Adenocarcinoma of Lung
/ drug therapy
Animals
CRISPR-Cas Systems
/ genetics
Cell Cycle Proteins
/ genetics
Cell Differentiation
/ drug effects
Cell Line, Tumor
Disease Models, Animal
Drug Resistance, Neoplasm
/ genetics
Epigenesis, Genetic
/ immunology
Gene Expression Regulation, Neoplastic
/ immunology
Gene Knockout Techniques
HEK293 Cells
Humans
Immune Checkpoint Inhibitors
/ pharmacology
Lung
/ pathology
Lung Neoplasms
/ drug therapy
Macrophages
/ drug effects
Male
Mice
Molecular Chaperones
/ genetics
Programmed Cell Death 1 Receptor
/ antagonists & inhibitors
Proto-Oncogene Proteins p21(ras)
/ genetics
RNA, Guide, Kinetoplastida
/ genetics
RNA, Small Interfering
/ metabolism
RNA-Seq
Tumor Microenvironment
/ drug effects
Tumor Suppressor Protein p53
/ genetics
Journal
Cancer discovery
ISSN: 2159-8290
Titre abrégé: Cancer Discov
Pays: United States
ID NLM: 101561693
Informations de publication
Date de publication:
02 2020
02 2020
Historique:
received:
03
07
2019
revised:
11
10
2019
accepted:
13
11
2019
pubmed:
21
11
2019
medline:
30
1
2021
entrez:
21
11
2019
Statut:
ppublish
Résumé
Despite substantial progress in lung cancer immunotherapy, the overall response rate in patients with
Identifiants
pubmed: 31744829
pii: 2159-8290.CD-19-0780
doi: 10.1158/2159-8290.CD-19-0780
pmc: PMC7007372
mid: NIHMS1544097
doi:
Substances chimiques
ASF1A protein, human
0
Asf1a protein, mouse
0
Cell Cycle Proteins
0
Immune Checkpoint Inhibitors
0
KRAS protein, human
0
Molecular Chaperones
0
Pdcd1 protein, mouse
0
Programmed Cell Death 1 Receptor
0
RNA, Guide
0
RNA, Small Interfering
0
Trp53 protein, mouse
0
Tumor Suppressor Protein p53
0
Hras protein, mouse
EC 3.6.5.2
Proto-Oncogene Proteins p21(ras)
EC 3.6.5.2
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
270-287Subventions
Organisme : NCI NIH HHS
ID : R01 CA216188
Pays : United States
Organisme : NCI NIH HHS
ID : P50 CA101942
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA219670
Pays : United States
Organisme : NCI NIH HHS
ID : U01 CA233084
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA166480
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA222218
Pays : United States
Commentaires et corrections
Type : CommentIn
Informations de copyright
©2019 American Association for Cancer Research.
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