questionsmedicales.fr
Facteurs biologiques
Protéines et peptides de signalisation intercellulaire
Cytokines
Interleukines
Interleukine-27
Interleukine-27 : Questions médicales fréquentes
Termes MeSH sélectionnés :
Mendelian Randomization Analysis
Diagnostic
5
Interleukine-27
Cytokines
Cytométrie en flux
Tests immunologiques
Maladies auto-immunes
Inflammation
Inflammation
Gravité des maladies
Symptômes
5
Douleurs articulaires
Maladies inflammatoires
Symptômes respiratoires
Maladies pulmonaires
Symptômes neurologiques
Conditions neurologiques
Prévention
5
Modes de vie sains
Gestion du stress
Alimentation
Inflammation
Exercice physique
Santé immunitaire
Traitements
5
Thérapies biologiques
Maladies auto-immunes
Médicaments anti-inflammatoires
Modulation
Efficacité des traitements
Réponse immunitaire
Complications
5
Complications
Maladies auto-immunes
Maladies chroniques
Arthrite
Cancer
Croissance tumorale
Troubles neurologiques
Sclérose en plaques
Facteurs de risque
5
Maladies auto-immunes
Facteurs de risque
Alimentation
Régimes alimentaires
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"name": "Diagnostic",
"headline": "Diagnostic sur Interleukine-27",
"description": "Comment mesurer l'IL-27 dans le sang ?\nQuels tests sont utilisés pour évaluer l'IL-27 ?\nL'IL-27 est-elle mesurée dans des maladies spécifiques ?\nQuels biomarqueurs sont associés à l'IL-27 ?\nL'IL-27 peut-elle être un indicateur de gravité ?",
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"@type": "Question",
"name": "Comment mesurer l'IL-27 dans le sang ?",
"position": 1,
"acceptedAnswer": {
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"text": "L'IL-27 peut être mesurée par des tests ELISA dans des échantillons de sérum."
}
},
{
"@type": "Question",
"name": "Quels tests sont utilisés pour évaluer l'IL-27 ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des tests immunologiques comme l'ELISA et la cytométrie en flux sont utilisés."
}
},
{
"@type": "Question",
"name": "L'IL-27 est-elle mesurée dans des maladies spécifiques ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'IL-27 est souvent mesurée dans des maladies auto-immunes et inflammatoires."
}
},
{
"@type": "Question",
"name": "Quels biomarqueurs sont associés à l'IL-27 ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'IL-27 est souvent associée à d'autres cytokines comme l'IL-6 et l'IL-10."
}
},
{
"@type": "Question",
"name": "L'IL-27 peut-elle être un indicateur de gravité ?",
"position": 5,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des niveaux élevés d'IL-27 peuvent indiquer une inflammation sévère."
}
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{
"@type": "Question",
"name": "Quels symptômes sont liés à une élévation de l'IL-27 ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une élévation de l'IL-27 peut entraîner des symptômes d'inflammation comme la fièvre."
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{
"@type": "Question",
"name": "L'IL-27 est-elle liée à des douleurs articulaires ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'IL-27 peut contribuer à des douleurs articulaires dans les maladies inflammatoires."
}
},
{
"@type": "Question",
"name": "Quels signes cliniques sont associés à l'IL-27 ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les signes cliniques incluent fatigue, douleurs et symptômes systémiques d'inflammation."
}
},
{
"@type": "Question",
"name": "L'IL-27 influence-t-elle les symptômes respiratoires ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'IL-27 peut exacerber les symptômes respiratoires dans certaines maladies pulmonaires."
}
},
{
"@type": "Question",
"name": "Y a-t-il des symptômes neurologiques liés à l'IL-27 ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des niveaux élevés d'IL-27 peuvent être associés à des symptômes neurologiques dans certaines conditions."
}
},
{
"@type": "Question",
"name": "Peut-on prévenir l'élévation de l'IL-27 ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des modes de vie sains et une gestion du stress peuvent aider à prévenir l'élévation de l'IL-27."
}
},
{
"@type": "Question",
"name": "Y a-t-il des vaccins liés à l'IL-27 ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Actuellement, il n'existe pas de vaccins spécifiquement ciblant l'IL-27."
