questionsmedicales.fr
Acides aminés, peptides et protéines
Protéines
Protéines membranaires
Protéines de transport membranaire
Canaux ioniques
Canaux potassiques
Canaux potassiques voltage-dépendants
Canaux potassiques rectifiants retardés
Canaux potassiques KNCQ
Canal potassique KCNQ1
Canal potassique KCNQ1 : Questions médicales fréquentes
Termes MeSH sélectionnés :
Physical Functional Performance
Diagnostic
5
Canaux potassiques
Génétique médicale
Électrophysiologie
Tests génétiques
Antécédents familiaux
Troubles cardiaques
Cardiologie
Génétique médicale
Symptômes
5
Arythmies
Douleurs thoraciques
Activité physique
Surveillance médicale
Asymptomatique
Mutation génétique
Prévention
5
Surveillance médicale
Complications
Tests génétiques
Prévention
Éducation des patients
Gestion des symptômes
Activité physique
Évaluation médicale
Conseils diététiques
Santé cardiaque
Traitements
5
Médicaments antiarythmiques
Dispositifs médicaux
Chirurgie cardiaque
Arythmies
Mode de vie
Alimentation saine
Médecine personnalisée
Antécédents médicaux
Complications
5
Complications
Mort subite
Accidents vasculaires cérébraux
Arythmies
Réversibilité
Gestion des complications
Surveillance
Fonction cardiaque
Variabilité
Complications
Facteurs de risque
5
Facteurs de risque
Maladies cardiaques
Médicaments
Fonction cardiaque
Habitudes de vie
Complications
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"name": "Comment diagnostiquer une dysfonction du canal KCNQ1 ?",
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"@type": "Question",
"name": "Quels tests sont utilisés pour évaluer KCNQ1 ?",
"position": 2,
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"@type": "Question",
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"@type": "Question",
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"position": 6,
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"name": "Les symptômes de KCNQ1 varient selon l'âge ?",
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"@type": "Question",
"name": "Comment les symptômes de KCNQ1 affectent-ils la vie quotidienne ?",
"position": 8,
"acceptedAnswer": {
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}
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{
"@type": "Question",
"name": "Les symptômes de KCNQ1 sont-ils toujours présents ?",
"position": 9,
"acceptedAnswer": {
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"text": "Non, certains patients peuvent être asymptomatiques malgré une mutation."
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"name": "Les symptômes de KCNQ1 peuvent-ils s'aggraver avec le temps ?",
"position": 10,
"acceptedAnswer": {
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"text": "Oui, sans traitement, les symptômes peuvent s'aggraver avec l'âge."
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"@type": "Question",
"name": "Comment prévenir les complications liées à KCNQ1 ?",
"position": 11,
"acceptedAnswer": {
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"text": "La surveillance régulière et le traitement précoce sont essentiels."
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"@type": "Question",
"name": "Les tests génétiques aident-ils à la prévention de KCNQ1 ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les tests génétiques peuvent identifier les personnes à risque."
}
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{
"@type": "Question",
"name": "L'éducation des patients est-elle importante pour KCNQ1 ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, comprendre la maladie aide les patients à gérer leurs symptômes."
}
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"@type": "Question",
"name": "Les activités physiques sont-elles sûres pour les patients KCNQ1 ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Cela dépend de la gravité des symptômes; une évaluation médicale est nécessaire."
}
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{
"@type": "Question",
"name": "Les conseils diététiques peuvent-ils prévenir KCNQ1 ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une alimentation équilibrée peut contribuer à la santé cardiaque générale."
}
},
{
"@type": "Question",
"name": "Quels traitements sont disponibles pour les troubles KCNQ1 ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les traitements incluent des médicaments antiarythmiques et des dispositifs implantables."
}
},
{
"@type": "Question",
"name": "La chirurgie est-elle une option pour KCNQ1 ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, la chirurgie peut être envisagée dans les cas graves d'arythmies."
}
},
{
"@type": "Question",
"name": "Les changements de mode de vie aident-ils avec KCNQ1 ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, éviter le stress et adopter une alimentation saine peuvent aider."
}
},
{
"@type": "Question",
"name": "Les bêta-bloquants sont-ils efficaces pour KCNQ1 ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les bêta-bloquants peuvent aider à contrôler les arythmies."
