Titre : Lactames macrocycliques

Lactames macrocycliques : Questions médicales fréquentes

Termes MeSH sélectionnés :

Correlation of Data
{ "@context": "https://schema.org", "@graph": [ { "@type": "MedicalWebPage", "name": "Lactames macrocycliques : Questions médicales les plus fréquentes", "headline": "Lactames macrocycliques : Comprendre les symptômes, diagnostics et traitements", "description": "Guide complet et accessible sur les Lactames macrocycliques : explications, diagnostics, traitements et prévention. Information médicale validée destinée aux patients.", "datePublished": "2024-07-19", "dateModified": "2025-04-15", "inLanguage": "fr", "medicalAudience": [ { "@type": "MedicalAudience", "name": "Grand public", "audienceType": "Patient", "healthCondition": { "@type": "MedicalCondition", "name": "Lactames macrocycliques" }, "suggestedMinAge": 18, "suggestedGender": "unisex" }, { "@type": "MedicalAudience", "name": "Médecins", "audienceType": "Physician", "geographicArea": { "@type": "AdministrativeArea", "name": "France" } }, { "@type": "MedicalAudience", "name": "Chercheurs", "audienceType": "Researcher", "geographicArea": { "@type": "AdministrativeArea", "name": "International" } } ], "reviewedBy": { "@type": "Person", "name": "Dr Olivier Menir", "jobTitle": "Expert en Médecine", "description": "Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale", "url": "/static/pages/docteur-olivier-menir.html", "alumniOf": { "@type": "EducationalOrganization", "name": "Université Paris Descartes" } }, "isPartOf": { "@type": "MedicalWebPage", "name": "Composés macrocycliques", "url": "https://questionsmedicales.fr/mesh/D047028", "about": { "@type": "MedicalCondition", "name": "Composés macrocycliques", "code": { "@type": "MedicalCode", "code": "D047028", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "D04.345" } } }, "hasPart": [ { "@type": "MedicalWebPage", "name": "Maitansine", "alternateName": "Maytansine", "url": "https://questionsmedicales.fr/mesh/D008453", "about": { "@type": "MedicalCondition", "name": "Maitansine", "code": { "@type": "MedicalCode", "code": "D008453", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "D04.345.295.500" } } }, { "@type": "MedicalWebPage", "name": "Rifamycine", "alternateName": "Rifamycins", "url": "https://questionsmedicales.fr/mesh/D012294", "about": { "@type": "MedicalCondition", "name": "Rifamycine", "code": { "@type": "MedicalCode", "code": "D012294", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "D04.345.295.750" } }, "hasPart": [ { "@type": "MedicalWebPage", "name": "Rifabutine", "alternateName": "Rifabutin", "url": "https://questionsmedicales.fr/mesh/D017828", "about": { "@type": "MedicalCondition", "name": "Rifabutine", "code": { "@type": "MedicalCode", "code": "D017828", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "D04.345.295.750.650" } }, "hasPart": [ { "@type": "MedicalWebPage", "name": "Streptovarycine", "alternateName": "Streptovaricin", "url": "https://questionsmedicales.fr/mesh/D013310", "about": { "@type": "MedicalCondition", "name": "Streptovarycine", "code": { "@type": "MedicalCode", "code": "D013310", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "D04.345.295.750.650.700" } } } ] }, { "@type": "MedicalWebPage", "name": "Streptovarycine", "alternateName": "Streptovaricin", "url": "https://questionsmedicales.fr/mesh/D013310", "about": { "@type": "MedicalCondition", "name": "Streptovarycine", "code": { "@type": "MedicalCode", "code": "D013310", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "D04.345.295.750.650.700" } } }, { "@type": "MedicalWebPage", "name": "Rifampicine", "alternateName": "Rifampin", "url": "https://questionsmedicales.fr/mesh/D012293", "about": { "@type": "MedicalCondition", "name": "Rifampicine", "code": { "@type": "MedicalCode", "code": "D012293", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "D04.345.295.750.700" } } }, { "@type": "MedicalWebPage", "name": "Rifaximine", "alternateName": "Rifaximin", "url": "https://questionsmedicales.fr/mesh/D000078262", "about": { "@type": "MedicalCondition", "name": "Rifaximine", "code": { "@type": "MedicalCode", "code": "D000078262", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "D04.345.295.750.850" } } } ] } ], "about": { "@type": "MedicalCondition", "name": "Lactames macrocycliques", "alternateName": "Lactams, Macrocyclic", "code": { "@type": "MedicalCode", "code": "D047029", "codingSystem": "MeSH" } }, "author": [ { "@type": "Person", "name": "Jonathan L Sessler", "url": "https://questionsmedicales.fr/author/Jonathan%20L%20Sessler", "affiliation": { "@type": "Organization", "name": "Department of Chemistry, The University of Texas at Austin, Austin, Texas 78712-1224, United States." } }, { "@type": "Person", "name": "Chunju