Titre : Antigène HLA-B37

Antigène HLA-B37 : Questions médicales fréquentes

Termes MeSH sélectionnés :

Graft Rejection
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?\nHLA-B37 est-il lié à des symptômes allergiques ?", "url": "https://questionsmedicales.fr/mesh/D059912?mesh_terms=Graft+Rejection&page=2#section-symptômes" }, { "@type": "MedicalWebPage", "name": "Prévention", "headline": "Prévention sur Antigène HLA-B37", "description": "Peut-on prévenir les maladies liées à HLA-B37 ?\nY a-t-il des mesures préventives spécifiques ?\nLes tests génétiques aident-ils à la prévention ?\nLes vaccinations sont-elles utiles ?\nLe stress influence-t-il les maladies liées à HLA-B37 ?", "url": "https://questionsmedicales.fr/mesh/D059912?mesh_terms=Graft+Rejection&page=2#section-prévention" }, { "@type": "MedicalWebPage", "name": "Traitements", "headline": "Traitements sur Antigène HLA-B37", "description": "Quels traitements sont disponibles pour les maladies liées à HLA-B37 ?\nLe traitement dépend-il du type de maladie ?\nLes greffes sont-elles affectées par HLA-B37 ?\nY a-t-il des traitements préventifs pour HLA-B37 ?\nLes traitements sont-ils efficaces ?", "url": "https://questionsmedicales.fr/mesh/D059912?mesh_terms=Graft+Rejection&page=2#section-traitements" }, { "@type": "MedicalWebPage", "name": "Complications", "headline": "Complications sur Antigène HLA-B37", "description": "Quelles complications peuvent survenir avec HLA-B37 ?\nHLA-B37 augmente-t-il le risque de cancer ?\nLes complications sont-elles réversibles ?\nComment prévenir les complications liées à HLA-B37 ?\nLes complications varient-elles selon les individus ?", "url": "https://questionsmedicales.fr/mesh/D059912?mesh_terms=Graft+Rejection&page=2#section-complications" }, { "@type": "MedicalWebPage", "name": "Facteurs de risque", "headline": "Facteurs de risque sur Antigène HLA-B37", "description": "Quels sont les facteurs de risque pour HLA-B37 ?\nL'âge influence-t-il le risque lié à HLA-B37 ?\nLe sexe joue-t-il un rôle dans le risque ?\nLes infections augmentent-elles le risque ?\nLe mode de vie influence-t-il le risque ?", "url": "https://questionsmedicales.fr/mesh/D059912?mesh_terms=Graft+Rejection&page=2#section-facteurs de risque" } ] }, { "@type": "FAQPage", "mainEntity": [ { "@type": "Question", "name": "Comment détecte-t-on l'antigène HLA-B37 ?", "position": 1, "acceptedAnswer": { "@type": "Answer", "text": "Par des tests de typage HLA, souvent réalisés sur des échantillons de sang." } }, { "@type": "Question", "name": "Quels tests sont utilisés pour le HLA-B37 ?", "position": 2, "acceptedAnswer": { "@type": "Answer", "text": "Les tests de compatibilité tissulaire et les analyses de sang sont courants." } }, { "@type": "Question", "name": "Le HLA-B37 est-il associé à des maladies spécifiques ?", "position": 3, "acceptedAnswer": { "@type": "Answer", "text": "Oui, il est lié à certaines maladies auto-immunes et à des réactions de greffe." } }, { "@type": "Question", "name": "Qui doit se faire tester pour HLA-B37 ?", "position": 4, "acceptedAnswer": { "@type": "Answer", "text": "Les personnes ayant des antécédents familiaux de maladies auto-immunes ou nécessitant une greffe." } }, { "@type": "Question", "name": "Quelle est l'importance du HLA-B37 dans le diagnostic ?", "position": 5, "acceptedAnswer": { "@type": "Answer", "text": "Il aide à évaluer la compatibilité pour les greffes et à identifier des risques de maladies." } }, { "@type": "Question", "name": "Quels symptômes sont liés à HLA-B37 ?", "position": 6, "acceptedAnswer": { "@type": "Answer", "text": "Les symptômes varient selon les maladies associées, comme la fatigue ou des douleurs articulaires." } }, { "@type": "Question", "name": "HLA-B37 cause-t-il des symptômes directs ?", "position": 7, "acceptedAnswer": { "@type": "Answer", "text": "Non, il n'y a pas de symptômes directs, mais il est associé à des maladies symptomatiques." } }, { "@type": "Question", "name": "Peut-on avoir des symptômes sans HLA-B37 ?", "position": 8, "acceptedAnswer": { "@type": "Answer", "text": "Oui, de nombreuses maladies auto-immunes peuvent survenir sans HLA-B37." } }, { "@type": "Question", "name": "Les symptômes varient selon les individus ?", "position": 9, "acceptedAnswer": { "@type": "Answer", "text": "Oui, la réponse immunitaire et les symptômes peuvent varier d'une personne à l'autre." } }, { "@type": "Question", "name": "HLA-B37 est-il lié à des symptômes allergiques ?", "position": 10, "acceptedAnswer": { "@type": "Answer", "text": "Non, HLA-B37 est principalement associé à des maladies auto-immunes, pas aux allergies." } }, { "@type": "Question", "name": "Peut-on prévenir les maladies liées à HLA-B37 ?", "position": 11, "acceptedAnswer": { "@type": "Answer", "text": "La