Genome plasticity in

Candida albicans antifungal drug resistance chromosomes gene expression genetics genome instability genomics inverted repeats loss of heterozygosity segmental aneuploidy

Journal

eLife
ISSN: 2050-084X
Titre abrégé: Elife
Pays: England
ID NLM: 101579614

Informations de publication

Date de publication:
07 06 2019
Historique:
received: 10 02 2019
accepted: 07 06 2019
pubmed: 8 6 2019
medline: 23 2 2020
entrez: 8 6 2019
Statut: epublish

Résumé

Genome rearrangements resulting in copy number variation (CNV) and loss of heterozygosity (LOH) are frequently observed during the somatic evolution of cancer and promote rapid adaptation of fungi to novel environments. In the human fungal pathogen

Identifiants

pubmed: 31172944
doi: 10.7554/eLife.45954
pii: 45954
pmc: PMC6591007
doi:
pii:

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Nebraska LB692 New Initiatives Grants
ID : LB692 NE Tobacco Settlement Biomedical Research Development New Initiative Grant
Pays : International
Organisme : Creighton University
ID : CURAS Faculty Faculty Research Fund
Pays : International
Organisme : NIH HHS
ID : R15 AI090633
Pays : United States
Organisme : NCRR NIH HHS
ID : P20RR018788 sub award
Pays : United States
Organisme : Nebraska Established Program to Stimulate Competitive Research
ID : EPSCoR First Award
Pays : International
Organisme : NCRR NIH HHS
ID : P20 RR018788
Pays : United States
Organisme : NIAID NIH HHS
ID : R15 AI090633
Pays : United States
Organisme : Nebraska Department of Health and Human Services
ID : LB506-2017-55
Pays : International
Organisme : Nebraska's Established Program to Stimulate Competitive Research
ID : EPSCoR First Award
Pays : International

Informations de copyright

© 2019, Todd et al.

Déclaration de conflit d'intérêts

RT, TW, AF, AS No competing interests declared

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Auteurs

Robert T Todd (RT)

Creighton University Medical School, Omaha, United States.

Tyler D Wikoff (TD)

Creighton University Medical School, Omaha, United States.

Anja Forche (A)

Bowdoin College, Brunswick, United States.

Anna Selmecki (A)

Creighton University Medical School, Omaha, United States.

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Classifications MeSH