Combined toxic effects of aflatoxin B


Journal

Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288

Informations de publication

Date de publication:
10 09 2021
Historique:
received: 10 05 2021
accepted: 21 07 2021
entrez: 11 9 2021
pubmed: 12 9 2021
medline: 15 12 2021
Statut: epublish

Résumé

In this study, the toxic effects of aflatoxin B

Identifiants

pubmed: 34508115
doi: 10.1038/s41598-021-95879-7
pii: 10.1038/s41598-021-95879-7
pmc: PMC8433416
doi:

Substances chimiques

Protective Agents 0
Aflatoxin B1 9N2N2Y55MH
Resveratrol Q369O8926L

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

18081

Informations de copyright

© 2021. The Author(s).

Références

Yentür, G. & Er, B. The evaluation of the aflatoxin presence in foods. Türk Hij. Den. Biyol. Derg. 69(1), 41–52 (2011).
doi: 10.5505/TurkHijyen.2012.54154
Şener, S. Mycotoxins from food safety perspective. Türkiye Klinikleri J. Surg. Med. Sci. 2(46), 135–139 (2006).
O’Riordan, M. J. & Wilkinson, M. G. A survey of the incidence and level of aflatoxin contamination in a range of imported spice preparations on the Irish retail market. Food Chem. 107(4), 1429–1435 (2008).
doi: 10.1016/j.foodchem.2007.09.073
Agag, B. I. Mycotoxins in foods and feeds: 1-aflatoxins. Ass. Univ. Bull. Environ. Res. 7(1), 173–191 (2004).
Larsson, P. & Tjalve, H. Intranasal instillation of Aflatoxin B1 in rats: Bio activation in the nasal mucosa and neuronal transport to the olfactory bulb. Toxicol. Sci. 55, 383–391 (2000).
pubmed: 10828271 doi: 10.1093/toxsci/55.2.383
Coulombe, R.A. Non-hepatic effects and biotransformations of aflatoxin B1 in The toxicology of aflatoxins: Human health, veterinary and agricultural significance (ed. Eaton, D.L and Groopman, J.D.) 89–101 (Orlando, 1994).
Hussein, H. S. & Brasel, J. M. Toxicity, metabolism, and impact of mycotoxins on humans and animals. Toxicology 167(2), 101–134 (2001).
pubmed: 11567776 doi: 10.1016/S0300-483X(01)00471-1
Santini, A., & Ritieni, A. Aflatoxins: Risk, exposure and remediation in Aflatoxins: Recent advances and future prospects (ed. RazzaghiAbyaneh M.) 343–376 (UK, 2013).
Bbosa, G. S. et al. Review of the biological and health effects of aflatoxins on body organs and body systems. Aflatoxins Recent Adv. Future Prospects. https://doi.org/10.5772/51201 (2013).
doi: 10.5772/51201
Ide, S. et al. Mu opioid receptor-dependent and independent components in effects of tramadol. Neuropharmacology 51(3), 651–658 (2006).
pubmed: 16793069 doi: 10.1016/j.neuropharm.2006.05.008
Santana, L., Uriarte, E., Roleira, F., Milhazes, N. & Borges, F. Furocoumarins in medicinal chemistry. Synthesis, natural occurrence and biological activity. Curr. Med. Chem. 11(24), 3239–3261 (2004).
pubmed: 15579011 doi: 10.2174/0929867043363721
Yurdun, T. & Öz, V. A study on aflatoxins in various foods, spices and feedstuffs by high performance liquid chromatography. J. Fac. Pharm. Istanbul. 31, 11–16 (1995).
Görün, M.S. & Süzer, Ö. B. Herbal medicines in Süzer pharmacology (ed. Süzer, Ö.) 533–539 (İstanbul, 2004).
Stein, C. M. Are herbal products dietary supplements or drugs? An important question for public safety. Cli. Pharmacol. Ther. 71, 411–423 (2002).
doi: 10.1067/mcp.2002.125975