prévention est difficile, mais un suivi médical régulier peut aider à détecter précocement." } }, { "@type": "Question", "name": "Y a-t-il des mesures préventives spécifiques ?", "position": 12, "acceptedAnswer": { "@type": "Answer", "text": "Adopter un mode de vie sain et éviter les facteurs de risque peut être bénéfique." } }, { "@type": "Question", "name": "Les tests génétiques aident-ils à la prévention ?", "position": 13, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les tests peuvent identifier les personnes à risque et permettre une surveillance." } }, { "@type": "Question", "name": "Les vaccinations sont-elles utiles ?", "position": 14, "acceptedAnswer": { "@type": "Answer", "text": "Les vaccinations peuvent aider à prévenir certaines infections, mais pas directement liées à HLA-B37." } }, { "@type": "Question", "name": "Le stress influence-t-il les maladies liées à HLA-B37 ?", "position": 15, "acceptedAnswer": { "@type": "Answer", "text": "Le stress peut aggraver les symptômes des maladies auto-immunes, donc sa gestion est importante." } }, { "@type": "Question", "name": "Quels traitements sont disponibles pour les maladies liées à HLA-B37 ?", "position": 16, "acceptedAnswer": { "@type": "Answer", "text": "Les traitements incluent des immunosuppresseurs et des thérapies ciblées selon la maladie." } }, { "@type": "Question", "name": "Le traitement dépend-il du type de maladie ?", "position": 17, "acceptedAnswer": { "@type": "Answer", "text": "Oui, le traitement est adapté en fonction de la maladie auto-immune spécifique." } }, { "@type": "Question", "name": "Les greffes sont-elles affectées par HLA-B37 ?", "position": 18, "acceptedAnswer": { "@type": "Answer", "text": "Oui, HLA-B37 influence la compatibilité et le risque de rejet lors des greffes." } }, { "@type": "Question", "name": "Y a-t-il des traitements préventifs pour HLA-B37 ?", "position": 19, "acceptedAnswer": { "@type": "Answer", "text": "Il n'existe pas de traitement préventif spécifique, mais un suivi médical est conseillé." } }, { "@type": "Question", "name": "Les traitements sont-ils efficaces ?", "position": 20, "acceptedAnswer": { "@type": "Answer", "text": "L'efficacité varie selon la maladie et la réponse individuelle au traitement." } }, { "@type": "Question", "name": "Quelles complications peuvent survenir avec HLA-B37 ?", "position": 21, "acceptedAnswer": { "@type": "Answer", "text": "Des complications incluent le rejet de greffe et des exacerbations de maladies auto-immunes." } }, { "@type": "Question", "name": "HLA-B37 augmente-t-il le risque de cancer ?", "position": 22, "acceptedAnswer": { "@type": "Answer", "text": "Certaines études suggèrent un risque accru de cancers associés aux maladies auto-immunes." } }, { "@type": "Question", "name": "Les complications sont-elles réversibles ?", "position": 23, "acceptedAnswer": { "@type": "Answer", "text": "Certaines complications peuvent être gérées, mais d'autres peuvent être permanentes." } }, { "@type": "Question", "name": "Comment prévenir les complications liées à HLA-B37 ?", "position": 24, "acceptedAnswer": { "@type": "Answer", "text": "Un suivi médical régulier et un traitement approprié peuvent aider à prévenir les complications." } }, { "@type": "Question", "name": "Les complications varient-elles selon les individus ?", "position": 25, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les complications peuvent varier en fonction de la génétique et de l'état de santé général." } }, { "@type": "Question", "name": "Quels sont les facteurs de risque pour HLA-B37 ?", "position": 26, "acceptedAnswer": { "@type": "Answer", "text": "Les antécédents familiaux de maladies auto-immunes et certains facteurs environnementaux." } }, { "@type": "Question", "name": "L'âge influence-t-il le risque lié à HLA-B37 ?", "position": 27, "acceptedAnswer": { "@type": "Answer", "text": "Oui, certaines maladies auto-immunes liées à HLA-B37 apparaissent plus fréquemment chez les jeunes adultes." } }, { "@type": "Question", "name": "Le sexe joue-t-il un rôle dans le risque ?", "position": 28, "acceptedAnswer": { "@type": "Answer", "text": "Oui, certaines maladies auto-immunes sont plus fréquentes chez les femmes que chez les hommes." } }, { "@type": "Question", "name": "Les infections augmentent-elles le risque ?", "position": 29, "acceptedAnswer": { "@type": "Answer", "text": "Certaines infections peuvent déclencher des maladies auto-immunes chez les individus prédisposés." } }, { "@type": "Question", "name": "Le mode de vie influence-t-il le risque ?", "position": 30, "acceptedAnswer": { "@type": "Answer", "text": "Oui, un mode de vie malsain peut augmenter le risque de développer des maladies auto-immunes." } } ] } ] }

