questionsmedicales.fr
Facteurs biologiques
Protéines et peptides de signalisation intercellulaire
Cytokines
Interleukines
Interleukine-27
Interleukine-27 : Questions médicales fréquentes
Termes MeSH sélectionnés :
Diagnostic
5
Interleukine-27
Cytokines
Cytométrie en flux
Tests immunologiques
Maladies auto-immunes
Inflammation
Inflammation
Gravité des maladies
Symptômes
5
Douleurs articulaires
Maladies inflammatoires
Symptômes respiratoires
Maladies pulmonaires
Symptômes neurologiques
Conditions neurologiques
Prévention
5
Modes de vie sains
Gestion du stress
Alimentation
Inflammation
Exercice physique
Santé immunitaire
Traitements
5
Thérapies biologiques
Maladies auto-immunes
Médicaments anti-inflammatoires
Modulation
Efficacité des traitements
Réponse immunitaire
Complications
5
Complications
Maladies auto-immunes
Maladies chroniques
Arthrite
Cancer
Croissance tumorale
Troubles neurologiques
Sclérose en plaques
Facteurs de risque
5
Maladies auto-immunes
Facteurs de risque
Alimentation
Régimes alimentaires
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"name": "Diagnostic",
"headline": "Diagnostic sur Interleukine-27",
"description": "Comment mesurer l'IL-27 dans le sang ?\nQuels tests sont utilisés pour évaluer l'IL-27 ?\nL'IL-27 est-elle mesurée dans des maladies spécifiques ?\nQuels biomarqueurs sont associés à l'IL-27 ?\nL'IL-27 peut-elle être un indicateur de gravité ?",
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"@type": "Question",
"name": "Comment mesurer l'IL-27 dans le sang ?",
"position": 1,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'IL-27 peut être mesurée par des tests ELISA dans des échantillons de sérum."
}
},
{
"@type": "Question",
"name": "Quels tests sont utilisés pour évaluer l'IL-27 ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des tests immunologiques comme l'ELISA et la cytométrie en flux sont utilisés."
}
},
{
"@type": "Question",
"name": "L'IL-27 est-elle mesurée dans des maladies spécifiques ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'IL-27 est souvent mesurée dans des maladies auto-immunes et inflammatoires."
}
},
{
"@type": "Question",
"name": "Quels biomarqueurs sont associés à l'IL-27 ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'IL-27 est souvent associée à d'autres cytokines comme l'IL-6 et l'IL-10."
}
},
{
"@type": "Question",
"name": "L'IL-27 peut-elle être un indicateur de gravité ?",
"position": 5,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des niveaux élevés d'IL-27 peuvent indiquer une inflammation sévère."
}
},
{
"@type": "Question",
"name": "Quels symptômes sont liés à une élévation de l'IL-27 ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une élévation de l'IL-27 peut entraîner des symptômes d'inflammation comme la fièvre."
}
},
{
"@type": "Question",
"name": "L'IL-27 est-elle liée à des douleurs articulaires ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'IL-27 peut contribuer à des douleurs articulaires dans les maladies inflammatoires."
}
},
{
"@type": "Question",
"name": "Quels signes cliniques sont associés à l'IL-27 ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les signes cliniques incluent fatigue, douleurs et symptômes systémiques d'inflammation."
}
},
{
"@type": "Question",
"name": "L'IL-27 influence-t-elle les symptômes respiratoires ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'IL-27 peut exacerber les symptômes respiratoires dans certaines maladies pulmonaires."
}
},
{
"@type": "Question",
"name": "Y a-t-il des symptômes neurologiques liés à l'IL-27 ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des niveaux élevés d'IL-27 peuvent être associés à des symptômes neurologiques dans certaines conditions."
}
},
{
"@type": "Question",
"name": "Peut-on prévenir l'élévation de l'IL-27 ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des modes de vie sains et une gestion du stress peuvent aider à prévenir l'élévation de l'IL-27."
}
},
{
"@type": "Question",
"name": "Y a-t-il des vaccins liés à l'IL-27 ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Actuellement, il n'existe pas de vaccins spécifiquement ciblant l'IL-27."
}
},
{
"@type": "Question",
"name": "Comment l'alimentation influence-t-elle l'IL-27 ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une alimentation anti-inflammatoire peut aider à réguler les niveaux d'IL-27."
