Ligand-induced conformational changes in a SMALP-encapsulated GPCR.

Hydrophobic and Hydrophilic Interactions Ligands Lipids / chemistry Maleates / chemistry Pichia / chemistry Protein Conformation Receptor, Adenosine A2A / chemistry Spectrometry, Fluorescence / methods Styrene / chemistry Triazines / pharmacology Triazoles / pharmacology Tryptophan / chemistry
Adenosine receptor Fluorescence GPCR SMALP

Journal

Biochimica et biophysica acta. Biomembranes
ISSN: 1879-2642
Titre abrégé: Biochim Biophys Acta Biomembr
Pays: Netherlands
ID NLM: 101731713

Informations de publication

Date de publication:
01 06 2020
Historique:
received: 04 10 2019
revised: 25 02 2020
accepted: 26 02 2020
pubmed: 4 3 2020
medline: 21 8 2020
entrez: 4 3 2020
Statut: ppublish

Résumé

The adenosine 2A receptor (A

Identifiants

DOI: 10.1016/j.bbamem.2020.183235 PMID: 32126232 PMC: PMC7156913
pubmed: 32126232
pii: S0005-2736(20)30060-2
doi: 10.1016/j.bbamem.2020.183235
pmc: PMC7156913
pii:
doi:

Substances chimiques

Ligands 0
Lipids 0
Maleates 0
Receptor, Adenosine A2A 0
Triazines 0
Triazoles 0
ZM 241385 0
Styrene 44LJ2U959V
Tryptophan 8DUH1N11BX
maleic acid 91XW058U2C

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

183235

Subventions

Organisme : Biotechnology and Biological Sciences Research Council
ID : BB/I020349/1
Pays : United Kingdom
Organisme : Biotechnology and Biological Sciences Research Council
ID : BB/I019960/1
Pays : United Kingdom
Organisme : Biotechnology and Biological Sciences Research Council
ID : BB/R016615/1
Pays : United Kingdom
Organisme : Biotechnology and Biological Sciences Research Council
ID : BB/R016755/1
Pays : United Kingdom

Informations de copyright

Copyright © 2020 The Authors. Published by Elsevier B.V. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Références

Nanoscale. 2015 Dec 28;7(48):20685-96
pubmed: 26599076
Nature. 2018 Mar 1;555(7694):121-125
pubmed: 29466332
Biochim Biophys Acta. 2012 Sep;1818(9):2228-33
pubmed: 22551944
Nature. 2018 Jul;559(7714):423-427
pubmed: 29995853
J Am Chem Soc. 2009 Jun 10;131(22):7484-5
pubmed: 19449872
Biochim Biophys Acta. 2015 Nov;1848(11 Pt A):2889-97
pubmed: 26275588
Nucleic Acids Res. 2018 Jan 4;46(D1):D440-D446
pubmed: 29155946
Mol Pharmacol. 2013 May;83(5):949-58
pubmed: 23429888
Br J Pharmacol. 2013 Jul;169(5):988-98
pubmed: 23489072
Life Sci. 2005 Feb 11;76(13):1513-26
pubmed: 15680315
Pharmacol Rev. 2011 Mar;63(1):1-34
pubmed: 21303899
Annu Rev Pharmacol Toxicol. 2020 Jan 6;60:89-107
pubmed: 31454292
Nature. 2012 Jan 29;482(7384):237-40
pubmed: 22286059
Nature. 2018 Sep;561(7724):492-497
pubmed: 30209400
Nanoscale. 2018 Jun 7;10(22):10609-10619
pubmed: 29845165
Nano Res. 2015 Mar;8(3):774-789
pubmed: 31031888
Curr Protoc Bioinformatics. 2016 Jun 20;54:5.6.1-5.6.37
pubmed: 27322406
Biochim Biophys Acta Biomembr. 2020 May 1;1862(5):183192
pubmed: 31945320
Nat Commun. 2018 Apr 10;9(1):1372
pubmed: 29636462
J Biol Chem. 2002 Oct 25;277(43):40989-96
pubmed: 12167654
Science. 2012 Jul 13;337(6091):232-6
pubmed: 22798613
Langmuir. 2016 Nov 15;32(45):11845-11853
pubmed: 27739678
Angew Chem Int Ed Engl. 2015 Jan 7;54(2):556-9
pubmed: 25403323
Nature. 2011 Jul 19;477(7366):549-55
pubmed: 21772288
Science. 2008 Nov 21;322(5905):1211-7
pubmed: 18832607
Nature. 2016 Aug 4;536(7614):104-7
pubmed: 27462812
Nature. 2016 Aug 25;536(7617):484-7
pubmed: 27525504
Annu Rev Pharmacol Toxicol. 2005;45:385-412
pubmed: 15822182
Protein Expr Purif. 2010 Nov;74(1):80-7
pubmed: 20438843
Proc Natl Acad Sci U S A. 2018 Apr 24;115(17):4501-4506
pubmed: 29632174
Nat Protoc. 2016 Jul;11(7):1149-62
pubmed: 27254461
Nat Rev Drug Discov. 2002 Feb;1(2):103-10
pubmed: 12120091
Nature. 2011 May 18;474(7352):521-5
pubmed: 21593763
Biochem Soc Trans. 2016 Apr 15;44(2):619-23
pubmed: 27068979
Br J Pharmacol. 2012 Mar;165(6):1688-1703
pubmed: 21864311
Nat Rev Drug Discov. 2019 Jan;18(1):59-82
pubmed: 30410121
Biosci Rep. 2015 Apr 16;35(2):
pubmed: 25720391
J Biol Chem. 2010 Apr 23;285(17):13032-44
pubmed: 20147292
Nat Rev Drug Discov. 2017 Dec;16(12):829-842
pubmed: 29075003
Protein Sci. 2014 Jan;23(1):47-55
pubmed: 24265211
Sci Rep. 2018 Oct 8;8(1):14950
pubmed: 30297885
Structure. 2011 Sep 7;19(9):1283-93
pubmed: 21885291
Biochem J. 2001 Apr 15;355(Pt 2):449-57
pubmed: 11284733
Biochemistry. 1996 Aug 27;35(34):11149-59
pubmed: 8780519
Nat Chem Biol. 2016 Jan;12(1):35-9
pubmed: 26571351
Nat Chem Biol. 2006 Aug;2(8):417-22
pubmed: 16799554
Biochemistry. 2016 Jan 12;55(1):38-48
pubmed: 26701065
Annu Rev Biochem. 2010;79:737-75
pubmed: 20307193
Nat Rev Mol Cell Biol. 2018 Oct;19(10):638-653
pubmed: 30104700
Biochem J. 2011 Aug 1;437(3):541-53
pubmed: 21561435

