Binding Modes and Selectivity of Cannabinoid 1 (CB1) and Cannabinoid 2 (CB2) Receptor Ligands.

Cannabinoid Receptor Agonists Cannabinoids Ligands Molecular Docking Simulation Protein Binding Receptor, Cannabinoid, CB1 Receptor, Cannabinoid, CB2
Cannabinoid receptor drug design strategy endocannabinoid modeling selectivity

Journal

ACS chemical neuroscience
ISSN: 1948-7193
Titre abrégé: ACS Chem Neurosci
Pays: United States
ID NLM: 101525337

Informations de publication

Date de publication:
21 10 2020
Historique:
pubmed: 1 10 2020
medline: 22 6 2021
entrez: 30 9 2020
Statut: ppublish

Résumé

The cannabinoid (CB) receptors (CB

Identifiants

DOI: 10.1021/acschemneuro.0c00551 PMID: 32997485 PMC: PMC7756905
pubmed: 32997485
doi: 10.1021/acschemneuro.0c00551
pmc: PMC7756905
mid: NIHMS1652169
doi:

Substances chimiques

Cannabinoid Receptor Agonists 0
Cannabinoids 0
Ligands 0
Receptor, Cannabinoid, CB1 0
Receptor, Cannabinoid, CB2 0

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, U.S. Gov't, Non-P.H.S.

Langues

eng

Sous-ensembles de citation

IM

Pagination

3455-3463

Subventions

Organisme : NIGMS NIH HHS
ID : P20 GM130456
Pays : United States
Organisme : NIDA NIH HHS
ID : R01 DA039143
Pays : United States
Organisme : NIDA NIH HHS
ID : T32 DA016176
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR001998
Pays : United States

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Auteurs

Jing-Fang Yang (JF)

Alexander H Williams (AH)

Narsimha R Penthala (NR)

Department of Pharmaceutical Sciences, College of Pharmacy, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, United States.

Paul L Prather (PL)

Department of Pharmacology and Toxicology, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, United States.

Peter A Crooks (PA)

Department of Pharmaceutical Sciences, College of Pharmacy, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, United States.

Chang-Guo Zhan (CG)

ORCID: 0000-0002-4128-7269

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Classifications MeSH

questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Effets physiologiques des médicaments › Hormones, substituts d'hormones et antagonistes d'hormones › Hormones › Modulateurs des récepteurs de cannabinoïdes › Agonistes des récepteurs de cannabinoïdes › Binding Modes and Selectivity of Cannabinoid 1...
questionsmedicales.fr › Composés chimiques organiques › Hydrocarbures › Terpènes › Cannabinoïdes › Binding Modes and Selectivity of Cannabinoid 1...
questionsmedicales.fr › Actions chimiques et utilisations › Utilisations spécialisées de produits chimiques › Produits chimiques de laboratoire › Ligands › Binding Modes and Selectivity of Cannabinoid 1...
questionsmedicales.fr › Sciences de l'information › Méthodologies informatiques › Simulation numérique › Simulation de docking moléculaire › Binding Modes and Selectivity of Cannabinoid 1...
questionsmedicales.fr › Métabolisme › Liaison aux protéines › Binding Modes and Selectivity of Cannabinoid 1...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs couplés aux protéines G › Récepteurs de cannabinoïdes › Récepteur cannabinoïde de type CB1 › Binding Modes and Selectivity of Cannabinoid 1...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs couplés aux protéines G › Récepteurs de cannabinoïdes › Récepteur cannabinoïde de type CB2 › Binding Modes and Selectivity of Cannabinoid 1...