questionsmedicales.fr
Acides aminés, peptides et protéines
Protéines
Protéines membranaires
Glycoprotéines membranaires
Syndécanes
Syndécane-3
Syndécane-3 : Questions médicales fréquentes
Termes MeSH sélectionnés :
Postoperative Nausea and Vomiting
Diagnostic
5
Syndécane-3
Tests génétiques
Biopsie
Immunohistochimie
Dosage sanguin
Syndécane-3
Marqueurs tumoraux
Cytokines
Symptômes
5
Dysfonction
Anomalies tissulaires
Cancer
Maladies inflammatoires
Anomalies cutanées
Syndécane-3
Prévention
5
Prévention
Mode de vie sain
Facteurs de risque
Inflammation chronique
Traitements
5
Thérapies ciblées
Anticorps monoclonaux
Effets secondaires
Réactions immunitaires
Traitements expérimentaux
Évaluation
Suivi
Réponse au traitement
Complications
5
Complications
Métastases tumorales
Complications cardiovasculaires
Syndécane-3
Complications neurologiques
Recherche
Gestion
Approche multidisciplinaire
Réversibilité
Traitement approprié
Facteurs de risque
5
Facteurs de risque
Antécédents familiaux
Obésité
Dysfonctionnements
Facteurs environnementaux
Polluants
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"@type": "Question",
"name": "Quels examens sont utilisés pour évaluer le syndécane-3 ?",
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"@type": "Question",
"name": "Le dosage sanguin peut-il aider au diagnostic ?",
"position": 3,
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{
"@type": "Question",
"name": "Quels marqueurs sont associés au syndécane-3 ?",
"position": 4,
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"position": 8,
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"name": "Y a-t-il des symptômes systémiques associés ?",
"position": 9,
"acceptedAnswer": {
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"text": "Des symptômes systémiques comme la fatigue et la douleur peuvent être observés dans certains cas."
}
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"@type": "Question",
"name": "Les symptômes varient-ils d'un patient à l'autre ?",
"position": 10,
"acceptedAnswer": {
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"text": "Oui, les symptômes peuvent varier considérablement selon l'individu et la pathologie associée."
}
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{
"@type": "Question",
"name": "Peut-on prévenir les dysfonctionnements du syndécane-3 ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "La prévention est difficile, mais un mode de vie sain peut réduire certains risques associés."
}
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{
"@type": "Question",
"name": "Y a-t-il des facteurs de risque connus ?",
"position": 12,
"acceptedAnswer": {
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"text": "Oui, des facteurs comme l'inflammation chronique et des prédispositions génétiques sont identifiés."
}
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{
"@type": "Question",
"name": "Des dépistages réguliers sont-ils recommandés ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des dépistages peuvent être recommandés pour les personnes à risque élevé de maladies associées."
}
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{
"@type": "Question",
"name": "L'alimentation influence-t-elle le syndécane-3 ?",
"position": 14,
"acceptedAnswer": {
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"text": "Une alimentation équilibrée peut influencer positivement l'expression du syndécane-3."
}
},
{
"@type": "Question",
"name": "Le stress a-t-il un impact sur le syndécane-3 ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le stress peut affecter l'expression du syndécane-3 et contribuer à des maladies."
}
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{
"@type": "Question",
"name": "Quels traitements ciblent le syndécane-3 ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des thérapies ciblées et des anticorps monoclonaux peuvent être utilisés pour cibler le syndécane-3."
}
},
{
"@type": "Question",
"name": "Le traitement est-il efficace ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'efficacité du traitement dépend de la pathologie et de l'expression du syndécane-3."
}
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{
"@type": "Question",
"name": "Y a-t-il des effets secondaires des traitements ?",
"position": 18,
"acceptedAnswer": {
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"text": "Oui, les traitements peuvent entraîner des effets secondaires comme des réactions immunitaires."
}
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{
"@type": "Question",
"name": "Des traitements expérimentaux existent-ils ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des traitements expérimentaux sont en cours d'évaluation pour cibler le syndécane-3."
