Plant TDP1 (Tyrosyl-DNA Phosphodiesterase 1): A Phylogenetic Perspective and Gene Expression Data Mining.


Journal

Genes
ISSN: 2073-4425
Titre abrégé: Genes (Basel)
Pays: Switzerland
ID NLM: 101551097

Informations de publication

Date de publication:
07 12 2020
Historique:
received: 30 10 2020
revised: 02 12 2020
accepted: 03 12 2020
entrez: 10 12 2020
pubmed: 11 12 2020
medline: 22 7 2021
Statut: epublish

Résumé

The TDP1 (tyrosyl-DNA phosphodiesterase 1) enzyme removes the non-specific covalent intermediates between topoisomerase I and DNA, thus playing a crucial role in preventing DNA damage. While mammals possess only one

Identifiants

pubmed: 33297410
pii: genes11121465
doi: 10.3390/genes11121465
pmc: PMC7762302
pii:
doi:

Substances chimiques

Plant Proteins 0
Phosphoric Diester Hydrolases EC 3.1.4.-
tyrosyl-DNA phosphodiesterase EC 3.1.4.-

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

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Auteurs

Giacomo Mutti (G)

Department of Biology and Biotechnology 'L. Spallanzani', University of Pavia, via Ferrata 9, 27100 Pavia, Italy.

Alessandro Raveane (A)

Department of Biology and Biotechnology 'L. Spallanzani', University of Pavia, via Ferrata 9, 27100 Pavia, Italy.
Laboratory of Hematology-Oncology, European Institute of Oncology IRCCS, via Ripamonti 435, 20141 Milan, Italy.

Andrea Pagano (A)

Department of Biology and Biotechnology 'L. Spallanzani', University of Pavia, via Ferrata 9, 27100 Pavia, Italy.

Francesco Bertolini (F)

Laboratory of Hematology-Oncology, European Institute of Oncology IRCCS, via Ripamonti 435, 20141 Milan, Italy.

Ornella Semino (O)

Department of Biology and Biotechnology 'L. Spallanzani', University of Pavia, via Ferrata 9, 27100 Pavia, Italy.

Alma Balestrazzi (A)

Department of Biology and Biotechnology 'L. Spallanzani', University of Pavia, via Ferrata 9, 27100 Pavia, Italy.

Anca Macovei (A)

Department of Biology and Biotechnology 'L. Spallanzani', University of Pavia, via Ferrata 9, 27100 Pavia, Italy.

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Classifications MeSH