Small-Angle Scattering and Multifractal Analysis of DNA Sequences.
DNA sequences
multifractals
multiplicative cascades
small-angle scattering
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
30 Jun 2020
30 Jun 2020
Historique:
received:
06
06
2020
revised:
28
06
2020
accepted:
28
06
2020
entrez:
8
7
2020
pubmed:
8
7
2020
medline:
17
2
2021
Statut:
epublish
Résumé
The arrangement of A, C, G and T nucleotides in large DNA sequences of many prokaryotic and eukaryotic cells exhibit long-range correlations with fractal properties. Chaos game representation (CGR) of such DNA sequences, followed by a multifractal analysis, is a useful way to analyze the corresponding scaling properties. This approach provides a powerful visualization method to characterize their spatial inhomogeneity, and allows discrimination between mono- and multifractal distributions. However, in some cases, two different arbitrary point distributions, may generate indistinguishable multifractal spectra. By using a new model based on multiplicative deterministic cascades, here it is shown that small-angle scattering (SAS) formalism can be used to address such issue, and to extract additional structural information. It is shown that the box-counting dimension given by multifractal spectra can be recovered from the scattering exponent of SAS intensity in the fractal region. This approach is illustrated for point distributions of CGR data corresponding to
Identifiants
pubmed: 32629908
pii: ijms21134651
doi: 10.3390/ijms21134651
pmc: PMC7369734
pii:
doi:
Substances chimiques
DNA
9007-49-2
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
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