Quantitative Framework for Model Evaluation in Microbiology Research Using


Journal

mBio
ISSN: 2150-7511
Titre abrégé: mBio
Pays: United States
ID NLM: 101519231

Informations de publication

Date de publication:
14 01 2020
Historique:
entrez: 16 1 2020
pubmed: 16 1 2020
medline: 18 9 2020
Statut: epublish

Résumé

Laboratory models are a cornerstone of modern microbiology, but the accuracy of these models has not been systematically evaluated. As a result, researchers often choose models based on intuition or incomplete data. We propose a general quantitative framework to assess model accuracy from RNA sequencing data and use this framework to evaluate models of

Identifiants

pubmed: 31937646
pii: mBio.03042-19
doi: 10.1128/mBio.03042-19
pmc: PMC6960289
pii:
doi:

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : NHLBI NIH HHS
ID : R56 HL142857
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL123771
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL142587
Pays : United States
Organisme : NIGMS NIH HHS
ID : R01 GM116547
Pays : United States
Organisme : NHLBI NIH HHS
ID : R33 HL137077
Pays : United States

Informations de copyright

Copyright © 2020 Cornforth et al.

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Auteurs

Daniel M Cornforth (DM)

School of Biological Sciences, Georgia Institute of Technology, Center for Microbial Dynamics and Infection, Georgia Institute of Technology, Atlanta, Georgia, USA dcornforth@gmail.com mwhiteley3@gatech.edu.
Emory-Children's Cystic Fibrosis Center, Atlanta, Georgia, USA.

Frances L Diggle (FL)

School of Biological Sciences, Georgia Institute of Technology, Center for Microbial Dynamics and Infection, Georgia Institute of Technology, Atlanta, Georgia, USA.
Emory-Children's Cystic Fibrosis Center, Atlanta, Georgia, USA.

Jeffrey A Melvin (JA)

Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.

Jennifer M Bomberger (JM)

Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.

Marvin Whiteley (M)

School of Biological Sciences, Georgia Institute of Technology, Center for Microbial Dynamics and Infection, Georgia Institute of Technology, Atlanta, Georgia, USA dcornforth@gmail.com mwhiteley3@gatech.edu.
Emory-Children's Cystic Fibrosis Center, Atlanta, Georgia, USA.

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Classifications MeSH