Six new dimeric 2-(2-phenylethyl)chromones from artificial agarwood of Aquilaria sinensis.

Cholinesterase Inhibitors / isolation & purification Flavonoids / chemistry Glycoside Hydrolase Inhibitors / chemistry Thymelaeaceae / chemistry Wood / chemistry
Aquilaria sinensis Artificial agarwood Dimeric 2-(2-phenylethyl)chromone

Journal

Fitoterapia
ISSN: 1873-6971
Titre abrégé: Fitoterapia
Pays: Netherlands
ID NLM: 16930290R

Informations de publication

Date de publication:
Apr 2020
Historique:
received: 04 02 2020
revised: 03 03 2020
accepted: 03 03 2020
pubmed: 10 3 2020
medline: 19 12 2020
entrez: 10 3 2020
Statut: ppublish

Résumé

Six new dimeric 2-(2-phenylethyl)chromones (1-6) were isolated from the EtOAc extract of artificial agarwood originating from Aquilaria sinensis (Lour.) Glig. Their structures were unambiguously elucidated by spectroscopic techniques (UV, IR, 1D and 2D NMR), and HRESIMS analysis, as well as by comparison with the literature. The absolute configurations were determined by ECD spectra.

Identifiants

DOI: 10.1016/j.fitote.2020.104542 PMID: 32147491
pubmed: 32147491
pii: S0367-326X(20)30124-6
doi: 10.1016/j.fitote.2020.104542
pii:
doi:

Substances chimiques

Cholinesterase Inhibitors 0
Flavonoids 0
Glycoside Hydrolase Inhibitors 0
2-(2-phenylethyl)chromone 61828-53-3

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

104542

Informations de copyright

Copyright © 2020 Elsevier B.V. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Competing Interest There are no conflicts of interest to declare.

Auteurs

Pan Xiang (P)

Hainan Engineering Research Center of Agarwood, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, PR China; Hainan Key laboratory for research and development of natural products from Li folk medicine, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, PR China.

Huiqin Chen (H)

Hainan Engineering Research Center of Agarwood, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, PR China; Hainan Key laboratory for research and development of natural products from Li folk medicine, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, PR China.

Caihong Cai (C)

Hainan Engineering Research Center of Agarwood, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, PR China; Hainan Key laboratory for research and development of natural products from Li folk medicine, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, PR China.

Hao Wang (H)

Hainan Engineering Research Center of Agarwood, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, PR China; Hainan Key laboratory for research and development of natural products from Li folk medicine, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, PR China.

Liman Zhou (L)

Hainan Engineering Research Center of Agarwood, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, PR China; Hainan Key laboratory for research and development of natural products from Li folk medicine, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, PR China.

Wenli Mei (W)

Hainan Engineering Research Center of Agarwood, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, PR China; Hainan Key laboratory for research and development of natural products from Li folk medicine, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, PR China. Electronic address: meiwenli@itbb.org.cn.

Haofu Dai (H)

Hainan Engineering Research Center of Agarwood, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, PR China; Hainan Key laboratory for research and development of natural products from Li folk medicine, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, PR China. Electronic address: daihaofu@itbb.org.cn.

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Classifications MeSH

questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Effets physiologiques des médicaments › Agents neuromédiateurs › Agents cholinergiques › Anticholinestérasiques › Six new dimeric 2-(2-phenylethyl)chromones...
questionsmedicales.fr › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérobicycliques › Benzopyranes › 4H-1-Benzopyran-4-ones › Flavonoïdes › Six new dimeric 2-(2-phenylethyl)chromones...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Effets physiologiques des médicaments › Hypoglycémiants › Inhibiteurs des glycoside hydrolases › Six new dimeric 2-(2-phenylethyl)chromones...
questionsmedicales.fr › Eucaryotes › Viridiplantae › Streptophyta › Embryophyta › Tracheobionta › Magnoliopsida › Thymelaeaceae › Six new dimeric 2-(2-phenylethyl)chromones...
questionsmedicales.fr › Technologie, industrie et agriculture › Produits manufacturés › Matériaux de construction › Bois › Six new dimeric 2-(2-phenylethyl)chromones...