questionsmedicales.fr
Acides aminés, peptides et protéines
Protéines
Protéines membranaires
Glycoprotéines membranaires
Syndécanes
Syndécane-3
Syndécane-3 : Questions médicales fréquentes
Termes MeSH sélectionnés :
Diagnostic
5
Syndécane-3
Tests génétiques
Biopsie
Immunohistochimie
Dosage sanguin
Syndécane-3
Marqueurs tumoraux
Cytokines
Symptômes
5
Dysfonction
Anomalies tissulaires
Cancer
Maladies inflammatoires
Anomalies cutanées
Syndécane-3
Prévention
5
Prévention
Mode de vie sain
Facteurs de risque
Inflammation chronique
Traitements
5
Thérapies ciblées
Anticorps monoclonaux
Effets secondaires
Réactions immunitaires
Traitements expérimentaux
Évaluation
Suivi
Réponse au traitement
Complications
5
Complications
Métastases tumorales
Complications cardiovasculaires
Syndécane-3
Complications neurologiques
Recherche
Gestion
Approche multidisciplinaire
Réversibilité
Traitement approprié
Facteurs de risque
5
Facteurs de risque
Antécédents familiaux
Obésité
Dysfonctionnements
Facteurs environnementaux
Polluants
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"@type": "Question",
"name": "Comment diagnostiquer une anomalie du syndécane-3 ?",
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"text": "Le diagnostic repose sur des tests génétiques et des analyses de tissus pour évaluer l'expression du syndécane-3."
}
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{
"@type": "Question",
"name": "Quels examens sont utilisés pour évaluer le syndécane-3 ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des biopsies et des analyses immunohistochimiques peuvent être réalisées pour évaluer le syndécane-3."
}
},
{
"@type": "Question",
"name": "Le dosage sanguin peut-il aider au diagnostic ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "Actuellement, il n'existe pas de dosage sanguin standardisé pour le syndécane-3."
}
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{
"@type": "Question",
"name": "Quels marqueurs sont associés au syndécane-3 ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des marqueurs tumoraux et des cytokines peuvent être associés à l'expression du syndécane-3."
}
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{
"@type": "Question",
"name": "Le diagnostic est-il difficile à établir ?",
"position": 5,
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{
"@type": "Question",
"name": "Quels symptômes sont liés à une dysfonction du syndécane-3 ?",
"position": 6,
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"@type": "Question",
"name": "Le syndécane-3 est-il lié à des maladies spécifiques ?",
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}
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"@type": "Question",
"name": "Peut-on observer des symptômes cutanés ?",
"position": 8,
"acceptedAnswer": {
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"text": "Des anomalies cutanées peuvent survenir en raison de l'implication du syndécane-3 dans la peau."
}
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{
"@type": "Question",
"name": "Y a-t-il des symptômes systémiques associés ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des symptômes systémiques comme la fatigue et la douleur peuvent être observés dans certains cas."
}
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{
"@type": "Question",
"name": "Les symptômes varient-ils d'un patient à l'autre ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les symptômes peuvent varier considérablement selon l'individu et la pathologie associée."
}
},
{
"@type": "Question",
"name": "Peut-on prévenir les dysfonctionnements du syndécane-3 ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "La prévention est difficile, mais un mode de vie sain peut réduire certains risques associés."
}
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{
"@type": "Question",
"name": "Y a-t-il des facteurs de risque connus ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des facteurs comme l'inflammation chronique et des prédispositions génétiques sont identifiés."
}
},
{
"@type": "Question",
"name": "Des dépistages réguliers sont-ils recommandés ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des dépistages peuvent être recommandés pour les personnes à risque élevé de maladies associées."
}
},
{
"@type": "Question",
"name": "L'alimentation influence-t-elle le syndécane-3 ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une alimentation équilibrée peut influencer positivement l'expression du syndécane-3."
}
},
{
"@type": "Question",
"name": "Le stress a-t-il un impact sur le syndécane-3 ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le stress peut affecter l'expression du syndécane-3 et contribuer à des maladies."
}
},
{
"@type": "Question",
"name": "Quels traitements ciblent le syndécane-3 ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des thérapies ciblées et des anticorps monoclonaux peuvent être utilisés pour cibler le syndécane-3."
}
},
{
"@type": "Question",
"name": "Le traitement est-il efficace ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'efficacité du traitement dépend de la pathologie et de l'expression du syndécane-3."
