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"description": "Quelles complications peuvent survenir avec HLA-B37 ?\nHLA-B37 augmente-t-il le risque de cancer ?\nLes complications sont-elles réversibles ?\nComment prévenir les complications liées à HLA-B37 ?\nLes complications varient-elles selon les individus ?",
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"description": "Quels sont les facteurs de risque pour HLA-B37 ?\nL'âge influence-t-il le risque lié à HLA-B37 ?\nLe sexe joue-t-il un rôle dans le risque ?\nLes infections augmentent-elles le risque ?\nLe mode de vie influence-t-il le risque ?",
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"@type": "Question",
"name": "Comment détecte-t-on l'antigène HLA-B37 ?",
"position": 1,
"acceptedAnswer": {
"@type": "Answer",
"text": "Par des tests de typage HLA, souvent réalisés sur des échantillons de sang."
}
},
{
"@type": "Question",
"name": "Quels tests sont utilisés pour le HLA-B37 ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les tests de compatibilité tissulaire et les analyses de sang sont courants."
}
},
{
"@type": "Question",
"name": "Le HLA-B37 est-il associé à des maladies spécifiques ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, il est lié à certaines maladies auto-immunes et à des réactions de greffe."
}
},
{
"@type": "Question",
"name": "Qui doit se faire tester pour HLA-B37 ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les personnes ayant des antécédents familiaux de maladies auto-immunes ou nécessitant une greffe."
}
},
{
"@type": "Question",
"name": "Quelle est l'importance du HLA-B37 dans le diagnostic ?",
"position": 5,
"acceptedAnswer": {
"@type": "Answer",
"text": "Il aide à évaluer la compatibilité pour les greffes et à identifier des risques de maladies."
}
},
{
"@type": "Question",
"name": "Quels symptômes sont liés à HLA-B37 ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les symptômes varient selon les maladies associées, comme la fatigue ou des douleurs articulaires."
}
},
{
"@type": "Question",
"name": "HLA-B37 cause-t-il des symptômes directs ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Non, il n'y a pas de symptômes directs, mais il est associé à des maladies symptomatiques."
}
},
{
"@type": "Question",
"name": "Peut-on avoir des symptômes sans HLA-B37 ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, de nombreuses maladies auto-immunes peuvent survenir sans HLA-B37."
}
},
{
"@type": "Question",
"name": "Les symptômes varient selon les individus ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, la réponse immunitaire et les symptômes peuvent varier d'une personne à l'autre."
}
},
{
"@type": "Question",
"name": "HLA-B37 est-il lié à des symptômes allergiques ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Non, HLA-B37 est principalement associé à des maladies auto-immunes, pas aux allergies."
}
},
{
"@type": "Question",
"name": "Peut-on prévenir les maladies liées à HLA-B37 ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "La prévention est difficile, mais un suivi médical régulier peut aider à détecter précocement."
}
},
{
"@type": "Question",
"name": "Y a-t-il des mesures préventives spécifiques ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Adopter un mode de vie sain et éviter les facteurs de risque peut être bénéfique."
}
},
{
"@type": "Question",
"name": "Les tests génétiques aident-ils à la prévention ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les tests peuvent identifier les personnes à risque et permettre une surveillance."
}
},
{
"@type": "Question",
"name": "Les vaccinations sont-elles utiles ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les vaccinations peuvent aider à prévenir certaines infections, mais pas directement liées à HLA-B37."
}
},
{
"@type": "Question",
"name": "Le stress influence-t-il les maladies liées à HLA-B37 ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le stress peut aggraver les symptômes des maladies auto-immunes, donc sa gestion est importante."
}
},
{
"@type": "Question",
"name": "Quels traitements sont disponibles pour les maladies liées à HLA-B37 ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les traitements incluent des immunosuppresseurs et des thérapies ciblées selon la maladie."
}
},
{
"@type": "Question",
"name": "Le traitement dépend-il du type de maladie ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le traitement est adapté en fonction de la maladie auto-immune spécifique."
}
},
{
"@type": "Question",
"name": "Les greffes sont-elles affectées par HLA-B37 ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, HLA-B37 influence la compatibilité et le risque de rejet lors des greffes."
}
},
{
"@type": "Question",
"name": "Y a-t-il des traitements préventifs pour HLA-B37 ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Il n'existe pas de traitement préventif spécifique, mais un suivi médical est conseillé."
