Intra-strain biological and epidemiological characterization of plum pox virus.
evolutionary epidemiology
intra-strain variation
plum pox virus
positive selection
reversible evolution
transient attenuation
Journal
Molecular plant pathology
ISSN: 1364-3703
Titre abrégé: Mol Plant Pathol
Pays: England
ID NLM: 100954969
Informations de publication
Date de publication:
04 2020
04 2020
Historique:
received:
19
08
2019
revised:
12
12
2019
accepted:
14
12
2019
pubmed:
25
1
2020
medline:
26
1
2021
entrez:
25
1
2020
Statut:
ppublish
Résumé
Plum pox virus (PPV) is one of the most important plant viruses causing serious economic losses. Thus far, strain typing based on the definition of 10 monophyletic strains with partially differentiable biological properties has been the sole approach used for epidemiological characterization of PPV. However, elucidating the genetic determinants underlying intra-strain biological variation among populations or isolates remains a relevant but unexamined aspect of the epidemiology of the virus. In this study, based on complete nucleotide sequence information of 210 Japanese and 47 non-Japanese isolates of the PPV-Dideron (D) strain, we identified five positively selected sites in the PPV-D genome. Among them, molecular studies showed that amino acid substitutions at position 2,635 in viral replicase correlate with viral titre and competitiveness at the systemic level, suggesting that amino acid position 2,635 is involved in aphid transmission efficiency and symptom severity. Estimation of ancestral genome sequences indicated that substitutions at amino acid position 2,635 were reversible and peculiar to one of two genetically distinct PPV-D populations in Japan. The reversible amino acid evolution probably contributes to the dissemination of the virus population. This study provides the first genomic insight into the evolutionary epidemiology of PPV based on intra-strain biological variation ascribed to positive selection.
Identifiants
pubmed: 31978272
doi: 10.1111/mpp.12908
pmc: PMC7060144
doi:
Substances chimiques
Viral Proteins
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
475-488Informations de copyright
© 2020 The Authors. Molecular Plant Pathology published by British Society for Plant Pathology and John Wiley & Sons Ltd.
Références
Proc Natl Acad Sci U S A. 2001 Nov 20;98(24):13757-62
pubmed: 11717435
Bioinformatics. 2000 Jun;16(6):562-3
pubmed: 10980155
Mol Plant Pathol. 2008 Mar;9(2):251-68
pubmed: 18705856
J Gen Virol. 2019 Oct;100(10):1457-1468
pubmed: 31418674
J Exp Med. 2004 Dec 20;200(12):1593-604
pubmed: 15611288
J Gen Virol. 2004 Sep;85(Pt 9):2671-2681
pubmed: 15302961
AIDS Res Hum Retroviruses. 1995 Nov;11(11):1423-5
pubmed: 8573403
Annu Rev Phytopathol. 2015;53:357-78
pubmed: 26047559
Virus Res. 2009 May;141(2):258-67
pubmed: 19195488
Mol Plant Pathol. 2011 Dec;12(9):938-54
pubmed: 22017770
Bioinformatics. 2000 Jul;16(7):573-82
pubmed: 11038328
Mol Plant Pathol. 2020 Apr;21(4):475-488
pubmed: 31978272
Mol Plant Microbe Interact. 2010 Mar;23(3):283-93
pubmed: 20121450
Phytopathology. 2000 Oct;90(10):1068-72
pubmed: 18944468
Phytopathology. 2011 May;101(5):567-74
pubmed: 21198358
Phytopathology. 2014 Jul;104(7):794-9
pubmed: 24915431
J Gen Virol. 1998 Apr;79 ( Pt 4):897-904
pubmed: 9568986
Virology. 1999 Dec 20;265(2):218-25
pubmed: 10600594
Mol Plant Microbe Interact. 2008 Jan;21(1):20-9
pubmed: 18052879
Arch Virol. 2002 Mar;147(3):563-75
pubmed: 11958455
Phytopathology. 2013 May;103(5):509-12
pubmed: 23301813
Virus Evol. 2015 May 26;1(1):vev003
pubmed: 27774277
Mol Biol Evol. 2005 May;22(5):1208-22
pubmed: 15703242
PLoS Pathog. 2009 Jan;5(1):e1000254
pubmed: 19119418
Mol Plant Microbe Interact. 2013 Oct;26(10):1211-24
pubmed: 23745677
Proc Natl Acad Sci U S A. 1995 Jan 17;92(2):457-61
pubmed: 7831310
Mol Biol Rep. 2006 Sep;33(3):215-21
pubmed: 16850191
Nat Med. 2004 Mar;10(3):282-9
pubmed: 14770175
Genetics. 2007 Jun;176(2):1035-47
pubmed: 17409078
Plant Dis. 2012 Sep;96(9):1331-1336
pubmed: 30727156
Annu Rev Phytopathol. 2017 Aug 4;55:139-160
pubmed: 28525307
Mol Biol Evol. 2013 Dec;30(12):2725-9
pubmed: 24132122
Mol Biol Evol. 2018 Mar 1;35(3):773-777
pubmed: 29301006
Mol Plant Pathol. 2014 Apr;15(3):226-41
pubmed: 24102673
Mol Biol Evol. 2013 May;30(5):1196-205
pubmed: 23420840
Annu Rev Phytopathol. 1998;36:415-37
pubmed: 15012507
Phytopathology. 2011 May;101(5):627-36
pubmed: 21261466
Arch Virol. 2016 Feb;161(2):425-30
pubmed: 26530833
Phytopathology. 2015 Nov;105(11):1408-16
pubmed: 26512749
Phytopathology. 2001 Feb;91(2):159-64
pubmed: 18944389
Phytopathology. 2013 Sep;103(9):972-9
pubmed: 23581702
BMC Plant Biol. 2012 Jul 08;12:103
pubmed: 22770370
Virology. 1996 Dec 1;226(1):146-51
pubmed: 8941334
Proc Natl Acad Sci U S A. 1991 Sep 1;88(17):7887-91
pubmed: 1881922
Virus Res. 2006 Mar;116(1-2):214-7
pubmed: 16406166
Annu Rev Phytopathol. 2006;44:183-212
pubmed: 16602948
Bioinformatics. 2005 Mar 1;21(5):676-9
pubmed: 15509596
Phytopathology. 2011 May;101(5):611-9
pubmed: 21171886
Mol Biol Evol. 1997 Nov;14(11):1125-31
pubmed: 9364770
Virology. 1966 Dec;30(4):631-7
pubmed: 5928794
J Mol Evol. 1992 Feb;34(2):126-9
pubmed: 1556748
Adv Virus Res. 2006;67:355-418
pubmed: 17027685
Plant Dis. 2018 Mar;102(3):569-575
pubmed: 30673474