}
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{
"@type": "Question",
"name": "Le suivi est-il nécessaire après traitement ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, un suivi régulier est essentiel pour évaluer la réponse au traitement et ajuster si nécessaire."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir avec le syndécane-3 ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des complications comme des métastases tumorales et des troubles immunitaires peuvent survenir."
}
},
{
"@type": "Question",
"name": "Le syndécane-3 est-il lié à des complications cardiovasculaires ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des études suggèrent un lien entre le syndécane-3 et des complications cardiovasculaires."
}
},
{
"@type": "Question",
"name": "Des complications neurologiques sont-elles possibles ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines recherches indiquent que des complications neurologiques peuvent être associées."
}
},
{
"@type": "Question",
"name": "Comment gérer les complications liées au syndécane-3 ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "La gestion des complications nécessite une approche multidisciplinaire et un suivi régulier."
}
},
{
"@type": "Question",
"name": "Les complications sont-elles réversibles ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines complications peuvent être réversibles avec un traitement approprié, d'autres non."
}
},
{
"@type": "Question",
"name": "Quels sont les principaux facteurs de risque ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les facteurs incluent l'âge, les antécédents familiaux et les maladies inflammatoires."
}
},
{
"@type": "Question",
"name": "Le mode de vie influence-t-il les risques ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, un mode de vie sédentaire et une mauvaise alimentation augmentent les risques."
}
},
{
"@type": "Question",
"name": "Les infections jouent-elles un rôle ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines infections chroniques peuvent augmenter le risque de dysfonction du syndécane-3."
}
},
{
"@type": "Question",
"name": "Y a-t-il un lien avec l'obésité ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'obésité est un facteur de risque reconnu pour des dysfonctionnements associés au syndécane-3."
}
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{
"@type": "Question",
"name": "Les facteurs environnementaux sont-ils significatifs ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'exposition à des polluants environnementaux peut influencer l'expression du syndécane-3."
}
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}
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 25/04/2025
Contenu vérifié selon les dernières recommandations médicales
4 publications dans cette catégorie
Affiliations :
Department of Biochemistry, IIB, University of Liverpool, Liverpool, UK.
Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, NY, USA.
Publications dans "Syndécane-3" :
4 publications dans cette catégorie
Affiliations :
Department of Gynecology and Obstetrics, Münster University Hospital, Albert-Schweitzer-Campus 1, D11, 48149 Muenster, Germany.
Publications dans "Syndécane-3" :
4 publications dans cette catégorie
Affiliations :
Department of Pathology and Experimental Cancer Research, Semmelweis University, Budapest, Hungary.
Publications dans "Syndécane-3" :
3 publications dans cette catégorie
Affiliations :
Barts and the London School of Medicine and Dentistry, William Harvey Research Institute, Queen Mary University of London, London, United Kingdom.
Publications dans "Syndécane-3" :
3 publications dans cette catégorie
Affiliations :
Barts and the London School of Medicine and Dentistry, William Harvey Research Institute, Queen Mary University of London, London, United Kingdom.
Publications dans "Syndécane-3" :
3 publications dans cette catégorie
Affiliations :
Pharmacoidea Ltd., H-6726 Szeged, Hungary.
Publications dans "Syndécane-3" :
3 publications dans cette catégorie
Affiliations :
Pharmacoidea Ltd., H-6726 Szeged, Hungary.
Publications dans "Syndécane-3" :
3 publications dans cette catégorie
Affiliations :
Institute for Experimental Medical Research, Oslo University Hospital and University of Oslo, Oslo, Norway.
Publications dans "Syndécane-3" :
3 publications dans cette catégorie
Affiliations :
Institute for Experimental Medical Research, Oslo University Hospital and University of Oslo, Oslo, Norway.
Publications dans "Syndécane-3" :
3 publications dans cette catégorie
Affiliations :
Institute for Experimental Medical Research, Oslo University Hospital and University of Oslo, Oslo, Norway.