}
},
{
"@type": "Question",
"name": "L'exercice physique affecte-t-il l'IL-27 ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'exercice régulier peut réduire les niveaux d'IL-27 et améliorer la santé immunitaire."
}
},
{
"@type": "Question",
"name": "Le sommeil influence-t-il l'IL-27 ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un sommeil adéquat est crucial pour maintenir des niveaux sains d'IL-27 et une bonne santé."
}
},
{
"@type": "Question",
"name": "Quels traitements ciblent l'IL-27 ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des thérapies biologiques ciblant l'IL-27 sont en développement pour les maladies auto-immunes."
}
},
{
"@type": "Question",
"name": "L'IL-27 peut-elle être inhibée ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des inhibiteurs spécifiques de l'IL-27 sont à l'étude pour réduire l'inflammation."
}
},
{
"@type": "Question",
"name": "Quels médicaments affectent l'IL-27 ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certains médicaments anti-inflammatoires peuvent moduler les niveaux d'IL-27."
}
},
{
"@type": "Question",
"name": "L'IL-27 est-elle une cible pour l'immunothérapie ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'IL-27 est une cible potentielle pour l'immunothérapie dans le cancer."
}
},
{
"@type": "Question",
"name": "Comment l'IL-27 influence-t-elle les traitements ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'IL-27 peut influencer l'efficacité des traitements en modulant la réponse immunitaire."
}
},
{
"@type": "Question",
"name": "Quelles complications sont liées à l'IL-27 ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des niveaux élevés d'IL-27 peuvent entraîner des complications dans les maladies auto-immunes."
}
},
{
"@type": "Question",
"name": "L'IL-27 est-elle impliquée dans des maladies chroniques ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'IL-27 est associée à des maladies chroniques comme l'arthrite et le lupus."
}
},
{
"@type": "Question",
"name": "Comment l'IL-27 affecte-t-elle le cancer ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'IL-27 peut avoir un rôle double dans le cancer, favorisant ou inhibant la croissance tumorale."
}
},
{
"@type": "Question",
"name": "Y a-t-il des risques d'infection liés à l'IL-27 ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des niveaux élevés d'IL-27 peuvent augmenter le risque d'infections en modulant l'immunité."
}
},
{
"@type": "Question",
"name": "L'IL-27 est-elle liée à des troubles neurologiques ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des niveaux anormaux d'IL-27 peuvent être associés à des troubles neurologiques comme la sclérose en plaques."
}
},
{
"@type": "Question",
"name": "Quels facteurs augmentent l'IL-27 ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le stress, l'obésité et les infections chroniques peuvent augmenter les niveaux d'IL-27."
}
},
{
"@type": "Question",
"name": "L'âge influence-t-il les niveaux d'IL-27 ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les niveaux d'IL-27 peuvent augmenter avec l'âge, affectant la réponse immunitaire."
}
},
{
"@type": "Question",
"name": "Les maladies auto-immunes sont-elles un facteur de risque ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les personnes atteintes de maladies auto-immunes présentent souvent des niveaux élevés d'IL-27."
}
},
{
"@type": "Question",
"name": "Le tabagisme affecte-t-il l'IL-27 ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le tabagisme peut augmenter les niveaux d'IL-27 et aggraver l'inflammation."
}
},
{
"@type": "Question",
"name": "Y a-t-il un lien entre l'IL-27 et l'alimentation ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines habitudes alimentaires peuvent influencer les niveaux d'IL-27, notamment les régimes riches en sucres."
}
}
]
}
]
}
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 18/02/2025
Contenu vérifié selon les dernières recommandations médicales
4 publications dans cette catégorie
Affiliations :
Department of Microbiology, Immunology, & Cell Biology, West Virginia University School of Medicine, Morgantown, WV, United States.
Vaccine Development Center, West Virginia University Health Sciences Center, Morgantown, WV, United States.
Publications dans "Interleukine-27" :
4 publications dans cette catégorie
Affiliations :
Laboratory of Human Retrovirology and Immunoinformatics, Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA.
Publications dans "Interleukine-27" :
3 publications dans cette catégorie
Affiliations :
Department of Microbiology, Immunology, & Cell Biology, West Virginia University School of Medicine, Morgantown, WV, United States.
Vaccine Development Center, West Virginia University Health Sciences Center, Morgantown, WV, United States.
