questionsmedicales.fr
Phénomènes physiologiques cellulaires
Cycle cellulaire
Cytocinèse
Cytocinèse : Questions médicales fréquentes
Termes MeSH sélectionnés :
Diagnostic
5
Cytocinèse
Anomalies chromosomiques
Cytocinèse
Marqueurs cellulaires
Cytocinèse
Anomalies cellulaires
Symptômes
5
Cytocinèse
Cellules géantes
Cytocinèse
Croissance cellulaire
Cytocinèse
Malformations tissulaires
Cytocinèse
Cycle cellulaire
Prévention
5
Cytocinèse
Infections virales
Traitements
5
Cytocinèse
Chimiothérapie
Cytocinèse
Thérapie génique
Cytocinèse
Thérapie génique
Cytocinèse
Recherche médicale
Complications
5
Cytocinèse
Développement embryonnaire
Cytocinèse
Cancer du sein
Cytocinèse
Système immunitaire
Facteurs de risque
5
Cytocinèse
Facteurs génétiques
Cytocinèse
Habitudes alimentaires
Cytocinèse
Expositions professionnelles
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"@type": "Question",
"name": "Comment diagnostiquer une anomalie de cytocinèse ?",
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"text": "Des tests de microscopie et des analyses génétiques peuvent révéler des anomalies."
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{
"@type": "Question",
"name": "Quels examens sont utilisés pour étudier la cytocinèse ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "La microscopie à fluorescence et l'immunofluorescence sont couramment utilisées."
}
},
{
"@type": "Question",
"name": "Quels marqueurs cellulaires indiquent une cytocinèse réussie ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "La présence de structures comme le sillon de division et les corps de Golgi est observée."
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{
"@type": "Question",
"name": "Peut-on observer la cytocinèse au microscope ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, la cytocinèse est visible au microscope lors de la division cellulaire."
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"@type": "Question",
"name": "Quels sont les signes d'une cytocinèse défectueuse ?",
"position": 5,
"acceptedAnswer": {
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"text": "Des cellules multinucleées ou des anomalies morphologiques peuvent indiquer des problèmes."
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{
"@type": "Question",
"name": "Quels symptômes indiquent une défaillance de la cytocinèse ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des cellules anormales, comme des cellules géantes, peuvent être observées."
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{
"@type": "Question",
"name": "La cytocinèse affecte-t-elle la croissance cellulaire ?",
"position": 7,
"acceptedAnswer": {
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{
"@type": "Question",
"name": "Quels effets sur les tissus peuvent résulter d'une mauvaise cytocinèse ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Cela peut entraîner des malformations tissulaires et des troubles fonctionnels."
}
},
{
"@type": "Question",
"name": "Y a-t-il des symptômes associés à des troubles de la cytocinèse ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des troubles comme le cancer peuvent être liés à des anomalies de la cytocinèse."
}
},
{
"@type": "Question",
"name": "Comment la cytocinèse influence-t-elle le cycle cellulaire ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elle est essentielle pour terminer le cycle cellulaire et permettre la division."
}
},
{
"@type": "Question",
"name": "Peut-on prévenir les troubles de la cytocinèse ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une bonne santé cellulaire et des habitudes de vie saines peuvent aider à prévenir."
}
},
{
"@type": "Question",
"name": "Quels facteurs de style de vie influencent la cytocinèse ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une alimentation équilibrée et l'exercice régulier favorisent la santé cellulaire."
}
},
{
"@type": "Question",
"name": "Les toxines environnementales affectent-elles la cytocinèse ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'exposition à certaines toxines peut perturber la cytocinèse."
}
},
{
"@type": "Question",
"name": "Comment le stress influence-t-il la cytocinèse ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le stress chronique peut affecter la division cellulaire et la cytocinèse."
}
},
{
"@type": "Question",
"name": "Les infections peuvent-elles perturber la cytocinèse ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines infections virales peuvent interférer avec le processus de cytocinèse."
}
},
{
"@type": "Question",
"name": "Quels traitements existent pour les troubles de la cytocinèse ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les traitements ciblent souvent les causes sous-jacentes, comme la chimiothérapie."
