Smartphone biosensor for point-of-need chemiluminescence detection of ochratoxin A in wine and coffee.
Chemiluminescence
Food safety
Lateral flow immunoassay
Mycotoxins
Ochratoxin A
Point of need
Smartphone
Journal
Analytica chimica acta
ISSN: 1873-4324
Titre abrégé: Anal Chim Acta
Pays: Netherlands
ID NLM: 0370534
Informations de publication
Date de publication:
08 Jun 2021
08 Jun 2021
Historique:
received:
04
01
2021
revised:
08
04
2021
accepted:
11
04
2021
entrez:
24
5
2021
pubmed:
25
5
2021
medline:
27
5
2021
Statut:
ppublish
Résumé
Exposure to mycotoxins, which may contaminate food and feed commodities, represents a serious health risk for consumers. Ochratoxin A (OTA) is one of the most abundant and toxic mycotoxins, thus specific regulations for fixing its maximum admissible levels in foodstuff have been established. Lateral Flow ImmunoAssay (LFIA)-based devices have been proposed as screening tools to avoid OTA contamination along the whole food chain. We report a portable, user-friendly smartphone-based biosensor for the detection and quantification of OTA in wine and instant coffee, which combines the LFIA approach with chemiluminescence (CL) detection. The device employs the smartphone camera as a light detector and uses low-cost, disposable analytical cartridges containing the LFIA strip and all the necessary reagents. The analysis can be carried out at the point of need by non-specialized operators through simple manual operations. The biosensor allows OTA quantitative detection in wine and coffee samples up to 25 μg L
Identifiants
pubmed: 34024424
pii: S0003-2670(21)00341-X
doi: 10.1016/j.aca.2021.338515
pii:
doi:
Substances chimiques
Coffee
0
Ochratoxins
0
ochratoxin A
1779SX6LUY
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
338515Informations de copyright
Copyright © 2021 Elsevier B.V. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.