Publications dans "Interleukine-27" :
3 publications dans cette catégorie
Affiliations :
Department of Microbiology, Immunology, & Cell Biology, West Virginia University School of Medicine, Morgantown, WV, United States.
Publications dans "Interleukine-27" :
3 publications dans cette catégorie
Affiliations :
Laboratory of Human Retrovirology and Immunoinformatics, Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA.
Publications dans "Interleukine-27" :
3 publications dans cette catégorie
Affiliations :
Laboratory of Human Retrovirology and Immunoinformatics, Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA.
Publications dans "Interleukine-27" :
3 publications dans cette catégorie
Affiliations :
Laboratory of Human Retrovirology and Immunoinformatics, Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA.
Publications dans "Interleukine-27" :
3 publications dans cette catégorie
Affiliations :
Laboratory of Human Retrovirology and Immunoinformatics, Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA.
Publications dans "Interleukine-27" :
3 publications dans cette catégorie
Affiliations :
Laboratory of Human Retrovirology and Immunoinformatics, Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA.
Publications dans "Interleukine-27" :
3 publications dans cette catégorie
Affiliations :
Laboratory of Human Retrovirology and Immunoinformatics, Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA.
Publications dans "Interleukine-27" :
3 publications dans cette catégorie
Affiliations :
Department of Microbiology, Immunology, & Cell Biology, West Virginia University School of Medicine, Morgantown, WV, USA.
Vaccine Development Center at West Virginia University Health Sciences Center, Morgantown, WV, USA.
Publications dans "Interleukine-27" :
3 publications dans cette catégorie
Affiliations :
Department of Microbiology, Immunology, & Cell Biology, West Virginia University School of Medicine, Morgantown, WV, USA.
Publications dans "Interleukine-27" :
2 publications dans cette catégorie
Affiliations :
Department of Immunology, School of Medicine, Kerman University of Medical Sciences, Kerman, Iran.
Immunology of Infectious Diseases Research Center, Research Institute of Basic Medical Sciences, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
Publications dans "Interleukine-27" :
2 publications dans cette catégorie
Affiliations :
Immunology of Infectious Diseases Research Center, Research Institute of Basic Medical Sciences, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
Department of Haematology and Laboratory Sciences, School of Para-Medicine, Kerman University of Medical Sciences, Kerman, Iran.
Publications dans "Interleukine-27" :
2 publications dans cette catégorie
Affiliations :
National Centre for Cell Science, Pune, India.
Publications dans "Interleukine-27" :
2 publications dans cette catégorie
Affiliations :
National Centre for Cell Science, Pune, India.
Trident Academy of Creative Technology, Bhubaneswar, India.
Publications dans "Interleukine-27" :
2 publications dans cette catégorie
Affiliations :
Department of Biomedical and Molecular Sciences, Queen's University, Kingston, ON, Canada.
Publications dans "Interleukine-27" :
2 publications dans cette catégorie
Affiliations :
Department of Biomedical and Molecular Sciences, Queen's University, Kingston, ON, Canada.
Publications dans "Interleukine-27" :
2 publications dans cette catégorie
Affiliations :
Department of Neurology, Tianjin Medical University General Hospital Airport Hospital, Tianjin, China.
Publications dans "Interleukine-27" :
2 publications dans cette catégorie
Affiliations :
Department of Neonatology, Ministry of Education Key Laboratory of Child Development and Disorders, National Clinical Research Center for Child Health and Disorders, Chongqing Key Laboratory of Pediatrics, Children's Hospital of Chongqing Medical University, Chongqing 400014, China.
Publications dans "Interleukine-27" :
Increased vagal activity plays a prominent role in vasovagal syncope (VVS). The aim of this study was to characterize vagal function in VVS by evaluating the heart rate (HR) deceleration capacity (DC)...
A total of 188 consecutive VVS patients were enrolled in the study, of whom 129 had positive head-up tilt test (HUTT); 132 healthy participants were enrolled as controls. DC, DRs (DR2, i.e., episodes ...
Patients with VVS had higher DC (10.63 ± 2.1 vs. 6.58 ± 1.7 ms; P < 0.001) and lower minimum HR and DR6-10 than controls. No significant differences in DC or DR6-10 were found between the patients wit...
Compared to healthy controls, patients with VVS demonstrated distinct HR deceleration profiles between attacks, including overall higher DC and lower DR6-10....