}
},
{
"@type": "Question",
"name": "Comment l'alimentation influence-t-elle l'IL-27 ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une alimentation anti-inflammatoire peut aider à réguler les niveaux d'IL-27."
}
},
{
"@type": "Question",
"name": "L'exercice physique affecte-t-il l'IL-27 ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'exercice régulier peut réduire les niveaux d'IL-27 et améliorer la santé immunitaire."
}
},
{
"@type": "Question",
"name": "Le sommeil influence-t-il l'IL-27 ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un sommeil adéquat est crucial pour maintenir des niveaux sains d'IL-27 et une bonne santé."
}
},
{
"@type": "Question",
"name": "Quels traitements ciblent l'IL-27 ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des thérapies biologiques ciblant l'IL-27 sont en développement pour les maladies auto-immunes."
}
},
{
"@type": "Question",
"name": "L'IL-27 peut-elle être inhibée ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des inhibiteurs spécifiques de l'IL-27 sont à l'étude pour réduire l'inflammation."
}
},
{
"@type": "Question",
"name": "Quels médicaments affectent l'IL-27 ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certains médicaments anti-inflammatoires peuvent moduler les niveaux d'IL-27."
}
},
{
"@type": "Question",
"name": "L'IL-27 est-elle une cible pour l'immunothérapie ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'IL-27 est une cible potentielle pour l'immunothérapie dans le cancer."
}
},
{
"@type": "Question",
"name": "Comment l'IL-27 influence-t-elle les traitements ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'IL-27 peut influencer l'efficacité des traitements en modulant la réponse immunitaire."
}
},
{
"@type": "Question",
"name": "Quelles complications sont liées à l'IL-27 ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des niveaux élevés d'IL-27 peuvent entraîner des complications dans les maladies auto-immunes."
}
},
{
"@type": "Question",
"name": "L'IL-27 est-elle impliquée dans des maladies chroniques ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'IL-27 est associée à des maladies chroniques comme l'arthrite et le lupus."
}
},
{
"@type": "Question",
"name": "Comment l'IL-27 affecte-t-elle le cancer ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'IL-27 peut avoir un rôle double dans le cancer, favorisant ou inhibant la croissance tumorale."
}
},
{
"@type": "Question",
"name": "Y a-t-il des risques d'infection liés à l'IL-27 ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des niveaux élevés d'IL-27 peuvent augmenter le risque d'infections en modulant l'immunité."
}
},
{
"@type": "Question",
"name": "L'IL-27 est-elle liée à des troubles neurologiques ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des niveaux anormaux d'IL-27 peuvent être associés à des troubles neurologiques comme la sclérose en plaques."
}
},
{
"@type": "Question",
"name": "Quels facteurs augmentent l'IL-27 ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le stress, l'obésité et les infections chroniques peuvent augmenter les niveaux d'IL-27."
}
},
{
"@type": "Question",
"name": "L'âge influence-t-il les niveaux d'IL-27 ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les niveaux d'IL-27 peuvent augmenter avec l'âge, affectant la réponse immunitaire."
}
},
{
"@type": "Question",
"name": "Les maladies auto-immunes sont-elles un facteur de risque ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les personnes atteintes de maladies auto-immunes présentent souvent des niveaux élevés d'IL-27."
}
},
{
"@type": "Question",
"name": "Le tabagisme affecte-t-il l'IL-27 ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le tabagisme peut augmenter les niveaux d'IL-27 et aggraver l'inflammation."
}
},
{
"@type": "Question",
"name": "Y a-t-il un lien entre l'IL-27 et l'alimentation ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines habitudes alimentaires peuvent influencer les niveaux d'IL-27, notamment les régimes riches en sucres."
}
}
]
}
]
}
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 18/02/2025
Contenu vérifié selon les dernières recommandations médicales
4 publications dans cette catégorie
Affiliations :
Department of Microbiology, Immunology, & Cell Biology, West Virginia University School of Medicine, Morgantown, WV, United States.
Vaccine Development Center, West Virginia University Health Sciences Center, Morgantown, WV, United States.
