questionsmedicales.fr
Acides aminés, peptides et protéines
Protéines
Hémoprotéines
Cytochromes
Cytochrome P-450 enzyme system
Famille-2 de cytochromes P450
Limonène hydroxylases
Cytochrome P-450 CYP2C9
Cytochrome P-450 CYP2C9 : Questions médicales fréquentes
Termes MeSH sélectionnés :
Diagnostic
5
Tests génétiques
Polymorphisme génétique
Effets indésirables
Réponse au traitement
Interactions médicamenteuses
Profil métabolique
Métabolisme hépatique
Analyses sanguines
Symptômes
5
Nausées
Réactions allergiques
Surdose
Douleurs abdominales
Effets secondaires
Efficacité des médicaments
Carence enzymatique
Effets indésirables
Toxicité médicamenteuse
Éruptions cutanées
Prévention
5
Prévention
Suivi régulier
Anticoagulants
Saignement
Interactions médicamenteuses
Information médicale
Tests préventifs
Complications
Sensibilisation
Tests génétiques
Traitements
5
Ajustement de dose
Tests génétiques
Gestion des interactions
Surveillance thérapeutique
Traitements alternatifs
Médicaments
Surdose
Soins symptomatiques
Complications
5
Complications
Réactions allergiques
Surdose
Dommages organiques
Gestion des complications
Surveillance étroite
Déficience enzymatique
Maladies chroniques
Interactions médicamenteuses
Hospitalisations
Facteurs de risque
5
Facteurs de risque
Génétique
Alimentation
Inhibition enzymatique
Antifongiques
Inhibition enzymatique
Maladies hépatiques
Métabolisme des médicaments
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"acceptedAnswer": {
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{
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"name": "Comment prévenir les effets indésirables ?",
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}
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"name": "Comment ajuster les doses pour CYP2C9 ?",
"position": 16,
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{
"@type": "Question",
"name": "Quels médicaments sont métabolisés par CYP2C9 ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des médicaments comme la warfarine, le phénytoïne et certains AINS sont métabolisés par CYP2C9."
}
},
{
"@type": "Question",
"name": "Comment gérer les interactions médicamenteuses ?",
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"acceptedAnswer": {
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}
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{
"@type": "Question",
"name": "Quels traitements alternatifs pour les déficients ?",
"position": 19,
"acceptedAnswer": {
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"text": "Des alternatives médicamenteuses avec un métabolisme différent peuvent être envisagées."
}
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"@type": "Question",
"name": "Comment traiter une surdose liée à CYP2C9 ?",
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}
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"position": 21,
"acceptedAnswer": {
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}
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"@type": "Question",
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"acceptedAnswer": {
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"position": 23,
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"position": 24,
"acceptedAnswer": {
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"text": "Une déficience peut entraîner des effets à long terme sur la santé, comme des maladies chroniques."
}
},
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"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les interactions peuvent provoquer des complications comme des hospitalisations ou des traitements prolongés."
}
},
{
"@type": "Question",
"name": "Quels facteurs influencent CYP2C9 ?",
"position": 26,
"acceptedAnswer": {
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}
},
{
"@type": "Question",
"name": "Comment l'âge affecte CYP2C9 ?",
"position": 27,
"acceptedAnswer": {
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"text": "L'âge avancé peut réduire l'activité de CYP2C9, augmentant le risque d'effets indésirables."
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},
{
"@type": "Question",
"name": "Quel rôle de l'alimentation sur CYP2C9 ?",
"position": 28,
"acceptedAnswer": {
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"text": "Certaines substances alimentaires peuvent inhiber ou induire l'activité de CYP2C9."
}
},
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"name": "Quels médicaments augmentent le risque ?",
"position": 29,
"acceptedAnswer": {
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"text": "Des médicaments comme les antifongiques peuvent inhiber CYP2C9, augmentant le risque d'effets indésirables."
}
},
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"@type": "Question",
"name": "Comment les maladies hépatiques affectent CYP2C9 ?",
"position": 30,
"acceptedAnswer": {
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"text": "Les maladies hépatiques peuvent réduire l'activité de CYP2C9, affectant le métabolisme des médicaments."