Li", "url": "https://questionsmedicales.fr/author/Chunju%20Li", "affiliation": { "@type": "Organization", "name": "College of Sciences, Center for Supramolecular Chemistry and Catalysis, Shanghai University, Shanghai, 200444, People's Republic of China. cjli@shu.edu.cn." } }, { "@type": "Person", "name": "Zhongzhen Yang", "url": "https://questionsmedicales.fr/author/Zhongzhen%20Yang", "affiliation": { "@type": "Organization", "name": "Department of Chemistry, University of York, Heslington York YO10 5DD UK William.unsworth@york.ac.uk." } }, { "@type": "Person", "name": "Adrian C Whitwood", "url": "https://questionsmedicales.fr/author/Adrian%20C%20Whitwood", "affiliation": { "@type": "Organization", "name": "Department of Chemistry, University of York, Heslington York YO10 5DD UK William.unsworth@york.ac.uk." } }, { "@type": "Person", "name": "William P Unsworth", "url": "https://questionsmedicales.fr/author/William%20P%20Unsworth", "affiliation": { "@type": "Organization", "name": "Department of Chemistry, University of York, Heslington York YO10 5DD UK William.unsworth@york.ac.uk." } } ], "citation": [ { "@type": "ScholarlyArticle", "name": "Validity of muscular fitness self-assessments in the ecofit smartphone application: A correlation study.", "datePublished": "2022-12-01", "url": "https://questionsmedicales.fr/article/36454865", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.1371/journal.pone.0278374" } }, { "@type": "ScholarlyArticle", "name": "Correlation study between multiplanar reconstruction trigeminal nerve angulation and trigeminal neuralgia.", "datePublished": "2022-10-12", "url": "https://questionsmedicales.fr/article/36224533", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.1186/s12883-022-02906-9" } }, { "@type": "ScholarlyArticle", "name": "Preoperative proteinuria correlates with renal function after partial nephrectomy for renal cell carcinoma.", "datePublished": "2024-06-20", "url": "https://questionsmedicales.fr/article/38900287", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.1007/s00345-024-05042-w" } }, { "@type": "ScholarlyArticle", "name": "Correlation study of FGF23/D-serine in maintenance hemodialysis patients with combined hearing impairment.", "datePublished": "2023-01-17", "url": "https://questionsmedicales.fr/article/36649363", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.1371/journal.pone.0280378" } }, { "@type": "ScholarlyArticle", "name": "Prognostic and immune correlation analysis of mitochondrial autophagy and aging-related genes in lung adenocarcinoma.", "datePublished": "2023-09-12", "url": "https://questionsmedicales.fr/article/37698683", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.1007/s00432-023-05390-x" } } ], "breadcrumb": { "@type": "BreadcrumbList", "itemListElement": [ { "@type": "ListItem", "position": 1, "name": "questionsmedicales.fr", "item": "https://questionsmedicales.fr" }, { "@type": "ListItem", "position": 2, "name": "Composés polycycliques", "item": "https://questionsmedicales.fr/mesh/D011083" }, { "@type": "ListItem", "position": 3, "name": "Composés macrocycliques", "item": "https://questionsmedicales.fr/mesh/D047028" }, { "@type": "ListItem", "position": 4, "name": "Lactames macrocycliques", "item": "https://questionsmedicales.fr/mesh/D047029" } ] } }, { "@type": "MedicalWebPage", "name": "Article complet : Lactames macrocycliques - Questions et réponses", "headline": "Questions et réponses médicales fréquentes sur Lactames macrocycliques", "description": "Une compilation de questions et réponses structurées, validées par des experts médicaux.", "datePublished": "2025-05-05", "inLanguage": "fr", "hasPart": [ { "@type": "MedicalWebPage", "name": "Diagnostic", "headline": "Diagnostic sur Lactames macrocycliques", "description": "Comment diagnostiquer une infection bactérienne ?\nQuels tests sont utilisés pour les lactames macrocycliques ?\nQuels symptômes indiquent une infection nécessitant des lactames ?\nComment évaluer l'efficacité des lactames macrocycliques ?\nQuels examens d'imagerie sont utiles ?", "url": "https://questionsmedicales.fr/mesh/D047029?mesh_terms=Correlation+of+Data&page=2#section-diagnostic" }, { "@type": "MedicalWebPage", "name": "Symptômes", "headline": "Symptômes sur Lactames macrocycliques", "description": "Quels sont les symptômes d'une infection bactérienne ?\nLes lactames provoquent-ils des effets secondaires ?\nComment reconnaître une réaction allergique ?\nQuels signes d'infection nécessitent une attention médicale ?\nLes lactames macrocycliques affectent-ils le système digestif ?", "url": "https://questionsmedicales.fr/mesh/D047029?mesh_terms=Correlation+of+Data&page=2#section-symptômes" }, { "@type": "MedicalWebPage", "name": "Prévention", "headline": "Prévention sur Lactames macrocycliques", "description": "Comment prévenir les infections bactériennes ?