Publications dans "Interleukine-27" :
4 publications dans cette catégorie
Affiliations :
Laboratory of Human Retrovirology and Immunoinformatics, Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA.
Publications dans "Interleukine-27" :
3 publications dans cette catégorie
Affiliations :
Department of Microbiology, Immunology, & Cell Biology, West Virginia University School of Medicine, Morgantown, WV, United States.
Vaccine Development Center, West Virginia University Health Sciences Center, Morgantown, WV, United States.
Publications dans "Interleukine-27" :
3 publications dans cette catégorie
Affiliations :
Department of Microbiology, Immunology, & Cell Biology, West Virginia University School of Medicine, Morgantown, WV, United States.
Publications dans "Interleukine-27" :
3 publications dans cette catégorie
Affiliations :
Laboratory of Human Retrovirology and Immunoinformatics, Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA.
Publications dans "Interleukine-27" :
3 publications dans cette catégorie
Affiliations :
Laboratory of Human Retrovirology and Immunoinformatics, Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA.
Publications dans "Interleukine-27" :
3 publications dans cette catégorie
Affiliations :
Laboratory of Human Retrovirology and Immunoinformatics, Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA.
Publications dans "Interleukine-27" :
3 publications dans cette catégorie
Affiliations :
Laboratory of Human Retrovirology and Immunoinformatics, Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA.
Publications dans "Interleukine-27" :
3 publications dans cette catégorie
Affiliations :
Laboratory of Human Retrovirology and Immunoinformatics, Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA.
Publications dans "Interleukine-27" :
3 publications dans cette catégorie
Affiliations :
Laboratory of Human Retrovirology and Immunoinformatics, Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA.
Publications dans "Interleukine-27" :
3 publications dans cette catégorie
Affiliations :
Department of Microbiology, Immunology, & Cell Biology, West Virginia University School of Medicine, Morgantown, WV, USA.
Vaccine Development Center at West Virginia University Health Sciences Center, Morgantown, WV, USA.
Publications dans "Interleukine-27" :
3 publications dans cette catégorie
Affiliations :
Department of Microbiology, Immunology, & Cell Biology, West Virginia University School of Medicine, Morgantown, WV, USA.
Publications dans "Interleukine-27" :
2 publications dans cette catégorie
Affiliations :
Department of Immunology, School of Medicine, Kerman University of Medical Sciences, Kerman, Iran.
Immunology of Infectious Diseases Research Center, Research Institute of Basic Medical Sciences, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
Publications dans "Interleukine-27" :
2 publications dans cette catégorie
Affiliations :
Immunology of Infectious Diseases Research Center, Research Institute of Basic Medical Sciences, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
Department of Haematology and Laboratory Sciences, School of Para-Medicine, Kerman University of Medical Sciences, Kerman, Iran.
Publications dans "Interleukine-27" :
2 publications dans cette catégorie
Affiliations :
National Centre for Cell Science, Pune, India.
Publications dans "Interleukine-27" :
2 publications dans cette catégorie
Affiliations :
National Centre for Cell Science, Pune, India.
Trident Academy of Creative Technology, Bhubaneswar, India.
Publications dans "Interleukine-27" :
2 publications dans cette catégorie
Affiliations :
Department of Biomedical and Molecular Sciences, Queen's University, Kingston, ON, Canada.
Publications dans "Interleukine-27" :
2 publications dans cette catégorie
Affiliations :
Department of Biomedical and Molecular Sciences, Queen's University, Kingston, ON, Canada.
Publications dans "Interleukine-27" :
2 publications dans cette catégorie
Affiliations :
Department of Neurology, Tianjin Medical University General Hospital Airport Hospital, Tianjin, China.
Publications dans "Interleukine-27" :
2 publications dans cette catégorie
Affiliations :
Department of Neonatology, Ministry of Education Key Laboratory of Child Development and Disorders, National Clinical Research Center for Child Health and Disorders, Chongqing Key Laboratory of Pediatrics, Children's Hospital of Chongqing Medical University, Chongqing 400014, China.