}
},
{
"@type": "Question",
"name": "Les traitements sont-ils personnalisés pour KCNQ1 ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les traitements sont souvent adaptés en fonction des symptômes et des antécédents."
}
},
{
"@type": "Question",
"name": "Quelles sont les complications possibles de KCNQ1 ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les complications incluent des arythmies graves et un risque accru de mort subite."
}
},
{
"@type": "Question",
"name": "KCNQ1 peut-il entraîner des AVC ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des arythmies peuvent augmenter le risque d'accidents vasculaires cérébraux."
}
},
{
"@type": "Question",
"name": "Les complications de KCNQ1 sont-elles réversibles ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines complications peuvent être gérées, mais d'autres peuvent être permanentes."
}
},
{
"@type": "Question",
"name": "Comment les complications de KCNQ1 sont-elles surveillées ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elles sont surveillées par des examens réguliers et des tests de fonction cardiaque."
}
},
{
"@type": "Question",
"name": "Les complications de KCNQ1 varient-elles selon les individus ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, la gravité et le type de complications peuvent varier d'une personne à l'autre."
}
},
{
"@type": "Question",
"name": "Quels sont les facteurs de risque pour KCNQ1 ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les facteurs incluent des antécédents familiaux, des maladies cardiaques et des médicaments."
}
},
{
"@type": "Question",
"name": "L'âge est-il un facteur de risque pour KCNQ1 ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le risque augmente souvent avec l'âge, surtout chez les hommes."
}
},
{
"@type": "Question",
"name": "Le stress peut-il aggraver KCNQ1 ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le stress peut déclencher ou aggraver les symptômes d'arythmie."
}
},
{
"@type": "Question",
"name": "Les médicaments peuvent-ils influencer KCNQ1 ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certains médicaments peuvent interférer avec la fonction du canal KCNQ1."
}
},
{
"@type": "Question",
"name": "Les habitudes de vie affectent-elles KCNQ1 ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des habitudes de vie saines peuvent réduire le risque de complications."
}
}
]
}
]
}
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 08/03/2025
Contenu vérifié selon les dernières recommandations médicales
5 publications dans cette catégorie
Affiliations :
Department of Anesthesiology, Pharmacology & Therapeutics, The University of British Columbia, Vancouver, BC, Canada.
Publications dans "Canal potassique KCNQ1" :
5 publications dans cette catégorie
Affiliations :
Department of Anesthesiology, Pharmacology & Therapeutics, The University of British Columbia, Vancouver, BC, Canada.
Publications dans "Canal potassique KCNQ1" :
5 publications dans cette catégorie
Affiliations :
Laboratory of Intracellular Ion Channels, Nencki Institute of Experimental Biology, Polish Academy of Sciences, 02-093 Warsaw, Poland.
Publications dans "Canal potassique KCNQ1" :
4 publications dans cette catégorie
Affiliations :
Center for Structural Biology, Vanderbilt University, Nashville, Tennessee, United States of America.
Department of Chemistry, Vanderbilt University, Nashville, Tennessee, United States of America.
Publications dans "Canal potassique KCNQ1" :
4 publications dans cette catégorie
Affiliations :
Department of Pharmacology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America.
Publications dans "Canal potassique KCNQ1" :
4 publications dans cette catégorie
Affiliations :
Center for Structural Biology, Vanderbilt University, Nashville, Tennessee, United States of America.
Department of Biochemistry, Vanderbilt University, Nashville, Tennessee, United States of America.
Publications dans "Canal potassique KCNQ1" :
4 publications dans cette catégorie
Affiliations :
Center for Structural Biology, Vanderbilt University, Nashville, Tennessee, United States of America.
Department of Chemistry, Vanderbilt University, Nashville, Tennessee, United States of America.
Department of Pharmacology, Vanderbilt University, Nashville, Tennessee, United States of America.
Publications dans "Canal potassique KCNQ1" :
4 publications dans cette catégorie
Affiliations :
Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, VIC 3052, Australia; ARC Centre for Fragment-Based Design, Monash University, Parkville, VIC 3052, Australia. Electronic address: ray.norton@monash.edu.
Publications dans "Canal potassique KCNQ1" :
4 publications dans cette catégorie
Affiliations :
Laboratory of Intracellular Ion Channels, Nencki Institute of Experimental Biology, Polish Academy of Sciences, Pasteura 3, 02-093 Warsaw, Poland.
