Oui, des études suggèrent un lien entre TGF-bêta et certains types de cancer.
CancerTGF-bêta
#4
Les troubles neurologiques peuvent-ils être liés ?
Oui, des troubles neurologiques peuvent être associés à des déséquilibres du TGF-bêta.
Troubles neurologiquesDéséquilibres
#5
Comment gérer les complications ?
La gestion des complications nécessite une approche multidisciplinaire et un suivi régulier.
Gestion des complicationsSuivi régulier
Facteurs de risque
5
#1
Quels sont les principaux facteurs de risque ?
Les facteurs incluent des antécédents familiaux, des maladies auto-immunes et l'exposition à des toxines.
Antécédents familiauxMaladies auto-immunes
#2
Le vieillissement est-il un facteur de risque ?
Oui, le vieillissement peut augmenter le risque de dysfonction des protéines de liaison au TGF-bêta.
VieillissementDysfonction
#3
L'obésité influence-t-elle le risque ?
Oui, l'obésité est associée à une inflammation chronique, augmentant le risque de troubles.
ObésitéInflammation chronique
#4
Le stress a-t-il un impact ?
Oui, le stress chronique peut exacerber les troubles liés au TGF-bêta.
StressTroubles
#5
Les infections peuvent-elles être un facteur ?
Oui, certaines infections peuvent déclencher des réponses inflammatoires affectant le TGF-bêta.
InfectionsRéponses inflammatoires
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"text": "Le diagnostic repose sur des tests sanguins et des analyses génétiques pour détecter des mutations."
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"position": 9,
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"name": "Y a-t-il des signes d'inflammation systémique ?",
"position": 10,
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"text": "Oui, des signes comme la fièvre et la fatigue peuvent indiquer une inflammation systémique."
}
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"@type": "Question",
"name": "Comment prévenir les troubles liés au TGF-bêta ?",
"position": 11,
"acceptedAnswer": {
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"text": "La prévention passe par un mode de vie sain et la gestion des maladies inflammatoires."
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"@type": "Question",
"name": "Y a-t-il des mesures spécifiques à prendre ?",
"position": 12,
"acceptedAnswer": {
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"text": "Éviter le tabac et l'alcool peut réduire le risque de complications liées au TGF-bêta."
}
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"@type": "Question",
"name": "Les vaccinations sont-elles importantes ?",
"position": 13,
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"name": "Quels traitements sont disponibles pour les troubles liés au TGF-bêta ?",
"position": 16,
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"@type": "Question",
"name": "La thérapie génique est-elle une option ?",
"position": 17,
"acceptedAnswer": {
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"name": "Les corticostéroïdes sont-ils utilisés ?",
"position": 18,
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"name": "Y a-t-il des traitements expérimentaux ?",
"position": 19,
"acceptedAnswer": {
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"text": "Des traitements expérimentaux, comme les inhibiteurs de TGF-bêta, sont en cours d'évaluation."
}
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"@type": "Question",
"name": "Les changements de mode de vie peuvent-ils aider ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des changements comme une alimentation saine et l'exercice peuvent améliorer les symptômes."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les complications incluent des fibroses, des troubles respiratoires et des maladies auto-immunes."
}
},
{
"@type": "Question",
"name": "Les complications cardiovasculaires sont-elles possibles ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des complications cardiovasculaires peuvent survenir en raison d'une inflammation chronique."
}
},
{
"@type": "Question",
"name": "Y a-t-il un risque accru de cancer ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des études suggèrent un lien entre TGF-bêta et certains types de cancer."
}
},
{
"@type": "Question",
"name": "Les troubles neurologiques peuvent-ils être liés ?",
"position": 24,
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}
},
{
"@type": "Question",
"name": "Comment gérer les complications ?",
"position": 25,
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"@type": "Answer",
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}
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"name": "Quels sont les principaux facteurs de risque ?",
"position": 26,
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"text": "Les facteurs incluent des antécédents familiaux, des maladies auto-immunes et l'exposition à des toxines."
