Exploring Codon Adjustment Strategies towards


Journal

Viruses
ISSN: 1999-4915
Titre abrégé: Viruses
Pays: Switzerland
ID NLM: 101509722

Informations de publication

Date de publication:
23 06 2021
Historique:
received: 21 05 2021
revised: 17 06 2021
accepted: 18 06 2021
entrez: 2 7 2021
pubmed: 3 7 2021
medline: 15 12 2021
Statut: epublish

Résumé

Marine viral sequence space is immense and presents a promising resource for the discovery of new enzymes interesting for research and biotechnology. However, bottlenecks in the functional annotation of viral genes and soluble heterologous production of proteins hinder access to downstream characterization, subsequently impeding the discovery process. While commonly utilized for the heterologous expression of prokaryotic genes, codon adjustment approaches have not been fully explored for viral genes. Herein, the sequence-based identification of a putative prophage is reported from within the genome of

Identifiants

pubmed: 34201869
pii: v13071215
doi: 10.3390/v13071215
pmc: PMC8310279
pii:
doi:

Substances chimiques

Codon 0
Recombinant Proteins 0
Viral Proteins 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

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Auteurs

Hasan Arsın (H)

Department of Biological Sciences, University of Bergen, N-5020 Bergen, Norway.
Centre for Deep Sea Research, University of Bergen, N-5020 Bergen, Norway.

Andrius Jasilionis (A)

Division of Biotechnology, Lund University, P.O. Box 124, SE-221 00 Lund, Sweden.

Håkon Dahle (H)

Centre for Deep Sea Research, University of Bergen, N-5020 Bergen, Norway.
Computational Biology Unit, University of Bergen, N-5020 Bergen, Norway.

Ruth-Anne Sandaa (RA)

Department of Biological Sciences, University of Bergen, N-5020 Bergen, Norway.

Runar Stokke (R)

Department of Biological Sciences, University of Bergen, N-5020 Bergen, Norway.
Centre for Deep Sea Research, University of Bergen, N-5020 Bergen, Norway.

Eva Nordberg Karlsson (E)

Division of Biotechnology, Lund University, P.O. Box 124, SE-221 00 Lund, Sweden.

Ida Helene Steen (IH)

Department of Biological Sciences, University of Bergen, N-5020 Bergen, Norway.
Centre for Deep Sea Research, University of Bergen, N-5020 Bergen, Norway.

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Classifications MeSH