}
},
{
"@type": "Question",
"name": "Les traitements sont-ils efficaces ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'efficacité varie selon la maladie et la réponse individuelle au traitement."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir avec HLA-B37 ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des complications incluent le rejet de greffe et des exacerbations de maladies auto-immunes."
}
},
{
"@type": "Question",
"name": "HLA-B37 augmente-t-il le risque de cancer ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines études suggèrent un risque accru de cancers associés aux maladies auto-immunes."
}
},
{
"@type": "Question",
"name": "Les complications sont-elles réversibles ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines complications peuvent être gérées, mais d'autres peuvent être permanentes."
}
},
{
"@type": "Question",
"name": "Comment prévenir les complications liées à HLA-B37 ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un suivi médical régulier et un traitement approprié peuvent aider à prévenir les complications."
}
},
{
"@type": "Question",
"name": "Les complications varient-elles selon les individus ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les complications peuvent varier en fonction de la génétique et de l'état de santé général."
}
},
{
"@type": "Question",
"name": "Quels sont les facteurs de risque pour HLA-B37 ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les antécédents familiaux de maladies auto-immunes et certains facteurs environnementaux."
}
},
{
"@type": "Question",
"name": "L'âge influence-t-il le risque lié à HLA-B37 ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certaines maladies auto-immunes liées à HLA-B37 apparaissent plus fréquemment chez les jeunes adultes."
}
},
{
"@type": "Question",
"name": "Le sexe joue-t-il un rôle dans le risque ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certaines maladies auto-immunes sont plus fréquentes chez les femmes que chez les hommes."
}
},
{
"@type": "Question",
"name": "Les infections augmentent-elles le risque ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines infections peuvent déclencher des maladies auto-immunes chez les individus prédisposés."
}
},
{
"@type": "Question",
"name": "Le mode de vie influence-t-il le risque ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, un mode de vie malsain peut augmenter le risque de développer des maladies auto-immunes."
}
}
]
}
]
}
Vitamin D is an essential nutrient that plays a vital role in bone health and musculoskeletal development. The aim of this narrative review is to present up-to-date information about the impact of vit...
The objective of this article is to evaluate the response to 6000 IU oral cholecalciferol (OC) treatment in children with chronic liver disease (CLD) and 25(OH)D deficiency....
This historical cohort included non-transplanted CLD patients younger than 18 years old, which were analyzed for serum 25(OH)D, liver function, bone metabolism, Child-Pugh classification, and anthropo...
We studied 96 patients, of which 57.2% had biliary atresia. The prevalence of 25(OH)D deficiency was 67.7% (65/96). These patients were younger ( P < 0.001), had higher Child-Pugh scores ( P < 0.001),...
Despite an increase in 25(OH)D and decrease in PTH levels, 6000 IU/day of OC was not sufficient to restore 25(OH)D deficiency in most of the patients in this study....
Given the sparse data on vitamin D status in pediatric COVID-19, we investigated whether vitamin D deficiency could be a risk factor for susceptibility to COVID-19 in Egyptian children and adolescents...
One hundred and eighty patients diagnosed to have COVID-19 and 200 matched control children and adolescents were recruited. Patients were laboratory confirmed as SARS-CoV-2 positive by real-time RT-PC...
Ninety-four patients (52%) had low vitamin D levels with 74 (41%) being deficient and 20 (11%) had vitamin D insufficiency. Vitamin D deficiency was associated with 2.6-fold increased risk for COVID-1...
Vitamin D deficiency and VDR Fok I polymorphism may constitute independent risk factors for susceptibility to COVID-19 in Egyptian children and adolescents....
Vitamin D deficiency could be a modifiable risk factor for COVID-19 in children and adolescents because of its immune-modulatory action. To our knowledge, ours is the first such study to investigate t...
Parathyroid hormone (PTH) is an indirect functional indicator of vitamin D status. Risk of vitamin D deficiency, assessed using circulating 25-hydroxyvitamin D (25(OH)D), is defined as <30 nmol/L by t...
To test PTH concentrations and the odds for elevated values according to vitamin D deficiency cut-points (<30 nmol/L, or <25 nmol/L) in newborn infants....
Healthy term-born infants (n = 858) were recruited from Montreal, Canada (2016-2019). Obstetric data were obtained from medical records, and demographic factors surveyed. Immunoassays were used to mea...