Sources (9835 au total)

Mesh excision secondary to spondylodiscitis after colposacropexy graft rejection: a step by step video.

Spondylodiscitis secondary to colposacropexy is an extremely rare entity. Infection and mesh rejection are the main causes. Removal of the mesh is essential for patient's recovery and it can be a very... A 72-year-old woman presented with severe low back pain in the context of a recent colposacropexy. Magnetic resonance imaging was performed and spondylodiscitis secondary to prolapse correction surger... Spondylodiscitis secondary to colposacropexy should be suspected when the patient starts with moderate lumbar pain and is not correctly controlled with first-level analgesia. Infection or mesh rejecti...

Effect of cardiac graft rejection on semilunar valve function: implications for heart valve transplantation.

The treatment of neonates with unrepairable heart valve dysfunction remains an unsolved problem because there are no growing heart valve replacements. Heart valve transplantation is a potential approa... We included children who underwent orthotopic heart transplantation at our institution and experienced at least one episode of rejection between 1/1/2010 and 1/1/2020. Semilunar valve function was ana... Included were a total of 31 episodes of rejection. All patients had either no (27) or trivial (4) aortic insufficiency prior to rejection. One patient developed mild aortic insufficiency during a reje... This study demonstrated that there was no echocardiographic evidence of change in semilunar valve function during episodes of rejection in patient with heart transplants. These findings indicate that ...

Outcomes after reversed corneal graft rejection: a report from the European VISICORT project.