}
},
{
"@type": "Question",
"name": "Peut-on corriger les anomalies de la cytocinèse ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines anomalies peuvent être corrigées par des thérapies géniques expérimentales."
}
},
{
"@type": "Question",
"name": "Quels médicaments affectent la cytocinèse ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des agents comme la colchicine peuvent perturber la cytocinèse en bloquant la mitose."
}
},
{
"@type": "Question",
"name": "La thérapie génique peut-elle aider la cytocinèse ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elle peut corriger certaines mutations affectant la cytocinèse."
}
},
{
"@type": "Question",
"name": "Comment la recherche aide-t-elle à traiter les troubles de la cytocinèse ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "La recherche explore de nouvelles cibles thérapeutiques pour améliorer la cytocinèse."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent résulter d'une cytocinèse défectueuse ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des complications incluent des cancers, des malformations et des troubles métaboliques."
}
},
{
"@type": "Question",
"name": "Comment la cytocinèse affecte-t-elle le développement embryonnaire ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une cytocinèse anormale peut entraîner des malformations congénitales."
}
},
{
"@type": "Question",
"name": "Les troubles de la cytocinèse sont-ils héréditaires ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines anomalies peuvent être héréditaires, augmentant le risque de maladies."
}
},
{
"@type": "Question",
"name": "Quels cancers sont liés à des anomalies de la cytocinèse ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des cancers comme le cancer du sein et le cancer colorectal peuvent être liés."
}
},
{
"@type": "Question",
"name": "La cytocinèse défectueuse peut-elle affecter le système immunitaire ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elle peut compromettre la fonction immunitaire et augmenter les infections."
}
},
{
"@type": "Question",
"name": "Quels facteurs génétiques influencent la cytocinèse ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des mutations dans des gènes régulateurs peuvent augmenter le risque de troubles."
}
},
{
"@type": "Question",
"name": "L'âge est-il un facteur de risque pour la cytocinèse ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'âge avancé peut augmenter le risque d'anomalies dans la cytocinèse."
}
},
{
"@type": "Question",
"name": "Les habitudes alimentaires affectent-elles la cytocinèse ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une alimentation riche en antioxydants peut réduire les risques d'anomalies."
}
},
{
"@type": "Question",
"name": "Le tabagisme influence-t-il la cytocinèse ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le tabagisme est un facteur de risque connu pour des anomalies cellulaires."
}
},
{
"@type": "Question",
"name": "Les expositions professionnelles peuvent-elles affecter la cytocinèse ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines expositions à des produits chimiques peuvent perturber la cytocinèse."
}
}
]
}
]
}
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 20/04/2025
Contenu vérifié selon les dernières recommandations médicales
3 publications dans cette catégorie
Affiliations :
Laboratory of Biochemistry and Molecular Biology of Germ Cells, IAPG CAS, Libechov, Czech Republic.
Department of Cell Biology, Faculty of Science, Charles University, Prague, Czech Republic.
Publications dans "Cytocinèse" :
3 publications dans cette catégorie
Affiliations :
Laboratory of Biochemistry and Molecular Biology of Germ Cells, IAPG CAS, Libechov, Czech Republic.
Publications dans "Cytocinèse" :
3 publications dans cette catégorie
Affiliations :
Laboratory of Biochemistry and Molecular Biology of Germ Cells, IAPG CAS, Libechov, Czech Republic. susor@iapg.cas.cz.
Publications dans "Cytocinèse" :
2 publications dans cette catégorie
Affiliations :
Department of Molecular, Cellular and Developmental Biology, Department of Molecular Biophysics and Biochemistry, Department of Cell Biology, Yale University, New Haven, CT, USA. thomas.pollard@yale.edu.
Publications dans "Cytocinèse" :
2 publications dans cette catégorie
Affiliations :
Oncode Institute, Utrecht, Netherlands. s.m.a.lens@umcutrecht.nl.
Center for Molecular Medicine, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands. s.m.a.lens@umcutrecht.nl.
Publications dans "Cytocinèse" :
2 publications dans cette catégorie
Affiliations :
Department of Developmental Genetics, Center for Plant Molecular Biology, Eberhard-Karls-Universität Tübingen, 72076 Tübingen, Germany; email: panteleimon.livanos@zmbp.uni-tuebingen.de , sabine.mueller@zmbp.uni-tuebingen.de.
