Using surfactants as matrix for the matrix-assisted laser desorption/ionization time of flight mass spectrometry (MALDI-TOF-MS) of amino acids: Sodium dodecyl sulfate (SDS) and sodium octyl sulfate (SOS).
Amino acids
Direct LDI
MALDI-TOF-MS
Sodium attachment
Sodium dodecyl sulfate
Journal
Biophysical chemistry
ISSN: 1873-4200
Titre abrégé: Biophys Chem
Pays: Netherlands
ID NLM: 0403171
Informations de publication
Date de publication:
11 2021
11 2021
Historique:
received:
04
06
2021
revised:
21
07
2021
accepted:
10
08
2021
pubmed:
5
9
2021
medline:
22
3
2022
entrez:
4
9
2021
Statut:
ppublish
Résumé
In the present study, the applicability of two surfactants including sodium dodecyl sulfate (SDS) and sodium octyl sulfate (SOS) as the matrix for the Matrix-Assisted Laser Desorption/Ionization (MALDI) of several amino acids (phenylalanine (Phe), valine (Val), proline (Pro), alanine (Ala), and tyrosine (Tyr)) is investigated. Also, the effect of the material of the repeller plate of the ionization part of the used time of flight (TOF) mass spectrometer on the spectral patterns of the amino acids is studied. Furthermore, the recorded MALDI spectra of amino acids are compared with their corresponding direct laser desorption/ionization (direct-LDI) TOF mass spectra. It is observed that the SDS is an appropriate matrix for the Na
Identifiants
pubmed: 34481166
pii: S0301-4622(21)00149-6
doi: 10.1016/j.bpc.2021.106667
pii:
doi:
Substances chimiques
Alkanesulfonic Acids
0
Amino Acids
0
Surface-Active Agents
0
Sodium Dodecyl Sulfate
368GB5141J
1-octanesulfonic acid
DU4821I15A
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
106667Informations de copyright
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