Tetrahymena Comparative Genomics Database (TCGD): a community resource for Tetrahymena.

Databases, Genetic Genome, Protozoan Genomics Macronucleus / genetics Synteny / genetics Tetrahymena / genetics

Journal

Database : the journal of biological databases and curation
ISSN: 1758-0463
Titre abrégé: Database (Oxford)
Pays: England
ID NLM: 101517697

Informations de publication

Date de publication:
01 01 2019
Historique:
received: 14 11 2018
revised: 04 02 2019
accepted: 06 02 2019
entrez: 28 2 2019
pubmed: 28 2 2019
medline: 25 7 2019
Statut: ppublish

Résumé

Ciliates are a large and diverse group of unicellular organisms characterized by having the following two distinct type of nuclei within a single cell: micronucleus (MIC) and macronucleus (MAC). Although the genomes of several ciliates in different groups have been sequenced, comparative genomics data for multiple species within a ciliate genus are not yet available. Here we collected the genome information and comparative genomics analysis results for 10 species in the Tetrahymena genus, including the previously sequenced model organism Tetrahymena thermophila and 9 newly sequenced species, and constructed a genus-level comparative analysis platform, the Tetrahymena Comparative Genomics Database (TCGD). Genome sequences, transcriptomic data, gene models, functional annotation, ortholog groups and synteny maps were built into this database and a user-friendly interface was developed for searching, visualizing and analyzing these data. In summary, the TCGD (http://ciliate.ihb.ac.cn) will be an important and useful resource for the ciliate research community.

Identifiants

DOI: 10.1093/database/baz029 PMID: 30810209 PMC: PMC6391650
pubmed: 30810209
pii: 5365189
doi: 10.1093/database/baz029
pmc: PMC6391650
pii:
doi:

Types de publication

Comparative Study Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Informations de copyright

© The Author(s) 2019. Published by Oxford University Press.

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Auteurs

Wentao Yang (W)

Key Laboratory of Aquatic Biodiversity and Conservation, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.
University of Chinese Academy of Sciences, Beijing, China.

Chuanqi Jiang (C)

Key Laboratory of Aquatic Biodiversity and Conservation, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.
University of Chinese Academy of Sciences, Beijing, China.

Ying Zhu (Y)

Nextomics Biosciences Institute, Wuhan, China.

Kai Chen (K)

Key Laboratory of Aquatic Biodiversity and Conservation, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.
University of Chinese Academy of Sciences, Beijing, China.

Guangying Wang (G)

Key Laboratory of Aquatic Biodiversity and Conservation, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.
University of Chinese Academy of Sciences, Beijing, China.

Dongxia Yuan (D)

Key Laboratory of Aquatic Biodiversity and Conservation, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.

Wei Miao (W)

Key Laboratory of Aquatic Biodiversity and Conservation, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.
University of Chinese Academy of Sciences, Beijing, China.
State Key Laboratory of Freshwater Ecology and Biotechnology, Wuhan, China.
CAS Center for Excellence in Animal Evolution and Genetics, Kunming, China.

Jie Xiong (J)

Key Laboratory of Aquatic Biodiversity and Conservation, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.

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Classifications MeSH

questionsmedicales.fr › Sciences de l'information › Mémorisation et recherche des informations › Bases de données comme sujet › Bases de données factuelles › Bases de données génétiques › Tetrahymena Comparative Genomics Database...
questionsmedicales.fr › Phénomènes génétiques › Structures génétiques › Génome › Génome de protozoaire › Tetrahymena Comparative Genomics Database...
questionsmedicales.fr › Disciplines des sciences naturelles › Disciplines des sciences biologiques › Biologie › Génétique › Génomique › Tetrahymena Comparative Genomics Database...
questionsmedicales.fr › Cellules › Structures cellulaires › Espace intracellulaire › Cytoplasme › Structures cytoplasmiques › Organites › Noyau de la cellule › Macronucléus › Tetrahymena Comparative Genomics Database...
questionsmedicales.fr › Phénomènes génétiques › Similitude de séquences › Similitude de séquences d'acides nucléiques › Synténie › Tetrahymena Comparative Genomics Database...
questionsmedicales.fr › Eucaryotes › Alveolata › Ciliophora › Oligohymenophorea › Hymenostomatida › Tetrahymenina › Tetrahymena › Tetrahymena Comparative Genomics Database...