Guide to Immunopharmacology: a database to boost immunology education, research and therapy.


Journal

Immunology
ISSN: 1365-2567
Titre abrégé: Immunology
Pays: England
ID NLM: 0374672

Informations de publication

Date de publication:
05 2020
Historique:
entrez: 17 4 2020
pubmed: 17 4 2020
medline: 20 11 2020
Statut: ppublish

Résumé

In the era of big data, the establishment of a free database, containing all the immune drug targets and associated cell types, is of great value. To this aim, the Guide to Immunopharmacology has been created in a joint effort between the International Union of Basic and Clinical Pharmacology (IUPHAR) and the International Union of Immunological Societies (IUIS). Here we highlight the structure and content of the database, which includes up-to-date quantitative information on the fundamental science underlying each immune target. A set of practical examples and tools for data mining are summarized to support immune research into drug discovery and therapeutics.

Identifiants

pubmed: 32297319
doi: 10.1111/imm.13201
pmc: PMC7160655
doi:

Substances chimiques

Immunologic Factors 0

Types de publication

Editorial Introductory Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1-2

Informations de copyright

© 2020 John Wiley & Sons Ltd.

Références

Immunology. 2020 Mar;159(3):257-278
pubmed: 31782148
Clin Exp Immunol. 2010 Mar;159(3):268-80
pubmed: 19968662
Cardiovasc Res. 2019 Jan 1;115(1):e5-e6
pubmed: 30576437
Nucleic Acids Res. 2018 Jan 4;46(D1):D1091-D1106
pubmed: 29149325
Immunology. 2020 Feb;159(2):167-177
pubmed: 31646612
Immunology. 2020 May;160(1):10-23
pubmed: 32020584
Nat Rev Immunol. 2018 Dec;18(12):729
pubmed: 30327546
Curr Protoc Bioinformatics. 2018 Mar;61(1):1.34.1-1.34.46
pubmed: 30040201
Nucleic Acids Res. 2020 Jan 8;48(D1):D1006-D1021
pubmed: 31691834
Br J Pharmacol. 2015 Sep;172(17):4217-27
pubmed: 26173913
Clin Exp Immunol. 2015 Mar;179(3):529-38
pubmed: 25354724
Clin Exp Immunol. 1995 Nov;102(2):281-5
pubmed: 7586679
Clin Exp Immunol. 2005 Aug;141(2):191-200
pubmed: 15996182
Br J Pharmacol. 2017 Jul;174(13):1875-1880
pubmed: 28299772
Clin Exp Immunol. 2018 Dec;194(3):295-314
pubmed: 30144037
Clin Exp Immunol. 2008 Jul;153(1):117-26
pubmed: 18505432

Auteurs

Simon Milling (S)

Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.

Michael Spedding (M)

Spedding Research Solutions SAS, Le Vésinet, France.

Pasquale Maffia (P)

Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.
Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.
Department of Pharmacy, University of Naples Federico II, Naples, Italy.

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Classifications MeSH