An algal enzyme required for biosynthesis of the most abundant marine carotenoids.
Journal
Science advances
ISSN: 2375-2548
Titre abrégé: Sci Adv
Pays: United States
ID NLM: 101653440
Informations de publication
Date de publication:
03 2020
03 2020
Historique:
received:
05
02
2019
accepted:
11
12
2019
entrez:
18
3
2020
pubmed:
18
3
2020
medline:
13
11
2020
Statut:
epublish
Résumé
Fucoxanthin and its derivatives are the main light-harvesting pigments in the photosynthetic apparatus of many chromalveolate algae and represent the most abundant carotenoids in the world's oceans, thus being major facilitators of marine primary production. A central step in fucoxanthin biosynthesis that has been elusive so far is the conversion of violaxanthin to neoxanthin. Here, we show that in chromalveolates, this reaction is catalyzed by violaxanthin de-epoxidase-like (VDL) proteins and that VDL is also involved in the formation of other light-harvesting carotenoids such as peridinin or vaucheriaxanthin. VDL is closely related to the photoprotective enzyme violaxanthin de-epoxidase that operates in plants and most algae, revealing that in major phyla of marine algae, an ancient gene duplication triggered the evolution of carotenoid functions beyond photoprotection toward light harvesting.
Identifiants
pubmed: 32181334
doi: 10.1126/sciadv.aaw9183
pii: aaw9183
pmc: PMC7056318
doi:
Substances chimiques
Algal Proteins
0
Light-Harvesting Protein Complexes
0
Xanthophylls
0
fucoxanthin
06O0TC0VSM
peridinin
33281-81-1
Carotenoids
36-88-4
violaxanthin
51C926029A
Oxidoreductases
EC 1.-
violaxanthin de-epoxidase
EC 1.-
neoxanthin
KK8M5T48AI
Chlorophyll A
YF5Q9EJC8Y
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.
Langues
eng
Sous-ensembles de citation
IM
Pagination
eaaw9183Subventions
Organisme : Howard Hughes Medical Institute
Pays : United States
Informations de copyright
Copyright © 2020 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution License 4.0 (CC BY).
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