Publications dans "Canal potassique KCNQ1" :
3 publications dans cette catégorie
Affiliations :
Department of Pharmacology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America.
Publications dans "Canal potassique KCNQ1" :
3 publications dans cette catégorie
Affiliations :
Department of Physiology and Biophysics, University of Miami, Miami, FL.
Publications dans "Canal potassique KCNQ1" :
3 publications dans cette catégorie
Affiliations :
Bioelectricity Laboratory, Department of Physiology and Biophysics, School of Medicine, University of California, Irvine, California.
Publications dans "Canal potassique KCNQ1" :
3 publications dans cette catégorie
Affiliations :
Laboratory of Intracellular Ion Channels, Nencki Institute of Experimental Biology, Polish Academy of Sciences, 02-093 Warsaw, Poland.
Publications dans "Canal potassique KCNQ1" :
2 publications dans cette catégorie
Affiliations :
Center for Structural Biology, Vanderbilt University, Nashville, Tennessee, United States of America.
Department of Chemistry, Vanderbilt University, Nashville, Tennessee, United States of America.
Publications dans "Canal potassique KCNQ1" :
2 publications dans cette catégorie
Affiliations :
Center for Structural Biology, Vanderbilt University, Nashville, Tennessee, United States of America.
Department of Biochemistry, Vanderbilt University, Nashville, Tennessee, United States of America.
Publications dans "Canal potassique KCNQ1" :
2 publications dans cette catégorie
Affiliations :
Department of Biochemistry and Molecular Biology, The University of Texas Health Science Center, Houston, TX 77030, USA.
Publications dans "Canal potassique KCNQ1" :
2 publications dans cette catégorie
Affiliations :
Cell, Molecular, and Structural Biology Program, Department of Chemistry & Biochemistry, Miami University, Oxford, OH 45056, USA; Department of Chemistry and Biochemistry, Miami University, Oxford, OH 45056, USA.
Publications dans "Canal potassique KCNQ1" :
2 publications dans cette catégorie
Affiliations :
Cell, Molecular, and Structural Biology Program, Department of Chemistry & Biochemistry, Miami University, Oxford, OH 45056, USA; Department of Chemistry and Biochemistry, Miami University, Oxford, OH 45056, USA. Electronic address: gary.lorigan@miamioh.edu.
Publications dans "Canal potassique KCNQ1" :
2 publications dans cette catégorie
Affiliations :
Department of Anesthesiology, Pharmacology & Therapeutics, The University of British Columbia, Vancouver, BC, Canada.
Publications dans "Canal potassique KCNQ1" :
2 publications dans cette catégorie
Affiliations :
Laboratory of Computational Modeling of Biological Processes, Institute of Molecular Biology of National Academy of Sciences of the Republic of Armenia , Yerevan, Armenia.
Publications dans "Canal potassique KCNQ1" :
Falls among older adults have become a global concern. While previous studies have established associations between autonomic function indicator; heart rate variability (HRV) and blood pressure variab...
In this cross-sectional survey, adults aged ≥ 60 years were recruited. Continuous non-invasive BP was monitored over 5 min of supine and 3 min of standing. Psychological status was assessed in terms o...
A total of 62 participants were recruited consisting of 37 fallers and 25 non-fallers. Multivariate analysis revealed that Lawton IADL was independently associated with systolic blood pressure variabi...
Our findings suggest that fallers had poorer ANS, greater dependence in IADLs, and were more anxious. IADL dependency and anxiety were the most predictive of autonomic dysfunction, and can be used in ...
Multiple sclerosis (MS) typically has its onset in early and middle adulthood, but the population is steadily becoming more dominated by older adults. One of the primary consequences of both MS and ag...
The study involved secondary analysis of cross-sectional data from multiple studies. Ambulatory adults with MS who were relapse-free for the last 30 days were recruited, and controls were recruited ba...
The two-way ANOVA indicated a main effect of MS status (F(5,500)=34.74, p<.01, η...
Overall, MS status and aging have additive effects on physical function, and the summary SPPB score may be driven by a specific component within each age group. SPPB scores may be driven more by mobil...
To investigate whether a multi-item performance outcome measure, the physical performance test (PPT), can be calibrated to a common scale with patient-reported outcome measures, using the Patient-Repo...