This study aims to describe the outcome of corneal grafts, both low risk and high risk, after successfully reversed immunological rejection.... Datasets on reversed rejection episodes in penetrating and endothelial keratoplasties between 2014 and 2019 (n=876) were extracted from the Adverse Immune Signatures and their Prevention in Corneal Tr... Fourty-seven (52%) out of a total of 91 identified rejection episodes were successfully reversed and were available for analysis (23 penetrating and 24 endothelial keratoplasties). No statistically si... The outcome of corneal grafts that survive immunological rejection may be clinically indistinguishable from the state before immunological rejection, irrespective of graft type and risk status. These ...

Isolated Hepatic Chronic Ductopenic Rejection Requiring Liver Retransplant in the Absence of Kidney Graft Rejection After Combined Liver-Kidney Transplant: A Case Report.

The liver is considered the most immunotolerant organ among all solid-organ transplants. Liver transplant recipients have a lower incidence of rejection and better outcomes after episodes of rejection...

Incidence of Graft Rejection in Descemet Membrane Endothelial Keratoplasty After COVID-19 mRNA Vaccination.

The aim of this study was to investigate the Descemet membrane endothelial keratoplasty (DMEK) rejection rate after COVID-19 vaccination with an mRNA vaccine.... This was a multicenter, retrospective cohort study. A total of 198 patients who underwent DMEK between January 2006 and December 2020 were divided into 2 cohorts: consecutive patients who received at ... Six rejection episodes were observed in 198 patients (124 nonvaccinated and 74 vaccinated patients), with 1 occurring in the nonvaccinated group and 5 in the vaccinated group. In the univariate model,... This study suggests that there may be a higher rejection rate after COVID-19 vaccination in patients who underwent DMEK. Patients should be warned of the rejection risk and its typical symptoms before...

CYP3A5 Expressor Genotype of the Transplanted Kidney Increases the Risk of Preterm Graft Loss and Acute Rejection.

Tacrolimus is metabolized mainly in the liver by the CYP3A enzyme family, with a particularly well-documented role of CYP3A5. CYP3A5 is also expressed in the renal tissue and is present in the transpl... A retrospective cohort study including 207 patients who received kidney grafts from 110 deceased donors was conducted at a single Central European Center. Tissue samples from all donors were studied f... Recipients who received kidneys from CYP3A5 expressors (n = 24) were at significantly higher risk of death-censored graft loss within 5-year follow-up (adjusted HR, 95% CI: 6.82, 2.01-23.12; p = 0.002... Donor CYP3A5 expressor status is associated with worse renal graft survival and a higher risk of acute rejection. Determination of donor CYP3A5 genotype is a potentially useful tool that may improve k...

Rejection and graft outcomes in kidney transplant recipients with and without angiotensin II receptor type 1 antibodies.

Angiotensin II type 1 receptor antibody (AT1R Ab) is a non-Human Leucocyte Antigen (HLA) antibody that is maybe associated with early severe kidney transplant rejection and worse graft outcomes. This ... We performed a retrospective analysis of all adult kidney transplant recipients in an Australian centre who had an AT1R Ab test between 1 January 2015 to 30 June 2020. AT1R Ab positive patients were c... Of 965 kidney transplants that were performed during the study period, 73 patients had AT1R Ab tested; 16 (22%) were positive and 57(78%) were negative. Positive patients were on average younger and h... The study found no evidence that AT1R Ab is associated with rejection type, severity or worse graft function. Future studies should assess its relationship with graft outcomes to help complement immun...

Native T1 mapping detects both acute clinical rejection and graft dysfunction in pediatric heart transplant patients.

Cardiovascular magnetic resonance (CMR) is emerging as an important tool for cardiac allograft assessment. Native T1 mapping may add value in identifying rejection and in assessing graft dysfunction a... Fifty cases with simultaneous EMB, right heart catheterization, and 1.5 T CMR with breath-held T1 mapping via modified Look-Locker inversion recovery (MOLLI) in 8 short-axis slices and subsequent quan... Peak and mean T1 values were significantly associated with acute rejection, with a monotonic trend observed with increased grade of rejection. Texture analysis demonstrated greater spatial heterogenei... In pediatric heart transplant patients, native T1 values identify acute rejection requiring treatment and may identify graft dysfunction. CMR shows promise as an important tool for evaluation of cardi...