\nLes lactames macrocycliques sont-ils utilisés en prophylaxie ?\nQuelles mesures d'hygiène sont recommandées ?\nLes vaccinations aident-elles contre les infections ?\nComment éviter la résistance aux antibiotiques ?", "url": "https://questionsmedicales.fr/mesh/D047029?mesh_terms=Correlation+of+Data&page=2#section-prévention" }, { "@type": "MedicalWebPage", "name": "Traitements", "headline": "Traitements sur Lactames macrocycliques", "description": "Comment les lactames macrocycliques sont-ils administrés ?\nQuel est le mécanisme d'action des lactames ?\nCombien de temps dure un traitement typique ?\nQuels antibiotiques sont des lactames macrocycliques ?\nComment gérer les effets secondaires des lactames ?", "url": "https://questionsmedicales.fr/mesh/D047029?mesh_terms=Correlation+of+Data&page=2#section-traitements" }, { "@type": "MedicalWebPage", "name": "Complications", "headline": "Complications sur Lactames macrocycliques", "description": "Quelles complications peuvent survenir avec les lactames ?\nComment gérer une surinfection ?\nLes lactames peuvent-ils causer des troubles rénaux ?\nQuels sont les signes d'une réaction sévère ?\nLes lactames macrocycliques peuvent-ils interagir avec d'autres médicaments ?", "url": "https://questionsmedicales.fr/mesh/D047029?mesh_terms=Correlation+of+Data&page=2#section-complications" }, { "@type": "MedicalWebPage", "name": "Facteurs de risque", "headline": "Facteurs de risque sur Lactames macrocycliques", "description": "Quels facteurs augmentent le risque d'infection ?\nLes antécédents d'allergies influencent-ils le traitement ?\nLe mode de vie affecte-t-il le risque d'infection ?\nLes personnes âgées sont-elles plus à risque ?\nLes voyages augmentent-ils le risque d'infections ?", "url": "https://questionsmedicales.fr/mesh/D047029?mesh_terms=Correlation+of+Data&page=2#section-facteurs de risque" } ] }, { "@type": "FAQPage", "mainEntity": [ { "@type": "Question", "name": "Comment diagnostiquer une infection bactérienne ?", "position": 1, "acceptedAnswer": { "@type": "Answer", "text": "Le diagnostic repose sur des cultures bactériennes et des tests de sensibilité." } }, { "@type": "Question", "name": "Quels tests sont utilisés pour les lactames macrocycliques ?", "position": 2, "acceptedAnswer": { "@type": "Answer", "text": "Des tests de sensibilité aux antibiotiques sont effectués pour évaluer l'efficacité." } }, { "@type": "Question", "name": "Quels symptômes indiquent une infection nécessitant des lactames ?", "position": 3, "acceptedAnswer": { "@type": "Answer", "text": "Fièvre, douleur, inflammation et signes d'infection localisée peuvent indiquer une infection." } }, { "@type": "Question", "name": "Comment évaluer l'efficacité des lactames macrocycliques ?", "position": 4, "acceptedAnswer": { "@type": "Answer", "text": "L'efficacité est évaluée par l'amélioration clinique et la réduction des cultures positives." } }, { "@type": "Question", "name": "Quels examens d'imagerie sont utiles ?", "position": 5, "acceptedAnswer": { "@type": "Answer", "text": "Des radiographies ou IRM peuvent être utilisées pour évaluer des infections profondes." } }, { "@type": "Question", "name": "Quels sont les symptômes d'une infection bactérienne ?", "position": 6, "acceptedAnswer": { "@type": "Answer", "text": "Fièvre, frissons, douleur, rougeur et gonflement au site d'infection sont fréquents." } }, { "@type": "Question", "name": "Les lactames provoquent-ils des effets secondaires ?", "position": 7, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des effets secondaires comme des éruptions cutanées ou des troubles gastro-intestinaux peuvent survenir." } }, { "@type": "Question", "name": "Comment reconnaître une réaction allergique ?", "position": 8, "acceptedAnswer": { "@type": "Answer", "text": "Des démangeaisons, un gonflement ou des difficultés respiratoires peuvent indiquer une allergie." } }, { "@type": "Question", "name": "Quels signes d'infection nécessitent une attention médicale ?", "position": 9, "acceptedAnswer": { "@type": "Answer", "text": "Une fièvre élevée persistante ou des douleurs intenses doivent être évaluées par un médecin." } }, { "@type": "Question", "name": "Les lactames macrocycliques affectent-ils le système digestif ?", "position": 10, "acceptedAnswer": { "@type": "Answer", "text": "Oui, ils peuvent causer des nausées, vomissements ou diarrhées chez certains patients." } }, { "@type": "Question", "name": "Comment prévenir les infections bactériennes ?", "position": 11, "acceptedAnswer": { "@type": "Answer", "text": "Une bonne hygiène, des vaccinations et un usage prudent des antibiotiques aident à