Cationization of neutral small molecules by site-specific carboxylation of 10-phenyl-10

Lasers Oligosaccharides Phenothiazines Protons Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

Journal

The Analyst
ISSN: 1364-5528
Titre abrégé: Analyst
Pays: England
ID NLM: 0372652

Informations de publication

Date de publication:
13 Sep 2021
Historique:
entrez: 13 9 2021
pubmed: 14 9 2021
medline: 16 9 2021
Statut: epublish

Résumé

It is a pre-requisite to ionize analyte molecules efficiently for detection by laser desorption/ionization mass spectrometry. Here, we report a conceptual demonstration of cationizing neutral small molecules which are typically difficult to be ionized with the traditional organic matrices due to their low proton/cation affinity values. Our strategy features generating radical cations from site-specifically carboxylated 10-(4-carboxyphenyl)-10

Identifiants

DOI: 10.1039/d1an01111a PMID: 34515705
pubmed: 34515705
doi: 10.1039/d1an01111a
doi:

Substances chimiques

Oligosaccharides 0
Phenothiazines 0
Protons 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

5533-5541

Auteurs

Chongqing Ma (C)

Institute of Functional Nano and Soft Materials (FUNSOM), Jiangsu Key Laboratory for Carbon-Based Functional Materials and Devices, Soochow University, Suzhou, Jiangsu Province 215123, China. jliu@suda.edu.cn.

Tianrong Yu (T)

Institute of Functional Nano and Soft Materials (FUNSOM), Jiangsu Key Laboratory for Carbon-Based Functional Materials and Devices, Soochow University, Suzhou, Jiangsu Province 215123, China. jliu@suda.edu.cn.

Yue Liu (Y)

Institute of Functional Nano and Soft Materials (FUNSOM), Jiangsu Key Laboratory for Carbon-Based Functional Materials and Devices, Soochow University, Suzhou, Jiangsu Province 215123, China. jliu@suda.edu.cn.

Rui Shi (R)

Institute of Functional Nano and Soft Materials (FUNSOM), Jiangsu Key Laboratory for Carbon-Based Functional Materials and Devices, Soochow University, Suzhou, Jiangsu Province 215123, China. jliu@suda.edu.cn.

Rui Lv (R)

Institute of Functional Nano and Soft Materials (FUNSOM), Jiangsu Key Laboratory for Carbon-Based Functional Materials and Devices, Soochow University, Suzhou, Jiangsu Province 215123, China. jliu@suda.edu.cn.

Ruochen Guo (R)

Institute of Functional Nano and Soft Materials (FUNSOM), Jiangsu Key Laboratory for Carbon-Based Functional Materials and Devices, Soochow University, Suzhou, Jiangsu Province 215123, China. jliu@suda.edu.cn.

Qinghua Cao (Q)

Institute of Functional Nano and Soft Materials (FUNSOM), Jiangsu Key Laboratory for Carbon-Based Functional Materials and Devices, Soochow University, Suzhou, Jiangsu Province 215123, China. jliu@suda.edu.cn.

Gaole Dai (G)

Institute of Functional Nano and Soft Materials (FUNSOM), Jiangsu Key Laboratory for Carbon-Based Functional Materials and Devices, Soochow University, Suzhou, Jiangsu Province 215123, China. jliu@suda.edu.cn.
ORCID: 0000-0003-4270-3604

Yu Zhao (Y)

Institute of Functional Nano and Soft Materials (FUNSOM), Jiangsu Key Laboratory for Carbon-Based Functional Materials and Devices, Soochow University, Suzhou, Jiangsu Province 215123, China. jliu@suda.edu.cn.
ORCID: 0000-0002-6184-2530

Jian Liu (J)

Institute of Functional Nano and Soft Materials (FUNSOM), Jiangsu Key Laboratory for Carbon-Based Functional Materials and Devices, Soochow University, Suzhou, Jiangsu Province 215123, China. jliu@suda.edu.cn.
ORCID: 0000-0002-0095-8978

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Classifications MeSH

questionsmedicales.fr › Équipement et fournitures › Équipement et fournitures pour les applications des radiations › Lasers › Cationization of neutral small molecules by...
questionsmedicales.fr › Glucides › Polyosides › Oligosaccharides › Cationization of neutral small molecules by...
questionsmedicales.fr › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérocycliques 3 noyaux › Phénothiazines › Cationization of neutral small molecules by...
questionsmedicales.fr › Phénomènes physiques › Particules élémentaires › Nucléons › Protons › Cationization of neutral small molecules by...
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Spectrométrie de masse › Spectrométrie de masse MALDI › Cationization of neutral small molecules by...