Reversible and site-specific immobilization of β
Aptamer
Drug-protein interaction
G-protein coupled receptor
Site-specific immobilization
Journal
Journal of chromatography. A
ISSN: 1873-3778
Titre abrégé: J Chromatogr A
Pays: Netherlands
ID NLM: 9318488
Informations de publication
Date de publication:
05 Jul 2020
05 Jul 2020
Historique:
received:
25
11
2019
revised:
23
03
2020
accepted:
29
03
2020
pubmed:
8
5
2020
medline:
25
7
2020
entrez:
8
5
2020
Statut:
ppublish
Résumé
Immobilized protein makes a profound impact on the development of assays for drug discovery, diagnosis and in vivo biological interaction analysis. Traditional methods are enormously challenged by the G-protein coupled receptor ascribed to the loss of receptor functions. We introduced a β
Identifiants
pubmed: 32376022
pii: S0021-9673(20)30312-5
doi: 10.1016/j.chroma.2020.461091
pii:
doi:
Substances chimiques
Adrenergic beta-Agonists
0
Ligands
0
Receptors, Adrenergic, beta-2
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
461091Informations de copyright
Copyright © 2020 Elsevier B.V. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest The authors declare that they have no known competingfinancial interestsor personal relationships that could have appeared to influence the work reported in this paper.