prévenir." } }, { "@type": "Question", "name": "Les lactames macrocycliques sont-ils utilisés en prophylaxie ?", "position": 12, "acceptedAnswer": { "@type": "Answer", "text": "Oui, ils peuvent être utilisés en prophylaxie pour prévenir des infections post-chirurgicales." } }, { "@type": "Question", "name": "Quelles mesures d'hygiène sont recommandées ?", "position": 13, "acceptedAnswer": { "@type": "Answer", "text": "Se laver les mains régulièrement et éviter le contact avec des personnes malades sont essentiels." } }, { "@type": "Question", "name": "Les vaccinations aident-elles contre les infections ?", "position": 14, "acceptedAnswer": { "@type": "Answer", "text": "Oui, certaines vaccinations peuvent réduire le risque d'infections bactériennes spécifiques." } }, { "@type": "Question", "name": "Comment éviter la résistance aux antibiotiques ?", "position": 15, "acceptedAnswer": { "@type": "Answer", "text": "Utiliser les antibiotiques uniquement lorsque nécessaire et suivre les prescriptions médicales." } }, { "@type": "Question", "name": "Comment les lactames macrocycliques sont-ils administrés ?", "position": 16, "acceptedAnswer": { "@type": "Answer", "text": "Ils peuvent être administrés par voie intraveineuse ou orale, selon l'infection." } }, { "@type": "Question", "name": "Quel est le mécanisme d'action des lactames ?", "position": 17, "acceptedAnswer": { "@type": "Answer", "text": "Ils inhibent la synthèse de la paroi cellulaire bactérienne, entraînant la mort des bactéries." } }, { "@type": "Question", "name": "Combien de temps dure un traitement typique ?", "position": 18, "acceptedAnswer": { "@type": "Answer", "text": "La durée du traitement varie, mais elle est généralement de 7 à 14 jours selon l'infection." } }, { "@type": "Question", "name": "Quels antibiotiques sont des lactames macrocycliques ?", "position": 19, "acceptedAnswer": { "@type": "Answer", "text": "Des exemples incluent la méropénème et l'imipénème, utilisés pour des infections graves." } }, { "@type": "Question", "name": "Comment gérer les effets secondaires des lactames ?", "position": 20, "acceptedAnswer": { "@type": "Answer", "text": "Il est important de signaler tout effet indésirable au médecin pour ajuster le traitement." } }, { "@type": "Question", "name": "Quelles complications peuvent survenir avec les lactames ?", "position": 21, "acceptedAnswer": { "@type": "Answer", "text": "Des réactions allergiques graves ou des infections secondaires peuvent survenir." } }, { "@type": "Question", "name": "Comment gérer une surinfection ?", "position": 22, "acceptedAnswer": { "@type": "Answer", "text": "Une évaluation médicale est nécessaire pour ajuster le traitement et cibler la nouvelle infection." } }, { "@type": "Question", "name": "Les lactames peuvent-ils causer des troubles rénaux ?", "position": 23, "acceptedAnswer": { "@type": "Answer", "text": "Oui, certains lactames peuvent affecter la fonction rénale, nécessitant une surveillance." } }, { "@type": "Question", "name": "Quels sont les signes d'une réaction sévère ?", "position": 24, "acceptedAnswer": { "@type": "Answer", "text": "Des symptômes comme des difficultés respiratoires ou un gonflement du visage nécessitent une urgence." } }, { "@type": "Question", "name": "Les lactames macrocycliques peuvent-ils interagir avec d'autres médicaments ?", "position": 25, "acceptedAnswer": { "@type": "Answer", "text": "Oui, ils peuvent interagir avec d'autres médicaments, il est donc important d'informer le médecin." } }, { "@type": "Question", "name": "Quels facteurs augmentent le risque d'infection ?", "position": 26, "acceptedAnswer": { "@type": "Answer", "text": "L'immunodépression, le diabète et les interventions chirurgicales augmentent le risque." } }, { "@type": "Question", "name": "Les antécédents d'allergies influencent-ils le traitement ?", "position": 27, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des antécédents d'allergies aux antibiotiques peuvent limiter les options de traitement." } }, { "@type": "Question", "name": "Le mode de vie affecte-t-il le risque d'infection ?", "position": 28, "acceptedAnswer": { "@type": "Answer", "text": "Oui, un mode de vie sédentaire et une mauvaise alimentation peuvent augmenter le risque." } }, { "@type": "Question", "name": "Les personnes âgées sont-elles plus à risque ?", "position": 29, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les personnes âgées ont un système immunitaire affaibli, les rendant plus vulnérables." } }, { "@type": "Question", "name": "Les voyages augmentent-ils le risque d'infections ?", "position": 30, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les voyages peuvent exposer à des agents pathogènes inconnus, augmentant le risque d'infection." } } ] } ] }