}
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{
"@type": "Question",
"name": "Y a-t-il des effets secondaires des traitements ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les traitements peuvent entraîner des effets secondaires comme des réactions immunitaires."
}
},
{
"@type": "Question",
"name": "Des traitements expérimentaux existent-ils ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des traitements expérimentaux sont en cours d'évaluation pour cibler le syndécane-3."
}
},
{
"@type": "Question",
"name": "Le suivi est-il nécessaire après traitement ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, un suivi régulier est essentiel pour évaluer la réponse au traitement et ajuster si nécessaire."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir avec le syndécane-3 ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des complications comme des métastases tumorales et des troubles immunitaires peuvent survenir."
}
},
{
"@type": "Question",
"name": "Le syndécane-3 est-il lié à des complications cardiovasculaires ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des études suggèrent un lien entre le syndécane-3 et des complications cardiovasculaires."
}
},
{
"@type": "Question",
"name": "Des complications neurologiques sont-elles possibles ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines recherches indiquent que des complications neurologiques peuvent être associées."
}
},
{
"@type": "Question",
"name": "Comment gérer les complications liées au syndécane-3 ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "La gestion des complications nécessite une approche multidisciplinaire et un suivi régulier."
}
},
{
"@type": "Question",
"name": "Les complications sont-elles réversibles ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines complications peuvent être réversibles avec un traitement approprié, d'autres non."
}
},
{
"@type": "Question",
"name": "Quels sont les principaux facteurs de risque ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les facteurs incluent l'âge, les antécédents familiaux et les maladies inflammatoires."
}
},
{
"@type": "Question",
"name": "Le mode de vie influence-t-il les risques ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, un mode de vie sédentaire et une mauvaise alimentation augmentent les risques."
}
},
{
"@type": "Question",
"name": "Les infections jouent-elles un rôle ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines infections chroniques peuvent augmenter le risque de dysfonction du syndécane-3."
}
},
{
"@type": "Question",
"name": "Y a-t-il un lien avec l'obésité ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'obésité est un facteur de risque reconnu pour des dysfonctionnements associés au syndécane-3."
}
},
{
"@type": "Question",
"name": "Les facteurs environnementaux sont-ils significatifs ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'exposition à des polluants environnementaux peut influencer l'expression du syndécane-3."
}
}
]
}
]
}
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 25/04/2025
Contenu vérifié selon les dernières recommandations médicales
4 publications dans cette catégorie
Affiliations :
Department of Biochemistry, IIB, University of Liverpool, Liverpool, UK.
Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, NY, USA.
Publications dans "Syndécane-3" :
4 publications dans cette catégorie
Affiliations :
Department of Gynecology and Obstetrics, Münster University Hospital, Albert-Schweitzer-Campus 1, D11, 48149 Muenster, Germany.
Publications dans "Syndécane-3" :
4 publications dans cette catégorie
Affiliations :
Department of Pathology and Experimental Cancer Research, Semmelweis University, Budapest, Hungary.
Publications dans "Syndécane-3" :
3 publications dans cette catégorie
Affiliations :
Barts and the London School of Medicine and Dentistry, William Harvey Research Institute, Queen Mary University of London, London, United Kingdom.
Publications dans "Syndécane-3" :
3 publications dans cette catégorie
Affiliations :
Barts and the London School of Medicine and Dentistry, William Harvey Research Institute, Queen Mary University of London, London, United Kingdom.
Publications dans "Syndécane-3" :
3 publications dans cette catégorie
Affiliations :
Pharmacoidea Ltd., H-6726 Szeged, Hungary.
Publications dans "Syndécane-3" :
3 publications dans cette catégorie
Affiliations :
Pharmacoidea Ltd., H-6726 Szeged, Hungary.
Publications dans "Syndécane-3" :
3 publications dans cette catégorie
Affiliations :
Institute for Experimental Medical Research, Oslo University Hospital and University of Oslo, Oslo, Norway.
Publications dans "Syndécane-3" :
3 publications dans cette catégorie
Affiliations :
Institute for Experimental Medical Research, Oslo University Hospital and University of Oslo, Oslo, Norway.
Publications dans "Syndécane-3" :
3 publications dans cette catégorie
Affiliations :
Institute for Experimental Medical Research, Oslo University Hospital and University of Oslo, Oslo, Norway.