Droge, W. Free radicals in the physiological control of cell function. Physiol. Rev. 82(1), 47–95 (2002).
pubmed: 11773609 doi: 10.1152/physrev.00018.2001
Romano, A. D., Serviddio, G., De Matthaeis, A., Bellanti, F. & Vendemiale, G. Oxidative stress and aging. J. Nephrol. 23, 29–36 (2010).
Leonard, S. S. et al. Resveratrol scavenges reactive oxygen species and affects radical-induced cellular responses. Biochem. Biophys. Res. Commun. 309(4), 1017–1026 (2003).
pubmed: 13679076 doi: 10.1016/j.bbrc.2003.08.105
Guarente, L. Sirtuins, aging, and medicine. N. Engl. J. Med. 364(23), 2235–2244 (2011).
pubmed: 21651395 doi: 10.1056/NEJMra1100831
Kitada, M., Kume, S., Takeda-Watanabe, A., Kanasaki, K. & Koya, D. Sirtuins and renal diseases: Relationship with aging and diabetic nephropathy. Clin. Sci. 124(3), 153–164 (2013).
doi: 10.1042/CS20120190
Theumer, M. G. et al. Subchronic mycotoxicoses in Wistar rats: Assessment of the in vivo and in vitro genotoxicity induced by fumonisins and aflatoxin B1, and oxidative stress biomarkers status. Toxicology 268(1–2), 104–110 (2010).
pubmed: 20015463 doi: 10.1016/j.tox.2009.12.007
Li, Y., Cao, Z. & Zhu, H. Upregulation of endogenous antioxidants and phase 2 enzymes by the red wine polyphenol, resveratrol in cultured aortic smooth muscle cells leads to cytoprotection against oxidative and electrophilic stress. Pharmacol. Res. 53(1), 6–15 (2006).
pubmed: 16169743 doi: 10.1016/j.phrs.2005.08.002
Gülçin, İ. Antioxidant properties of resveratrol: A structure–activity insight. Innov. Food Sci. Emerg. Technol. 11(1), 210–218 (2010).
doi: 10.1016/j.ifset.2009.07.002
Ruch, R. J., Cheng, S. J. & Klaunig, J. E. Prevention of cytotoxicity and inhibition of intracellular communication by antioxidant catechins isolated from Chinese green tea. Carcinogenesis 10, 1003–1008 (1989).
pubmed: 2470525 doi: 10.1093/carcin/10.6.1003
Blois, M. S. Antioxidant determinations by the use of a stable free radical. Nature 181, 1199–1200 (1958).
doi: 10.1038/1811199a0
Butler, W. H., Greenblatt, M. & Lijinsky, W. Carcinogenesis in rats by aflatoxins B1, G1, and B2. Cancer Res. 29(12), 2206–2211 (1969).
pubmed: 4318833
Özatik, F. Y., Özatik, O., Yiğitaslan, S., Ünel, Ç. Ç. & Erol, K. Protective role of resveratrol on testicular germ cells in mice with testicular toxicity. Turk. J. Urol. 43(4), 444 (2017).
pubmed: 29201506 pmcid: 5687206 doi: 10.5152/tud.2017.34101
Cavusoglu, K., Yapar, K., Yalcın, E. & Oruc, E. Protective effect of Royal Jelly on some biochemical parameters in cadmium-treated albino mice. Fresenius Environ. Bull. 19(10), 2164–2169 (2010).
Yalcin, E., Oruc, E., Cavusoglu, K. & Yapar, K. Protective effect of grape seed extract on doxorubicin-induced nephrotoxicity and hepatotoxicity in albino mice. Fresenius Environ. Bull. 19(10), 2151–2158 (2010).
Yoshioka, T., Kawada, K., Shimada, T. & Mori, M. Lipid peroxidation in maternal and cord blood and protective mechanism against activated-oxygen toxicity in the blood. Am. J. Obstet. Gynecol. 135(3), 372–376 (1979).
pubmed: 484629 doi: 10.1016/0002-9378(79)90708-7
Beutler, E. Improved method for the determination of blood glutathione. J. Lab. Clin. Med. 61, 882–888 (1963).
pubmed: 13967893