Sources (10000 au total)

Validity of muscular fitness self-assessments in the ecofit smartphone application: A correlation study.

Mobile app-based interventions have the potential for wide-reach and therefore may be a useful tool in up-scaling physical activity interventions. In larger-scale interventions, face-to-face assessmen... This study compared baseline data from two muscular fitness tests from the ecofit two-armed randomised controlled trial and self-assessed data collected via the ecofit smartphone app (i.e., validated ... Participants (N = 54) completed the push-up (24.1%) and sit-to-stand (100%) tests within 14-days of receiving the app. The results revealed a strong significant correlation for the push-up test (0.83,... This study provides support for the concurrent validity of self-reported upper and lower body muscular fitness assessments (i.e., the push-up and sit-to-stand tests) in mHealth. While these tests may ...

Correlation study between multiplanar reconstruction trigeminal nerve angulation and trigeminal neuralgia.

Neurovascular compression (NVC) produces morphological changes on the trigeminal nerve root is considered the cause of trigeminal neuralgia (TN), but there were some patients with TN found no NVC, and... Patients with classical symptoms of TN were recruited as observation group (OG) in this study, 50 healthy controls were enrolled as control group (CG), the OG was further subtyped into young patients ... Ultimately, 95 patients with primary TN were recruited in OG, aged from 25 to 84 (61.15 ± 12.70) years with a course of 0.5 to 30 (5.03 ± 5.41) years, their onset age ranged from 24 to 82 (56.13 ± 11.... This study suggested that TNA might play a role in TN, small TNA could be a risk factor of TN. Furthermore, patients with small TNA are more likely to combine with TM, but more studies are needed to e...

Preoperative proteinuria correlates with renal function after partial nephrectomy for renal cell carcinoma.

