Engineered GH11 xylanases from Orpinomyces sp. PC-2 improve techno-functional properties of bread dough.


Journal

Journal of the science of food and agriculture
ISSN: 1097-0010
Titre abrégé: J Sci Food Agric
Pays: England
ID NLM: 0376334

Informations de publication

Date de publication:
30 Jan 2019
Historique:
received: 03 05 2018
revised: 22 06 2018
accepted: 06 07 2018
pubmed: 13 7 2018
medline: 12 1 2019
entrez: 13 7 2018
Statut: ppublish

Résumé

Endo-1,4-β-xylanases have marked hydrolytic activity towards arabinoxylans. Xylanases (xynA) produced by the anaerobic fungus Orpinomyces sp. strain PC-2 have been shown to be superior in specific activity, which strongly suggests their applicability in the bakery industry for the processing of whole-wheat flour containing xylans. In the present study, two xylanases from this source, the small wild-type xylanase SWT and the small mutant xylanase SM2 (V108A, A199T), were expressed in Escherichia coli, purified, characterized, tested for their ability to hydrolyze whole-wheat flour and applied in dough processing. Both purified SM2 and SWT showed high specific activity against oat spelt xylan and wheat arabinoxylan, exhibiting maximum activity at pH 3-7 and 60 °C. SM2 was more thermostable than SWT, which suggests that the mutations enhanced its stability. Both SWT and SM2 were able to hydrolyze whole-wheat flour, and evaluation of their applicability in dough processing by the sponge method indicated that use of these enzymes increased dough volume by 60% and reduced texture hardness by more than 50%, while gumminess and chewiness were reduced by 40%. The recombinant xylanases showed potential for application in bakery processing and can improve techno-functional properties in sponges. © 2018 Society of Chemical Industry.

Sections du résumé

BACKGROUND BACKGROUND
Endo-1,4-β-xylanases have marked hydrolytic activity towards arabinoxylans. Xylanases (xynA) produced by the anaerobic fungus Orpinomyces sp. strain PC-2 have been shown to be superior in specific activity, which strongly suggests their applicability in the bakery industry for the processing of whole-wheat flour containing xylans. In the present study, two xylanases from this source, the small wild-type xylanase SWT and the small mutant xylanase SM2 (V108A, A199T), were expressed in Escherichia coli, purified, characterized, tested for their ability to hydrolyze whole-wheat flour and applied in dough processing.
RESULTS RESULTS
Both purified SM2 and SWT showed high specific activity against oat spelt xylan and wheat arabinoxylan, exhibiting maximum activity at pH 3-7 and 60 °C. SM2 was more thermostable than SWT, which suggests that the mutations enhanced its stability. Both SWT and SM2 were able to hydrolyze whole-wheat flour, and evaluation of their applicability in dough processing by the sponge method indicated that use of these enzymes increased dough volume by 60% and reduced texture hardness by more than 50%, while gumminess and chewiness were reduced by 40%.
CONCLUSION CONCLUSIONS
The recombinant xylanases showed potential for application in bakery processing and can improve techno-functional properties in sponges. © 2018 Society of Chemical Industry.

Identifiants

pubmed: 29999533
doi: 10.1002/jsfa.9242
doi:

Substances chimiques

Fungal Proteins 0
Xylans 0
arabinoxylan 9040-27-1
Endo-1,4-beta Xylanases EC 3.2.1.8

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

741-747

Subventions

Organisme : Fundação de Amparo à Pesquisa do Estado de Minas Gerais (FAPEMIG)
Organisme : Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
Organisme : Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Informations de copyright

© 2018 Society of Chemical Industry.

Auteurs

Amanda Tafuri Paniago Passarinho (ATP)

Nucleus of Research in Biological Sciences, Federal University of Ouro Preto, Ouro Preto, Brazil.

Rafaela Zandonade Ventorim (RZ)

Department of Biochemistry and Molecular Biology, Federal University of Viçosa, Viçosa, Brazil.

Gabriela Piccolo Maitan-Alfenas (GP)

Department of Food and Nutrition, Federal University of Mato Grosso, Cuiabá, Brazil.

Eduardo Basílio de Oliveira (EB)

Department of Food Technology, Federal University of Viçosa, Viçosa, Brazil.

Valéria Monteze Guimarães (VM)

Department of Biochemistry and Molecular Biology, Federal University of Viçosa, Viçosa, Brazil.

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Classifications MeSH