Fenech, M. et al. Human micronucleus project. HUMN project: Detailed description of the scoring criteria for the cytokinesis-block micronucleus assay using isolated human lymphocyte cultures. Mutat. Res. Genet. Toxicol. Environ. Mutagen. 534(1), 65–75 (2003).
doi: 10.1016/S1383-5718(02)00249-8
Taşlı, B., Çiçek, F., Yalçın, E., Demirtaş, G. & Çavuşoğlu, K. The protective effect of green tea extract on formaldehyde toxicity: Genotoxic evaluation in swiss albino mice. Cumhuriyet Sci. J. 36(2), 63–73 (2015).
Te-Hsiu, M. A., Zhou, X., Loarco, G. F., Arreola, G. G. & Lecona, S. U. Mouse erythrocyte micronucleus (MUS-EMN) assay on the clastogenicity of industrial wastewater. Rev. Int. Contam. Ambient. 11, 95–98 (1995).
Acar, A., Yalçın, E., Yapar, K. & Çavuşoğlu, K. Protective effect of royal jelly against changes in physiological and genetic structure promoted by lambda cyhalothrin. Black Sea 1st International Multidisciplinary Scientific Studies Congress. 463–469 (2019).
Savage, J. R. Classification and relationships of induced chromosomal structural changes. J. Med. Genet. 13, 103–122 (1976).
pubmed: 933108 pmcid: 1013369 doi: 10.1136/jmg.13.2.103
Murcia, M. A. & Martinez-Tome, M. Antioxidant activity of resveratrol compared with common food additives. J. Food Prot. 64(3), 379–384 (2001).
pubmed: 11252483 doi: 10.4315/0362-028X-64.3.379
Oguz, H. & Kurtoglu, V. Effect of clinoptilolite on performance of broiler chickens during experimental aflatoxicosis. Br. Poult. Sci. 41(4), 512–517 (2000).
pubmed: 11225564 doi: 10.1080/713654953
Davies, M. J. Role of lipolysis and lipogenesis in the development of diet-induced obesity. Old Dominion University, Eastern Virginia Medial School, PhD Thesis. 1–152 (2000).
Arvind, M. N. & Churchil, R. R. Effect of dietary esterified glucomannan on performance of broilers exposed to aflatoxin. Indian J. Anim. Res. 49(5), 658–661 (2015).
Dimitri, R. A., Gabal, M. A. & Saleh, N. Effect of aflatoxin ingestion in feed on body weight gain and tissue residues in rabbits. Mycoses 41(1–2), 87–91 (1998).
pubmed: 9610142 doi: 10.1111/j.1439-0507.1998.tb00384.x
Cardoso, V. S. et al. Efficacy of piperine in reducing the effects of aflatoxin intoxication in broiler chickens: a preliminary report. Arq. Bras. Med. Vet. Zootec. 63(2), 495 (2011).
doi: 10.1590/S0102-09352011000200031
Jeon, S. M., Lee, S. A. & Choi, M. S. Antiobesity and vasoprotective effects of resveratrol in apoE-deficient mice. J. Med. Food. 17(3), 310–316 (2014).
pubmed: 24433070 pmcid: 3961783 doi: 10.1089/jmf.2013.2885
Do Amaral, C. L. et al. Resveratrol attenuates cisplatin-induced nephrotoxicity in rats. Arch. Toxicol. 82(6), 363–370 (2008).
pubmed: 18026934 doi: 10.1007/s00204-007-0262-x
Karaca, A., Yilmaz, S., Kaya, E. & Altun, S. The effect of lycopene on hepatotoxicity of aflatoxin B1 in rats. Arch. Physiol. Biochem. 8(5), 1–8 (2019).
Anderson, F. H., Zeng, L., Rock, N. R. & Yoshida, E. M. An assessment of the clinical utility of serum ALT and AST in chronic hepatitis C. Hepatol. Res. 18(1), 63–71 (2000).
pubmed: 10838037 doi: 10.1016/S1386-6346(99)00085-6
Eraslan, G. et al. The effects of diosmin on aflatoxin-induced liver and kidney damage. Environ. Sci. Pollut. Res. 24(36), 27931–27941 (2017).
doi: 10.1007/s11356-017-0232-7
