Smartphone biosensor for point-of-need chemiluminescence detection of ochratoxin A in wine and coffee.

Chemiluminescence Food safety Lateral flow immunoassay Mycotoxins Ochratoxin A Point of need Smartphone

Journal

Analytica chimica acta
ISSN: 1873-4324
Titre abrégé: Anal Chim Acta
Pays: Netherlands
ID NLM: 0370534

Informations de publication

Date de publication:
08 Jun 2021
Historique:
received: 04 01 2021
revised: 08 04 2021
accepted: 11 04 2021
entrez: 24 5 2021
pubmed: 25 5 2021
medline: 27 5 2021
Statut: ppublish

Résumé

Exposure to mycotoxins, which may contaminate food and feed commodities, represents a serious health risk for consumers. Ochratoxin A (OTA) is one of the most abundant and toxic mycotoxins, thus specific regulations for fixing its maximum admissible levels in foodstuff have been established. Lateral Flow ImmunoAssay (LFIA)-based devices have been proposed as screening tools to avoid OTA contamination along the whole food chain. We report a portable, user-friendly smartphone-based biosensor for the detection and quantification of OTA in wine and instant coffee, which combines the LFIA approach with chemiluminescence (CL) detection. The device employs the smartphone camera as a light detector and uses low-cost, disposable analytical cartridges containing the LFIA strip and all the necessary reagents. The analysis can be carried out at the point of need by non-specialized operators through simple manual operations. The biosensor allows OTA quantitative detection in wine and coffee samples up to 25 μg L

Identifiants

pubmed: 34024424
pii: S0003-2670(21)00341-X
doi: 10.1016/j.aca.2021.338515
pii:
doi:

Substances chimiques

Coffee 0
Ochratoxins 0
ochratoxin A 1779SX6LUY

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

338515

Informations de copyright

Copyright © 2021 Elsevier B.V. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Auteurs

Martina Zangheri (M)

Department of Chemistry "Giacomo Ciamician", Alma Mater Studiorum - University of Bologna, Via Selmi 2, 40126, Bologna, Italy; Interdepartmental Centre of Industrial Agrifood Research (CIRI Agrifood), Alma Mater Studiorum, University of Bologna, Piazza Goidanich 60, 47521, Cesena, FC, Italy. Electronic address: martina.zangheri2@unibo.it.

Fabio Di Nardo (F)

Department of Chemistry, University of Turin, Via P. Giuria 5, 10125, Torino, Italy. Electronic address: fabio.dinardo@unito.it.

Donato Calabria (D)

Department of Chemistry "Giacomo Ciamician", Alma Mater Studiorum - University of Bologna, Via Selmi 2, 40126, Bologna, Italy.

Elisa Marchegiani (E)

Department of Chemistry "Giacomo Ciamician", Alma Mater Studiorum - University of Bologna, Via Selmi 2, 40126, Bologna, Italy.

Laura Anfossi (L)

Department of Chemistry, University of Turin, Via P. Giuria 5, 10125, Torino, Italy.

Massimo Guardigli (M)

Department of Chemistry "Giacomo Ciamician", Alma Mater Studiorum - University of Bologna, Via Selmi 2, 40126, Bologna, Italy; Interdepartmental Centre of Industrial Research "Renewable Sources, Environment, Blue Growth, Energy", University of Bologna, Via Angherà 22, Rimini, 47921, Italy.

Mara Mirasoli (M)

Department of Chemistry "Giacomo Ciamician", Alma Mater Studiorum - University of Bologna, Via Selmi 2, 40126, Bologna, Italy; Interuniversity Consortium "Istituto Nazionale Biostrutture e Biosistemi" (INBB) - Viale Delle Medaglie D'Oro 305, 00136, Roma, Italy; Interdepartmental Centre of Industrial Research "Renewable Sources, Environment, Blue Growth, Energy", University of Bologna, Via Angherà 22, Rimini, 47921, Italy.

Claudio Baggiani (C)

Department of Chemistry, University of Turin, Via P. Giuria 5, 10125, Torino, Italy.

Aldo Roda (A)

Department of Chemistry "Giacomo Ciamician", Alma Mater Studiorum - University of Bologna, Via Selmi 2, 40126, Bologna, Italy; Interuniversity Consortium "Istituto Nazionale Biostrutture e Biosistemi" (INBB) - Viale Delle Medaglie D'Oro 305, 00136, Roma, Italy.

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