Neuronal enhancers are hotspots for DNA single-strand break repair.
Journal
Nature
ISSN: 1476-4687
Titre abrégé: Nature
Pays: England
ID NLM: 0410462
Informations de publication
Date de publication:
05 2021
05 2021
Historique:
received:
28
11
2020
accepted:
17
03
2021
pubmed:
27
3
2021
medline:
5
11
2021
entrez:
26
3
2021
Statut:
ppublish
Résumé
Defects in DNA repair frequently lead to neurodevelopmental and neurodegenerative diseases, underscoring the particular importance of DNA repair in long-lived post-mitotic neurons
Identifiants
pubmed: 33767446
doi: 10.1038/s41586-021-03468-5
pii: 10.1038/s41586-021-03468-5
pmc: PMC9827709
mid: NIHMS1848491
doi:
Substances chimiques
5-Methylcytosine
6R795CQT4H
DNA
9007-49-2
Poly(ADP-ribose) Polymerases
EC 2.4.2.30
Types de publication
Journal Article
Research Support, N.I.H., Intramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
440-444Subventions
Organisme : Medical Research Council
ID : MR/P010121/1
Pays : United Kingdom
Organisme : Intramural NIH HHS
ID : Z01 BC010283
Pays : United States
Commentaires et corrections
Type : CommentIn
Type : CommentIn
Type : CommentIn
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