Publications dans "Cytocinèse" :
2 publications dans cette catégorie
Affiliations :
Cancer and Developmental Biology Laboratory, National Cancer Institute, Frederick, MD 21702, USA.
Publications dans "Cytocinèse" :
2 publications dans cette catégorie
Affiliations :
Cancer and Developmental Biology Laboratory, National Cancer Institute, Frederick, MD 21702, USA.
Publications dans "Cytocinèse" :
2 publications dans cette catégorie
Affiliations :
Department of Microbiology and Molecular Genetics, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, Texas, USA.
Publications dans "Cytocinèse" :
2 publications dans cette catégorie
Affiliations :
Department of Microbiology and Molecular Genetics, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, Texas, USA.
Publications dans "Cytocinèse" :
2 publications dans cette catégorie
Affiliations :
Department of Plant Sciences, University of California Davis, Davis, CA, USA.
Publications dans "Cytocinèse" :
2 publications dans cette catégorie
Affiliations :
Department of Cell Biology, Johns Hopkins School of Medicine, Baltimore, MD, United States.
Department of Pharmacology and Molecular Sciences, Johns Hopkins School of Medicine, Baltimore, MD, United States.
Department of Medicine, Johns Hopkins School of Medicine, Baltimore, MD, United States.
Department of Oncology, Johns Hopkins School of Medicine, Baltimore, MD, United States.
Chemical and Biomolecular Engineering, Johns Hopkins University Whiting School of Engineering, Baltimore, MD, United States.
Publications dans "Cytocinèse" :
2 publications dans cette catégorie
Affiliations :
Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QP, UK.
Publications dans "Cytocinèse" :
2 publications dans cette catégorie
Affiliations :
Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor.
Cellular and Molecular Biology Graduate Program, University of Michigan, Ann Arbor.
Publications dans "Cytocinèse" :
2 publications dans cette catégorie
Affiliations :
Biology Department, Concordia University, Montréal, QC, H4B 1R6, Canada.
Publications dans "Cytocinèse" :
2 publications dans cette catégorie
Affiliations :
Biology Department, Concordia University, Montréal, QC, H4B 1R6, Canada.
Center for Microscopy and Cellular Imaging, Concordia University, Montréal, QC, H4B 1R6, Canada.
Publications dans "Cytocinèse" :
2 publications dans cette catégorie
Affiliations :
Department of Biochemistry and Molecular Biology, The Institute of Medical Research Israel-Canada, The Hebrew University-Hadassah Medical School, Jerusalem 91120, Israel.
Publications dans "Cytocinèse" :
2 publications dans cette catégorie
Affiliations :
Department of Biochemistry and Molecular Biology, The Institute of Medical Research Israel-Canada, The Hebrew University-Hadassah Medical School, Jerusalem 91120, Israel.
Publications dans "Cytocinèse" :
2 publications dans cette catégorie
Affiliations :
Department of Biochemistry and Molecular Biology, The Institute of Medical Research Israel-Canada, The Hebrew University-Hadassah Medical School, Jerusalem 91120, Israel.
Publications dans "Cytocinèse" :
2 publications dans cette catégorie
Affiliations :
Department of Biochemistry and Molecular Biology, The Institute of Medical Research Israel-Canada, The Hebrew University-Hadassah Medical School, Jerusalem 91120, Israel shoshr@ekmd.huji.ac.il.
Publications dans "Cytocinèse" :
Perfusion weighted imaging (PWI) is critical for determining whether stroke patients presenting in an extended time window are candidates for mechanical thrombectomy. However, PWI is not always availa...
The National Institutes of Health (NIH) FHV score was developed to quantify the burden of FHV and applied to magnetic resonance imaging scans of stroke patients with fluid-attenuated inversion recover...
There were 101 patients included in the analysis, of whom 78% had a perfusion deficit detected on PWI with a mean lesion volume of 47 (±59) mL. The NIH-FHV score was strongly associated with the PWI l...
The NIH-FHV score provides an estimate of the PWI lesion volume and, when combined with diffusion weighted imaging, may be helpful when trying to determine whether there is a clinically relevant diffu...