}
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{
"@type": "Question",
"name": "Le vieillissement est-il un facteur de risque ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le vieillissement peut augmenter le risque de dysfonction des protéines de liaison au TGF-bêta."
}
},
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"@type": "Question",
"name": "L'obésité influence-t-elle le risque ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'obésité est associée à une inflammation chronique, augmentant le risque de troubles."
}
},
{
"@type": "Question",
"name": "Le stress a-t-il un impact ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le stress chronique peut exacerber les troubles liés au TGF-bêta."
}
},
{
"@type": "Question",
"name": "Les infections peuvent-elles être un facteur ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certaines infections peuvent déclencher des réponses inflammatoires affectant le TGF-bêta."
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Department of Medicine and Therapeutics, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong 999077, China.
Guangdong Academy of Sciences, Guangdong Provincial People's Hospital Joint Research Laboratory on Immunological and Genetic Kidney Diseases, The Chinese University of Hong Kong, Hong Kong 999077, China.
Publications dans "Protéines de liaison au TGF-bêta latent" :
TGF-β and Cancer Group, Oncobell Program, Bellvitge Biomedical Research Institute, (IDIBELL) and University of Barcelona, L'Hospitalet de Llobregat, 08007 Barcelona, Spain.
Oncology Program, CIBEREHD, National Biomedical Research Institute on Liver and Gastrointestinal Diseases, Instituto de Salud Carlos III, 08907 Madrid, Spain.
Publications dans "Protéines de liaison au TGF-bêta latent" :
Istinye University Faculty of Medicine, Department of Internal Medicine and Rheumatology, WASOG Sarcoidosis Clinic, Turkey. Electronic address: senolkobak@yahoo.com.
Publications dans "Protéines de liaison au TGF-bêta latent" :
Balancing the economic costs related to mental illness is a pressing matter globally. Scarce monetary and staff resources impose an ongoing challenge. Therapeutic leaves (TL) are an established clinic...
We analyzed the association between the number of TL and direct inpatient healthcare costs in a sample of 3151 inpatients, using a tweedie multiple regression model, including eleven confounders. Usin...
The tweedie model showed that the number of TL was associated with lower costs following the initial inpatient stay (B = -.141, CI 95% = [-0.225, -.057], p < 0.001). Results of the multiple linear and...
Our findings suggest a link between TL and direct inpatient healthcare costs. TL might lower direct inpatient healthcare costs. In the future RCTs might examine whether an increased utilization of TL ...
Loneliness among the elderly is a widespread phenomenon and is connected to various negative health outcomes. Nevertheless, loneliness among elderly inpatients, especially those with a psychiatric dia...
N = 100 elderly inpatients of a somatic and psychiatric ward were included. Levels of loneliness were assessed, as were potential predictors such as depression, psychological resilience, severity of m...
37% of all inpatients reported elevated levels of loneliness. Significant predictor variables were self-reported depressive symptoms, well-being, severity of mental illness, being single and living wi...
Elderly inpatients experience high levels of loneliness, especially those with a mental disorder. Interventions to reduce loneliness in this population should address predictors of loneliness, prefera...
Hirschsprung disease (HD) is associated with significant morbidities including long-term bowel dysfunction. The aim of this study was to update national and regional trends in the inpatient care utili...
We identified all pediatric admissions with a diagnosis of HD within the NIS from 2009 through 2014. We analyzed HD discharges with respect to various demographic and clinical factors, specifically tr...
National estimates of HD-discharges showed no significant trend between 2009 and 2014 ( P = 0.27), with estimated relative incidence ranging from 46 to 70 per 100,000 pediatric discharges. Inflation-a...
Increasing cost of HD-related hospitalization despite decreasing LOS was observed in this cohort. Stable rate of hospitalizations with increasing proportions of pull-through procedures among neonates ...