K.G. Jebsen Center for Cardiac Research, University of Oslo, Oslo, Norway.
Publications dans "Syndécane-3" :
3 publications dans cette catégorie
Affiliations :
ICBMS, UMR 5246 CNRS - University Lyon 1, Univ Lyon, Villeurbanne, France.
Publications dans "Syndécane-3" :
3 publications dans cette catégorie
Affiliations :
Biotech Research & Innovation Centre, University of Copenhagen, 2200 Copenhagen, Denmark.
Publications dans "Syndécane-3" :
3 publications dans cette catégorie
Affiliations :
Department of Gynecology and Obstetrics, Münster University Hospital, Munster, Germany.
Disciplina de Biologia Molecular, Departamento de Bioquímica, Universidade Federal de São Paulo, Sao Paulo, Brazil.
Publications dans "Syndécane-3" :
3 publications dans cette catégorie
Affiliations :
Disciplina de Biologia Molecular, Departamento de Bioquímica, Universidade Federal de São Paulo, Sao Paulo, Brazil.
Departamento de Ciências Biológicas, Instituto de Ciências Ambientais, Químicas e Farmacêuticas, Universidade Federal de São Paulo, Sao Paulo, Brazil.
Publications dans "Syndécane-3" :
2 publications dans cette catégorie
Affiliations :
Barts and the London School of Medicine and Dentistry, William Harvey Research Institute, Queen Mary University of London, London, United Kingdom.
Publications dans "Syndécane-3" :
2 publications dans cette catégorie
Affiliations :
Albert Szent-Györgyi Clinical Center, Department of Medicine, Faculty of Medicine, University of Szeged, H-6720 Szeged, Hungary.
Publications dans "Syndécane-3" :
2 publications dans cette catégorie
Affiliations :
Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, NY, USA.
Publications dans "Syndécane-3" :
2 publications dans cette catégorie
Affiliations :
Institute for Experimental Medical Research, Oslo University Hospital and University of Oslo, Oslo, Norway.
Bjørknes College, Oslo, Norway.
Publications dans "Syndécane-3" :
2 publications dans cette catégorie
Affiliations :
Institute for Experimental Medical Research, Oslo University Hospital and University of Oslo, Oslo, Norway.
K.G. Jebsen Center for Cardiac Research, University of Oslo, Oslo, Norway.
Publications dans "Syndécane-3" :
2 publications dans cette catégorie
Affiliations :
ICBMS, UMR 5246 CNRS - University Lyon 1, Univ Lyon, Villeurbanne, France.
Publications dans "Syndécane-3" :
Postoperative nausea and vomiting (PONV) prophylaxis is consistently considered a key indicator of anesthesia care quality. PONV may disproportionately impact disadvantaged patients. The primary objec...
We conducted a retrospective analysis of all patients eligible for an institution-specific PONV prophylaxis protocol (2015-2017). Sociodemographic and PONV risk data were collected. Primary outcomes w...
Within the 8384 patient sample, Black patients had a 17% lower risk of PONV than White patients (adjusted odds ratio [aOR], 0.83; 95% confidence interval [CI], 0.73-0.95; P = .006). When there was adh...
Racial and sociodemographic disparities exist in the incidence of PONV and clinician adherence to a PONV prophylaxis protocol. Awareness of such disparities in PONV prophylaxis could improve the quali...
This study was conducted to assess the cost-effectiveness of prophylactic use of ramosetron compared to no antiemetic medications for the prevention of postoperative nausea and vomiting (PONV) from th...
A decision analytic model was constructed to assess the cost-effectiveness of prophylactic ramosetron use versus no antiemetic therapy at 24-hour and 48-hour periods post-surgery over a 5-day duration...
The base-case analysis showed that, on average, patients treated with prophylactic ramosetron had lower costs from both the healthcare payer (US$16.88 vs US$17.33) and societal (US$16.89 vs US$18.72) ...
The results demonstrated that prophylactic use of ramosetron compared to no antiemetic therapy is highly cost-effective to prevent PONV for patients undergoing surgery from both healthcare payer and s...