Although hypothermic machine perfusion (HMP) is associated with improved kidney graft viability and function, the underlying biological mechanisms are unknown. Untargeted metabolomic profiling may ide...
This letter responds to the article "Neither Ethical nor Prudent: Why Not to Choose Normothermic Regional Perfusion," by Adam Omelianchuk et al., in the July-August 2024 issue of the Hastings Center R...
Type 2 diabetes mellitus (T2DM) is associated with altered cerebral vasoreactivity, cognitive impairment, and functional decline. Magnetic Resonance (MR) perfusion can be used to assess cerebral blood...
The study included 52 patients diagnosed with T2DM and 39 healthy individuals. The diabetic patients were classified into three groups (PRP: proliferative retinopathy, NPRP: non-proliferative retinopa...
The comparison between the T2DM group and the control group revealed that rCBF values of bilateral frontal lobes, cingulate gyrus, medial temporal lobe, thalami and right occipital lobe were measured ...
Regional hypoperfusion was encountered in most of the lobes in the T2DM group when compared with the healthy group. However, in terms of rCBF values, there was no significant difference among the thre...
Pulmonary blood flow can be assessed on ventilation-perfusion (VQ) scan with relative lung perfusion, with a 55% to 45% (or 10%) right-to-left differential considered normal. We hypothesized that wide...
We conducted a retrospective cohort study on all patients who underwent double-lung transplant in our program between 2005 and 2016, identifying patients with a wide perfusion differential of >10% on ...
Of 340 patients who met inclusion criteria, 169 (49%) had a relative perfusion differential of ≥ 10% on a 3-mo VQ scan. Patients with increased perfusion differential had increased risk of death or re...
Wide lung perfusion differential was common after lung transplant in our cohort and associated with increased risk of death, poor lung function, and CLAD onset. The nature of this abnormality and its ...
Although COVID-19 infection is associated with the increased risk of pulmonary thromboembolism (PTE), COVID-19 pulmonary lesions cause ventilation-perfusion (V/Q) patterns other than PTE. Although ext...
This article describes fabrication of a customizable bioreactor, which comprises a perfusion system and coverslip-based tissue culture chamber that allow centimeter-scale vascularized or otherwise can...
We aimed at examining both the incidence and extent of different lung perfusion abnormalities as well as the relationship between them on Tc-99m macroaggregated albumin (MAA) perfusion-only SPECT/CT s...
Ninety-one patients (71.4 ± 13.9 years; range: 29-98 years, median age: 74 years; 45 female and 46 male) with confirmed SARS-CoV-2 virus infection were included in this retrospective study. After perf...
Moderately severe parenchymal lesions were detected in 87 (95.6%) patients. Although, 50 (54.95%) patients were depicted to have MM lesions, the whole patient cohort was mildly affected by this abnorm...
Heterogeneous perfusion abnormalities were found in most of COVID-19 patients: parenchymal lesions with normal, decreased or increased perfusion and perfusion defects in healthy lung areas. These phen...
Liver transplantation is the only chance of cure for people with end-stage liver disease and some people with advanced liver cancers or acute liver failure. The increasing prevalence of these conditio...
To evaluate the effects of different methods of machine perfusion (including hypothermic oxygenated machine perfusion (HOPE), normothermic machine perfusion (NMP), controlled oxygenated rewarming, and...
We used standard, extensive Cochrane search methods. The latest search date was 10 January 2023....
We included randomised clinical trials which compared different methods of machine perfusion, either with each other or with SCS. Studies comparing HOPE via both hepatic artery and portal vein, or via...
We used standard Cochrane methods. Our primary outcomes were 1. overall participant survival, 2. quality of life, and 3. serious adverse events. Secondary outcomes were 4. graft survival, 5. ischaemic...
We included seven randomised trials (1024 transplant recipients from 1301 randomised/included livers). All trials were parallel two-group trials; four compared HOPE versus SCS, and three compared NMP ...
In situations where the decision has been made to transplant a liver donated after circulatory death or donated following brain death, end-ischaemic HOPE will provide superior clinically relevant outc...
The field of organ transplantation has been facing the problem of organ shortage for several years. It is even more crucial since the number of patients on the waiting list is growing steadily. There ...