K.G. Jebsen Center for Cardiac Research, University of Oslo, Oslo, Norway.
Publications dans "Syndécane-3" :
3 publications dans cette catégorie
Affiliations :
ICBMS, UMR 5246 CNRS - University Lyon 1, Univ Lyon, Villeurbanne, France.
Publications dans "Syndécane-3" :
3 publications dans cette catégorie
Affiliations :
Biotech Research & Innovation Centre, University of Copenhagen, 2200 Copenhagen, Denmark.
Publications dans "Syndécane-3" :
3 publications dans cette catégorie
Affiliations :
Department of Gynecology and Obstetrics, Münster University Hospital, Munster, Germany.
Disciplina de Biologia Molecular, Departamento de Bioquímica, Universidade Federal de São Paulo, Sao Paulo, Brazil.
Publications dans "Syndécane-3" :
3 publications dans cette catégorie
Affiliations :
Disciplina de Biologia Molecular, Departamento de Bioquímica, Universidade Federal de São Paulo, Sao Paulo, Brazil.
Departamento de Ciências Biológicas, Instituto de Ciências Ambientais, Químicas e Farmacêuticas, Universidade Federal de São Paulo, Sao Paulo, Brazil.
Publications dans "Syndécane-3" :
2 publications dans cette catégorie
Affiliations :
Barts and the London School of Medicine and Dentistry, William Harvey Research Institute, Queen Mary University of London, London, United Kingdom.
Publications dans "Syndécane-3" :
2 publications dans cette catégorie
Affiliations :
Albert Szent-Györgyi Clinical Center, Department of Medicine, Faculty of Medicine, University of Szeged, H-6720 Szeged, Hungary.
Publications dans "Syndécane-3" :
2 publications dans cette catégorie
Affiliations :
Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, NY, USA.
Publications dans "Syndécane-3" :
2 publications dans cette catégorie
Affiliations :
Institute for Experimental Medical Research, Oslo University Hospital and University of Oslo, Oslo, Norway.
Bjørknes College, Oslo, Norway.
Publications dans "Syndécane-3" :
2 publications dans cette catégorie
Affiliations :
Institute for Experimental Medical Research, Oslo University Hospital and University of Oslo, Oslo, Norway.
K.G. Jebsen Center for Cardiac Research, University of Oslo, Oslo, Norway.
Publications dans "Syndécane-3" :
2 publications dans cette catégorie
Affiliations :
ICBMS, UMR 5246 CNRS - University Lyon 1, Univ Lyon, Villeurbanne, France.
Publications dans "Syndécane-3" :
Anterior vitrectomy is a skill all cataract surgeons should develop and master. Every surgeon will have complications at some point in his/her career. Complication management should be part of the sur...
This video will serve as a step-by-step practical guide to the intraoperative management of posterior capsular rent by simplifying the anterior vitrectomy procedure....
This video will demonstrate how to tackle the dreaded complication of a posterior capsular rent with vitreous disturbance, and achieve optimal postoperative outcomes....
We demonstrate how a PCR appears, and once identified, how to proceed. In addition, nuances regarding foot positions and different vitrectomy modes are included. Biaxial vitrectomy is explained. Lens ...
https://youtu.be/dTo7sMpe8h8....
Recurrent retinal detachment (Re-RD) usually affects the prognosis of surgery for rhegmatogenous retinal detachment (RRD). Previous clinical studies of Re-RD were not specific. This study aimed to ana...
This is a retrospective case series analyzed the ocular characteristics of 20 recurrent and contralateral eyes, evaluated the significance of the associations between variables before reoperation and ...
Patients with phakic eyes, those undergoing only one surgery, and those with more than one break had better final BCVA. The final BCVA was negatively correlated with the axial length and positively co...
Revitrectomy without retinectomy or scleral buckling can effectively treat Re-RD in post-vitrectomy eyes. In Re-RD patients with no definite retinal break detected preoperatively, the retinal hole usu...
To compare outcomes of acute endophthalmitis (EO) managed with either primary vitrectomy (PV) or primary intravitreal antibiotics (vancomycin and ceftazidime) followed by early vitrectomy (PIAEV) comb...
This was a prospective, comparative observational study of acute EO cases admitted to a regional vitreoretinal service over 18 months. Depending on whether immediate vitrectomy (within 6 h) was achiev...
