An efficient molecular approach to distinguish chains of measles virus transmission in the elimination phase.
Measles
Measles virus
Molecular epidemiology
Molecular surveillance
Journal
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases
ISSN: 1567-7257
Titre abrégé: Infect Genet Evol
Pays: Netherlands
ID NLM: 101084138
Informations de publication
Date de publication:
07 2021
07 2021
Historique:
received:
24
12
2020
revised:
18
02
2021
accepted:
26
02
2021
pubmed:
5
3
2021
medline:
12
1
2022
entrez:
4
3
2021
Statut:
ppublish
Résumé
Measles viruses continue to spread globally, despite the availability of a safe and effective vaccine. Molecular surveillance of measles virus has become an essential tool to demonstrate whether cascades of infections in a certain region or country are the result of endemic spread or the repeatedly introduction of the virus in contained outbreaks. Currently, molecular surveillance of measles viruses worldwide is mainly based on 450 nucleotides of the C-terminal region of the nucleoprotein (N450). However, as a result of the disappearance of particular measles virus clades over the past decades, this gene segment does not provide sufficient resolution anymore to answer these questions. To increase the molecular resolution, sequence data were collected from three regions of the measles virus genome, the partial non-coding region between the M and F gene (M-F NCR
Identifiants
pubmed: 33662587
pii: S1567-1348(21)00091-5
doi: 10.1016/j.meegid.2021.104794
pii:
doi:
Substances chimiques
RNA, Viral
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
104794Informations de copyright
Copyright © 2021 The Authors. Published by Elsevier B.V. All rights reserved.