Longitudinal advanced MRI case report of white matter radiation necrosis.

Radiation necrosis mostly occurs in and near the radiation field. We used magnetic resonance imaging to study radiation-induced necrosis of atypical onset, severity, and extent following stereotactic radiosurgery for a symptomatic arteriovenous malformation. Susceptibility-sensitive imaging, T

Déclaration de conflit d'intérêts

Vanessa Wiggermann has nothing to disclose. Emmanuelle Lapointe has received consulting fees from Roche, Biogen, and EMD Serono and speaker fees from Genzyme and EMD Serono. Ludmila Litvin, Carina Graf, and Enedino Hernández‐Torres report no disclosures. Michael McKenzie is on the Steering Committee for a randomized trial in prostate cancer sponsored by Janssen R&D. He has received honoraria from Abbott, Bayer, Amgen, and Ferring as well as from Varian. Irene M Vavasour and Cornelia Laule have no disclosures. Erin L. Macmillan is supported by Philips Healthcare Canada. David Li has received research funding from the Canadian Institute of Health Research and Multiple Sclerosis Society of Canada. He is the Emeritus Director of the UBC MS/MRI Research Group, which has been contracted to perform central analysis of MRI scans for therapeutic trials with Novartis, Perceptives, Roche, and Sanofi‐Aventis. The UBC MS/MRI Research Group has also received grant support for investigator‐initiated independent studies from Genzyme, Merck‐Serono, Novartis, and Roche. He has acted as a consultant to Vertex Pharmaceuticals and served on the Data and Safety Advisory Board for Opexa Therapeutics and Scientific Advisory Boards for Adelphi Group, Celgene, Novartis, and Roche. He has also given lectures which have been supported by nonrestricted education grants from Biogen‐Idec, Novartis, Sanofi‐Genzyme, and Teva. Shannon Kolind has consulted for Acorda and Genzyme. She has received research support from Roche. She is grateful for support from the MS Society of Canada and the Milan & Maureen Ilich Foundation. Alexander Rauscher has received funding from NSERC and the National MS Society as well as speaker fees from Philips Medical. Anthony Traboulsee has received grant funding from the MS Society of Canada, Canadian Institute for Health Research, Roche, and Genzyme; he also received honoraria or travel grants from Teva Canada Innovation, Roche, Merck/EMD Serono, Genzyme, Chugai Pharmaceuticals.