question",
"name": "Les complications sont-elles prévisibles ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines complications peuvent être prévisibles en surveillant les niveaux d'activité enzymatique."
}
},
{
"@type": "Question",
"name": "Quelles sont les complications liées à une déficience ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une cicatrisation lente et des infections peuvent survenir en raison d'une déficience en métalloprotéases."
}
},
{
"@type": "Question",
"name": "Quels facteurs augmentent le risque de dysfonction ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'âge, le mode de vie sédentaire et une alimentation déséquilibrée augmentent le risque."
}
},
{
"@type": "Question",
"name": "Les antécédents familiaux jouent-ils un rôle ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des antécédents familiaux de maladies liées aux métalloprotéases peuvent augmenter le risque."
}
},
{
"@type": "Question",
"name": "Le tabagisme est-il un facteur de risque ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le tabagisme peut exacerber l'activité des métalloprotéases et augmenter les maladies associées."
}
},
{
"@type": "Question",
"name": "Le stress chronique influence-t-il le risque ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le stress chronique peut perturber l'équilibre des métalloprotéases, augmentant le risque de maladies."
}
},
{
"@type": "Question",
"name": "L'exposition à des toxines est-elle un facteur ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'exposition à certaines toxines environnementales peut affecter l'activité des métalloprotéases."
}
}
]
}
]
}
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 11/03/2025
Contenu vérifié selon les dernières recommandations médicales
4 publications dans cette catégorie
Affiliations :
Departamento de Bioquímica y Biología Molecular, Universidad de Oviedo, 33006 Oviedo, Spain.
Departamento de Investigación, Instituto Ordóñez, 33012 Oviedo, Spain.
Publications dans "Metalloproteases" :
4 publications dans cette catégorie
Affiliations :
Departamento de Bioquímica y Biología Molecular, Universidad de Oviedo, 33006 Oviedo, Spain.
Publications dans "Metalloproteases" :
4 publications dans cette catégorie
Affiliations :
Departamento de Cirugía y Especialidades Médico-Quirúrgicas, Universidad de Oviedo, 33006 Oviedo, Spain.
Instituto Asturiano de Odontología, 33006 Oviedo, Spain.
Publications dans "Metalloproteases" :
4 publications dans cette catégorie
Affiliations :
Departamento de Bioquímica y Biología Molecular, Universidad de Oviedo, 33006 Oviedo, Spain.
Instituto Universitario de Oncología, IUOPA, Universidad de Oviedo, 33006 Oviedo, Spain.
Publications dans "Metalloproteases" :
3 publications dans cette catégorie
Affiliations :
Departamento de Biología Funcional, Área de Fisiología, Universidad de Oviedo, 33006 Oviedo, Spain.
Instituto Universitario de Oncología, IUOPA, Universidad de Oviedo, 33006 Oviedo, Spain.
Publications dans "Metalloproteases" :
3 publications dans cette catégorie
Affiliations :
Unit for Degradomics of the Protease Web, Biochemical Institute, University of Kiel, Kiel, Germany. cbeckerpauly@biochem.uni-kiel.de.
Publications dans "Metalloproteases" :
3 publications dans cette catégorie
Affiliations :
Department of Medical Biology, Faculty of Health Sciences, UiT-The Arctic University of Norway, 9037 Tromsø, Norway.
Publications dans "Metalloproteases" :
3 publications dans cette catégorie
Affiliations :
Department of Medical Biology, Faculty of Health Sciences, UiT-The Arctic University of Norway, 9037 Tromsø, Norway.
Publications dans "Metalloproteases" :
3 publications dans cette catégorie
Affiliations :
Department of Physics, Colorado School of Mines, 1500 Illinois Street, Golden, CO, 80401, USA.
Publications dans "Metalloproteases" :
3 publications dans cette catégorie
Affiliations :
Department of Physics, Colorado School of Mines, 1500 Illinois Street, Golden, CO, 80401, USA. ssarkar@mines.edu.
Publications dans "Metalloproteases" :
2 publications dans cette catégorie
Affiliations :
Department of Pathology, Otto-von-Guericke-University Magdeburg, Medical Faculty, Magdeburg, Germany. Electronic address: christoph.garbers@med.ovgu.de.
