MapOptics: a light-weight, cross-platform visualization tool for optical mapping alignment.


Journal

Bioinformatics (Oxford, England)
ISSN: 1367-4811
Titre abrégé: Bioinformatics
Pays: England
ID NLM: 9808944

Informations de publication

Date de publication:
01 08 2019
Historique:
received: 16 09 2018
revised: 27 11 2018
accepted: 06 12 2018
pubmed: 12 12 2018
medline: 17 6 2020
entrez: 12 12 2018
Statut: ppublish

Résumé

Bionano optical mapping is a technology that can assist in the final stages of genome assembly by lengthening and ordering scaffolds in a draft assembly by aligning the assembly to a genomic map. However, currently, tools for visualization are limited to use on a Windows operating system or are developed initially for visualizing large-scale structural variation. MapOptics is a lightweight cross-platform tool that enables the user to visualize and interact with the alignment of Bionano optical mapping data and can be used for in depth exploration of hybrid scaffolding alignments. It provides a fast, simple alternative to the large optical mapping analysis programs currently available for this area of research. MapOptics is implemented in Java 1.8 and released under an MIT licence. MapOptics can be downloaded from https://github.com/FadyMohareb/mapoptics and run on any standard desktop computer equipped with a Java Virtual Machine (JVM). Supplementary data are available at Bioinformatics online.

Identifiants

pubmed: 30535283
pii: 5232997
doi: 10.1093/bioinformatics/bty1013
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

2671-2673

Subventions

Organisme : Biotechnology and Biological Sciences Research Council
ID : BB/L011611/1
Pays : United Kingdom

Informations de copyright

© The Author(s) 2018. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Auteurs

Josephine Burgin (J)

The Bioinformatics Group, Cranfield Soil and Agrifood Institute, School of Water, Energy and Environment, Cranfield University, Bedford MK43 0AL, UK.

Corentin Molitor (C)

The Bioinformatics Group, Cranfield Soil and Agrifood Institute, School of Water, Energy and Environment, Cranfield University, Bedford MK43 0AL, UK.

Fady Mohareb (F)

The Bioinformatics Group, Cranfield Soil and Agrifood Institute, School of Water, Energy and Environment, Cranfield University, Bedford MK43 0AL, UK.

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Classifications MeSH