Preoperative proteinuria is a prognostic factor of chronic kidney disease (CKD). We assessed the association between preoperative proteinuria and postoperative renal function after partial nephrectomy... We retrospectively reviewed our records of patients with a single malignant renal mass who underwent PN between 2000 and 2021. Patients with data on preoperative proteinuria were included. Baseline ch... Two hundred ninety-five patients were included. Twenty-two of them had preoperative proteinuria. No differences of age, smoking status, hypertension or diabetes, tumor size and use of ischemia were ob... Preoperative eGFR is the only independent predictor of long-term renal function after PN. Preoperative proteinuria correlates with renal function at 12 months. Proteinuria should be assessed before PN...

Correlation study of FGF23/D-serine in maintenance hemodialysis patients with combined hearing impairment.

Recent studies have reported an association between chronic renal failure and hearing impairment. Yet, the exact mechanism of action is still not fully understood. In this study, we investigated the e... A total of 90 subjects, including 30 MHD patients complicated with hearing impairment, 30 MHD patients with normal hearing, and 30 controls, were included in this case-control study. Relevant data wer... MHD patients showed abnormally high expression of FGF23 and D-serine, where FGF23 and D-serine levels were significantly higher in the group with hearing impairment than in the group with normal heari... This study provides potential biomarkers for the early detection of hearing impairment complicated by chronic renal failure, and the reduction of FGF23/D-serine may provide a potential target for the ...

Prognostic and immune correlation analysis of mitochondrial autophagy and aging-related genes in lung adenocarcinoma.

Mitophagy and aging (MiAg) are very important pathophysiological mechanisms contributing to tumorigenesis. MiAg-related genes have prognostic value in lung adenocarcinoma (LUAD). However, prognostic, ... MiAg differentially expressed genes (DEGs) in LUAD were obtained from public sequencing datasets. A prognostic model including MiAg DEGs was constructed according to patients divided into low- and hig... Seven MiAg DEGs of LUAD were identified: CAV1, DSG2, DSP, MYH11, NME1, PAICS, PLOD2, and the expression levels of these genes were significantly correlated (P < 0.05). The RiskScore of the MiAg DEG pr... Seven MiAg-related genes were identified to be significantly associated with the prognosis of patients diagnosed with LUAD. Moreover, the identified MiAg DEGs might affect the immunotherapy strategy o...

Self-reported medication administration errors in clinical practice of nurses: a descriptive correlation study.

Medication administration errors (MAE) are a worldwide issue affecting the safety of hospitalized patients. Through the early identification of potential causes, it is possible to increase the safety ... A descriptive correlation study through a non-standardized questionnaire was used. Data were collected from September 29 to October 15, 2021, from nurses in the Czech Republic. For statistical analysi... The research sample consisted of 1205 nurses. The authors found that there was a statistically significant relationship between nurse education (p = 0.05), interruptions, preparation of medicines outs... The results of the study point to the weaknesses of medication administration in selected clinical departments in hospitals. The authors found that several factors, such as high patient ratio per nurs...

Correlation Analysis and Prognostic Impacts of Biological Characteristics in Elderly Patients with Acute Myeloid Leukemia.

The significant heterogeneity of elderly AML patients' biological features has caused stratification difficulties and adverse prognosis. This paper did a correlation study between their genetic mutati... 90 newly diagnosed elderly acute myeloid leukemia (AML) patients (aged ≥60 years) who detected genetic mutations by next-generation sequencing (NGS) were enrolled between April 2015 and March 2021 in ... A total of 29 genetic mutations were identified in 82 patients among 90 cases with a frequency of 91.1%. DNMT3A, BCOR, U2AF1, and BCORL1 mutations were unevenly distributed among different FAB classif... The study showed specific correlations between elderly AML patients' genetic mutations and clinical features, some of which may impact prognosis....

Correlation study of male semen parameters and embryo aneuploidy in preimplantation genetic testing for aneuploidy.

The purpose of this study was to evaluate the influence of abnormal semen parameters on embryo aneuploidy based on single nucleotide polymorphism microarray (SNP array).... A total of 464 blastocysts from 103 PGT-A cycles were analyzed. The embryo quality and embryo aneuploidy rates were compared between different groups which divided by male semen parameters (sperm conc... The total blastocysts chromosome aneuploidy rate was 42.3% (191/452). In the teratozoospermia group, the good-quality embryo and blastocyst formation rate were lower than the normal group(44.4% vs 60.... Our study revealed that sperm DFI were positively correlated with blastocyst aneuploidy rate, while sperm motility and sperm morphology rate were negatively correlated with blastocyst aneuploidy rate....