Han, X. Y., Huang, Q. C., Li, W. F., Jiang, J. F. & Xu, Z. R. Changes in growth performance, digestive enzyme activities and nutrient digestibility of cherry valley ducks in response to aflatoxin B1 levels. Livest. Sci. 119(1–3), 216–220 (2008).
doi: 10.1016/j.livsci.2008.04.006
Bakeer, A. M., Farid, A. S. & GadElKarim, M. F. The hepatotoxic and nephrotoxic effects of mycotoxin in broiler chickens. BVMJ. 25, 29–45 (2013).
Gowda, S. et al. Markers of renal function tests. N. Am. J. Med. Sci. 2(4), 170 (2010).
pubmed: 22624135 pmcid: 3354405
Verma, R. J. & Kolhe, A. S. Altered creatine and creatinine concentrations in the serum and urine of aflatoxin-fed rabbits. Med. Sci. Res. 26(6), 427–428 (1998).
Şener, G. et al. Protective effects of resveratrol against acetaminophen-induced toxicity in mice. Hepatol. Res. 35(1), 62–68 (2006).
pubmed: 16595188 doi: 10.1016/j.hepres.2006.02.005
Palsamy, P. & Subramanian, S. Resveratrol protects diabetic kidney by attenuating hyperglycemia-mediated oxidative stress and renal inflammatory cytokines via Nrf2–Keap1 signaling. Biochim. Biophys. Acta Mol. Basis Dis. 1812(7), 719–731 (2011).
doi: 10.1016/j.bbadis.2011.03.008
Ezekiel, C. N., Alabi, O. A., Anokwuru, C. P. & Oginni, O. Studies on dietary aflatoxin-induced genotoxicity using two in vivo bioassays. Arch. Appl. Sci. Res. 3(2), 97–106 (2011).
Jacotot, E., Ferri, K. F. & Kroemer, G. Apoptosis and cell cycle: Distinct check-points with overlapping upstream control. Pathol. Biol. 48(3), 271–279 (2000).
pubmed: 10858959
Cuypers, A. et al. Cadmium stress: An oxidative challenge. Biometals 23(5), 927–940 (2010).
pubmed: 20361350 doi: 10.1007/s10534-010-9329-x
Nawrot, T. S. et al. Cadmium-related mortality and long-term secular trends in the cadmium body burden of an environmentally exposed population. Environ. Health Perspect. 116(12), 1620–1628 (2008).
pubmed: 19079711 pmcid: 2599754 doi: 10.1289/ehp.11667
Shen, H. M., Shi, C. Y., Lee, H. P. & Ong, C. N. Aflatoxin B1-induced lipid peroxidation in rat liver. Toxicol. Appl. Pharmacol. 127(1), 145–150 (1994).
pubmed: 8048046 doi: 10.1006/taap.1994.1148
Kasdallah-Grissa, A. et al. Protective effect of resveratrol on ethanol-induced lipid peroxidation in rats. Alcohol Alcohol. 41(3), 236–239 (2006).
pubmed: 16517551 doi: 10.1093/alcalc/agh256
Kerksick, C. & Willoughby, D. The antioxidant role of glutathione and N-acetyl-cysteine supplements and exercise-induced oxidative stress. J. Int. Soc. Sports Nutr. 2(2), 38 (2005).
pubmed: 18500954 pmcid: 2129149 doi: 10.1186/1550-2783-2-2-38
Kheir Eldin, A. A., Motawi, T. M. & Sadik, N. A. Effect of some natural antioxidants on aflatoxin B1-induced hepatic toxicity. Excli J. 7, 119–131 (2008).
Von Ledebur, M. & Schmid, W. The micronucleus test methodological aspects. Mutat. Res. Fundum. Mol. Mech. 19(1), 109–117 (1973).
doi: 10.1016/0027-5107(73)90118-8
Maier, P. & Schmid, W. T. model mutagens evaluated by the micronucleus test. Mutat. Res. Genet. Toxicol. 40(4), 325–337 (1976).
doi: 10.1016/0165-1218(76)90031-8
Högstedt, B. & Karlsson, A. The size of micronuclei in human lymphocytes varies according to inducing agent used. Mutat. Res. 156, 229–232 (1985).
pubmed: 3923348 doi: 10.1016/0165-1218(85)90067-9