Despite the availability of several classes of antiemetics, postoperative nausea and vomiting (PONV) remains a substantial burden for patients following surgery, resulting in patient dissatisfaction a...
Postoperative/postdischarge nausea and vomiting (PONV/PDNV) remain relevant issues in perioperative care. Especially in ambulatory surgery, PONV can prevent discharge or lead to unplanned readmission....
The evidence for the management of PONV is now quite good but is still inadequately implemented. A universal, multimodal rather than risk-adapted approach for PONV prophylaxis is now recommended. The ...
PDNV management is based primarily on consequent prophylaxis and therapy of PONV....
Postoperative/postdischarge nausea and vomiting (PONV/PDNV) remains a relevant issue in perioperative care. Especially in outpatient surgery, PONV can prevent discharge or lead to unplanned readmissio...
Evidence on prophylaxis and treatment of PONV is growing, but implementation remains poor....
A liberal, universal PONV management is now endorsed by the guidelines. Specific evidence concerning prevention and (at-home) treatment of PDNV is still scarce....
To examine the risks of postoperative nausea and vomiting (PONV) in breast cancer patients....
Descriptive, cross-sectional study....
The study was conducted in the surgical oncology department of a tertiary hospital between June 2020 and December 2020. A total of 83 female patients who were scheduled for surgical treatment for brea...
A significant relationship was found between age and PONV at the 2nd, 4th, 8th, 24th and 48th hours after surgery (respectively: P = .00, P = .00, P = .00, P = .00, P = .00). There was a significant c...
While women with breast cancer who have undergone mastectomy have the highest risk of postoperative and nausea vomiting in terms of age and pain severity, the duration of the operation and the first o...
Genetic variants may affect drug efficacy on postoperative nausea and vomiting (PONV). The understanding of these mechanisms will help to identify the surgical patients who might benefit from specific...
We included articles published from 2005 to 2022, utilizing the electronic databases PUBMED, EMBASE, COHRANE Library and ScienceDirect. To explore the relationship between genetic variations and 5HT3 ...
Our search retrieved a total of 70 articles; 29 of them were included in the present review. Regarding polymorphisms of the CYP2D6 gene and the efficacy of serotonin antagonists in PONV, the ultra-rap...
This review highlights that inefficacy of a specific drug in managing PONV could be attributed to specific genetic profiles and patients would possibly benefit from a drug switch....
Intraoperative use of glucocorticoids is effective for postoperative nausea and vomiting prophylaxis and can also provide early postoperative analgesic effects, but the consequences for chronic post-s...
The incidence of postoperative nausea and vomiting (PONV) after microvascular decompression (MVD) surgery is high; however, its underlying mechanisms remain unknown. Serum 5-hydroxytryptamine (5-HT) l...
This prospective study included 85 patients with hemifacial spasm who received MVD surgery. Blood samples were collected preoperatively, postoperatively, and on postoperative day 1, and cerebrospinal ...
In the multivariate regression analysis, PONV within 24 h after MVD surgery was associated with elevated cerebrospinal fluid 5-HT levels [odds ratio (OR) = 1.21, 95% confidence interval (CI): 1.01-1.4...
Our study found that the cerebrospinal fluid 5-HT levels is an independent risk factor for PONV within 24 h after MVD surgery....
This study is designed to identify risk factors of postoperative nausea and vomiting (PONV) in patients after gynecologic laparoscopic surgery and establish a nomogram model....
In this retrospective and multicenter study, we collected and analyzed data from 1233 patients who underwent gynecologic laparoscopic surgery. The Lasso algorithm was used to optimize the selection of...
The dosage of sufentanil in patient-controlled intravenous analgesia (PCIA), the dosage of remifentanil, the use of neostigmine, duration of surgery and the maximum value of the P...
A nomogram model was developed to predict the incidence of PONV in patients after gynecologic laparoscopic surgery. This model was found to be reliable and of high clinical value....