Europium-Diethylenetriaminepentaacetic Acid Loaded Radioluminescence Liposome Nanoplatform for Effective Radioisotope-Mediated Photodynamic Therapy.

Europium Liposomes Luminescence Pentetic Acid Photochemotherapy Radioisotopes
europium photodynamic therapy positron emission tomography radioluminescence therapeutic

Journal

ACS nano
ISSN: 1936-086X
Titre abrégé: ACS Nano
Pays: United States
ID NLM: 101313589

Informations de publication

Date de publication:
27 10 2020
Historique:
pubmed: 22 8 2020
medline: 15 5 2021
entrez: 22 8 2020
Statut: ppublish

Résumé

Photodynamic therapy (PDT) is an effective anticancer strategy with a higher selectivity and fewer adverse effects than conventional therapies; however, shallow tissue penetration depth of light has hampered the clinical utility of PDT. Recently, reports have indicated that Cerenkov luminescence-induced PDT may overcome the tissue penetration limitation of conventional PDT. However, the effectiveness of this method is controversial because of its low luminescence intensity. Herein, we developed a radiolabeled diethylenetriaminepentaacetic acid chelated Eu

Identifiants

DOI: 10.1021/acsnano.0c04324 PMID: 32820903
pubmed: 32820903
doi: 10.1021/acsnano.0c04324
doi:

Substances chimiques

Liposomes 0
Radioisotopes 0
Europium 444W947O8O
Pentetic Acid 7A314HQM0I

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

13004-13015

Auteurs

Wooseung Lee (W)

Department of Applied Bioengineering, Graduate School of Convergence Science and Technology, Seoul National University, Seoul 08826, Republic of Korea.

Miyeon Jeon (M)

Department of Applied Bioengineering, Graduate School of Convergence Science and Technology, Seoul National University, Seoul 08826, Republic of Korea.

Jinyeong Choi (J)

Department of Applied Bioengineering, Graduate School of Convergence Science and Technology, Seoul National University, Seoul 08826, Republic of Korea.

Chiwoo Oh (C)

Department of Applied Bioengineering, Graduate School of Convergence Science and Technology, Seoul National University, Seoul 08826, Republic of Korea.

Gaeun Kim (G)

Department of Applied Bioengineering, Graduate School of Convergence Science and Technology, Seoul National University, Seoul 08826, Republic of Korea.

Seongmoon Jung (S)

Department of Applied Bioengineering, Graduate School of Convergence Science and Technology, Seoul National University, Seoul 08826, Republic of Korea.
Department of Radiation Oncology, Seoul National University Hospital, Seoul 03080, Republic of Korea.

Changsoon Kim (C)

Department of Intelligence and Information, Graduate School of Convergence Science and Technology, Seoul National University, Seoul 08826, Republic of Korea.
Inter-University Semiconductor Research Center, Seoul National University, Seoul 08826, Republic of Korea.
ORCID: 0000-0002-3825-6293

Sung-Joon Ye (SJ)

Department of Applied Bioengineering, Graduate School of Convergence Science and Technology, Seoul National University, Seoul 08826, Republic of Korea.
ORCID: 0000-0001-8714-6317

Hyung-Jun Im (HJ)

Department of Applied Bioengineering, Graduate School of Convergence Science and Technology, Seoul National University, Seoul 08826, Republic of Korea.
Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul 08826, Republic of Korea.
ORCID: 0000-0002-4368-6685

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Classifications MeSH

questionsmedicales.fr › Produits chimiques inorganiques › Métaux › Terres rares › Lanthanides › Europium › Europium-Diethylenetriaminepentaacetic Acid...
questionsmedicales.fr › Technologie, industrie et agriculture › Produits manufacturés › Matériaux biomimétiques › Membrane artificielle › Liposomes › Europium-Diethylenetriaminepentaacetic Acid...
questionsmedicales.fr › Phénomènes physiques › Rayonnement › Rayonnement non ionisant › Lumière › Luminescence › Europium-Diethylenetriaminepentaacetic Acid...
questionsmedicales.fr › Composés chimiques organiques › Acides carboxyliques › Acides acycliques › Acide pentétique › Europium-Diethylenetriaminepentaacetic Acid...
questionsmedicales.fr › Thérapeutique › Photothérapie › Photothérapie dynamique › Europium-Diethylenetriaminepentaacetic Acid...
questionsmedicales.fr › Produits chimiques inorganiques › Isotopes › Radio-isotopes › Europium-Diethylenetriaminepentaacetic Acid...