}
}
]
}
]
}
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 29/03/2025
Contenu vérifié selon les dernières recommandations médicales
3 publications dans cette catégorie
Affiliations :
Department of Pharmacology, Faculty of Pharmacy, University of Pécs, Rókus u. 2, Pécs H-7624, Hungary; Lab-on-a-Chip Research Group, János Szentágothai Research Centre, University of Pécs, Ifjúság útja 20, Pécs H-7624, Hungary. Electronic address: poor.miklos@pte.hu.
Publications dans "Cytochrome P-450 CYP2C9" :
In vitro interaction of potential antiviral TMPRSS2 inhibitors with human serum albumin and cytochrome P 450 isoenzymes.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
2021-12-13
Interaction of myricetin, ampelopsin (dihydromyricetin), and their sulfate metabolites with serum albumin, cytochrome P450 (CYP2C9, 2C19, and 3A4) enzymes, and organic anion-transporting polypeptides (OATP1B1 and OATP2B1).
Pharmacology research & perspectives
Interaction of luteolin, naringenin, and their sulfate and glucuronide conjugates with human serum albumin, cytochrome P450 (CYP2C9, CYP2C19, and CYP3A4) enzymes and organic anion transporting polypeptide (OATP1B1 and OATP2B1) transporters.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
2022-12-05
3 publications dans cette catégorie
Affiliations :
The Key laboratory of Geriatrics, Beijing Institute of Geriatrics, Beijing Hospital, National Center of Gerontology, National Health Commission, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, P. R. China.
Publications dans "Cytochrome P-450 CYP2C9" :
2 publications dans cette catégorie
Affiliations :
Department of Pharmacology, Faculty of Pharmacy, University of Pécs, Rókus u. 2, Pécs H-7624, Hungary; Lab-on-a-Chip Research Group, János Szentágothai Research Centre, University of Pécs, Ifjúság útja 20, Pécs H-7624, Hungary.
Publications dans "Cytochrome P-450 CYP2C9" :
2 publications dans cette catégorie
Affiliations :
Department of Pharmacology, Faculty of Pharmacy, University of Pécs, Rókus u. 2, Pécs H-7624, Hungary; Lab-on-a-Chip Research Group, János Szentágothai Research Centre, University of Pécs, Ifjúság útja 20, Pécs H-7624, Hungary.
Publications dans "Cytochrome P-450 CYP2C9" :
2 publications dans cette catégorie
Affiliations :
The Key laboratory of Geriatrics, Beijing Institute of Geriatrics, Beijing Hospital, National Center of Gerontology, National Health Commission, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, P. R. China.
Publications dans "Cytochrome P-450 CYP2C9" :
2 publications dans cette catégorie
Affiliations :
Cardiovascular Department, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, P. R. China.
Publications dans "Cytochrome P-450 CYP2C9" :
2 publications dans cette catégorie
Affiliations :
Laboratory of Clinical Pharmacy, The Sixth Affiliated Hospital of Wenzhou Medical University, The People's Hospital of Lishui, Lishui, P.R. China.
Publications dans "Cytochrome P-450 CYP2C9" :
2 publications dans cette catégorie
Affiliations :
Laboratory of Clinical Pharmacy, The Sixth Affiliated Hospital of Wenzhou Medical University, The People's Hospital of Lishui, Lishui, P.R. China.
Publications dans "Cytochrome P-450 CYP2C9" :
2 publications dans cette catégorie
Affiliations :
Laboratory of Clinical Pharmacy, The Sixth Affiliated Hospital of Wenzhou Medical University, The People's Hospital of Lishui, Lishui, P.R. China.
Publications dans "Cytochrome P-450 CYP2C9" :
2 publications dans cette catégorie
Affiliations :
Cardiovascular Department, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, P. R. China.
Publications dans "Cytochrome P-450 CYP2C9" :
2 publications dans cette catégorie
Affiliations :
Cardiovascular Department, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, P. R. China.
Publications dans "Cytochrome P-450 CYP2C9" :
2 publications dans cette catégorie
Affiliations :
The Key laboratory of Geriatrics, Beijing Institute of Geriatrics, Beijing Hospital, National Center of Gerontology, National Health Commission, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, P. R. China.