We suggest a novel method for detecting mortality deceleration by adding a penalty to the log-likelihood function in a gamma-Gompertz setting. This is an alternative to traditional likelihood inferenc...
To investigate whether an association exists between deceleration and acceleration areas on continuous fetal cardiotocography (CTG) and neonatal encephalopathy (NE)....
A single center, retrospective case-control study was conducted to compare CTG characteristics of low-risk pregnancies (35 weeks of gestation or more), complicated by moderate to severe NE with two ma...
During the period between 2013 and 2019, we identified 95 cases of low-risk pregnancies that were complicated by moderate to severe NE in our center. Thirty-three (34.7%) deliveries were excluded, mos...
NE was significantly associated with increased total deceleration area, decreased total acceleration area, and a lower acceleration-to-deceleration ratio, independent of cord blood pH. Development of ...
Monitoring muscle damage in athletes assists not only coaches to adjust the training workload but also medical staff to prevent injury. Measuring blood myoglobin concentration can help evaluate muscle...
Whole blood samples from participants' fingertips were collected before the match (baseline) and at 2, 16, and 40 h after the match. Myoglobin concentrations were measured using the IA-100 compact imm...
The mean myoglobin concentration was significantly higher at 2 h than at the other time points (P<0.05), and decreased to baseline levels within 16 h post-match. The mean creatine kinase concentration...
Our findings indicate that myoglobin is a more sensitive marker of muscle damage than creatine kinase after football match-play. Monitoring myoglobin in athletes can aid in determining their recovery ...
Hypoxic-ischemic encephalopathy (HIE) is an important contributor to disability worldwide. The current cardiotocography (CTG) predictive value for neonatal outcome is limited....
To assess the association of intrapartum CTG deceleration and acceleration areas with early MRI cerebral pathology in infants with HIE....
Term and near-term low-risk pregnancies that resulted in HIE, treated with therapeutic hypothermia with sufficient CTG records from a single, tertiary hospital between 2013 and 2021 were enrolled. Acc...
A total of 77 infants were included in the final analysis. Significant associations between increased total acceleration area (p = 0.007) and between a higher acceleration-to-deceleration area ratio (...
In neonates treated for HIE, acceleration area and acceleration-to-deceleration ratio are associated with the risk of neonatal brain MRI abnormalities. To increase the role of these measurements as a ...
The current cardiotocography predictive value for neonatal outcome is limited. This study aimed to assess the association of intrapartum deceleration and acceleration areas with the degree of cerebral...
The aim of this review is to summarize the current scientific knowledge about acceleration and deceleration demands during football training....
A systematic search of three electronic databases (PubMed, SPORTDiscus, Web of Science) was performed to identify peer-reviewed relevant English-language articles, following PRISMA guidelines....
All acceleration and deceleration data were analyzed and organized into four categories: i) training drills variables (i.e. manipulated drills variables such as number of players in small-sided games)...
Different exercises elicit different demands and small-sided games presented higher acceleration and deceleration demands than circuit training and other running based drills. Furthermore, manipulatin...
Modern societies provide an abundance of opportunities, which could lead to acceleration and time poverty, thereby paradoxically limiting well-being. This study examines this issue using social distan...
This study aimed to investigate the acute effects of lower limb wearable resistance on maximal horizontal deceleration biomechanics, across two different assessments. Twenty recreationally trained tea...
A new functional mapping strategy based on targeting deceleration zones (DZs) has become one of the most commonly used strategies within the armamentarium of substrate-based ablation methods for ventr...
The purpose of this study was to analyze the evolution of DZs during ablation and their correlation with CMR....
Forty-two consecutive patients with scar-related VT undergoing ablation after CMR in Hospital Clinic (October 2018-December 2020) were included (median age 65.3 ± 11.8 years; 94.7% male; 73.7% ischemi...
Overall, 95 DZs were analyzed, 93.68% of which were correlated with CMR-CCs: 44.8% located in the middle segment and 55.2% located in the entrance/exit of the channel. Remapping was performed in 91.7%...
DZs are highly correlated with CMR-CCs. In addition, remapping can lead to the identification of hidden substrate initially not identified by electroanatomic mapping but detected by CMR....
Deceleration is considered a commonly practised means to assess Foetal Heart Rate (FHR) through visual inspection and interpretation of patterns in Cardiotocography (CTG). The precision of deceleratio...