Publications dans "Interleukine-27" :
The association between depression and sarcopenia has been reported in observational studies but the causality of depression on sarcopenia remained unknown. We aimed to assess the causal effect betwee...
A set of genetics instruments were used for analysis, derived from publicly available genetic summary data. Clinically, appendicular lean mass (ALM) and low hand grip strength (LHGS) have been widely ...
No evidence for an effect of MDD on sarcopenia risk was found. MDD was not associated with ALM [effect = -0.17 (-0.60 to 0.27), P = 0.449] and LHGS [effect = 0.24 (-0.46 to 0.93), P = 0.506]. Sarcopen...
MDD and Sarcopenia might mutually have no causal effect on each other....
A variety of factors, including diet and lifestyle, obesity, physiology, metabolism, hormone levels, psychology, and inflammation, have been associated with longevity. The specific influences of these...
A random effects model was used to investigate the association between 25 putative risk factors and longevity. The study population comprised 11,262 long-lived subjects (≥90 years old, including 3484 ...
Thirteen potential risk factors showed significant associations with longevity (≥90th) after correction for multiple testing. These included smoking initiation (OR:1.606; CI: 1.112-2.319) and educatio...
BMI was found to significantly affect longevity through SBP, plasma lipid (HDL/TC/LDL), and T2D. Future strategies should focus on modifying BMI to improve health and longevity....
Mendelian randomization borrows statistical techniques from economics to allow researchers to analyze the effects of the environment, drug treatments, and other factors on human biology and disease. T...
Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors represent an effective strategy for reducing cardiovascular disease risk. Yet, PCSK9's impact on osteoporosis remains unclear. Hence, w...
Single nucleotide polymorphisms (SNPs) for 3-hydroxy-3-methylglutaryl cofactor A reductase (HMGCR) and PCSK9 were gathered from available online databases for European pedigrees. Four osteoporosis-rel...
The meta-analysis involving a total of 1,263,102 subjects, showed that PCSK9 inhibitors can increase osteoporosis risk (P < 0.05, I...
PCSK9 inhibitors increase osteoporosis risk. However, HMGCR inhibitors are unremarkably linked to osteoporosis....
Confounding is a major limitation of observational studies. Mendelian randomization (MR) is a powerful study design that uses genetic variants as instrumental variables to enable examination of the ca...
Observational studies have reported an association between inflammatory bowel disease (IBD), which includes Crohn's disease (CD) and ulcerative colitis (UC), and hemorrhoids (HEM). However, the presen...
Colorectal cancer is the third most common and second most deadly type of cancer worldwide, with approximately 1.9 million cases and 0.9 million deaths worldwide in 2020. Previous studies have shown t...
Osteoarthritis (OA), a prevalent chronic disease among the elderly, presents a complex pathogenesis and currently lacks effective treatment. Traditional observational studies are time-consuming, labor...
There is no research to prove the association between irritability and lung cancer, our study performed a Mendelian randomization (MR) approach to elucidate the causal relationship of irritability wit...
Genome-wide association studies (GWAS) data of irritability, lung cancer and gastroesophageal reflux disease (GERD) were downloaded from a public database for two-sample MR analysis. Independent singl...
There is an association between irritability and lung cancer risk (OR...
This study confirmed the causal effect between irritability and lung cancer through MR analysis, and found that GERD played an essential mediating role in this relationship, which can partly indicate ...
Osteosarcoma (OS) is the primary bone tumor originating from transformed mesenchymal cells. It is unclear whether associations between specific circulating immune cells and OS are causal or due to bia...
The genetic variants strongly associated with immune cell traits as instrumental variables (IVs) were used to perform MR analyses. The effect of specific immune cells on OS risk was measured using the...
Our findings indicate that CD80 on CD62L+ myeloid dendritic cell and CD28-CD4-CD8- T-cell absolute count are positively associated with OS (CD80 on CD62L+ myeloid dendritic cell, OR: 3.41 [95% CI: 1.4...
These findings illustrate that the genetic predisposition to specific immune cells can exert a causal effect on OS risk, which confirms the crucial role played by immunity in OS development. Particula...