Generation of Level- k LGT Networks.


Journal

IEEE/ACM transactions on computational biology and bioinformatics
ISSN: 1557-9964
Titre abrégé: IEEE/ACM Trans Comput Biol Bioinform
Pays: United States
ID NLM: 101196755

Informations de publication

Date de publication:
Historique:
pubmed: 1 2 2019
medline: 5 1 2021
entrez: 1 2 2019
Statut: ppublish

Résumé

Phylogenetic networks provide a mathematical model to represent the evolution of a set of species where, apart from speciation, reticulate evolutionary events have to be taken into account. Among these events, lateral gene transfers need special consideration due to the asymmetry in the roles of the species involved in such an event. To take into account this asymmetry, LGT networks were introduced. Contrarily to the case of phylogenetic trees, the combinatorial structure of phylogenetic networks is much less known and difficult to describe. One of the approaches in the literature is to classify them according to their level and find generators of the given level that can be used to recursively generate all networks. In this paper, we adapt the concept of generators to the case of LGT networks. We show how these generators, classified by their level, give rise to simple LGT networks of the specified level, and how any LGT network can be obtained from these simple networks, that act as building blocks of the generic structure. The stochastic models of evolution of phylogenetic networks are also much less studied than those for phylogenetic trees. In this setting, we introduce a novel two-parameter model that generates LGT networks. Finally, we present some computer simulations using this model in order to investigate the complexity of the generated networks, depending on the parameters of the model.

Identifiants

pubmed: 30703035
doi: 10.1109/TCBB.2019.2895344
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

158-164

Auteurs

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Classifications MeSH