Transcriptome-wide-scale-predicted dsRNAs potentially involved in RNA homoeostasis are remarkably excluded from genes with no/very low expression in all developmental stages.

Animals Argonaute Proteins / metabolism Computational Biology / methods Drosophila Proteins / genetics Drosophila melanogaster / genetics Exons Gene Expression Profiling Gene Expression Regulation, Developmental Introns RNA Helicases / metabolism RNA, Double-Stranded / metabolism RNA, Long Noncoding / genetics RNA, Messenger / genetics Ribonuclease III / metabolism Exome Sequencing
Ago2 Computational dsRNA Dicer2 endo-siRNAs epigenetics mRNA homoeostasis

Journal

RNA biology
ISSN: 1555-8584
Titre abrégé: RNA Biol
Pays: United States
ID NLM: 101235328

Informations de publication

Date de publication:
04 2020
Historique:
pubmed: 24 1 2020
medline: 27 4 2021
entrez: 24 1 2020
Statut: ppublish

Résumé

RNA interference (RNAi) refers to a conserved posttranscriptional mechanism for the degradation of RNA by short dsRNAs. A genome-wide analysis of mRNAs that are complementary to RNAs of variable length that are transcribed from the full transcriptome and susceptible to being loaded onto

Identifiants

DOI: 10.1080/15476286.2020.1717154 PMID: 31971862 PMC: PMC7237139
pubmed: 31971862
doi: 10.1080/15476286.2020.1717154
pmc: PMC7237139
doi:

Substances chimiques

AGO2 protein, Drosophila 0
Argonaute Proteins 0
Drosophila Proteins 0
RNA, Double-Stranded 0
RNA, Long Noncoding 0
RNA, Messenger 0
DCR-2 protein, Drosophila EC 2.7.7.-
Ribonuclease III EC 3.1.26.3
RNA Helicases EC 3.6.4.13

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

554-570

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Auteurs

Claude Pasquier (C)

Laboratoire d'informatique, signaux et système (I3S) CNRS, Université Côte d'Azur, Sophia Antipolis, France.

Sandra Agnel (S)

Agrobiotech Institute (ISA)INRA, CNRS, Université Côte d'Azur, Sophia Antipolis, France.

Alain Robichon (A)

Agrobiotech Institute (ISA)INRA, CNRS, Université Côte d'Azur, Sophia Antipolis, France.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Transcriptome-wide-scale-predicted dsRNAs...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Nucléoprotéines › Protéines de liaison à l'ARN › Ribonucléoprotéines › Complexe réprimant l'expression de l'ARN › Protéines Argonaute › Transcriptome-wide-scale-predicted dsRNAs...
questionsmedicales.fr › Sciences de l'information › Informatique › Biologie informatique › Transcriptome-wide-scale-predicted dsRNAs...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines d'arthropode › Protéines d'insecte › Protéines de Drosophila › Transcriptome-wide-scale-predicted dsRNAs...
questionsmedicales.fr › Eucaryotes › Animaux › Invertébrés › Arthropodes › Insectes › Pterygota › Neoptera › Holometabola › Diptera › Drosophilidae › Drosophila › Drosophila melanogaster › Transcriptome-wide-scale-predicted dsRNAs...
questionsmedicales.fr › Phénomènes génétiques › Structures génétiques › Génome › Composants de génome › Gènes › Composants de gène › Exons › Transcriptome-wide-scale-predicted dsRNAs...
questionsmedicales.fr › Techniques d'investigation › Techniques génétiques › Analyse de profil d'expression de gènes › Transcriptome-wide-scale-predicted dsRNAs...
questionsmedicales.fr › Phénomènes génétiques › Régulation de l'expression des gènes › Régulation de l'expression des gènes au cours du développement › Transcriptome-wide-scale-predicted dsRNAs...
questionsmedicales.fr › Phénomènes génétiques › Structures génétiques › Génome › Composants de génome › Gènes › Composants de gène › Introns › Transcriptome-wide-scale-predicted dsRNAs...
questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Transferases › Phosphotransferases › Nucleotidyltransferases › RNA nucleotidyltransferases › RNA helicases › Transcriptome-wide-scale-predicted dsRNAs...
questionsmedicales.fr › Phénomènes génétiques › Structures génétiques › Conformation d'acide nucléique › ARN double brin › Transcriptome-wide-scale-predicted dsRNAs...
questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Acides nucléiques › ARN › ARN non traduit › ARN long non codant › Transcriptome-wide-scale-predicted dsRNAs...
questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Acides nucléiques › ARN › ARN messager › Transcriptome-wide-scale-predicted dsRNAs...
questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Hydrolases › Esterases › Ribonucléases › Endoribonucleases › Ribonuclease III › Transcriptome-wide-scale-predicted dsRNAs...
questionsmedicales.fr › Techniques d'investigation › Techniques génétiques › Analyse de séquence › Analyse de séquence d'ADN › Séquençage du génome entier › Séquençage de l'exome › Transcriptome-wide-scale-predicted dsRNAs...