Infants (50.2 % female) were 39.6 ± 1.0 weeks gestational age (mean ± SD), and 3.41 ± 0.38 kg. Median serum 25(OH)D was 45.4 (IQR 23.2) nmol/L; 20.5 % had serum 25(OH)D < 30 nmol/L, and 12.4 % <25 nmo...
Based on this study, the definition of vitamin D deficiency relative to bone health as set by the National Academy of Medicine (<30 nmol/L) exceeds the threshold at which PTH is elevated in newborn in...
Vitamin D deficiency (VDD) is common among young women and causes various health problems, including those that occur during pregnancy and childbirth. Thus, we investigated the risk factors for VDD in...
A cross-sectional study, using the following factors for multivariate logistic regression analysis to create the ViDDPreS score: residential area, season, cumulative ambient ultraviolet-B irradiation,...
Four regions (Hokkaido/Tohoku, Kanto, Chubu/Kinki/Shikoku and Kyushu/Okinawa) in Japan....
Five hundred and eighty-three healthy women aged 18-40 years....
In the development set, the VDD group (68·4 %) had higher proportions of the following variables than the non-VDD group: residential area outside the Kanto region; blood samples obtained in winter; lo...
We identified the risk factors for VDD in young Japanese women and developed a simple risk scoring system that enables us to assess VDD risk and aid in the development of appropriate prevention and tr...
The aim of this study was to evaluate serum 25(OH)D concentrations in the homebound elderly people and relate them to level of dementia, nutritional risk, and route of dietary administration....
This is a cross-sectional study involving 207 bedridden elderly people assisted by the Home Care Service in the city of Santo André - SP, from June to December 2016. The following factors were evaluat...
The mean age of the elderly people was 81.6 (9.2) years. Deficiency of 25(OH)D was observed in 76.3% of the elderly people. There was an inverse correlation between serum concentrations of 25(OH)D: pa...
Bedridden households showed high prevalence of vitamin D deficiency without association with nutritional risk and level of dementia. Oral diet was associated with vitamin D deficiency, possibly due to...
There is biological and epidemiological evidence supporting a role for vitamin D in the respiratory system, and vitamin D deficiency (VDD) may be associated with poor health outcomes in people with ch...
The prevalence of VDD in people with COPD may be underestimated. Treatment of severe VDD [serum 25(OH)D3 < 10 ng/ml] may reduce the risk of COPD exacerbations. Vitamin D supplementation may also impro...
Although there are many known associations between vitamin D and COPD outcomes, the causal nature of these associations and the precise benefits of vitamin D supplementation remain unclear. High-quali...
Dengue fever is a vector-borne disease with an estimate of 390 million persons getting the infection each year with a significant public health impact. It has been reported DENV patients with vitamin ...
In this case control study the association of the vitamin D levels with age, gender and...
Four hundred dengue fever patients with...
The present study proposes that vitamin D deficiency in dengue fever patients coinfected with...
Vitamin D deficiency is a condition with different causes. It is associated with numerous comorbidities such as autoimmune diseases, bone diseases, cancer, cardiovascular diseases, neurodegenerative d...
This retrospective study analyzed the prevalence of vitamin D deficiency (serum 25-hydroxyvitamin D [25(OH)D] < 12 ng/ml) amongst selected Austrian nursing home seniors. It also examined whether demog...
A total of 106 seniors (22,2%) suffered from a manifest vitamin D deficiency. The vitamin D level of the men was significantly lower than the level of the women (22.9 ± 12.6 ng/ml vs. 26.2 ± 14.8 ng/m...
In summary, it can be said that the prevalence of vitamin D deficiency among nursing home residents is considerably high. Inadequate vitamin D levels were often associated with reduced calcium levels....
Tonsillitis is defined as an inflammation of the tonsils characterized by signs of tonsillar erythema and exudates and recurrent tonsillitis is at least 7 episodes of acute tonsillitis in a year, or a...
A single centre prospective, cross sectional analytical study was conducted from 2021 June to 2022 March in Department of ENT and Head and Neck surgery in Kathmandu Medical College Teaching Hospital. ...
78.8% of patients with tonsillitis had low level of serum Vitamin D (less than 30ng/ml) and 21.2% had optimal level of serum Vitamin D (more than 30ng/ml). The incidence of recurrent tonsillitis was 4...
The low serum level of Vitamin D was found to be associated with recurrent episodes of tonsillitis....