Publications dans "Metalloproteases" :
2 publications dans cette catégorie
Affiliations :
Department of Biology, East Carolina University, Greenville, NC 27858, USA. Electronic address: zhuy@ecu.edu.
Publications dans "Metalloproteases" :
2 publications dans cette catégorie
Affiliations :
Unit for Degradomics of the Protease Web, Biochemical Institute, University of Kiel, Kiel, Germany.
Publications dans "Metalloproteases" :
2 publications dans cette catégorie
Affiliations :
Neuroproteomics, School of Medicine, Klinikum rechts der Isar, Institute for Advanced Study, Technical University Munich, Munich, Germany.
Munich Center for Systems Neurology (SyNergy), Munich, Germany.
German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.
Publications dans "Metalloproteases" :
2 publications dans cette catégorie
Affiliations :
College of Biology and Pharmaceutical Engineering, Anhui Engineering Laboratory for Conservation and Sustainable Utilization of Traditional Chinese Medicine Resources, West Anhui University, Lu'an City 237012, China.
Publications dans "Metalloproteases" :
2 publications dans cette catégorie
Affiliations :
State Key Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Publications dans "Metalloproteases" :
2 publications dans cette catégorie
Affiliations :
State Key Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Publications dans "Metalloproteases" :
2 publications dans cette catégorie
Affiliations :
State Key Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Publications dans "Metalloproteases" :
2 publications dans cette catégorie
Affiliations :
State Key Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Publications dans "Metalloproteases" :
2 publications dans cette catégorie
Affiliations :
State Key Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Publications dans "Metalloproteases" :
Cognitive effort is thought to be familiar in everyday life, ubiquitous across multiple variations of task and circumstance, and integral to cost/benefit computations that are themselves central to th...
Seizures are common in dementia and associated with accelerated cognitive decline. However, the impact of active vs remote seizures on cognition remains understudied. This study aimed to investigate t...
This longitudinal, multicenter cohort is based on National Alzheimer's Coordinating Center data of participants recruited from 39 Alzheimer's Disease Centers in the United States from September 2005 t...
Of the 13,726 participants with normal cognition at enrollment (9,002 [66%] female; median age 71 years), 118 had active seizures and 226 had remote seizures. Of the 11,372 participants with MCI at en...
In this study, active seizures but not remote seizures were associated with earlier cognitive decline in both cognitively normal adults and those with MCI, independent of other dementia risk factors. ...
Genome-wide association studies have discovered common genetic variants associated with cognitive performance. Polygenic scores that summarize these discoveries explain up to 10% of the variance in co...
Considering the importance of cognitive and motor functions of the elderly people, the present study was conducted to evaluate the effectiveness of a cognitive exergame, called Neurolight compared to ...
A total of 36 individuals in the age range of 60 to 69 years were studied in the form of three groups: The control group continued their daily activities, while the Neurolight group underwent a cognit...
The results showed that cognitive-motor exercises using Neurolight, for 24 sessions, were able to significantly improve working memory, inhibitory control, and balance in individuals in this age group...
This finding supports the other studies suggesting combined cognitive and physical exercises for better effect. Based on its findings, the use of this exercise system can be suggested to coaches and t...
When making decisions, humans aim to maximize rewards while minimizing costs. The exertion of mental or physical effort has been proposed to be one those costs, translating into avoidance of behaviors...
The evaluation of cognitive functions interactions has become increasingly implemented in the cognition exploration. In the present study, we propose to examine the organization of the cognitive netwo...
In this editorial, the editors briefly introduce the aims of the Special Issue. If the goal of the scientific field of Cognitive Psychology is to improve our understanding of human cognition, then res...
The present article provides a unified systematic account of the role of cognitive control, motivation and dopamine pathways in relation to the development of fatigue. Since cognitive fatigue is consi...
Debate continues regarding the use of self- versus informant-report to diagnose mild cognitive impairment (MCI) with studies reporting patients both overestimating and underestimating their abilities ...
Three hundred six participants with MCI, and their informants, reported on cognitive decline; the participants also completed a comprehensive assessment of objective cognitive and functional performan...
Informant- but not self-reported cognitive decline significantly correlated with objective cognitive performance. There were 68 underestimators, 94 congruent estimators, and 144 overestimators. Undere...
We showed a poor concordance among self-report of cognitive decline and both informant-report of cognitive decline and cognitive performance in patients with MCI. Our findings highlight clinical and r...