Dopamine D2 receptors in discrimination learning and spine enlargement.
Animals
Calcium
/ metabolism
Calcium-Calmodulin-Dependent Protein Kinase Type 2
/ metabolism
Conditioning, Classical
/ drug effects
Dendritic Spines
/ drug effects
Discrimination Learning
/ drug effects
Dopamine
/ metabolism
Dopamine D2 Receptor Antagonists
/ pharmacology
Extinction, Psychological
/ drug effects
Male
Methamphetamine
/ antagonists & inhibitors
Mice
Neuronal Plasticity
Neurons
/ drug effects
Nucleus Accumbens
/ drug effects
Optogenetics
Receptor, Adenosine A2A
/ metabolism
Receptors, Dopamine D1
/ metabolism
Receptors, Dopamine D2
/ metabolism
Reward
Signal Transduction
/ drug effects
Synapses
/ metabolism
Journal
Nature
ISSN: 1476-4687
Titre abrégé: Nature
Pays: England
ID NLM: 0410462
Informations de publication
Date de publication:
03 2020
03 2020
Historique:
received:
21
06
2019
accepted:
17
01
2020
entrez:
28
3
2020
pubmed:
28
3
2020
medline:
2
6
2020
Statut:
ppublish
Résumé
Dopamine D2 receptors (D2Rs) are densely expressed in the striatum and have been linked to neuropsychiatric disorders such as schizophrenia
Identifiants
pubmed: 32214250
doi: 10.1038/s41586-020-2115-1
pii: 10.1038/s41586-020-2115-1
doi:
Substances chimiques
Dopamine D2 Receptor Antagonists
0
Receptor, Adenosine A2A
0
Receptors, Dopamine D1
0
Receptors, Dopamine D2
0
Methamphetamine
44RAL3456C
Calcium-Calmodulin-Dependent Protein Kinase Type 2
EC 2.7.11.17
Calcium
SY7Q814VUP
Dopamine
VTD58H1Z2X
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
555-560Références
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