The study included 41 EO cases. There were 19 post-injection EO, 18 post-cataract EO, three post-vitrectomy EO, and one blebitis-related EO. Fifteen of 19 PV cases and 15 of 21 PIAEV had a clinically ...
Primary vitrectomy or PIAEV allowed for vitrectomy for all cases of acute EO in a large region. Most eyes in both groups achieved a clinically meaningful improvement in BCVA. By combining culture with...
Pars plana vitrectomy (PPV) is the main treatment modality for patients with severe diabetic retinopathy. With the development of systems for microincision, wide-angle viewing, digitally assisted visu...
Endophthalmitis is a sight-threatening emergency that requires prompt diagnosis and treatment. The condition is characterised by purulent inflammation of the intraocular fluids caused by an infective ...
To assess the potential role of combined pars plana vitrectomy and intravitreal antibiotics in the acute management of exogenous endophthalmitis, versus the standard of care, defined as vitreous tap a...
We searched the Cochrane Central Register of Controlled Trials (CENTRAL; which contains the Cochrane Eyes and Vision Trials Register; 2022, Issue 5); Ovid MEDLINE; Ovid Embase; the International Stand...
We included randomised controlled trials (RCTs) that compared pars plana vitrectomy and intravitreal injection of antibiotics versus intravitreal injection of antibiotics alone, for the immediate mana...
We used standard methods expected by Cochrane. Two review authors independently screened search results and extracted data. We considered the following outcomes: visual acuity improvement and change i...
To assess the efficacy and safety of topical insulin (TI) for treating neurotrophic keratopathy (NK) within one-month post-diabetic vitrectomy (DV) compared to conventional non-invasive measures, we c...
Ophthalmologists have used hyaluronan (HA) products as adjuncts to ocular surgery since the 1970s. However, HA products are not always functional in surgeries of the posterior eye segment due to their...
The accurate encoding of operation notes is essential for activity-based funding and workforce planning. The aim of this project was to evaluate the procedural coding accuracy of vitrectomy and to dev...
This retrospective cohort study involved vitrectomy operation notes between a 21-month period at the Royal Adelaide Hospital. Coding of procedures were based on the Medicare Benefits Schedule (MBS)-th...
There were a total of 1724 procedures with individual codes performed within 617 vitrectomy operation notes totalling $1 528 086.60 after manual review. A total of 1147 (66.5%) codes were missed in th...
Machine learning has been successful in the classification of vitrectomy operation note encoding. We recommend a combined human and machine learning approach to clinical coding as automation may facil...
To compare the visual, refractive, and anatomical outcomes and incidence of complications between combined pars plana vitrectomy and phacoemulsification (phacovitrectomy) versus pars plana vitrectomy ...
Two independent reviewers searched MEDLINE, Cochrane Central, and Web of Science to identify relevant articles. Prospective or retrospective studies comparing PPV-only and phacovitrectomy for RRD were...
Seven studies (788 eyes) were selected, including two clinical trials and five retrospective comparative case series. The single surgery success rate was similar in PPV-only and phacovitrectomy groups...
There was no significant difference between the two groups regarding the anatomical outcome. Slightly better visual and refractive results were observed in the PPV-only group. However, the results sho...
Macular hole (MH) is a full-thickness defect in the central portion of the retina that causes loss of central vision. According to the usual definition, a large MH has a diameter greater than 400 µm a...
To evaluate the clinical effectiveness and safety of pars plana vitrectomy with the inverted internal limiting membrane flap technique versus pars plana vitrectomy with conventional internal limiting ...
The Cochrane Eyes and Vision Information Specialist searched CENTRAL, MEDLINE, Embase, two other databases, and two trials registries on 12 December 2022....
We included randomized controlled trials (RCTs) that evaluated PPV with ILM peeling versus PPV with inverted ILM flap for treatment of large MHs (with a basal diameter greater than 400 µm at the narro...
We used standard methodological procedures expected by Cochrane and assessed the certainty of the body of evidence using GRADE....
We included four RCTs (285 eyes of 275 participants; range per study 24 to 91 eyes). Most participants were women (63%), and of older age (range of means 59.4 to 66 years). Three RCTs were single-cent...
We found low-certainty evidence from four small RCTs that PPV with the inverted ILM flap technique is superior to PPV with ILM peeling with respect to BCVA gains at three or more months after surgery....