Auteurs

Sarah J Routledge (SJ)

Life and Health Sciences, Aston University, Birmingham B4 7ET, UK.

Mohammed Jamshad (M)

School of Biosciences, University of Birmingham, Birmingham B15 2TT, UK.

Haydn A Little (HA)

School of Biosciences, University of Birmingham, Birmingham B15 2TT, UK.

Yu-Pin Lin (YP)

School of Biosciences, University of Birmingham, Birmingham B15 2TT, UK.

John Simms (J)

Life and Health Sciences, Aston University, Birmingham B4 7ET, UK.

Alpesh Thakker (A)

Life and Health Sciences, Aston University, Birmingham B4 7ET, UK.

Corinne M Spickett (CM)

Life and Health Sciences, Aston University, Birmingham B4 7ET, UK.

Roslyn M Bill (RM)

Life and Health Sciences, Aston University, Birmingham B4 7ET, UK.

Tim R Dafforn (TR)

School of Biosciences, University of Birmingham, Birmingham B15 2TT, UK. Electronic address: t.r.dafforn@bham.ac.uk.

David R Poyner (DR)

Life and Health Sciences, Aston University, Birmingham B4 7ET, UK. Electronic address: d.r.poyner@aston.ac.uk.

Mark Wheatley (M)

Centre for Sport, Exercise and Life Sciences, Alison Gingell Building, Faculty of Health and Life Sciences, Coventry University, Coventry CV1 2DS, UK; Centre of Membrane Proteins and Receptors (COMPARE), University of Birmingham and University of Nottingham, Midlands, UK. Electronic address: mark.wheatley@coventry.ac.uk.

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Classifications MeSH

questionsmedicales.fr › Phénomènes chimiques › Interactions hydrophobes et hydrophiles › Ligand-induced conformational changes in a...
questionsmedicales.fr › Actions chimiques et utilisations › Utilisations spécialisées de produits chimiques › Produits chimiques de laboratoire › Ligands › Ligand-induced conformational changes in a...
questionsmedicales.fr › Lipides › Ligand-induced conformational changes in a...
questionsmedicales.fr › Composés chimiques organiques › Acides carboxyliques › Acides acycliques › Diacides carboxyliques › Maléates › Ligand-induced conformational changes in a...
questionsmedicales.fr › Eucaryotes › Champignons › Levures › Pichia › Ligand-induced conformational changes in a...
questionsmedicales.fr › Phénomènes chimiques › Phénomènes biochimiques › Conformation moléculaire › Conformation des protéines › Ligand-induced conformational changes in a...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs aux neuromédiateurs › Récepteurs purinergiques › Récepteurs purinergiques P1 › Récepteurs A2 à l'adénosine › Récepteur A2A à l'adénosine › Ligand-induced conformational changes in a...
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Analyse spectrale › Spectrométrie de fluorescence › Ligand-induced conformational changes in a...
questionsmedicales.fr › Composés chimiques organiques › Hydrocarbures › Hydrocarbures cycliques › Hydrocarbures aromatiques › Dérivés du benzène › Composés benzylidéniques › Styrènes › Styrène › Ligand-induced conformational changes in a...
questionsmedicales.fr › Composés hétérocycliques › Composés hétéromonocycliques › Triazines › Ligand-induced conformational changes in a...
questionsmedicales.fr › Composés hétérocycliques › Composés hétéromonocycliques › Azoles › Triazoles › Ligand-induced conformational changes in a...
questionsmedicales.fr › Acides aminés, peptides et protéines › Acides aminés › Acides aminés essentiels › Tryptophane › Ligand-induced conformational changes in a...