Inpatient falls have a significant impact on the outcomes of older patients during inpatient rehabilitation. A retrospective case-control study was conducted using data of 7066 adults aged 55 yrs or o...
Symptoms of burnout are highly prevalent among physiatrists, and prior studies have helped identify key contributors to this epidemic of burnout. Little is known about the physician stressors unique t...
To identify what IRF leaders perceive as stress points contributing to burnout among inpatient rehabilitation physicians and what, if any, interventions their programs have implemented to help mitigat...
10 item cross-sectional survey study of IRF physician and nonphysician leaders in the United States....
104 physicians serving in the roles of IRF medical director, director of rehabilitation, and/or executive leadership and 19 nonphysician IRF leaders....
Regulatory demands, late admissions, understaffing, and on-call responsibilities were the major stress points most identified as contributing to physician burnout among both the physician and nonphysi...
There are stressors unique to the practice of inpatient rehabilitation that are likely contributing to physiatrist burnout, including late admissions and on-call responsibilities. Many IRFs have begun...
The complexity of antiparkinsonian medications makes patients vulnerable to medication deviations. This study examines the frequency and outcomes of deviations between outpatient and inpatient medicat...
We included hospital admissions of patients with PD during a 12-month period at the Cleveland Clinic Main and Fairview campuses. Outpatient regimens were compared with hospital medication administrati...
The study included 492 patients with 725 admissions. Of those on time-critical medications, 43% had a LEDD deviation and 19% had levodopa formulation substitutions. Of the admission days with known ou...
Deviations between outpatient and hospital regimens, and administration of antidopaminergic medications, were associated with poor outcomes....
Merkel Cell Carcinoma is a rare and aggressive cutaneous carcinoma with a propensity for metastasis and death. Our study describes the prevalence, sociodemographics and inpatient mortality of Merkel C...
To construct a venous thromboembolism (VTE) risk assessment model specifically for inpatients with cancer....
Patients were included according to the inclusion criteria. Univariate and multivariate analyses of all variables were included to develop a VTE risk assessment model applicable to the derivation coho...
A total of 944 cancer patients were included in this study. Alfalfa-inpatient-CAT model, a risk assessment model for VTE in hospitalized cancer patients, was established, which mainly includes hyperte...
This study developed a new VTE risk assessment model - Alfalfa-inpatient-CAT model - for hospitalized cancer patients at high risk of thrombosis. This model has a good fitting degree and discriminant ...
Electroconvulsive therapy (ECT) is an essential procedure for a range of psychiatric conditions. Multiple single-center studies have documented reduction in ECT administration in 2020 because of the c...
The 2019 and 2020 National Inpatient Sample, an administrative database of inpatient hospitalizations in the United States, was queried for hospitalizations involving the delivery of ECT based on proc...
In the 2019 NIS, 14,230 inpatient hospitalizations (95% confidence interval, 12,936-15,524) involved the use of ECT, with a cumulative 52,450 inpatient ECT procedures administered. In 2020, the number...
Electroconvulsive therapy use among general hospital inpatients declined between 2019 and 2020, with regional variability in the magnitude of change. Further study is warranted into the root causes an...
Inpatient rehabilitation plays an important role in treating neurological diseases in children and adolescents. However, there is a lack of current research concerning this matter. This retrospective ...
We reviewed medical records of patients, diagnosed with cerebral palsy, traumatic brain injury (TBI), or stroke who had an inpatient rehabilitation at the Department of Neuropediatrics of St. Mauritiu...
A total of 738 patients with a mean age of 9.2 (± 5.1) years and a mean LOS of 53.8 (± 33.7) days were included; 38.5% were female. Patients, regardless of their diagnosis, sex, or age, demonstrated h...
This is a current study, supporting the effectiveness of neuropediatric inpatient rehabilitation and affirming its value in treating neurological diseases in children and adolescents....