We analyzed baseline data (N = 1,113) from the CONVINCE study, an international trial in end-stage kidney disease patients comparing high-dose hemodiafiltration with high-flux hemodialysis. Assumption...
Although some evidence for multidimensionality was found, classical test statistics (Cronbach's Alpha = 0.93), Mokken (Loevinger's H = 0.50), and bifactor analysis (explained common variance = 0.65) i...
We found preliminary evidence that the PPT can be linked to the PROMIS PF metric in hemodialysis patients, enabling group comparisons across patient-reported outcome and performance outcome measures. ...
Children with Juvenile Idiopathic Arthritis (JIA) may adopt different movement patterns and participate in physical activity during different states of disease....
Which specific features of gait and physical function performance differ among children with active or inactive JIA compared to healthy children?...
Forty-three children participated (14.5 ± 4.2 yrs; 60 % female). 3D-motion analysis methods were coupled with force measures from an instrumented treadmill captured gait mechanical measures. The 30-se...
Compared to healthy controls children with active and inactive JIA had worse outcomes (12-21 % slower self-selected and fast walking speeds, 28-34 % slower stair navigation times, 28 % fewer chair ris...
Gait speed, specific load-bearing functional tasks and leg stiffness features of gait may be informative 'functional biomarkers' for assessing JIA burden and tracking treatment efficacy. Additional pr...
The aim of this study was twofold: (i) to observe the individual results of fitness status [countermovement jump (CMJ)], hop test, linear sprinting time, stride frequency, stride distance, force-power...
The study followed a cohort design. Sixteen female soccer players competing in the second division of the Spanish league were monitored during the first days of the pre-season. These players were eval...
To examine the selective influences of changes in walking test capability on physical functional performance (COD speed, COD deficit, linear sprint speed, chair stand test, handgrip strength, and unlo...
The performances of eighty women ((age, 64.7 ± 3.38 y; body mass, 66.3 ± 11.15 kg; height, 153.5 ± 5.71 cm, BMI, 28.08 ± 4.00 kg/m...
Strength and conditioning coaches and professionals involved with older women should consider the COD deficit (i.e., linear velocity minus change of direction velocity), as a complementary measure to ...
History of chronic kidney disease and kidney transplantation is known to influence physical performance capacity. The aim of this study was to compare the physical performance of pediatric kidney tran...
Twenty-four pediatric kidney transplant recipients (62.5% boys) were tested at a median age of 10.8 years. Physical performance capacity was tested with a test set including six different components a...
The physical performance capacity in pediatric kidney transplant recipients was lower compared to healthy controls. Surprisingly, no statistically significant correlation was found between graft funct...
The physical performance of pediatric kidney transplant recipients is reduced, especially in those with congenital nephrotic syndrome. Clinical parameters, including graft function, did not predict ph...
The Short Physical Performance Battery (SPPB) is a commonly used tool to assess lower extremity function, composed of three assessments (standing balance, gait speed, and chair stand). While its valid...
In individuals with transtibial amputation, the distal part of the lower extremity is lost. Therefore, the knee joint is of greater importance to be able to provide physical performance. The aim of th...
The study included 21 subjects with transtibial amputation. A digital inclinometer was used to evaluate the joint position sense of the amputated side knee joint. The timed up and go test, the 4-squar...
The mean age of the participants was 52.52 ± 15.68 years. The mean of the error in knee joint position sense was 5.33 degree (standard deviation = 3.08 degree). The error in knee joint position sense ...
The knee joint position sense on the amputated side was found to be associated with physical functional performance in individuals with transtibial amputation. Residual limb knee joint position sense ...
In recent years, there has been a significant increase in the survival rates of cancer patients. However, this has also led to an increase in side effects, such as dyspnoea, which can negatively impac...
Experimental, prospective, longitudinal, randomised study with a parallel fixed-assignment scheme (CG-IG). The patients were selected from the Medical Oncology Service of the University Hospital Compl...
The study sample consisted of 182 patients, with 12 excluded, resulting in a final sample size of n = 170. Sex distribution (CG: 52.9% male and 47.1% female; IG: 49.4% male and 50.6% female). The prim...
The results of this study support the beneficial effects of an exercise re-education programme, carried out by an interdisciplinary team in improving the autonomy of oncology patients with dyspnoea....
The clinical trial was registered in ClinicalTrials.gov (NCT04186754). (03 September 2019)....