Corcuera, L. A. et al. Genotoxicity of Aflatoxin B1 and Ochratoxin A after simultaneous application of the in vivo micronucleus and comet assay. Food Chem. Toxicol. 76, 116–124 (2015).
pubmed: 25530104 doi: 10.1016/j.fct.2014.12.003
Guengerich, F. P. Forging the links between metabolism and carcinogenesis. Mutat. Res. 488(3), 195–209 (2001).
pubmed: 11397649 doi: 10.1016/S1383-5742(01)00059-X
Bailey, E. A., Iyer, R. S., Stone, M. P., Harris, T. M. & Essigmann, J. M. Mutational properties of the primary aflatoxin B1-DNA adduct. PNAS 93(4), 1535–1539 (1996).
pubmed: 8643667 pmcid: 39975 doi: 10.1073/pnas.93.4.1535
Kovalchuk, O. et al. The Allium cepa chromosome aberration test reliably measures genotoxicity of soils of inhabited areas in the Ukraine contaminated by the Chernobyl accident. Mutat. Res. 415, 47–57 (1998).
pubmed: 9711261 doi: 10.1016/S1383-5718(98)00053-9
Fetaih, H. A., Dessouki, A. A., Hassanin, A. A. & Tahan, A. S. Toxopathological and cytogenetic effects of aflatoxin B1 (AFB1) on pregnant rats. Pathol. Res. Pract. 210(12), 1079–1089 (2014).
pubmed: 25023881 doi: 10.1016/j.prp.2014.06.001
Descartes, M., Korf, B.R. & Mikhail, F.M. Chromosomes and chromosomal abnormalities in Swaiman’s pediatric neurology (ed. Swaiman, K.F.) 268–276 (Amsterdam, 2018).
Fadl-Allah, E. M., Mahmoud, M. H., Abd El-Twab, M. H., & Helmey, R. K. Aflatoxin B1 induces chromosomal aberrations and 5S rDNA alterations in durum wheat. J. Assoc. Arab. Univ. Basic Appl. Sci. 10(1), 8–14 (2011).
Theodotou, M. et al. Effect of resveratrol on non-alcoholic fatty liver disease. Exp. Ther. Med. 18(1), 559–565 (2019).
pubmed: 31316594 pmcid: 6566048
Ara, C. et al. Protective effect of resveratrol against renal oxidative stress in cholestasis. Ren. Fail. 27(4), 435–440 (2005).
pubmed: 16060133 doi: 10.1081/JDI-65221
Losa, G. A. Resveratrol modulates apoptosis and oxidation in human blood mononuclear cells. Eur. J. Clin. Investig. 33(9), 818–823 (2003).
doi: 10.1046/j.1365-2362.2003.01219.x
Kundu, J. K. & Surh, Y. J. Molecular basis of chemoprevention by resveratrol: NF-κB and AP-1 as potential targets. Mutat. Res. Fundum. Mol. Mech. 555(1–2), 65–80 (2004).
doi: 10.1016/j.mrfmmm.2004.05.019
Macar, T. K., Macar, O., Yalçın, E. & Çavuşoğlu, K. Resveratrol ameliorates the physiological, biochemical, cytogenetic, and anatomical toxicities induced by copper (II) chloride exposure in Allium cepa L.. Environ. Sci. Pollut. Res. 27(1), 657–667 (2020).
doi: 10.1007/s11356-019-06920-2

Auteurs

Alperen Gündüz (A)

Department of Biology, Faculty of Science and Art, Giresun University, 28200, Giresun, Turkey.

Emine Yalçın (E)

Department of Biology, Faculty of Science and Art, Giresun University, 28200, Giresun, Turkey.

Kültiğin Çavuşoğlu (K)

Department of Biology, Faculty of Science and Art, Giresun University, 28200, Giresun, Turkey. kultigincavusoglu@mynet.com.

Articles similaires

Robotic Surgical Procedures Animals Humans Telemedicine Models, Animal

Odour generalisation and detection dog training.

Lyn Caldicott, Thomas W Pike, Helen E Zulch et al.
1.00
Animals Odorants Dogs Generalization, Psychological Smell
Animals TOR Serine-Threonine Kinases Colorectal Neoplasms Colitis Mice
Animals Tail Swine Behavior, Animal Animal Husbandry

Classifications MeSH