Publications dans "Cytochrome P-450 CYP2C9" :
2 publications dans cette catégorie
Affiliations :
Department of Pharmacotherapy and Translational Research, Center for Pharmacogenomics and Precision Medicine, University of Florida, Gainesville, Florida, USA.
Publications dans "Cytochrome P-450 CYP2C9" :
2 publications dans cette catégorie
Affiliations :
Federal University of Sao Joao del-Rei, Av. Sebastiao Goncalves Coelho, 400, Campus Centro-Oeste, Chanadour, Divinopolis-MG, CEP: 35501-296, Brazil.
Federal University of Minas Gerais, Av. Presidente Antonio Carlos, 667, Campus Pampulha, Belo Horizonte-MG, CEP: 31270-901, Brazil.
Publications dans "Cytochrome P-450 CYP2C9" :
2 publications dans cette catégorie
Affiliations :
Federal University of Sao Joao del-Rei, Av. Sebastiao Goncalves Coelho, 400, Campus Centro-Oeste, Chanadour, Divinopolis-MG, CEP: 35501-296, Brazil.
Publications dans "Cytochrome P-450 CYP2C9" :
2 publications dans cette catégorie
Affiliations :
Federal University of Sao Joao del-Rei, Av. Sebastiao Goncalves Coelho, 400, Campus Centro-Oeste, Chanadour, Divinopolis-MG, CEP: 35501-296, Brazil.
Publications dans "Cytochrome P-450 CYP2C9" :
2 publications dans cette catégorie
Affiliations :
Federal University of Sao Joao del-Rei, Av. Sebastiao Goncalves Coelho, 400, Campus Centro-Oeste, Chanadour, Divinopolis-MG, CEP: 35501-296, Brazil.
Publications dans "Cytochrome P-450 CYP2C9" :
2 publications dans cette catégorie
Affiliations :
Drug Resistance Research Group, Institute of Molecular Life Sciences, Research Centre for Natural Sciences, HUN-REN, Budapest, Hungary.
Doctoral School of Biology, Institute of Biology, Eötvös Loránd University, Budapest, Hungary.
Publications dans "Cytochrome P-450 CYP2C9" :
2 publications dans cette catégorie
Affiliations :
Institute of Microbiology of the Czech Academy of Sciences, Prague, Czech Republic.
Publications dans "Cytochrome P-450 CYP2C9" :
2 publications dans cette catégorie
Affiliations :
Drug Resistance Research Group, Institute of Molecular Life Sciences, Research Centre for Natural Sciences, HUN-REN, Budapest, Hungary.
Publications dans "Cytochrome P-450 CYP2C9" :
Glioblastoma is the most common form of primary brain cancer in adults, and the disease has a serious prognosis. Although great progress has been made in molecular characteristics, no major breakthrou...
Epilepsy is a common medical condition that affects people of all ages, races, social classes, and geographical regions. Diagnosis of epilepsy remains clinical, and ancillary investigations (electroen...
This paper will discuss the management of adult patients with cleft lip and palate who return to care, often many decades after their initial course of treatment. This can be a very complex group of p...
Taking another person's perspective provides a means to infer their beliefs and intentions (known as Theory of Mind), which is an essential part of social interaction. In this article, we examined how...
Human interaction is immersed in laughter; though genuine and posed laughter are acoustically distinct, they are both crucial socio-emotional signals. In this novel study, autistic and non-autistic ad...
Increases in e-cigarette use are of concern to public health authorities given the harms associated with vaping. Understanding people's perceptions of the risks and benefits of e-cigarette use has the...
Idiopathic hypogonadotropic hypogonadism (IHH) occurs mostly in childhood or adolescence and very rarely in adulthood. It is characterised by delayed onset of secondary sexual characteristics. Many ge...
Vasculitis is characterized by the inflammation of blood vessels. Vasculitides refers to the different forms of vasculitis, often classified according to the size of the blood vessel that is involved....
Faecal incontinence, which is defined by the unintentional loss of solid or liquid stool, has a worldwide prevalence of ≤7% in community-dwelling adults and can markedly impair quality of life. Noneth...
Neutrophils are an important component of the innate immune system, and they prevent bacterial and fungal infections by phagocytosis and killing of pathogens. Neutropenia is defined as an abnormally l...